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Mortality Risk Evaluation: A Proposal for Intensive Care Units Patients Exploring Machine Learning Methods

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Intelligent Systems (BRACIS 2022)

Abstract

The high availability of clinical data and a heterogeneous and complex patient population makes Intensive Care Units (ICUs) environments opportune for developing a system that analyzes large amounts of raw data, which human specialists can neglect. Quantifying a patient’s condition to support the definition and adjustment of clinical treatment and predict future outcomes is a significant research problem in intensive care. This work’s main objective is to conceive an approach to predicting ICUs mortality risk. Therefore, the designed approach is a binary classification task that aims to predict whether patients will die or survive during their ICU stay. A cohort of 17,734 patients was used from the MIMIC-III database, considering 10 input predictor variables and 8 Machine Learning methods. Sensitivity, specificity, F1 score, AUC, and ROC curve are used to compare different models of mortality risk prediction in a 48-h window of data acquisition. The best performance was achieved by the Gradient Boosting Machine (GBM) method, which obtained 0,843 (±0,015) of AUC and 0,503 (±0,048) for the F1 score. The approach conceived enables the generation of robust models capable of detecting hidden patterns and having greater power of discrimination in classifications. The results are promising and, in some cases, superior to those obtained by other proposals identified in the literature review.

Supported by CAPES, CNPq and IF-RS.

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Acknowledgments

The present work was supported by Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brazil (CAPES) - Financing Code 001 and Instituto Federal do Rio Grande do Sul (IF-RS).

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Correspondence to Alexandre Renato Rodrigues de Souza .

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de Souza, A.R.R. et al. (2022). Mortality Risk Evaluation: A Proposal for Intensive Care Units Patients Exploring Machine Learning Methods. In: Xavier-Junior, J.C., Rios, R.A. (eds) Intelligent Systems. BRACIS 2022. Lecture Notes in Computer Science(), vol 13653. Springer, Cham. https://doi.org/10.1007/978-3-031-21686-2_1

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  • DOI: https://doi.org/10.1007/978-3-031-21686-2_1

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