Abstract
Automated visual evaluation (AVE) of uterine cervix images is a deep learning algorithm that aims to improve cervical pre-cancer screening in low or medium resource regions (LMRR). Image quality control is an important pre-step in the development and use of AVE. In our work, we use data retrospectively collected from different sources/providers for analysis. In addition to good images, the datasets include low-quality images, green-filter images, and post Lugol’s iodine images. The latter two are uncommon in VIA (visual inspection with acetic acid) and should be removed along with low-quality images. In this paper, we apply and compare two state-of-the-art deep learning networks to filter out those two types of cervix images after cervix detection. One of the deep learning networks is DeepSAD, a semi-supervised anomaly detection network, while the other is ResNeSt, an improved variant of the ResNet classification network. Specifically, we study and evaluate the algorithms on a highly unbalanced large dataset consisting of four subsets from different geographic regions acquired with different imaging device types. We also examine the cross-dataset performance of the algorithms. Both networks can achieve high performance (accuracy above 97% and F1 score above 94%) on the test set.
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References
Jeronimo, J., Schiffman, M.: Colposcopy at a crossroads. Am. J. Obstet. Gynecol. 195, 349–353 (2006)
Hu, L., et al.: An observational study of deep learning and automated evaluation of cervical images for cancer screening. J. Natl. Cancer Inst. 111, 923–932 (2019)
Xue, Z., et al.: A demonstration of automated visual evaluation of cervical images taken with a smartphone camera. Int. J. Cancer 147, 2416–2423 (2020)
Pal, A., et al.: Deep metric learning for cervical image classification. IEEE Access 9, 53266–53275 (2021). https://doi.org/10.1109/ACCESS.2021.3069346
Guo, P., et al.: Network visualization and pyramidal feature comparison for ablative treatability classification using digitized cervix images. J. Clin. Med. 10(5), 953 (2021). https://doi.org/10.3390/jcm10050953
Guo, P., et al.: Ensemble deep learning for cervix image selection toward improving reliability in automated cervical precancer screening. Diagnostics (Basel, Switz.) 10(7), 451 (2020). https://doi.org/10.3390/diagnostics10070451
Guo, P., Xue, Z., Long, L.R., Antani, S.: Deep learning for assessing image focus for automated cervical cancer screening. In: Proceedings of the IEEE International Conference on Biomedical and Health Informatics, Chicago, IL, USA, 19–22 May 2019 (2019)
Digiovanni, S.L., Guaragnella, C., Rizzi, M., Falagario, M.: Healthcare system: a digital green filter for smart health early cervical cancer diagnosis. In: IEEE 2nd International Forum on Research and Technologies for Society and Industry Leveraging a better tomorrow (RTSI), Bologna, Italy, pp. 1–6 (2016). https://doi.org/10.1109/RTSI.2016.7740564
Sellors, J.W., Sankaranarayanan, R. (eds.): An introduction to colposcopy: indications for colposcopy, instrumentation, principles and documentation of results. Colposcopy and treatment of cervical intraepithelial neoplasia: a beginners’ manual. https://screening.iarc.fr/colpochap.php?lang=1&chap=4
Yue, Z., et al.: Automatic CIN grades prediction of sequential cervigram image using LSTM with multistate CNN features. IEEE J. Biomed. Health Inform. 24(3), 844–854 (2020). https://doi.org/10.1109/JBHI.2019.2922682
Desai, K.T., et al.: Design and feasibility of a novel program of cervical screening in Nigeria: self-sampled HPV testing paired with visual triage. Infect. Agents Cancer 15, 60 (2020). https://doi.org/10.1186/s13027-020-00324-5
Lin, T., Goyal, P., Girshick, R., He, K., Dollár, P.: Focal loss for dense object detection. In: 2017 IEEE International Conference on Computer Vision (ICCV), Venice, Italy, pp. 2999–3007 (2017). https://doi.org/10.1109/ICCV.2017.324
Chalapathy, R., Chawla, S.: Deep learning for anomaly detection: a survey. https://arxiv.org/abs/1901.03407
Ruff, L., et al.: Deep semi-supervised anomaly detection. In: The International Conference on Learning Representations (ICLR) (2020)
Ruff, L., et al.: Deep one-class classification. In: Proceedings of the 35th International Conference on Machine Learning, PMLR, vol. 80, pp. 4393–4402 (2018)
Zhang, H., et al.: ResNeSt: split-attention networks. https://arxiv.org/abs/2004.08955
Xie, S., Girshick, R., Dollár, P., Tu, Z., He, K.: Aggregated residual transformations for deep neural networks. https://arxiv.org/abs/1611.05431
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This research was supported by the Intramural Research Programs of the National Library of Medicine (NLM) and the National Cancer Institute (NCI), both part of the National Institutes of Health.
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Xue, Z. et al. (2022). Cleaning Highly Unbalanced Multisource Image Dataset for Quality Control in Cervical Precancer Screening. In: Santosh, K., Hegadi, R., Pal, U. (eds) Recent Trends in Image Processing and Pattern Recognition. RTIP2R 2021. Communications in Computer and Information Science, vol 1576. Springer, Cham. https://doi.org/10.1007/978-3-031-07005-1_1
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