Geometry of the Gene Expression Space of Individual Cells
Fig 5
Mouse and human colon lower crypt cells fall on similar triangles and show a similar distribution within the triangle.
(a) Mouse colon lower crypt cells dataset by [37], plotted on its first 2PCs plane. Inset: PCA explained variance analysis suggest k = 3 vertices and D = 2 dimensions, namely a triangle. (b) Human lower crypt dataset plotted on its first 2PC plane. Inset: explained PCA explained variance analysis. The 24 genes common to the two datasets were used. Arrow indicates projection of the nodal cell archetype on the triangle.