Abstract
Epileptic seizures seem to result from an abnormal synchronization of different areas of the brain, as if a kind of recruitment occurred from a critical area towards other areas of the brain, until the brain itself can no longer bear the extent of this recruitment and triggers the seizure in order to reset this abnormal condition. In order to catch these recruitment phenomena, a technique based on entropy is introduced to study the synchronization of the electric activity of neuronal sources in the brain and tested over three EEG dataset from patients affected by partial epilepsy. Entropy showed a very steady spatial distribution and appeared linked to the region of seizure onset. Entropy mapping was compared with the standard power mapping that was much less stable and selective. A SOM based spatial clustering of entropy topography showed that the critical electrodes were coupled together long time before the seizure onset.
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References
Im, C.-H., Jung, H.-K., Jung, K.-Y., Lee, S.Y.: Reconstruction of continuous and focalized brain functional source images from electroencephalography. IEEE Trans. on Magnetics 43(4), 1709–1712 (2007)
Im, C.-H., Lee, C., An, K.-O., Jung, H.-K., Jung, K.-Y., Lee, S.Y.: Precise estimation of brain electrical sources using anatomically constrained area source (acas) localization. IEEE Trans. on Magnetics 43(4), 1713–1716 (2007)
Knutsson, E., Hellstrand, E., Schneider, S., Striebel, W.: Multichannel magnetoencephalography for localization of epileptogenic activity in intractable epilepsies. IEEE Trans. on Magnetics 29(6), 3321–3324 (1993)
Sackellares, J.C., Iasemidis, L.D., Gilmore, R.L., Roper, S.N.: Clinical application of computed eeg topography. In: Duffy, F.H. (ed.) Topographic Mapping of Brain Electrical Activity, Boston, Butterworths (1986)
Nuwer, M.R.: Quantitative eegs. Journal of Clinical Neurophysiology 5, 1–86 (1988)
Babiloni, C., Binetti, G., Cassetta, E., Cerboneschi, D., Dal Forno, G., Del Percio, C., Ferreri, F., Ferri, R., Lanuzza, B., Miniussi, C., Oretti, D.V.M., Nobili, F., Pascual-Marqui, R.D., Rodriguez, G., Romani, G., Salinari, S., Tecchio, F., Vitali, P., Zanetti, O., Zappasodi, F., Rossini, P.M.: Mapping distributed sources of cortical rhythms in mild alzheimer’s disease. a multicentric eeg study. NeuroImage 22, 57–67 (2004)
Miyagi, Y., Morioka, T., Fukui, K., Kawamura, T., Hashiguchi, K., Yoshida, F., Shono, T., Sasaki, T.: Spatio-temporal analysis by voltage topography of ictal electroencephalogram on mr surface anatomy scan for the localization of epileptogenic areas. Minim. Invasive Neurosurg. 48(2), 97–100 (1988)
Ebersole, J.S.: Defining epileptic foci: past, present, future. Journal of Clinical Neurophysiology 14, 470–483 (1997)
Scherg, M.: From eeg source localization to source imaging. Acta Neurol. Scand. 152, 29–30 (1994)
Tekgul, H., Bourgeois, B.F., Gauvreau, K., Bergin, A.M.: Electroencephalography in neonatal seizures: comparison of a reduced and a full 10/20 montage. Pediatr. Neurol. 32(3), 155–161 (2005)
Nayak, D., Valentin, A., Alarcon, G., Garcia Seoane, J.J., Brunnhuber, F., Juler, J., Polkey, C.E., Binnie, C.D.: Characteristics of scalp electrical fields associated with deep medial temporal epileptiform discharges. Journal of Clinical Neurophysiology 115(6), 1423–1435 (2004)
Skrandies, W., Dralle, D.: Topography of spectral eeg and late vep components in patients with benign rolandic epilepsy of childhood. J. Neural Transm. 111(2), 223–230 (2004)
Hild II, K.E., Erdogmus, D., Principe, J.C.: On-line minimum mutual information method for time varying blind source separation. In: 3rd International Conference on Independent Component Analysis And Blind Signal Separation, pp. 126–131 (2001)
Delorme, A., Makeig, S.: Eeglab: an open source toolbox for analysis of single-trial eeg dynamics including independent component analysis. Journal of Neuroscience Methods 134, 9–21 (2004)
Kohonen, T.: Self-Organizing Maps. Series in Information Sciences, vol. 30. Springer, Heidelberg (1995)
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Mammone, N., Inuso, G., La Foresta, F., Versaci, M., Morabito, F.C. (2009). Clustering of Entropy Topography in Epileptic Electroencephalography. In: Palmer-Brown, D., Draganova, C., Pimenidis, E., Mouratidis, H. (eds) Engineering Applications of Neural Networks. EANN 2009. Communications in Computer and Information Science, vol 43. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-03969-0_43
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DOI: https://doi.org/10.1007/978-3-642-03969-0_43
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