AXIN2
出典: フリー百科事典『ウィキペディア(Wikipedia)』 (2022/05/12 08:29 UTC 版)
AXIN2は、ヒトではAXIN2遺伝子によってコードされるタンパク質である。Axil(axin-like protein)、コンダクチン(conductin)の名称でも知られる[5][6]。
- ^ a b c GRCh38: Ensembl release 89: ENSG00000168646 - Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000000142 - Ensembl, May 2017
- ^ Human PubMed Reference:
- ^ Mouse PubMed Reference:
- ^ “Cloning of the human homolog of conductin (AXIN2), a gene mapping to chromosome 17q23-q24”. Genomics 55 (3): 341–4. (May 1999). doi:10.1006/geno.1998.5650. PMID 10049590.
- ^ a b c “Entrez Gene: AXIN2 axin 2 (conductin, axil)”. 2022年5月12日閲覧。
- ^ “Evaluation of AXIN1 and AXIN2 as targets of tankyrase inhibition in hepatocellular carcinoma cell lines”. Scientific Reports 11 (1): 7470. (April 2021). doi:10.1038/s41598-021-87091-4. PMC 8018973. PMID 33811251 .
- ^ “The links between axin and carcinogenesis”. J. Clin. Pathol. 58 (3): 225–36. (March 2005). doi:10.1136/jcp.2003.009506. PMC 1770611. PMID 15735151 .
- ^ “The genetics of human tooth agenesis: new discoveries for understanding dental anomalies”. Am J Orthod Dentofacial Orthop 117 (6): 650–6. (June 2000). doi:10.1016/s0889-5406(00)70173-9. PMID 10842107.
- ^ a b “Mutations in AXIN2 Cause Familial Tooth Agenesis and Predispose to Colorectal Cancer”. Am. J. Hum. Genet. 74 (5): 1043–50. (May 2004). doi:10.1086/386293. PMC 1181967. PMID 15042511 .
- ^ “Axis inhibition protein 2 (AXIN2) polymorphisms may be a risk factor for selective tooth agenesis”. J. Hum. Genet. 51 (3): 262–6. (2006). doi:10.1007/s10038-005-0353-6. PMID 16432638.
- ^ Longtin, Robert (2004-07-07). “Chew on this: mutation may be responsible for tooth loss, colon cancer”. Journal of the National Cancer Institute 96 (13): 987–989. doi:10.1093/jnci/96.13.987. ISSN 1460-2105. PMID 15240779 .
- ^ “Hot spots in beta-catenin for interactions with LEF-1, conductin and APC”. Nat. Struct. Biol. 7 (9): 800–7. (September 2000). doi:10.1038/79039. PMID 10966653.
- ^ “The ankyrin repeat protein Diversin recruits Casein kinase Iε to the β-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling”. Genes Dev. 16 (16): 2073–84. (August 2002). doi:10.1101/gad.230402. PMC 186448. PMID 12183362 .
- 1 AXIN2とは
- 2 AXIN2の概要
- 3 機能
- 4 関連文献
- AXIN2のページへのリンク