Abstract
Traditional methods of treatment planning and plan evaluation involve the use of generic dose-constraints. We aimed to build a web-based application to generate individualized dose-constraints and plan evaluation against a library of prior approved plan dose-volume histograms (DVH).
A prototype was built for intensity modulated radiation therapy (IMRT) plans for prostate cancer. Using exported DVH files from the Varian and Accuray treatment planning systems, a library of plan DVHs was built by data extraction. Given structure volumes of a patient to be planned, a web based application was built to derive individual dose-constraints of the planning target volume (PTV) and organs-at-risk (OAR) based on achieved doses in a library of prior approved plans with similar anatomical volumes, selected using an interactive dashboard. A second web application was built to compare the achieved DVHs of the newly created plan against a library of plans of similar patients.
These web application prototypes are a proof of principle that simple freely available tools can be built for library based planning and review.
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Data is not available with this manuscript but can be made available on request after IRB permission.
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Code is not available with this manuscript.
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Mallick, I., Saha, S. & Arunsingh, M.A. A Web-based Dose-volume Histogram Dashboard for Library-based Individualized Dose-constraints and Clinical Plan Evaluation. J Med Syst 45, 62 (2021). https://doi.org/10.1007/s10916-021-01740-9
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DOI: https://doi.org/10.1007/s10916-021-01740-9