Background: Arden Syntax is an international standard for medical knowledge representation and processing. The openEHR Foundation publishes specifications for the creation of electronic health records based on interoperable data models.

Objectives: To perform a feasibility study showing how Arden Syntax medical logic modules (MLMs) can access openEHR data.

Methods: Medexter's ArdenSuite was applied as an implementation of an Arden-Syntax-based clinical decision support framework, and Marand's EhrScape as an implementation of an openEHR system, for the purpose of data exchange. To assess their interoperability, we developed a use case in which ArdenSuite was connected to EhrScape; the purpose was to determine whether a patient suffers from orthostatic hypotension based on data supplied by EhrScape and decision support provided by Arden Syntax MLMs.

Results: An archetype query language request was sent from an MLM to EhrScape, and the results were sent back.

Conclusion: This preliminary study clearly shows that the ArdenSuite's MLMs can communicate with openEHR-based data sources.