Convolutional encoder-decoder for breast mass segmentation in digital breast tomosynthesis

Jun Zhang; Sujata V. Ghate; Lars J. Grimm; Ashirbani Saha; Elizabeth Hope Cain; Zhe Zhu; Maciej A. Mazurowski

doi:10.1117/12.2295437

27 February 2018 Convolutional encoder-decoder for breast mass segmentation in digital breast tomosynthesis

Jun Zhang, Sujata V. Ghate, Lars J. Grimm, Ashirbani Saha, Elizabeth Hope Cain, Zhe Zhu, Maciej A. Mazurowski

Author Affiliations +

Proceedings Volume 10575, Medical Imaging 2018: Computer-Aided Diagnosis; 105752V (2018) https://doi.org/10.1117/12.2295437
Event: SPIE Medical Imaging, 2018, Houston, Texas, United States

Abstract

Digital breast tomosynthesis (DBT) is a relatively new modality for breast imaging that can provide detailed assessment of dense tissue within the breast. In the domains of cancer diagnosis, radiogenomics, and resident education, it is important to accurately segment breast masses. However, breast mass segmentation is a very challenging task, since mass regions have low contrast difference between their neighboring tissues. Notably, the task might become more difficult in cases that were assigned BI-RADS 0 category since this category includes many lesions that are of low conspicuity and locations that were deemed to be overlapping normal tissue upon further imaging and were not sent to biopsy. Segmentation of such lesions is of particular importance in the domain of reader performance analysis and education. In this paper, we propose a novel deep learning-based method for segmentation of BI-RADS 0 lesions in DBT. The key components of our framework are an encoding path for local-to-global feature extraction, and a decoding patch to expand the images. To address the issue of limited training data, in the training stage, we propose to sample patches not only in mass regions but also in non-mass regions. We utilize a Dice-like loss function in the proposed network to alleviate the class-imbalance problem. The preliminary results on 40 subjects show promise of our method. In addition to quantitative evaluation of the method, we present a visualization of the results that demonstrate both the performance of the algorithm as well as the difficulty of the task at hand.

Citation Download Citation

Jun Zhang, Sujata V. Ghate, Lars J. Grimm, Ashirbani Saha, Elizabeth Hope Cain, Zhe Zhu, and Maciej A. Mazurowski "Convolutional encoder-decoder for breast mass segmentation in digital breast tomosynthesis", Proc. SPIE 10575, Medical Imaging 2018: Computer-Aided Diagnosis, 105752V (27 February 2018); https://doi.org/10.1117/12.2295437

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

;

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE