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Denoising Intra-voxel Axon Fiber Orientations by Means of ECQMMF Method

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MICAI 2009: Advances in Artificial Intelligence (MICAI 2009)

Part of the book series: Lecture Notes in Computer Science ((LNAI,volume 5845))

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Abstract

Diffusion weighted magnetic resonance imaging is widely used in the study of the structure of the fiber pathways in brain white matter. In this work we present a new method for denoising intra–voxel axon fiber tracks. In order to improve local (voxelwise) estimations, we use the general–purpose segmentation method called Entropy–Controlled Quadratic Markov Measure Field Models. Our proposal is capable of spatially–regularize multiple axon fiber orientations (intra-voxel orientations). In order to provide the best as possible local axon orientations to our spatial regularization procedure, we evaluate two optimization methods for fitting a Diffusion Basis Function model. We present qualitative results on real human Diffusion Weighted MRI data where the ground–truth is not available, and we quantitatively validate our results by synthetic experiments.

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Author information

Authors and Affiliations

  1. Facultad de Matematicas, Valenciana, Universidad de Guanajuato, Guanajuato, Gto., Mexico, C.P. 36000

    Alonso Ramirez-Manzanares

  2. CIMAT A.C., Callejon Jalisco S/N, Valenciana, Guanajuato, Gto, Mexico, C.P. 36000

    Mariano Rivera

  3. PICSL, Department of Radiology, University of Pennsylvania, 3600 Market Street, Suite 370, PA, 19104, USA

    James C. Gee

Authors
  1. Alonso Ramirez-Manzanares
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  2. Mariano Rivera
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  3. James C. Gee
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Editor information

Editors and Affiliations

  1. Centro de Investigación en Matemáticas, AC. (CIMAT), Area de Computación, Calle Jalisco S/N, Mineral de Valenciana, Guanajuato, CP 36250, Guanajuato, México

    Arturo Hernández Aguirre

  2. Ciencias de la Computación, Tecnológico de Monterrey, Campus Estado de México, Carretera al lago de Guadalupe Km 3,5, Col. Margarita Maza de Juárez, Atizapán de Zaragoza,, CP 52926, Estado de México, México

    Raúl Monroy Borja

  3. Instituto Nacional de Astrofísica, Optica y Electrónica (INAOE), Ciencias Computacionales, Luis Enrique Erro No. 1, Santa María Tonantzintla, CP 72840, Puebla, México

    Carlos Alberto Reyes Garciá

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Ramirez-Manzanares, A., Rivera, M., Gee, J.C. (2009). Denoising Intra-voxel Axon Fiber Orientations by Means of ECQMMF Method. In: Aguirre, A.H., Borja, R.M., Garciá, C.A.R. (eds) MICAI 2009: Advances in Artificial Intelligence. MICAI 2009. Lecture Notes in Computer Science(), vol 5845. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-05258-3_27

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  • DOI: https://doi.org/10.1007/978-3-642-05258-3_27

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-05257-6

  • Online ISBN: 978-3-642-05258-3

  • eBook Packages: Computer ScienceComputer Science (R0)

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