Diagnostic performances of shear wave elastography: which parameter to use in differential diagnosis of solid breast masses? - PubMed Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Jul;23(7):1803-11.
doi: 10.1007/s00330-013-2782-5. Epub 2013 Feb 20.

Diagnostic performances of shear wave elastography: which parameter to use in differential diagnosis of solid breast masses?

Eun Jung Lee  1 , Hae Kyoung Jung, Kyung Hee Ko, Jong Tae Lee, Jung Hyun Yoon
Affiliations

Diagnostic performances of shear wave elastography: which parameter to use in differential diagnosis of solid breast masses?

Eun Jung Lee et al. Eur Radiol. 2013 Jul.

Abstract

Objective: To evaluate which shear wave elastography (SWE) parameter proves most accurate in the differential diagnosis of solid breast masses.

Methods: One hundred and fifty-six breast lesions in 139 consecutive women (mean age: 43.54 ± 9.94 years, range 21-88 years), who had been scheduled for ultrasound-guided breast biopsy, were included. Conventional ultrasound and SWE were performed in all women before biopsy procedures. Ultrasound BI-RADS final assessment and SWE parameters were recorded. Diagnostic performance of each SWE parameter was calculated and compared with those obtained when applying cut-off values of previously published data. Performance of conventional ultrasound and ultrasound combined with each parameter was also compared.

Results: Of the 156 breast masses, 120 (76.9 %) were benign and 36 (23.1 %) malignant. Maximum stiffness (Emax) with a cut-off of 82.3 kPa had the highest area under the receiver operating characteristics curve (Az) value compared with other SWE parameters, 0.860 (sensitivity 88.9 %, specificity 77.5 %, accuracy 80.1 %). Az values of conventional ultrasound combined with each SWE parameter showed lower (but not significantly) values than with conventional ultrasound alone.

Conclusions: Maximum stiffness (82.3 kPa) provided the best diagnostic performance. However the overall diagnostic performance of ultrasound plus SWE was not significantly better than that of conventional ultrasound alone.

Key points: • SWE offers new information over and above conventional breast ultrasound • Various SWE parameters were explored regarding distinction between benign and malignant lesions • An elasticity of 82.3 kPa appears optimal in differentiating solid breast masses • However, ultrasound plus SWE was not significantly better than conventional ultrasound alone.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Eur Radiol. 2013 Apr;23(4):1006-14 - PubMed
    1. Eur J Radiol. 2013 Mar;82(3):427-34 - PubMed
    1. Eur Radiol. 2012 May;22(5):1023-32 - PubMed
    1. AJR Am J Roentgenol. 2008 Jan;190(1):202-7 - PubMed
    1. Acta Radiol. 2011 Dec 1;52(10):1069-75 - PubMed

LinkOut - more resources