Abstract
Analysis of pulmonary artery or vein tree has utmost importance in the study and clinical diagnosis of Chronic Obstructive Pulmonary Diseases (COPD). Due to difficulty in acquiring real life patient data and highly complex structure of artery/vein tree, design of imitated/approximate digital pulmonary phantoms for experimental purposes is an active research area. In this work, we discuss theory and methods of designing 3-D mathematical phantoms based on real pulmonary data using a custom made Graphical User Interface (GUI). These approximate phantoms are made using 3-D spheres as the basic unit which are placed in 3-D space using cubic Bezier curves. Results and design steps are explained using appropriate 3-D rendering of digital phantoms developed by our GUI.
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References
Singhal, S., Henderson, R., Horsfield, K., Harding, K., Cumming, G.: Morphometry of the human pulmonary arterial tree. Circ. Res. 33, 190–197 (1973)
Murphy, T.F., Sethi, S.: Chronic obstructive pulmonary disease. Drugs Aging 19, 761–775 (2002)
Fletcher, M., et al.: COPD uncovered: an international survey on the impact of chronic obstructive pulmonary disease [COPD] on a working age population. BMC Public Health 11, 1–13 (2011)
Gurney, J.W., et al.: Regional distribution of emphysema: correlation of high-resolution CT with pulmonary function tests in unselected smokers. Radiology 183, 457–463 (1992)
Das, N., Rakshit, P., Nasipuri, M., Basu, S.: 3-D digital flows in cerebrovascular phantoms. In: 9th International Conference on Pattern Recognition, ICAPR 2017, ISI, Bangalore (2011)
Gao, Z., Grout, R.W., Holtze, C., Hoffman, E.A., Saha, P.: A new paradigm of interactive artery/vein separation in noncontrast pulmonary CT imaging using multiscale topomorphologic opening. IEEE Trans. Biomed. Eng. 59, 3016–3027 (2012)
Cai, Z., Bai, E.: A Dynamic Arterial Tree Phantom for studies of bolus chasing CT Angiography Robert McCabe CIRS Tissue Simulation and Phantom Technology. Ge Wang Madhavan Lakshmi Raghavan and Jarin Kratzberg 4, 88–100 (2010)
Saha, P.K., Gao, Z., Alford, S.K., Sonka, M., Hoffman, E.A.: Topomorphologic separation of fused isointensity objects via multiscale opening: separating arteries and veins in 3-D pulmonary CT. IEEE Trans. Med. Imaging 29, 840–851 (2010)
Saha, P.K., Basu, S., Hoffman, E.A.: Multiscale opening of conjoined fuzzy objects: theory and applications. IEEE Trans. Fuzzy Syst. 24, 1121–1133 (2016)
Brunette, J., Mongrain, R., Ranga, A., Tardif, J.-C.: An atherosclerotic coronary artery phantom for particle image velocimetry. Proc. Can. Eng. Educ. Assoc. 2(2) (2011)
Le Floc’h, S., Cloutier, G., Finet, G., Tracqui, P., Pettigrew, R.I., Ohayon, J.: On the potential of a new IVUS elasticity modulus imaging approach for detecting vulnerable atherosclerotic coronary plaques: in vitro vessel phantom study. Phys. Med. Biol. 55, 5701–5721 (2010)
Hansen, H.H.G., Lopata, R.G.P., De Korte, C.L.: Noninvasive carotid strain imaging using angular compounding at large beam steered angles: validation in vessel phantoms. IEEE Trans. Med. Imaging 28, 872–880 (2009)
De Santis, G., De Beule, M., Van Canneyt, K., Segers, P., Verdonck, P., Verhegghe, B.: Full-hexahedral structured meshing for image-based computational vascular modeling. Med. Eng. Phys. 33, 1318–1325 (2011)
Piccinelli, M., Veneziani, A., Steinman, D.A., Remuzzi, A., Antiga, L.: A framework for geometric analysis of vascular structures: application to cerebral aneurysms. IEEE Trans. Med. Imaging 28, 1141–1155 (2009)
Antiga, L., Piccinelli, M., Botti, L., Ene-Iordache, B., Remuzzi, A., Steinman, D.A.: An image-based modeling framework for patient-specific computational hemodynamics. Med. Biol. Eng. Comput. 46, 1097–1112 (2008)
Zhu, H., Ding, Z., Piana, R.N., Gehrig, T.R., Friedman, M.H.: Cataloguing the geometry of the human coronary arteries: a potential tool for predicting risk of coronary artery disease. Int. J. Cardiol. 135, 43–52 (2009)
Banerjee, A., Dey, S., Parui, S., Nasipuri, M., Basu, S.: Design of 3-D phantoms for human carotid vasculature. In: Proceedings of the 2013 3rd International Conference on Advances in Computing and Communications, ICACC 2013, pp. 347–350 (2013)
Banerjee, A., Dey, S., Parui, S., Nasipuri, M., Basu, S.: Synthetic reconstruction of human carotid vasculature using a 2-D/3-D interface. In: ICACCI, pp. 60–65 (2013)
Borgefors, G.: Distance transformations in digital images. Comput. Vis. Graph. Image Process. 34, 344–371 (1986)
Borgefors, G.: Distance transformations in arbitrary dimensions. Comput. Vis. Graph. Image Process. 27, 321–345 (1984)
Danielsson, P.E.: Euclidean distance mapping. Comput. Graph. Image Process. 14, 227–248 (1980)
Cuisenaire, O., Macq, B.: Fast Euclidean distance transformation by propagation using multiple neighborhoods. Comput. Vis. Image Underst. 76, 163–172 (1999)
Abrahamsen, A.: Cubic Bézier curves. In: Control, pp. 1–4 (2000)
itk-SNAP Homepage. http://www.itksnap.org/pmwiki/pmwiki.php. Accessed 07 Apr 2018
Yushkevich, P.A., et al.: User-guided 3D active contour segmentation of anatomical structures: significantly improved efficiency and reliability. Neuroimage 31, 1116–1128 (2006)
Qt Homepage. https://www.qt.io. Accessed 03 Apr 2018
Acknowledgement
This project is partially supported by the CMATER research laboratory of the Computer Science and Engineering Department, Jadavpur University, India, DST PURSE-II and UPE-II project and Research Award (F.30-31/2016(SA-II)) from UGC, Government of India and CSIR-HRDG, Government of India.
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De, A., Das, N., Sarkar, R., Saha, P.K., Basu, S. (2019). Design of Synthetic 3-D Pulmonary Phantoms Using 2-D Graphical User Interface. In: Mandal, J., Mukhopadhyay, S., Dutta, P., Dasgupta, K. (eds) Computational Intelligence, Communications, and Business Analytics. CICBA 2018. Communications in Computer and Information Science, vol 1030. Springer, Singapore. https://doi.org/10.1007/978-981-13-8578-0_17
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