Chronic relapsing myalgia (? Post viral): clinical, histological, and biochemical studies
- PMID: 3864422
- DOI: 10.1111/j.1445-5994.1985.tb04042.x
Chronic relapsing myalgia (? Post viral): clinical, histological, and biochemical studies
Abstract
Two patients with persistent myalgia characterised by onset after an ill-defined systemic illness, marked fluctuations in the severity of the symptoms, and normal neuromuscular examination with the exception of variable muscle tenderness on deep palpation, may have a forme fruste of myalgic encephalomyelitis. Differentiation from psychogenic muscle pain is important in management. Muscle histology revealed non-specific Type II fibre atrophy. Mitochondrial respiration was assayed polarographically in intact organelles in vitro and revealed a mild depression of State 3 respiration rates with Site I and Site II substrates.
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