Based on a ternary perfect sequence and a binary orthogonal matrix, the Z-periodic complementary sequence (ZPCS) sets over the 8-QAM+ constellation are constructed. The resultant sequences can be used in multi-carriers code division multiple access (MC-CDMA) systems to remove interference and increase the transmission rate. The proposed construction provides flexible choice for parameters so as to meet different requirements in the application. A construction of shift sequence sets is proposed and the number of 8-QAM ZPCS sets is extended by changing the parameters of shift sequences. As a result, more users can be accommodated in the system.