Abstract
Our study introduces an innovative framework tailored for COVID-19 diagnosis utilizing a vast, meticulously annotated repository of CT scans (each comprising multiple slices). Our framework comprises three key Parts: the segmentation module (based on UNet and optionally incorporating slice removal techniques), the lung extraction module, and the final classification module. The distinctiveness of our approach lies in augmenting the original UNet model with batch normalization, thereby yielding lighter and more precise localization, essential for constructing a comprehensive COVID-19 diagnosis framework. To gauge the efficacy of our framework, we conducted a comparative analysis of other possible approaches. Our novel approach segmenting through UNet architecture, enhanced with Batch Norm, exhibited superior performance over conventional methods and alternative solutions, achieving High similarity coefficient on public data. Furthermore, at the slice level, our framework demonstrated remarkable validation accuracy and at the patient level, our approach outperformed other alternatives, surpassing baseline model. For the final diagnosis decisions, our framework employs a Convolutional Neural Network (CNN). Utilizing the COV19-CT Database, characterized by a vast array of CT scans with diverse slice types and meticulously marked for COVID-19 diagnosis, our framework exhibited enhancements over prior studies and surpassed numerous alternative methods on this dataset.
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References
Verity, R., et al.: Estimates of the severity of COVID-19 disease. MedRxiv, 2020-03 (2020)
https://covid19.who.int/. Accessed 28 Sept 2022
Desai, S.B., Pareek, A., Lungren, M.P.: Deep learning and its role in COVID-19 medical imaging. Intel. Based Med. 3, 100013 (2020)
Mehrtash, A., et al.: Confidence calibration and predictive uncertainty estimation for deep medical image segmentation. IEEE Trans. Med. Imaging 39(12), 3868–3878 (2020)
Siddique, N., et al.: U-Net and its variants for medical image segmentation: a review of theory and applications. IEEE Access 9, 82031–82057 (2021)
Kollias, D., Arsenos, A., Kollias, S.: AI-MIA: COVID-19 detection & severity analysis through medical imaging. arXiv preprint arXiv:2206.04732 (2022)
Kollias, D., Arsenos, A., Soukissian, L., Kollias, S.: MIA-COV19D: COVID-19 detection through 3-D chest CT image analysis. In: Proceedings of the IEEE/CVF International Conference on Computer Vision, pp. 537–544 (2021)
Kollias, D., Arsenos, A., Kollias, S.: AI-enabled analysis of 3-D CT scans for diagnosis of COVID-19 & its severity. In: 2023 IEEE International Conference on Acoustics, Speech, and Signal Processing Workshops (ICASSPW). IEEE (2023)
Kollias, D., et al.: Transparent adaptation in deep medical image diagnosis. In: Heintz, F., Milano, M., O’Sullivan, B. (eds.) TAILOR 2020. LNCS, vol. 12641, pp. 251–267. Springer, Cham (2021). https://doi.org/10.1007/978-3-030-73959-1_22
Kollias, D., Tagaris, A., Stafylopatis, A., Kollias, S., Tagaris, G.: Deep neural architectures for prediction in healthcare. Complex Intell. Syst. 4, 119–131 (2018)
Arsenos, A., et al.: Data-driven covid-19 detection through medical imaging. In: 2023 IEEE International Conference on Acoustics, Speech, and Signal Processing Workshops (ICASSPW). IEEE (2023)
Kollias, D., Arsenos, A., Kollias, S.: AI-MIA: COVID-19 detection and severity analysis through medical imaging. In: Karlinsky, L., Michaeli, T., Nishino, K. (eds.) ECCV 2022. LNCS, Part VII, vol. 13807, pp. 677–690. Springer, Cham (2023). https://doi.org/10.1007/978-3-031-25082-8_46
Fan, D.-P., et al.: Inf-Net: automatic COVID-19 lung infection segmentation from CT images. IEEE Trans. Med. Imaging 39(8), 2626–2637 (2020)
Zhao, X., et al.: D2a U-Net: automatic segmentation of COVID-19 lesions from CT slices with dilated convolution and dual attention mechanism. arXiv preprint arXiv:2102.05210 (2021)
Chen, X., Yao, L., Zhang, Y.: Residual attention u-net for automated multi-class segmentation of COVID-19 chest CT images. arXiv preprint arXiv:2004.05645 (2020)
Zhang, L., Wen, Y.: A transformer-based framework for automatic COVID19 diagnosis in chest CTs. In: Proceedings of the IEEE/CVF International Conference on Computer Vision (2021)
Tan, W., Liu, J.: A 3D CNN network with BERT for automatic COVID-19 diagnosis from CT-scan images. In: Proceedings of the IEEE/CVF International Conference on Computer Vision (2021)
Oktay, O., et al.: Attention U-Net: learning where to look for the pancreas. arXiv preprint arXiv:1804.03999 (2018)
Pham, D.L., Chenyang, X., Prince, J.L.: A survey of current methods in medical image segmentation. Annu. Rev. Biomed. Eng. 2(3), 315–337 (2000)
Morani, K., Unay, D.: Deep learning based automated COVID-19 classification from computed tomography images. arXiv preprint arXiv:2111.11191 (2021)
Zou, K.H., et al.: Statistical validation of image segmentation quality based on a spatial overlap index. Acad. Radiol. 11(2), 178–89 (2004). https://doi.org/10.1016/s1076-6332(03)00671-8
Opitz, J., Burst, S.: Macro F1 and macro F1. arXiv preprint arXiv:1911.03347 (2019)
Morani, K., et al.: COVID-19 detection using transfer learning approach from computed tomography images (2022)
Morani, K.: COVID-19 detection using segmentation, region extraction and classification pipeline. arXiv preprint arXiv:2210.02992 (2022)
Acknowledgment
The authors acknowledge the work of the medical staff and individuals involved in annotating and sharing the COV19-CT-DB.
The authors affirm no conflicts of interest related to this work.
No financial support was received for this research.
It should be noted that there is a preprint of this paper [23].
The code for this research can be found on GitHub at https://github.com/IDU-CVLab/COV19D_3rd.
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Morani, K., Ayana, E.K., Kollias, D., Unay, D. (2024). Detecting COVID-19 in Computed Tomography Images: A Novel Approach Utilizing Segmentation with UNet Architecture, Lung Extraction, and CNN Classifier. In: Arai, K. (eds) Intelligent Computing. SAI 2024. Lecture Notes in Networks and Systems, vol 1018. Springer, Cham. https://doi.org/10.1007/978-3-031-62269-4_31
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