Transit dosimetry in dynamic IMRT with an a-Si EPID | Medical & Biological Engineering & Computing Skip to main content

Advertisement

Log in

Transit dosimetry in dynamic IMRT with an a-Si EPID

  • Original Article
  • Published:
Medical & Biological Engineering & Computing Aims and scope Submit manuscript

Abstract

Using an amorphous silicon (a-Si) EPID for transit dosimetry requires detailed characterization of its dosimetric response in a variety of conditions. In this study, a measurement-based model was developed to calibrate an a-Si EPID response to dose for transit dosimetry by comparison with a reference ionization chamber. The ionization chamber reference depth and the required additional buildup thickness for electronic portal imaging devices (EPID) transit dosimetry were determined. The combined effects of changes in radiation field size, phantom thickness, and the off-axis distance on EPID transit dosimetry were characterized. The effect of scattered radiation on out-of-field response was investigated for different field sizes and phantom thicknesses by evaluation of the differences in image profiles and in-water measured profiles. An algorithm was developed to automatically apply these corrections to EPID images based on the user-specified field size and phantom thickness. The average phantom thickness and an effective field size were used for IMRT fields, and images were acquired in cine mode in the presence of an anthropomorphic phantom. The effective field size was defined as the percentage of the jaw-defined field that was involved during the delivery. Nine head and neck dynamic IMRT fields were tested by comparison with a MatriXX two-dimensional array dosimeter using the Gamma (3 %, 3 mm) evaluation. A depth of 1.5 cm was selected as the ionization chamber reference depth. An additional 2.2 mm of copper buildup was added to the EPID. Comparison of EPID and MatriXX dose images for the tested fields showed that using a 10 % threshold, the average number of points with Gamma index <1 was 96.5 %. The agreement in the out-of field area was shown by selection of a 2 % threshold which on average resulted in 94.8 % of points with a Gamma index <1. The suggested method is less complicated than previously reported techniques and can be used for all a-Si EPIDs regardless of the manufacturer.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
¥17,985 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price includes VAT (Japan)

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7

Similar content being viewed by others

References

  1. Antonuk LE (2002) Electronic portal imaging devices: a review and historical perspective of contemporary technologies and research. Phys Med Biol 47:R31–R65

    Article  PubMed  Google Scholar 

  2. Bailey DW, Kumaraswamy L, Podgorsak MB (2009) An effective correction algorithm for off-axis portal dosimetry errors. Med Phys 36(9):4089–4094

    Article  PubMed  Google Scholar 

  3. Berry SL, Polvorosa CS, Wuu C (2010) A field size specific backscatter correction algorithm for accurate EPID dosimetry. Med Phys 37(6):2425–2435

    Article  PubMed  Google Scholar 

  4. Chen J, Chuang CF, Morin O, Aubin M, Pouliot J (2006) Calibration of an amorphous silicon flat panel portal imager for exit beam dosimetry. Med Phys 33(3):584–594

    Article  PubMed  Google Scholar 

  5. Chen J, Moran JA, Roberts DA, El-Mohri Y, Antonuk LE, Fraass BA (2007) Performance of a direct-detection active matrix flat panel dosimeter (AMFPD) for IMRT measurements. Med Phys 34(12):4911–4922

    Article  PubMed  Google Scholar 

  6. Childress NL, Dong L, Rosen II (2002) Rapid radiographic film calibration for IMRT verification using automated MLC fields. Med Phys 29(10):2384–2390

    Article  PubMed  Google Scholar 

  7. Chung H, Li J, Samant S (2011) Feasibility of using two-dimensional array dosimeter for in vivo dose reconstruction via transit dosimetry. J Appl Clin Med Phys 12(3):90–111

    Google Scholar 

  8. Chytyk K, McCurdy BM (2009) Comprehensive fluence model for absolute portal dose image prediction. Med Phys 36(4):1389–1398

    Article  CAS  PubMed  Google Scholar 

  9. Greer PG (2005) Correction of pixel sensitivity variation and off-axis response for amorphous silicon EPID dosimetry. Med Phys 32(12):3558–3568

    Article  PubMed  Google Scholar 

  10. Greer PG, Popescu CC (2003) Dosimetric properties of an amorphous silicon electronic portal imaging device for verification of dynamic intensity modulated radiation therapy. Med Phys 30:1618–1627

    Article  PubMed  Google Scholar 

  11. Greer P, Vial P (2011) EPID Dosimetry. AIP Conf Proc 1345:129–144

    Article  Google Scholar 

  12. Grein EE, Lee R, Luchka K (2002) An investigation of a new amorphous silicon electronic portal imaging device for transit dosimetry. Med Phys 29(10):2262–2268

    Article  CAS  PubMed  Google Scholar 

  13. Han Z, Ng SK, Bhagwat MS, Lyatskaya Y, Zygmanski P (2010) Evaluation of MatriXX for IMRT and VMAT dose verifications in peripheral dose regions. Med Phys 37(7):3704–3714

    Article  PubMed  Google Scholar 

  14. Hansen VN, Evans PM, Swindell W (1996) The application of transit dosimetry to precision radiotherapy. Med Phys 23(5):713–721

    Article  CAS  PubMed  Google Scholar 

  15. Herman MG, Balter JM, Jaffray DA, McGee KP, Munro P, Shalev S, Van Herk M, Wong JW (2001) Clinical use of electronic portal imaging: report of AAPM radiation therapy committee task group 58. AAPM Refresher Course, Salt Lake City

    Google Scholar 

  16. Kavuma A, Glegg M, Currie G, Elliot A (2008) Assessment of dosimetrical performance in 11 Varian a-Si500 electronic portal imaging devices. Phys Med Biol 53:6893–6909

    Article  PubMed  Google Scholar 

  17. Li JG, Yan G, Liu C (2009) Comparison of two commercial detector arrays for IMRT quality assurance. J Appl Clin Med Phys 10(2):62–74

    Article  Google Scholar 

  18. Low AD, Harms WB, Mutic S, Purdy JA (1998) A technique for the quantitative evaluation of dose distributions. Med Phys 25(5):656–661

    Article  CAS  PubMed  Google Scholar 

  19. Low DA, Moran JM, Dempsey JF, Dong L, Oldham M (2011) Dosimetry tools and techniques for IMRT. Med Phys 38(3):1313–1338

    Article  PubMed  Google Scholar 

  20. Mans A, Wendling M, McDermott LN, Sonke JJ, Tielenburg R, Vijlbrief R, Mijnheer B, van Herk M, Stroom JC (2010) Catching errors with in vivo EPID dosimetry. Med Phys 37(6):2638–2644

    Article  CAS  PubMed  Google Scholar 

  21. Mans A, Remeijer P, Olaciregui-Ruiz I, Wendling M, Sonke JJ, Minjheer B, van Herk M, Stroom JC (2010) 3D Dosimetric verification of volumetric-modulated arc therapy by portal dosimetry. Radiother Oncol 94:181–187

    Article  PubMed  Google Scholar 

  22. McCurdy BM, Greer PB (2009) Dosimetric properties of an amorphous-silicon EPID used in continuous acquisition mode for application to dynamic and arc IMRT. Med Phys 36(7):3028–3039

    Article  CAS  PubMed  Google Scholar 

  23. McCurdy BMC, Luchka KB, Pistorius S (2001) Dosimetric investigation and portal dose image prediction using an amorphous silicon electronic portal imaging device. Med Phys 28:911–924

    Article  CAS  PubMed  Google Scholar 

  24. McDermott LN, Louwe RJW, Sonke JJ, van Herk MB, Mijnheer BJ (2004) Dose-response and ghosting effects of an amorphous silicon electronic portal imaging device. Med Phys 31(2):285–295

    Article  CAS  PubMed  Google Scholar 

  25. McDermott LN, Wendling M, Snoke JJ, van Herk MB, Mijnheer BJ (2007) Replacing pre-treatment verification with in vivo EPID dosimetry for prostate IMRT. Int J Radiat Oncol Biol Phys 67:1568–1577

    Article  PubMed  Google Scholar 

  26. McNutt TR, Mackie TR, Reckwerdt P, Papanikolaou N, Paliwal BR (1996) Calculation of portal dose using the convolution/superposition method. Med Phys 23:527–535

    Article  CAS  PubMed  Google Scholar 

  27. Nijsten SMJJG, van Elmpt WJC, Jacobs M, Minjheer BJ, Dekker ALAJ, Lambin P, Minken AWH (2007) A global calibration model for a-Si EPIDs used for transit dosimetry. Med Phys 34(10):3872–3880

    Article  CAS  PubMed  Google Scholar 

  28. Olaciregui-Ruiz I, Rozendaal R, Mijnheer B, van Herk M, Mans A (2013) Automatic in vivo portal dosimetry of all treatments. Phys Med Biol 58:8253–8264

    Article  CAS  PubMed  Google Scholar 

  29. Parent L, Fielding AL, Dance DR, Seco J, Evans PM (2007) Amorphous silicon EPID calibration for dosimetric applications: comparison of a method based on Monte Carlo prediction of response with existing techniques. Phys Med Biol 52:3351–3368

    Article  CAS  PubMed  Google Scholar 

  30. Partridge M, Hesse BM, Müller L (2002) A performance comparison of direct- and indirect- detection flat panel imagers. Nucl Instrum Methods Phys Res A 484:351–363

    Article  CAS  Google Scholar 

  31. Piermattei A, Fidanzio A, Azario L et al (2009) In patient dose reconstruction using a cine acquisition for dynamic arc radiation therapy. Med Biol Eng Comput 47:425–433

    Article  PubMed  Google Scholar 

  32. Roberson PL, Moran JM, Kulasekere R (2008) Radiographic film dosimetry for IMRT fields in the nearsurface buildup region. J Appl Clin Med Phys 9(4):87–97

    Article  Google Scholar 

  33. Rowshanfarzad P, McCurdy BMC, Sabet M, Lee C, O’Connor DJ, Greer PB (2010) Measurement and modeling of the effect of support arm backscatter on dosimetry with a Varian EPID. Med Phys 37(5):2269–2278

    Article  PubMed  Google Scholar 

  34. Sabet M, Menk FW, Greer PB (2010) Evaluation of an a-Si EPID in direct detection configuration as a water equivalent dosimeter for transit dosimetry. Med Phys 37:1459–1467

    Article  CAS  PubMed  Google Scholar 

  35. Sabet M, Rowshanfarzad P, Vial P, Menk FW, Greer PB (2012) Transit dosimetry in IMRT with an a-Si EPID in direct detection configuration. Phys Med Biol 57:N259–N306

    Article  Google Scholar 

  36. Sharma DS, Mhatre V, Heigrujam M, Talapatra K, Mallik S (2010) Portal dosimetry for pretreatment verification of IMRT plan: a comparison with 2D ion chamber array. J Appl Clin Med Phys 11(4):238–248

    Google Scholar 

  37. Siebers JV, Kim JO, Ko L, Keall PJ (2004) Monte Carlo computation of dosimetric amorphous silicon electronic portal images. Med Phys 31:2135–2146

    Article  PubMed  Google Scholar 

  38. Steciw S, Warkentin B, Rathee S, Fallone BG (2005) Three-dimensional IMRT verification with a flat-panel EPID. Med Phys 32:600–612

    Article  CAS  PubMed  Google Scholar 

  39. Talamonti C, Casati M, Bucciolini M (2006) Pretreatment verification of IMRT absolute dose distributions using a commercial a-Si EPID. Med Phys 33:4367–4378

    Article  CAS  PubMed  Google Scholar 

  40. Tyner E, McClean B, McCavana P, Wetterstedt S (2009) Experimental investigation of the response of an a-Si EPID to an unflattened photon beam from an Elekta Precise linear accelerator. Med Phys 36(4):1318–1329

    Article  PubMed  Google Scholar 

  41. Van Elmpt W, McDermott L, Nijsten S, Wendling M, Lambin P, Mijnheer B (2008) A literature review of electronic portal imaging for radiotherapy dosimetry. Radiother Oncol 88:289–309

    Article  PubMed  Google Scholar 

  42. Vial P, Greer PB, Oliver L, Baldock C (2008) Initial evaluation of a commercial EPID modified to a novel direct-detection configuration for radiotherapy dosimetry. Med Phys 35(10):4362–4374

    Article  PubMed  Google Scholar 

  43. Wendling M, Louwe RJ, McDermott LN, Sonke JJ, van Herk M, Mijnheer BJ (2006) Accurate two dimensional IMRT verification using a back projection EPID dosimetry method. Med Phys 33:259–273

    Article  PubMed  Google Scholar 

  44. Winkler P, Hefner A, Georg D (2005) Dose-response characteristics of an amorphous silicon EPID. Med Phys 32(10):3095–3105

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Mahsheed Sabet.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sabet, M., Rowshanfarzad, P., Menk, F.W. et al. Transit dosimetry in dynamic IMRT with an a-Si EPID. Med Biol Eng Comput 52, 579–588 (2014). https://doi.org/10.1007/s11517-014-1161-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11517-014-1161-y

Keywords

Navigation