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. 2020 Jan 22;72(1):6.
doi: 10.1186/s43044-020-0041-z.

Role of deformation imaging in left ventricular non-compaction and hypertrophic cardiomyopathy: an Indian perspective

A J Ashwal  1 , Sudhakar Rao Mugula  2 , Jyothi Samanth  3 , Ganesh Paramasivam  1 , Krishnananda Nayak  3 , R Padmakumar  1
Affiliations

Role of deformation imaging in left ventricular non-compaction and hypertrophic cardiomyopathy: an Indian perspective

A J Ashwal et al. Egypt Heart J. .

Abstract

Background: Speckle tracking echocardiography (STE) has emerged as a novel feasible tool for the assessment of left ventricular rotational parameters. Since hypertrophic cardiomyopathy(HCM) shares morphologic features with left ventricular non-compaction (LVNC), we used this imaging modality to compare rotational mechanics between these two entities.

Results: We compared global and regional LV function and rotational mechanics between LVNC, HCM, and healthy subjects using STE. Longitudinal strain and torsion were obtained from echocardiographic images from parasternal short axis as well as standard LV apical views. Twelve patients with LVNC [mean age 46.12 ± 14.66 years; median 47.5 IQR (39.25-58.5) years] were compared with 18 HCM patients [mean age 49.48± 17.22 years; median 56 IQR (33-65) years] and 18 healthy subjects [mean age: 51.50± 12.51 years; median 51(45.75-58) years]. LVNC group showed a significantly reduced longitudinal strain at the apical region compared to HCM group (- 12.18 ± 6.25 vs - 18.37 ± 3.67; P < 0.05). Rigid body rotation(RBR) was found in 50% of patients whereas the other half had a normal rotation at the apex and the base. Among the patients with RBR, all patients had a uniform counterclockwise rotation.

Conclusion: Longitudinal strain was impaired in both the forms of cardiomyopathy; however, LVNC showed a more significant reduction in the apical region compared to patients with HCM suggesting a development abnormality in these regions. A reduction in left ventricular torsion was specifically noted among patients with LVNC with a uniform anticlockwise rotation of LV base and apex.

Keywords: Speckle tracking; non-compaction; rotation mechanics; strain.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Speckle tracking echocardiography (Echo Pac software) in patients with LVNC showing net basal rotation (purple color) and net apical rotation (green color) in the same counter-clockwise direction. Net torsion is displayed in white color
Fig. 2
Fig. 2
Speckle tracking echocardiography (Echo Pac software) in patients with HCM showing net basal rotation (purple color) in counter-clockwise direction and net apical rotation (green color) in clockwise direction. Net torsion is displayed in white color
Fig. 3
Fig. 3
Speckle tracking echocardiography (Echo Pac software) in normal subjects showing net basal rotation (purple color) in counter-clockwise direction and net apical rotation (green color) in clockwise direction. Net torsion is displayed in white color
See this image and copyright information in PMC

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