In vivo reconstruction of coronary artery and bioresorbable stents from intracoronary optical coherence tomography

Yingguang Li; Niels R. Holm; Zhenyu Fei; Jouke Dijkstra; Emil N. Holck; Evald Høj Christiansen; Johan H. C. Reiber; Shengxian Tu

doi:10.1117/12.2293711

13 March 2018 In vivo reconstruction of coronary artery and bioresorbable stents from intracoronary optical coherence tomography

Yingguang Li, Niels R. Holm, Zhenyu Fei, Jouke Dijkstra, Emil N. Holck, Evald Høj Christiansen, Johan H. C. Reiber, Shengxian Tu

Author Affiliations +

Proceedings Volume 10576, Medical Imaging 2018: Image-Guided Procedures, Robotic Interventions, and Modeling; 1057622 (2018) https://doi.org/10.1117/12.2293711
Event: SPIE Medical Imaging, 2018, Houston, Texas, United States

Abstract

The implantation of bioresorbable scaffolds (BRS) alters the local hemodynamic environment. Computational fluid dynamics (CFD) allows evaluation of local flow pattern, shear stress (SS) and Pressure_distal/ Pressure_approximal (Pd/Pa). The accuracy of CFD results relies to a great extent on the reconstruction of the 3D geometrical model. The aim of this study was to develop a new approach for in vivo reconstruction of coronary tree and BRS by fusion of Optical Coherence Tomography (OCT) and X-ray angiography. Ten patients enrolled in the BIFSORB pilot study with BRS implanted in coronary bifurcations were included for analysis. All patients underwent OCT of the target vessel after BRS implantation in the main vessel. Coronary 3D reconstruction was performed creating two geometrical models: one was angiography model and the other was OCT model with the implanted BRS. CFD analysis was performed separately on these two models. The main vessel was divided into portions of 0.15 mm length and 0.15mm arc width for point-perpoint comparison of SS between the two models. Reconstruction of the implanted BRS in naturally bent shape was successful in all cases. SS was compared in the matched 205463 portions of the two models. The divergence of shear stress was higher in the OCT model (mean±SD: 2.27 ± 3.95 Pa, maximum: 142.48 Pa) than that in the angiography model (mean±SD: 2.05 ± 3.12 Pa, maximum: 83.63 Pa). Pd/Pa values were lower in the OCT model than in the angiography model for both main vessels and side branches (mean±SD: 0.979 ± 0.009 versus 0.984 ± 0.011, and 0.951 ± 0.068 versus 0.966 ± 0.051). Reconstruction of BRS in naturally bent shape after implantation is feasible. It allows detailed analysis of local flow pattern, including shear stress and Pd/Pa in vivo.

Citation Download Citation

Yingguang Li, Niels R. Holm, Zhenyu Fei, Jouke Dijkstra, Emil N. Holck, Evald Høj Christiansen, Johan H. C. Reiber, and Shengxian Tu "In vivo reconstruction of coronary artery and bioresorbable stents from intracoronary optical coherence tomography", Proc. SPIE 10576, Medical Imaging 2018: Image-Guided Procedures, Robotic Interventions, and Modeling, 1057622 (13 March 2018); https://doi.org/10.1117/12.2293711

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
7 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

3D modeling

Optical coherence tomography

Angiography

Arteries

3D image processing

Protactinium

Image fusion

Show All Keywords

Keywords/Phrases

Search In:

Publication Years