Overlay of neuromagnetic current-density images and morphological MR images

Manfred Fuchs; Hans-Aloys Wischmann; Olaf Doessel

doi:10.1117/12.131120

22 September 1992 Overlay of neuromagnetic current-density images and morphological MR images

Manfred Fuchs, Hans-Aloys Wischmann, Olaf Doessel

Author Affiliations +

Proceedings Volume 1808, Visualization in Biomedical Computing '92; (1992) https://doi.org/10.1117/12.131120
Event: Visualization in Biomedical Computing, 1992, Chapel Hill, NC, United States

Abstract

Neuromagnetic imaging is a relatively new diagnostic tool for examination of electric activities in the nervous system. It is based on the noninvasive detection of extremely weak magnetic fields around the human body with superconducting quantum interference device (SQUID) detectors. `Equivalent current dipoles' and linear estimation reconstructions of current distributions both with spherical volume conductor models are used to localize the neural activity. For practical use in medical diagnosis a combination of the abstract neuromagnetic images with magnetic resonance (MR)- or computer tomography (CT)-images is required in order to match the functional activity with anatomy and morphology. The neuromagnetic images can be overlayed onto three-dimensional morphological images with spatially arbitrarily selectable slices. The matching of both imaging modalities is discussed. Based on the detection of auditory evoked magnetic fields, neuromagnetic images are reconstructed with linear estimation theory algorithms. The MR images are used as a-priori information of the volume conductor geometry and they allow an attachment of functional and morphological properties.

Citation Download Citation

Manfred Fuchs, Hans-Aloys Wischmann, and Olaf Doessel "Overlay of neuromagnetic current-density images and morphological MR images", Proc. SPIE 1808, Visualization in Biomedical Computing '92, (22 September 1992); https://doi.org/10.1117/12.131120

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