Abstract
Computed tomography (CT) is a widely used non-invasive medical imaging technique for disease diagnosis. The diagnostic accuracy is often affected by image resolution, which can be insufficient in practice. For medical CT images, the through-plane resolution is often worse than the in-plane resolution and there can be overlap between slices, causing difficulties in diagnoses. Self-supervised methods for through-plane resolution enhancement, which train on in-plane images and infer on through-plane images, have shown promise for both CT and MRI imaging. However, existing self-supervised methods either neglect overlap or can only handle specific cases with fixed combinations of resolution and overlap. To address these limitations, we propose a self-supervised method called SR4ZCT. It employs the same off-axis training approach while being capable of handling arbitrary combinations of resolution and overlap. Our method explicitly models the relationship between resolutions and voxel spacings of different planes to accurately simulate training images that match the original through-plane images. We highlight the significance of accurate modeling in self-supervised off-axis training and demonstrate the effectiveness of SR4ZCT using a real-world dataset.
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References
Angelopoulos, C., Scarfe, W.C., Farman, A.G.: A comparison of maxillofacial CBCT and medical CT. Atlas Oral Maxillofac. Surg. Clin. North Am. 20(1), 1–17 (2012)
Brink, J.A.: Technical aspects of helical (spiral) CT. Radiol. Clin. North Am. 33(5), 825–841 (1995)
Coward, J., et al.: Multi-centre analysis of incidental findings on low-resolution CT attenuation correction images. Br. J. Radiol. 87(1042), 20130701 (2014)
Gavrielides, M.A., Zeng, R., Myers, K.J., Sahiner, B., Petrick, N.: Benefit of overlapping reconstruction for improving the quantitative assessment of CT lung nodule volume. Acad. Radiol. 20(2), 173–180 (2013)
Hansen, P.C., Jørgensen, J., Lionheart, W.R.: Computed Tomography: Algorithms, Insight, and Just Enough Theory. SIAM (2021)
He, L., Huang, Y., Ma, Z., Liang, C., Liang, C., Liu, Z.: Effects of contrast-enhancement, reconstruction slice thickness and convolution kernel on the diagnostic performance of radiomics signature in solitary pulmonary nodule. Sci. Rep. 6(1), 34921 (2016)
Honda, O., et al.: Computer-assisted lung nodule volumetry from multi-detector row CT: influence of image reconstruction parameters. Eur. J. Radiol. 62(1), 106–113 (2007)
Iwano, S., et al.: Solitary pulmonary nodules: optimal slice thickness of high-resolution CT in differentiating malignant from benign. Clin. Imaging 28(5), 322–328 (2004)
Kasales, C., et al.: Reconstructed helical CT scans: improvement in z-axis resolution compared with overlapped and nonoverlapped conventional CT scans. AJR Am. J. Roentgenol. 164(5), 1281–1284 (1995)
Kingma, D.P., Ba, J.: Adam: a method for stochastic optimization. In: Bengio, Y., LeCun, Y. (eds.) 3rd International Conference on Learning Representations, ICLR 2015, San Diego, CA, USA, May 7–9, 2015, Conference Track Proceedings (2015). http://arxiv.org/abs/1412.6980
Liu, Q., Zhou, Z., Liu, F., Fang, X., Yu, Y., Wang, Y.: Multi-stream progressive up-sampling network for dense CT image reconstruction. In: Martel, A.L., et al. (eds.) MICCAI 2020. LNCS, vol. 12266, pp. 518–528. Springer, Cham (2020). https://doi.org/10.1007/978-3-030-59725-2_50
McCollough, C.H., et al.: Low-dose CT for the detection and classification of metastatic liver lesions: results of the 2016 low dose CT grand challenge. Med. Phys. 44(10), e339–e352 (2017)
Pelt, D.M., Sethian, J.A.: A mixed-scale dense convolutional neural network for image analysis. Proc. Natl. Acad. Sci. 115(2), 254–259 (2018)
Peng, C., Lin, W.A., Liao, H., Chellappa, R., Zhou, S.K.: Saint: spatially aware interpolation network for medical slice synthesis. In: Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition, pp. 7750–7759 (2020)
Ravenel, J.G., Leue, W.M., Nietert, P.J., Miller, J.V., Taylor, K.K., Silvestri, G.A.: Pulmonary nodule volume: effects of reconstruction parameters on automated measurements-a phantom study. Radiology 247(2), 400–408 (2008)
Simpson, A.L., et al.: A large annotated medical image dataset for the development and evaluation of segmentation algorithms. arXiv preprint arXiv:1902.09063 (2019)
Tsukagoshi, S., Ota, T., Fujii, M., Kazama, M., Okumura, M., Johkoh, T.: Improvement of spatial resolution in the longitudinal direction for isotropic imaging in helical CT. Phys. Med. Biol. 52(3), 791 (2007)
Xie, H., et al.: High through-plane resolution CT imaging with self-supervised deep learning. Phys. Med. Biol. 66(14), 145013 (2021)
Yu, P., Zhang, H., Kang, H., Tang, W., Arnold, C.W., Zhang, R.: RPLHR-CT dataset and transformer baseline for volumetric super-resolution from CT scans. In: Wang, L., Dou, Q., Fletcher, P.T., Speidel, S., Li, S. (eds.) Medical Image Computing and Computer Assisted Intervention – MICCAI 2022. MICCAI 2022. Lecture Notes in Computer Science, vol. 13436, pp. 344–353. Springer, Cham (2022). https://doi.org/10.1007/978-3-031-16446-0_33
Zhao, C., Dewey, B.E., Pham, D.L., Calabresi, P.A., Reich, D.S., Prince, J.L.: Smore: a self-supervised anti-aliasing and super-resolution algorithm for MRI using deep learning. IEEE Trans. Med. Imaging 40(3), 805–817 (2020)
Acknowledgment
This research was financed by the European Union H2020-MSCA-ITN-2020 under grant agreement no. 956172 (xCTing).
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Shi, J., Pelt, D.M., Batenburg, K.J. (2024). SR4ZCT: Self-supervised Through-Plane Resolution Enhancement for CT Images with Arbitrary Resolution and Overlap. In: Cao, X., Xu, X., Rekik, I., Cui, Z., Ouyang, X. (eds) Machine Learning in Medical Imaging. MLMI 2023. Lecture Notes in Computer Science, vol 14348. Springer, Cham. https://doi.org/10.1007/978-3-031-45673-2_6
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