Road accidents are one of the major causes of loss of life, injuries and damage of property. The aim of this paper is to assess the overall health status (physical and psychological) of road accident victims and to propose a Health IT system to managing the assessment procedure. A prospective observational study was conducted among 474 people attended to the emergency department, after a road accident. 30% of the participants were 18–28 years old. After the road accident, most patients (67.1%) did not develop depression and 3 and 6 months after the accident, depression levels were higher. In contrast, the patients’ QoL showed improvement over time. As road accidents seems to be a high risk incidents that can affect the health status of people, an Health IT system is suggested to contribute on the management of the assessment of the patients’ health status.