Abstract
Volumetric measurements of fetal structures in MRI are time consuming and error prone and therefore require automatic segmentation. Placenta segmentation and accurate fetal brain segmentation for gyrification assessment are particularly challenging because of the placenta fuzzy boundaries and the fetal brain cortex complex foldings. In this paper, we study the use of the Contour Dice loss for both problems and compare it to other boundary losses and to the combined Dice and Cross-Entropy loss. The loss is computed efficiently for each slice via erosion, dilation and XOR operators. We describe a new formulation of the loss akin to the Contour Dice metric. The combination of the Dice loss and the Contour Dice yielded the best performance for placenta segmentation. For fetal brain segmentation, the best performing loss was the combined Dice with Cross-Entropy loss followed by the Dice with Contour Dice loss, which performed better than other boundary losses.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
Al Arif, S.M.M.R., Knapp, K., Slabaugh, G.: Shape-aware deep convolutional neural network for vertebrae segmentation. In: Glocker, B., Yao, J., Vrtovec, T., Frangi, A., Zheng, G. (eds.) MSKI 2017. LNCS, vol. 10734, pp. 12–24. Springer, Cham (2018). https://doi.org/10.1007/978-3-319-74113-0_2
Alansary, A., et al.: Fast fully automatic segmentation of the human placenta from motion corrupted MRI. In: Ourselin, S., Joskowicz, L., Sabuncu, M.R., Unal, G., Wells, W. (eds.) MICCAI 2016. LNCS, vol. 9901, pp. 589–597. Springer, Cham (2016). https://doi.org/10.1007/978-3-319-46723-8_68
Caliva, F., Iriondo, C., Martinez, A.M., Majumdar, S., Pedoia, V.: Distance map loss penalty term for semantic segmentation. In: International Conference on Medical Imaging with Deep Learning - Extended Abstract Track, pp. 08–10 (2019). https://openreview.net/forum?id=B1eIcvS45V
Dubois, J., et al.: Primary cortical folding in the human newborn: an early marker of later functional development. Brain 131(8), 2028–2041 (2008)
Dubois, J., et al.: The dynamics of cortical folding waves and prematurity-related deviations revealed by spatial and spectral analysis of gyrification. Neuroimage 185, 934–946 (2019)
Dudovitch, G., Link-Sourani, D., Ben Sira, L., Miller, E., Ben Bashat, D., Joskowicz, L.: Deep learning automatic fetal structures segmentation in MRI scans with few annotated datasets. In: Martel, A.L., et al. (eds.) MICCAI 2020. LNCS, vol. 12266, pp. 365–374. Springer, Cham (2020). https://doi.org/10.1007/978-3-030-59725-2_35
Ebner, M., et al.: An automated framework for localization, segmentation and super-resolution reconstruction of fetal brain MRI. Neuroimage 206, 116324 (2020)
Han, M., et al.: Automatic segmentation of human placenta images with U-Net. IEEE Access 7, 180083–180092 (2019)
Hosny, I.A., Elghawabi, H.S.: Ultrafast MRI of the fetus: an increasingly important tool in prenatal diagnosis of congenital anomalies. Magn. Reson. Imaging 28(10), 1431–1439 (2010)
Isensee, F., Jaeger, P.F., Kohl, S.A., Petersen, J., Maier-Hein, K.H.: nnU-Net: a self-configuring method for deep learning-based biomedical image segmentation. Nat. Methods 18(2), 203–211 (2021)
Jurdi, R.E., Petitjean, C., Honeine, P., Cheplygina, V., Abdallah, F.: A surprisingly effective perimeter-based loss for medical image segmentation. In: Medical Imaging with Deep Learning, pp. 158–167. PMLR (2021)
Karimi, D., Salcudean, S.E.: Reducing the Hausdorff distance in medical image segmentation with convolutional neural networks. IEEE Trans. Med. Imaging 39(2), 499–513 (2019)
Kervadec, H., Bouchtiba, J., Desrosiers, C., Granger, E., Dolz, J., Ayed, I.B.: Boundary loss for highly unbalanced segmentation. In: International Conference on Medical Imaging with Deep Learning, pp. 285–296. PMLR (2019)
Kiser, K.J., Barman, A., Stieb, S., Fuller, C.D., Giancardo, L.: Novel autosegmentation spatial similarity metrics capture the time required to correct segmentations better than traditional metrics in a thoracic cavity segmentation workflow. J. Digit. Imaging 34(3), 541–553 (2021)
Kodym, O., Španěl, M., Herout, A.: Segmentation of head and neck organs at risk using CNN with batch dice loss. In: Brox, T., Bruhn, A., Fritz, M. (eds.) GCPR 2018. LNCS, vol. 11269, pp. 105–114. Springer, Cham (2019). https://doi.org/10.1007/978-3-030-12939-2_8
Ma, J., et al.: Loss odyssey in medical image segmentation. Med. Image Anal. 71, 102035 (2021)
Nikolov, S., et al.: Deep learning to achieve clinically applicable segmentation of head and neck anatomy for radiotherapy. arXiv preprint arXiv:1809.04430 (2018)
Payette, K., et al.: Fetal brain tissue annotation and segmentation challenge results. arXiv preprint arXiv:2204.09573 (2022)
Pietsch, M., et al.: APPLAUSE: automatic prediction of placental health via U-Net segmentation and statistical evaluation. Med. Image Anal. 72, 102145 (2021)
Quah, B., et al.: Comparison of pure deep learning approaches for placental extraction from dynamic functional MRI sequences between 19 and 37 gestational weeks. In: Proceedings of International Society for Magnetic Resonance in Medicine (2021)
Reddy, U.M., Filly, R.A., Copel, J.A.: Prenatal imaging: ultrasonography and magnetic resonance imaging. Obstet. Gynecol. 112(1), 145 (2008)
Rutherford, M., et al.: MR imaging methods for assessing fetal brain development. Dev. Neurobiol. 68(6), 700–711 (2008)
Salavati, N., et al.: The possible role of placental morphometry in the detection of fetal growth restriction. Front. Physiol. 9, 1884 (2019)
Salehi, S.S.M., et al.: Real-time automatic fetal brain extraction in fetal MRI by deep learning. In: 2018 IEEE 15th International Symposium on Biomedical Imaging (ISBI 2018), pp. 720–724. IEEE (2018)
Specktor-Fadida, B., et al.: A bootstrap self-training method for sequence transfer: state-of-the-art placenta segmentation in fetal MRI. In: Sudre, C.H., et al. (eds.) UNSURE/PIPPI -2021. LNCS, vol. 12959, pp. 189–199. Springer, Cham (2021). https://doi.org/10.1007/978-3-030-87735-4_18
Torrents-Barrena, J., et al.: Fully automatic 3D reconstruction of the placenta and its peripheral vasculature in intrauterine fetal MRI. Med. Image Anal. 54, 263–279 (2019)
Torrents-Barrena, J., et al.: Segmentation and classification in MRI and us fetal imaging: recent trends and future prospects. Med. Image Anal. 51, 61–88 (2019)
Yang, S., Kweon, J., Kim, Y.H.: Major vessel segmentation on X-ray coronary angiography using deep networks with a novel penalty loss function. In: International Conference on Medical Imaging with Deep Learning-Extended Abstract Track (2019)
Acknowledgement
This research was supported in part by Kamin Grants 72061 and 72126 from the Israel Innovation Authority.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG
About this paper
Cite this paper
Specktor-Fadida, B., Yehuda, B., Link-Sourani, D., Ben-Sira, L., Ben-Bashat, D., Joskowicz, L. (2023). Contour Dice Loss for Structures with Fuzzy and Complex Boundaries in Fetal MRI. In: Karlinsky, L., Michaeli, T., Nishino, K. (eds) Computer Vision – ECCV 2022 Workshops. ECCV 2022. Lecture Notes in Computer Science, vol 13803. Springer, Cham. https://doi.org/10.1007/978-3-031-25066-8_19
Download citation
DOI: https://doi.org/10.1007/978-3-031-25066-8_19
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-031-25065-1
Online ISBN: 978-3-031-25066-8
eBook Packages: Computer ScienceComputer Science (R0)