Abstract
This paper describes a novel intelligent analysis technique based upon bivariate Markov model that integrates morphological and temporal features with a rule-based interval analysis of ECG signals to localize and accurately classify the premature beats to four major classes: (1) Premature Atrial Complex (PAC), (2) Blocked PAC (B-PAC), (3) Premature Ventricular Complex (PVC), and (4) Premature Junctional Complex (PJC). The paper also describes a beat-pattern classification algorithm to sub classify premature beat-patterns into bigeminy, trigeminy and quadrigeminy. The approach utilizes two phases: (1) a training phase that builds bivariate Markov model from standardized databases of ECG signals, and (2) a dynamic phase that detects embedded P and R waves in T-waves of premature beats using a combination of area subtraction and clinically significant rule-based analysis of R-R intervals. It detects and classifies premature beats using graph matching based upon the forward-backward algorithm and performs a look ahead pattern analysis for the sub-classification of beat-patterns. The algorithms have been presented. The software has been implemented that uses a combination of MATLAB and C++ libraries. Performance results show that processing time is realistic for real-time detection with 98%–99% sensitivity for the premature beat classification and 95%-98% sensitivity for the beat pattern identification.
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References
Zipes, D.P., Camm, A.J., Borggrefe, M., Buxton, A.E., Chaitan, B., Fromer, M., et al.: ACC/AHA/ESC 2006 guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death. J. Am. Coll. Cardiol. 48(5), e247–e346 (2006)
Rautaharju, P.M., Surawicz, B., Gettes, L.S.: AHA/ACCF/HRS recommendations for the standardization and interpretation of the electrocardiogram: part IV. J. Am. Coll. Cardiol. 53(11), 982–991 (2009)
Thong, T., McNames, J., Aboy, M., Goldstein, B.: Prediction of paroxysmal atrial fibrillation by analysis of atrial premature complexes. IEEE Trans. Biomed. Eng. 51(4), 561–569 (2004)
Lerma, C., Glass, L.: Predicting the risk of sudden cardiac death. J. Physiol. 594(9), 2445–2458 (2016)
Chong, B.H., Pong, V., Lam, K.F., Liu, S., Zuo, M.L., Lau, Y.F., et al.: Frequent premature atrial complexes predict new occurrence of atrial fibrillation and adverse cardiovascular events. Europace 13(7), 942–947 (2011)
Tsipouras, M.G., Fotiadis, D.I., Sideris, D.: An arrhythmia classification system based on the RR-interval signal. Artif. Intell. Med. 33(3), 237–250 (2005)
Goldberger, A.L., Amaral, L.A.N., Glass, L., Hausdroff, J.M., Ivanov, P.C.H., Mark, R.G., et al.: Physiobank, physiotoolkit and physionet components of a new research resource for complex physiologic signals. Circulation 101(23), e215–e220
Palaniappan, R., Krishnan, S.: Detection of ectopic heartbeats using ECG and blood pressure. In: International Conference on Signal Processing & Communications (SPCOM 2004), pp. 573–576. Bangalore, India (2004)
Sayadi, O., Mohammad, B., Shamsollahi, M.B., Clifford, G.D.: Robust detection of premature ventricular contractions using a wave-based Bayesian framework. IEEE Trans. Biomed. Eng. 57(2), 353–362 (2010)
Lim, J.S.: Finding features for real-time premature ventricular contraction detection using a fuzzy neural network system. IEEE Trans. Neural Networks 20(3), 522–527 (2009)
Jankowski, S., Dusza, J.J., Wierzbowski, M. Oręziak, A.: SVM detection of premature ectopic excitations based on modified PCA. In: International Symposium of Biological and Medical Data Analysis, Lecture Notes in Computer Science, vol. 3745, pp. 173–183. Aveiro, Portugal, Nov 2005
Smilde, T.D.J., van Veldhuisen, D.J., van den Berg, M.P.: Prognostic value of heart rate variability and ventricular arrhythmias during 13-year follow-up in patients with mild to moderate heart failure. Clin. Res. Cardiol. 98(4), 233–239 (2009)
Garcia, T.B., Miller, G.T.: Arrhythmia Recognition: The Art of Interpretation. Jones and Bartlett (2013)
Kerin, N., Mori, I., Levy, M.N.: Ventricular quadrigeminy as a manifestation of concealed bigeminy. Circulation 52(6), 1023–1029 (1975)
Chiang, L.H., Kotanchek, M.E., Kordon, A.K.: Fault diagnosis based on Fisher discriminant analysis and support vector machines. Comput. Chem. Eng. 28(8), 1389–1401 (2004)
Gawde, P.R., Bansal, A.K., Nielson, J.A.: ECG analysis for automated diagnosis of subclasses of supraventricular arrhythmia. In: Arabnia, H.R., Deligiannidid, L. (eds.) International Conference on Health Informatics and Medical Systems, pp. 10–16. Las Vegas, Nevada, USA, July 2015
Elgendi M., Jonkman, M., De Boer, F.: Premature atrial complexes detection using the Fisher linear discriminant. In: 7th IEEE International Conference on Cognitive Informatics (ICCI 2008), pp. 83–88. Stanford University, CA, USA, Aug 2008
Ching, W., Ng, M.K., Fung, E.S.: Higher-order multivariate Markov chains and their applications. Linear Algebra Appl. 428(2–3), 492–507 (2008)
Tallarida, R.J., Murray, R.B.: Area under a curve: trapezoidal and Simpson’s rules. In: Manual of Pharmacologic Calculations, pp. 77–81. Springer, New York, NY (1987)
Mahmoodabadi, S.Z., Ahmadian, A., Abolhasani, M.D.: ECG feature extraction using Daubechies wavelets. In: Proceedings of the Fifth IASTED International Conference on Visualization, Imaging and Image Processing, pp. 343–348. Benidorm, Spain (2005)
Gawde, P.R., Bansal, A.K., Nielson, J.A.: Integrating Markov model and morphology analysis for finer classification of ventricular arrhythmia in real-time. In: IEEE International Conference on Biomedical & Health Informatics, pp. 409–412. Orlando, FL, USA (2017)
Russell, S., Norwig, P.: Artificial Intelligence—A Modern Approach, 3rd edn. Prentice Hall (2010)
Silva, I., Moody, G.: An open-source toolbox for analysing and processing PhysioNet databases in MATLAB and Octave. J. Open Res. Softw. 2(1), e27 (2014)
Everitt, B., Skrondal, A.: The Cambridge Dictionary of Statistics, vol. 106. Cambridge University Press, Cambridge, UK (2002)
Lin, C., Du, Y., Chen, Y., Chen, T.: Multiple ECG beats recognition in the frequency domain using grey relational analysis. In: Proceedings of the 28th IEEE EMBS Annual International Conference, pp. 2154–2158. New York City, USA. Sept 2006
Ideka, N., Takayanagi, K., Takeuchi, A., Takayanagi, A., Miyahara, H.: Two types of distribution patterns of bigeminy and trigeminy in long-term ECG: a model-based interpretation. In: Computers in Cardiology, vol. 35, pp. 1049–1052. Bologna, Italy, Sept 2008
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Gawde, P.R., Bansal, A.K., Nielson, J.A., Khan, J.I. (2019). Bivariate Markov Model Based Analysis of ECG for Accurate Identification and Classification of Premature Heartbeats and Irregular Beat-Patterns. In: Arai, K., Kapoor, S., Bhatia, R. (eds) Intelligent Systems and Applications. IntelliSys 2018. Advances in Intelligent Systems and Computing, vol 869. Springer, Cham. https://doi.org/10.1007/978-3-030-01057-7_22
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