IRIS Assessments | IRIS | US EPA

IRIS

IRIS Assessments

This page provides a list of final IRIS assessments in alphabetical order by chemical name.   

  Chemical Name CASRN Last Significant Revision* Literature Screening Review Critical Effect Systems RfD Value (Chronic) RfD Value (Subchronic) RfC Value (Chronic) RfC Value (Subchronic) Tumor Site Pesticide Archive
1 Acenaphthene 83-32-9 19901101 Nov-01-1990 No Hepatic
6 x 10 -2 mg/kg-day None
2 Acenaphthylene 208-96-8 19910101 Jan-01-1991 No None None
3 Acephate 30560-19-1 19890501 May-01-1989 Yes Nervous
4 x 10 -3 mg/kg-day Hepatic
pesticide archive
4 Acetaldehyde 75-07-0 19911001 Oct-01-1991 No
Nervous
Respiratory
9 x 10 -3 mg/m3 Respiratory
5 Acetochlor 34256-82-1 19930901 Sep-01-1993 Yes
Hematologic
Hepatic
Nervous
Reproductive
Urinary
2 x 10 -2 mg/kg-day None pesticide
6 Acetone 67-64-1 20030731 Jul-31-2003 No Urinary
9 x 10 -1 mg/kg-day None
7 Acetonitrile 75-05-8 19990303 Mar-03-1999 No None 6 x 10 -2 mg/m3 None
8 Acetophenone 98-86-2 19910201 Feb-01-1991 Yes None 1 x 10 -1 mg/kg-day None
9 Acetyl chloride 75-36-5 19910301 Mar-01-1991 No None None
10 Acifluorfen, sodium 62476-59-9 19870331 Mar-31-1987 Yes
Developmental
Urinary
1.3 x 10 -2 mg/kg-day None pesticide
11 Acrolein 107-02-8 20030603 Jun-03-2003 No Respiratory
5 x 10 -4 mg/kg-day 2 x 10 -5 mg/m3 None
12 Acrylamide 79-06-1 20100322 Mar-22-2010 No Nervous
2 x 10 -3 mg/kg-day 6 x 10 -3 mg/m3
Endocrine
Reproductive
13 Acrylic acid 79-10-7 19940401 Apr-01-1994 Yes
Developmental
Nervous
Respiratory
5 x 10 -1 mg/kg-day 1 x 10 -3 mg/m3 None
14 Acrylonitrile 107-13-1 19911101 Nov-01-1991 Yes Respiratory
2 x 10 -3 mg/m3
Gastrointestinal
Nervous
Respiratory
15 Adiponitrile 111-69-3 19910201 Feb-01-1991 Yes None None
16 Alachlor 15972-60-8 19930901 Sep-01-1993 No Hematologic
1 x 10 -2 mg/kg-day None pesticide
17 Alar 1596-84-5 19880630 Jun-30-1988 Yes None 1.5 x 10 -1 mg/kg-day None pesticide
18 Aldicarb 116-06-3 19931101 Nov-01-1993 Yes Nervous
1 x 10 -3 mg/kg-day None pesticide
19 Aldicarb sulfone 1646-88-4 19931101 Nov-01-1993 Yes Nervous
1 x 10 -3 mg/kg-day None
20 Aldrin 309-00-2 19870930 Sep-30-1987 Yes Hepatic
3 x 10 -5 mg/kg-day Hepatic
pesticide
21 Ally 74223-64-6 19880630 Jun-30-1988 Yes None 2.5 x 10 -1 mg/kg-day None pesticide
22 Allyl alcohol 107-18-6 19870131 Jan-31-1987 Yes
Hepatic
Urinary
5 x 10 -3 mg/kg-day None
23 Allyl chloride 107-05-1 19911201 Dec-01-1991 Yes Nervous
1 x 10 -3 mg/m3 None
24 Aluminum phosphide 20859-73-8 19870131 Jan-31-1987 Yes None 4 x 10 -4 mg/kg-day None pesticide
25 Amdro 67485-29-4 19870930 Sep-30-1987 Yes Hepatic
3 x 10 -4 mg/kg-day None pesticide archive
26 Ametryn 834-12-8 19870930 Sep-30-1987 Yes Hepatic
9 x 10 -3 mg/kg-day None pesticide
27 4-Aminopyridine 504-24-5 19891201 Dec-01-1989 Yes None None pesticide
28 Amitraz 33089-61-1 19880822 Aug-22-1988 Yes Hematologic
2.5 x 10 -3 mg/kg-day None pesticide
29 Ammonia 7664-41-7 20160920 Sep-20-2016 Yes Respiratory
5 x 10 -1 mg/m3 None
30 Ammonium acetate 631-61-8 19910301 Mar-01-1991 No None None
31 Ammonium methacrylate 16325-47-6 19910301 Mar-01-1991 No None None
32 Ammonium sulfamate 7773-06-0 19890101 Jan-01-1989 Yes None 2 x 10 -1 mg/kg-day None
33 Aniline 62-53-3 19901101 Nov-01-1990 Yes Hematologic
1 x 10 -3 mg/m3 Immune
34 ortho-Anisidine 90-04-0 19911001 Oct-01-1991 Yes None None archive
35 Anthracene 120-12-7 19910101 Jan-01-1991 No None 3 x 10 -1 mg/kg-day None
36 Antimony 7440-36-0 19870131 Jan-31-1987 Yes Hematologic
4 x 10 -4 mg/kg-day None
37 Antimony trioxide 1309-64-4 19950901 Sep-01-1995 Yes Respiratory
2 x 10 -4 mg/m3 None
38 Apollo 74115-24-5 19910601 Jun-01-1991 Yes
Endocrine
Hepatic
1.3 x 10 -2 mg/kg-day None pesticide
39 Aramite 140-57-8 19910601 Jun-01-1991 Yes None Hepatic
40 Aroclor 1016 12674-11-2 19930101 Jan-01-1993 No Developmental
7 x 10 -5 mg/kg-day None
41 Aroclor 1248 12672-29-6 19940401 Apr-01-1994 No None None
42 Aroclor 1254 11097-69-1 19941001 Oct-01-1994 No
Dermal
Immune
Ocular
2 x 10 -5 mg/kg-day None
43 Arsenic, Inorganic 7440-38-2 19950601 Jun-01-1995 Yes
Cardiovascular
Dermal
3 x 10 -4 mg/kg-day
Dermal
Respiratory
44 Arsine 7784-42-1 19940301 Mar-01-1994 Yes
Hematologic
Immune
5 x 10 -5 mg/m3 None
45 Asbestos 1332-21-4 19880926 Sep-26-1988 No None Respiratory
46 Assure 76578-14-8 19910601 Jun-01-1991 Yes Hepatic
9 x 10 -3 mg/kg-day None pesticide
47 Asulam 3337-71-1 19880630 Jun-30-1988 Yes
Hepatic
Reproductive
5 x 10 -2 mg/kg-day None pesticide archive
48 Atrazine 1912-24-9 19931001 Oct-01-1993 Yes None 3.5 x 10 -2 mg/kg-day None pesticide
49 Avermectin B1 65195-55-3 19890701 Jul-01-1989 Yes Developmental
4 x 10 -4 mg/kg-day None pesticide
50 Azobenzene 103-33-3 19880907 Sep-07-1988 Yes None None
51 Barium and Compounds 7440-39-3 20050711 Jul-11-2005 Yes Urinary
2 x 10 -1 mg/kg-day None
52 Barium cyanide 542-62-1 19910301 Mar-01-1991 No None None archive
53 Baygon 114-26-1 19870930 Sep-30-1987 Yes Nervous
4 x 10 -3 mg/kg-day None pesticide
54 Bayleton 43121-43-3 19880301 Mar-01-1988 Yes Hematologic
3 x 10 -2 mg/kg-day None pesticide archive
55 Baythroid 68359-37-5 19880301 Mar-01-1988 Yes Urinary
2.5 x 10 -2 mg/kg-day None pesticide
56 Benefin 1861-40-1 19870331 Mar-31-1987 Yes Hematologic
3 x 10 -1 mg/kg-day None pesticide archive
57 Benomyl 17804-35-2 19870131 Jan-31-1987 Yes Developmental
5 x 10 -2 mg/kg-day None pesticide
58 Bentazon (Basagran) 25057-89-0 19980302 Mar-02-1998 Yes Hematologic
3 x 10 -2 mg/kg-day None pesticide
59 Benz[a]anthracene 56-55-3 19901201 Dec-01-1990 No None None
60 Benzaldehyde 100-52-7 19880907 Sep-07-1988 Yes
Gastrointestinal
Urinary
1 x 10 -1 mg/kg-day None
61 Benzene 71-43-2 20030417 Apr-17-2003 No Immune
4 x 10 -3 mg/kg-day 3 x 10 -2 mg/m3 Hematologic
62 Benzidine 92-87-5 19910701 Jul-01-1991 Yes
Hepatic
Nervous
3 x 10 -3 mg/kg-day Urinary
63 Benzo[a]pyrene (BaP) 50-32-8 20170119 Jan-19-2017 No
Developmental
Immune
Reproductive
3 x 10 -4 mg/kg-day 2 x 10 -6 mg/m3
Gastrointestinal
Respiratory
64 Benzo[b]fluoranthene 205-99-2 19901201 Dec-01-1990 No None None
65 Benzo[g,h,i]perylene 191-24-2 19901201 Dec-01-1990 No None None
66 Benzo[k]fluoranthene 207-08-9 19901101 Nov-01-1990 No None None
67 Benzoic acid 65-85-0 19890801 Aug-01-1989 Yes None 4 mg/kg-day None
68 Benzotrichloride 98-07-7 19900701 Jul-01-1990 No None Respiratory
69 Benzyl chloride 100-44-7 19920101 Jan-01-1992 Yes None Endocrine
70 Beryllium and compounds 7440-41-7 19980403 Apr-03-1998 Yes
Gastrointestinal
Immune
Respiratory
2 x 10 -3 mg/kg-day 2 x 10 -5 mg/m3 Respiratory
71 Bidrin 141-66-2 19870930 Sep-30-1987 Yes Reproductive
1 x 10 -4 mg/kg-day None pesticide archive
72 Biphenthrin 82657-04-3 19880822 Aug-22-1988 Yes Nervous
1.5 x 10 -2 mg/kg-day None pesticide
73 Biphenyl 92-52-4 20130827 Aug-27-2013 Yes Urinary
5 x 10 -1 mg/kg-day Hepatic
74 Bis(2-chloro-1-methylethyl) ether 108-60-1 19891001 Oct-01-1989 Yes Hematologic
4 x 10 -2 mg/kg-day None
75 Bis(2-chloroethoxy)methane 111-91-1 19910301 Mar-01-1991 Yes None None
76 Bis(chloroethyl)ether (BCEE) 111-44-4 19911001 Oct-01-1991 Yes None Hepatic
77 Bis(chloromethyl)ether (BCME) 542-88-1 19910701 Jul-01-1991 Yes None Respiratory
78 Bisphenol A 80-05-7 19880926 Sep-26-1988 Yes None 5 x 10 -2 mg/kg-day None
79 Boron and Compounds 7440-42-8 20040805 Aug-05-2004 No Developmental
2 x 10 -1 mg/kg-day None
80 Bromate 15541-45-4 20010606 Jun-06-2001 No Urinary
4 x 10 -3 mg/kg-day
Endocrine
Reproductive
Urinary
81 Brominated dibenzofurans None 19901201 Dec-01-1990 No None None
82 Bromobenzene 108-86-1 20090930 Sep-30-2009 No Hepatic
8 x 10 -3 mg/kg-day 2 x 10 -2 mg/kg-day 6 x 10 -2 mg/m3 2 x 10 -1 mg/m3 None
83 Bromochloromethane 74-97-5 19910301 Mar-01-1991 No None None
84 Bromodichloromethane 75-27-4 19930201 Feb-01-1993 Yes Urinary
2 x 10 -2 mg/kg-day Urinary
85 p-Bromodiphenyl ether 101-55-3 19900801 Aug-01-1990 No None None
86 Bromoform 75-25-2 19931201 Dec-01-1993 Yes Hepatic
2 x 10 -2 mg/kg-day Gastrointestinal
87 Bromomethane 74-83-9 19920401 Apr-01-1992 Yes
Gastrointestinal
Nervous
Respiratory
1.4 x 10 -3 mg/kg-day 5 x 10 -3 mg/m3 None
88 Bromotrichloromethane 75-62-7 19910301 Mar-01-1991 Yes None None
89 Bromoxynil 1689-84-5 19880630 Jun-30-1988 No None 2 x 10 -2 mg/kg-day None pesticide archive
90 Bromoxynil octanoate 1689-99-2 19880907 Sep-07-1988 Yes None 2 x 10 -2 mg/kg-day None pesticide archive
91 1,3-Butadiene 106-99-0 20021105 Nov-05-2002 No Reproductive
2 x 10 -3 mg/m3 Hematologic
92 n-Butanol 71-36-3 19910301 Mar-01-1991 Yes Nervous
1 x 10 -1 mg/kg-day None
93 tert-Butyl Alcohol (tBA) 75-65-0 20210813 Aug-13-2021 No Urinary

Endocrine
Urinary
94 Butyl benzyl phthalate (BBP) 85-68-7 19890901 Sep-01-1989 Yes Hepatic
2 x 10 -1 mg/kg-day None
95 Butylate 2008-41-5 19941001 Oct-01-1994 Yes Hepatic
5 x 10 -2 mg/kg-day None pesticide
96 t-Butylchloride 507-20-0 19900401 Apr-01-1990 No None None
97 Butylphthalyl butylglycolate (BPBG) 85-70-1 19870301 Mar-01-1987 No None 1 mg/kg-day None
98 Cacodylic acid 75-60-5 19921101 Nov-01-1992 Yes None None pesticide
99 Cadmium 7440-43-9 19891001 Oct-01-1989 No Urinary
5 x 10 -4 mg/kg-day Respiratory
100 Calcium cyanide 592-01-8 20100928 Sep-28-2010 Yes Reproductive
1 x 10 -3 mg/kg-day None
101 Caprolactam 105-60-2 19940901 Sep-01-1994 Yes Developmental
5 x 10 -1 mg/kg-day None
102 Captafol 2425-06-1 19870930 Sep-30-1987 Yes Urinary
2 x 10 -3 mg/kg-day None pesticide
103 Captan 133-06-2 19890301 Mar-01-1989 No None 1.3 x 10 -1 mg/kg-day None pesticide
104 Carbaryl 63-25-2 19911101 Nov-01-1991 Yes
Hepatic
Urinary
1 x 10 -1 mg/kg-day None pesticide
105 Carbofuran 1563-66-2 19870930 Sep-30-1987 Yes
Nervous
Reproductive
5 x 10 -3 mg/kg-day None pesticide
106 Carbon disulfide 75-15-0 19950801 Aug-01-1995 Yes
Developmental
Nervous
1 x 10 -1 mg/kg-day 7 x 10 -1 mg/m3 None
107 Carbon tetrachloride 56-23-5 20100331 Mar-31-2010 No Hepatic
4 x 10 -3 mg/kg-day 1 x 10 -1 mg/m3
Endocrine
Hepatic
108 Carbonyl sulfide 463-58-1 19911101 Nov-01-1991 Yes None None archive
109 Carbosulfan 55285-14-8 19870131 Jan-31-1987 Yes None 1 x 10 -2 mg/kg-day None
110 Carboxin 5234-68-4 19870131 Jan-31-1987 Yes None 1 x 10 -1 mg/kg-day None pesticide
111 Cerium Oxide and Cerium Compounds 1306-38-3 20090929 Sep-29-2009 No Respiratory
9 x 10 -4 mg/m3 None
112 Chloral hydrate 302-17-0 20000915 Sep-15-2000 Yes
Gastrointestinal
Nervous
1 x 10 -1 mg/kg-day None
113 Chloramben 133-90-4 19870131 Jan-31-1987 Yes Hepatic
1.5 x 10 -2 mg/kg-day None pesticide
114 Chlordane (Technical) 12789-03-6 19980207 Feb-07-1998 Yes Hepatic
5 x 10 -4 mg/kg-day 7 x 10 -4 mg/m3 Hepatic
pesticide
115 Chlordecone (Kepone) 143-50-0 20090922 Sep-22-2009 No Urinary
3 x 10 -4 mg/kg-day Hepatic
pesticide
116 Chlorimuron-ethyl 90982-32-4 19891101 Nov-01-1989 Yes Hematologic
2 x 10 -2 mg/kg-day None pesticide archive
117 Chlorine 7782-50-5 19940601 Jun-01-1994 Yes None 1 x 10 -1 mg/kg-day None
118 Chlorine cyanide 506-77-4 19870131 Jan-31-1987 No
Endocrine
Nervous
5 x 10 -2 mg/kg-day None
119 Chlorine dioxide 10049-04-4 20001011 Oct-11-2000 Yes
Cardiovascular
Developmental
Nervous
Respiratory
3 x 10 -2 mg/kg-day 2 x 10 -4 mg/m3 None
120 Chlorite (sodium salt) 7758-19-2 20001011 Oct-11-2000 No
Developmental
Nervous
3 x 10 -2 mg/kg-day None
121 1-Chloro-1,1-difluoroethane 75-68-3 19950701 Jul-01-1995 No None 5 x 10 1 mg/m3 None
122 2-Chloroacetophenone 532-27-4 19911001 Oct-01-1991 Yes Respiratory
3 x 10 -5 mg/m3 None
123 p-Chloroaniline 106-47-8 19880822 Aug-22-1988 Yes Immune
4 x 10 -3 mg/kg-day None
124 Chlorobenzene 108-90-7 19901101 Nov-01-1990 Yes Hepatic
2 x 10 -2 mg/kg-day None
125 Chlorobenzilate 510-15-6 19891201 Dec-01-1989 Yes Nervous
2 x 10 -2 mg/kg-day None
126 1-Chlorobutane 109-69-3 19900401 Apr-01-1990 No None None
127 2-Chlorobutane 78-86-4 19900401 Apr-01-1990 No None None
128 Chlorocyclopentadiene 41851-50-7 19900301 Mar-01-1990 No None None
129 Chlorodifluoromethane 75-45-6 19931101 Nov-01-1993 Yes
Endocrine
Urinary
5 x 10 1 mg/m3 None
130 Chloroform 67-66-3 20011019 Oct-19-2001 No Hepatic
1 x 10 -2 mg/kg-day Hepatic
131 Chloromethyl methyl ether (CMME) 107-30-2 19870930 Sep-30-1987 No None None
132 beta-Chloronaphthalene 91-58-7 19901101 Nov-01-1990 No
Hepatic
Respiratory
8 x 10 -2 mg/kg-day None
133 2-Chlorophenol 95-57-8 19880822 Aug-22-1988 Yes Reproductive
5 x 10 -3 mg/kg-day None
134 p-Chlorophenyl methyl sulfide 123-09-1 19930601 Jun-01-1993 No None None
135 p-Chlorophenyl methyl sulfone 98-57-7 19930601 Jun-01-1993 Yes None None
136 p-Chlorophenyl methyl sulfoxide 934-73-6 19930601 Jun-01-1993 Yes None None
137 Chloroprene 126-99-8 20100930 Sep-30-2010 No
Immune
Nervous
Respiratory
2 x 10 -2 mg/m3
Dermal
Gastrointestinal
Hepatic
Ocular
Reproductive
Respiratory
138 Chlorothalonil 1897-45-6 19880301 Mar-01-1988 No Urinary
1.5 x 10 -2 mg/kg-day None pesticide
139 o-Chlorotoluene 95-49-8 19900201 Feb-01-1990 Yes None 2 x 10 -2 mg/kg-day None
140 Chlorpropham 101-21-3 19980630 Jun-30-1998 Yes
Hematologic
Hepatic
Immune
Urinary
2 x 10 -1 mg/kg-day None pesticide archive
141 Chlorpyrifos 2921-88-2 20110324 Mar-24-2011 No None None pesticide archive
142 Chlorsulfuron 64902-72-3 19870131 Jan-31-1987 Yes None 5 x 10 -2 mg/kg-day None pesticide archive
143 Chromium(III), insoluble salts 16065-83-1 19980903 Sep-03-1998 Yes None 1.5 mg/kg-day None
144 Chromium(VI) 18540-29-9 20240801 Aug-01-2024 Yes
Gastrointestinal
Respiratory
9 x 10 -4 mg/kg-day 3 x 10 -5 mg/m3
Gastrointestinal
Respiratory
145 Chrysene 218-01-9 19901201 Dec-01-1990 No None None
146 Cobalt and Cobalt Compounds 1307-96-6 No None None
147 Coke oven emissions None 19890501 May-01-1989 Yes None Respiratory
148 Copper 7440-50-8 19880907 Sep-07-1988 No None None
149 Copper cyanide 544-92-3 19880907 Sep-07-1988 No
Hepatic
Urinary
5 x 10 -3 mg/kg-day None
150 Creosote 8001-58-9 19880907 Sep-07-1988 Yes None None
151 Crotonaldehyde 123-73-9 19910601 Jun-01-1991 No None None
152 Cumene 98-82-8 19970801 Aug-01-1997 Yes
Endocrine
Urinary
1 x 10 -1 mg/kg-day 4 x 10 -1 mg/m3 None
153 Cyanazine 21725-46-2 19920701 Jul-01-1992 Yes None None pesticide archive
154 Cyanide, free 57-12-5 20100928 Sep-28-2010 Yes Reproductive
6.3 x 10 -4 mg/kg-day None
155 Cyanogen 460-19-5 20100928 Sep-28-2010 Yes None 1 x 10 -3 mg/kg-day None
156 Cyanogen bromide 506-68-3 19880926 Sep-26-1988 No
Endocrine
Nervous
9 x 10 -2 mg/kg-day None
157 Cyclohexane 110-82-7 20030911 Sep-11-2003 No Developmental
None
158 Cyclohexanone 108-94-1 19870930 Sep-30-1987 Yes None 5 mg/kg-day None
159 Cyclohexylamine 108-91-8 19880907 Sep-07-1988 Yes Reproductive
2 x 10 -1 mg/kg-day None
160 Cyhalothrin/Karate 68085-85-8 19880630 Jun-30-1988 Yes Developmental
5 x 10 -3 mg/kg-day None pesticide archive
161 Cypermethrin 52315-07-8 19890301 Mar-01-1989 No Gastrointestinal
1 x 10 -2 mg/kg-day None pesticide archive
162 Cyromazine 66215-27-8 19870930 Sep-30-1987 No Hematologic
7.5 x 10 -3 mg/kg-day None pesticide archive
163 Dacthal 1861-32-1 19940801 Aug-01-1994 Yes
Endocrine
Hepatic
Ocular
Respiratory
Urinary
1 x 10 -2 mg/kg-day None pesticide
164 Dalapon, sodium salt 75-99-0 19880822 Aug-22-1988 Yes Urinary
3 x 10 -2 mg/kg-day None pesticide
165 Danitol 39515-41-8 19941001 Oct-01-1994 Yes Nervous
2.5 x 10 -2 mg/kg-day None pesticide
166 2,2',3,3',4,4',5,5',6,6'-Decabromodiphenyl ether (BDE-209) 1163-19-5 20080630 Jun-30-2008 Yes Nervous
7 x 10 -3 mg/kg-day Hepatic
167 Demeton 8065-48-3 19870131 Jan-31-1987 Yes Nervous
4 x 10 -5 mg/kg-day None pesticide
168 2,4-Diaminotoluene 95-80-7 19910301 Mar-01-1991 Yes None None
169 Diazomethane 334-88-3 19911101 Nov-01-1991 Yes None None archive
170 Dibenz[a,h]anthracene 53-70-3 19901201 Dec-01-1990 No None None
171 Dibenzofuran 132-64-9 19901001 Oct-01-1990 Yes None None
172 1,2-Dibromo-3-chloropropane (DBCP) 96-12-8 19911001 Oct-01-1991 Yes Reproductive
2 x 10 -4 mg/m3 None
173 1,4-Dibromobenzene 106-37-6 19870331 Mar-31-1987 No Hepatic
1 x 10 -2 mg/kg-day None
174 Dibromochloromethane 124-48-1 19920101 Jan-01-1992 Yes Hepatic
2 x 10 -2 mg/kg-day Hepatic
175 Dibromodichloromethane 594-18-3 19910301 Mar-01-1991 No None None
176 p,p'-Dibromodiphenyl ether 2050-47-7 19900801 Aug-01-1990 No None None
177 1,2-Dibromoethane 106-93-4 20040729 Jul-29-2004 No
Endocrine
Hepatic
Reproductive
Respiratory
9 x 10 -3 mg/kg-day 9 x 10 -3 mg/m3
Endocrine
Gastrointestinal
Reproductive
Respiratory
178 Dibutyl phthalate (DBP) 84-74-2 19901001 Oct-01-1990 Yes None 1 x 10 -1 mg/kg-day None
179 Dicamba 1918-00-9 19880822 Aug-22-1988 Yes Developmental
3 x 10 -2 mg/kg-day None pesticide
180 Dichloroacetic acid 79-43-6 20030911 Sep-11-2003 No
Hepatic
Nervous
Reproductive
Hepatic
181 1,2-Dichlorobenzene 95-50-1 19901101 Nov-01-1990 No None 9 x 10 -2 mg/kg-day None
182 1,3-Dichlorobenzene 541-73-1 19900901 Sep-01-1990 No None None
183 1,4-Dichlorobenzene 106-46-7 19940101 Jan-01-1994 No Hepatic
8 x 10 -1 mg/m3 None
184 3,3'-Dichlorobenzidine 91-94-1 19911101 Nov-01-1991 No None Reproductive
185 Dichlorodifluoromethane 75-71-8 19870131 Jan-31-1987 No None 2 x 10 -1 mg/kg-day None
186 p,p'-Dichlorodiphenyl dichloroethane (DDD) 72-54-8 19880822 Aug-22-1988 Yes None Hepatic
pesticide
187 p,p'-Dichlorodiphenyldichloroethylene (DDE) 72-55-9 19880822 Aug-22-1988 Yes None Hepatic
188 p,p'-Dichlorodiphenyltrichloroethane (DDT) 50-29-3 19880822 Aug-22-1988 Yes Hepatic
5 x 10 -4 mg/kg-day Hepatic
pesticide
189 1,1-Dichloroethane 75-34-3 19901001 Oct-01-1990 Yes None None
190 1,2-Dichloroethane 107-06-2 19870331 Mar-31-1987 No None None
191 cis-1,2-Dichloroethylene 156-59-2 20100930 Sep-30-2010 Yes Urinary
2 x 10 -3 mg/kg-day None
192 trans-1,2-Dichloroethylene 156-60-5 20100930 Sep-30-2010 Yes Immune
2 x 10 -2 mg/kg-day None
193 1,1-Dichloroethylene (1,1-DCE) 75-35-4 20020813 Aug-13-2002 No Hepatic
5 x 10 -2 mg/kg-day 2 x 10 -1 mg/m3 None
194 Dichloromethane 75-09-2 20111118 Nov-18-2011 Yes Hepatic
6 x 10 -3 mg/kg-day 6 x 10 -1 mg/m3
Hepatic
Respiratory
195 2,4-Dichlorophenol 120-83-2 19870131 Jan-31-1987 Yes Immune
3 x 10 -3 mg/kg-day None
196 4-(2,4-Dichlorophenoxy)butyric acid (2,4-DB) 94-82-6 19870131 Jan-31-1987 Yes None 8 x 10 -3 mg/kg-day None pesticide archive
197 2,4-Dichlorophenoxyacetic acid (2,4-D) 94-75-7 19870331 Mar-31-1987 Yes
Hematologic
Hepatic
Urinary
1 x 10 -2 mg/kg-day None pesticide
198 1,2-Dichloropropane 78-87-5 19911201 Dec-01-1991 Yes Respiratory
None
199 2,3-Dichloropropanol 616-23-9 19901101 Nov-01-1990 No
Cardiovascular
Hepatic
Urinary
3 x 10 -3 mg/kg-day None
200 1,3-Dichloropropene 542-75-6 20000525 May-25-2000 Yes
Gastrointestinal
Respiratory
3 x 10 -2 mg/kg-day 2 x 10 -2 mg/m3
Hepatic
Respiratory
Urinary
201 Dichlorvos 62-73-7 19940601 Jun-01-1994 Yes Nervous
5 x 10 -4 mg/kg-day 5 x 10 -4 mg/m3
Endocrine
Gastrointestinal
Hematologic
pesticide
202 Dicofol 115-32-2 19920401 Apr-01-1992 Yes None None pesticide archive
203 Dieldrin 60-57-1 19880907 Sep-07-1988 Yes Hepatic
5 x 10 -5 mg/kg-day Hepatic
204 Diesel engine exhaust None 20030228 Feb-28-2003 No Respiratory
5 x 10 -3 mg/m3 None
205 Diethyl phthalate (DEP) 84-66-2 19880907 Sep-07-1988 Yes None 8 x 10 -1 mg/kg-day None
206 Diethyl sulfate 64-67-5 19911101 Nov-01-1991 Yes None None archive
207 Diethyl-p-nitrophenylphosphate 311-45-5 19921001 Oct-01-1992 No None None
208 Diethylene glycol dinitrate (DEGDN) 693-21-0 19930201 Feb-01-1993 No None None
209 Di(2-ethylhexyl)adipate 103-23-1 19920701 Jul-01-1992 No
Developmental
Hepatic
Musculoskeletal
Urinary
6 x 10 -1 mg/kg-day Hepatic
210 Di (2-ethylhexyl)phthalate (DEHP) 117-81-7 19880907 Sep-07-1988 No Hepatic
2 x 10 -2 mg/kg-day Hepatic
211 Difenzoquat 43222-48-6 19880822 Aug-22-1988 Yes None 8 x 10 -2 mg/kg-day None pesticide archive
212 Diflubenzuron 35367-38-5 19870930 Sep-30-1987 No Hematologic
2 x 10 -2 mg/kg-day None pesticide
213 1,1-Difluoroethane 75-37-6 19940901 Sep-01-1994 No None 4 x 10 1 mg/m3 None
214 Diisobutyl phthalate (DIBP) 84-69-5 No None None
215 Diisononyl phthalate (DINP) 28553-12-0 No None None
216 Diisopropyl methylphosphonate (DIMP) 1445-75-6 19890401 Apr-01-1989 Yes None 8 x 10 -2 mg/kg-day None
217 Dimethipin 55290-64-7 19900501 May-01-1990 Yes Hepatic
2 x 10 -2 mg/kg-day None pesticide archive
218 Dimethoate 60-51-5 19880822 Aug-22-1988 Yes Nervous
2 x 10 -4 mg/kg-day None pesticide archive
219 Dimethyl phthalate 131-11-3 19900901 Sep-01-1990 Yes None None
220 Dimethyl sulfate 77-78-1 19920101 Jan-01-1992 Yes None None
221 Dimethyl terephthalate (DMT) 120-61-6 19870131 Jan-31-1987 Yes Urinary
1 x 10 -1 mg/kg-day None
222 Dimethylamine 124-40-3 19910101 Jan-01-1991 Yes None None archive
223 N-N-Dimethylaniline 121-69-7 19870930 Sep-30-1987 Yes
Hematologic
Immune
2 x 10 -3 mg/kg-day None
224 3,3-Dimethylbenzidine 119-93-7 19910701 Jul-01-1991 Yes None None archive
225 N,N-Dimethylformamide 68-12-2 19901001 Oct-01-1990 Yes Hepatic
3 x 10 -2 mg/m3 None
226 2,4-Dimethylphenol 105-67-9 19901101 Nov-01-1990 Yes
Hematologic
Nervous
2 x 10 -2 mg/kg-day None
227 2,6-Dimethylphenol 576-26-1 19880907 Sep-07-1988 No
Hepatic
Immune
Urinary
6 x 10 -4 mg/kg-day None
228 3,4-Dimethylphenol 95-65-8 19880907 Sep-07-1988 No
Cardiovascular
Hepatic
Immune
Urinary
1 x 10 -3 mg/kg-day None
229 4,6-Dinitro-o-cyclohexyl phenol 131-89-5 19880822 Aug-22-1988 Yes Ocular
2 x 10 -3 mg/kg-day None
230 m-Dinitrobenzene 99-65-0 19910301 Mar-01-1991 No Immune
1 x 10 -4 mg/kg-day None
231 o-Dinitrobenzene 528-29-0 19920901 Sep-01-1992 No None None
232 2,4-Dinitrophenol 51-28-5 19911001 Oct-01-1991 No Ocular
2 x 10 -3 mg/kg-day None
233 2,4-Dinitrotoluene 121-14-2 19920601 Jun-01-1992 Yes
Hematologic
Hepatic
Nervous
2 x 10 -3 mg/kg-day None
234 2,4-/2,6-Dinitrotoluene mixture Various 19900901 Sep-01-1990 Yes None
Hepatic
Reproductive
235 Dinoseb 88-85-7 19890801 Aug-01-1989 Yes Developmental
1 x 10 -3 mg/kg-day None pesticide
236 1,4-Dioxane 123-91-1 20130920 Sep-20-2013 Yes
Hepatic
Nervous
Respiratory
Urinary

Gastrointestinal
Hepatic
Reproductive
Respiratory
Urinary
237 Diphenamid 957-51-7 19870930 Sep-30-1987 Yes Hepatic
3 x 10 -2 mg/kg-day None pesticide
238 Diphenylamine 122-39-4 19870131 Jan-31-1987 Yes
Hepatic
Urinary
2.5 x 10 -2 mg/kg-day None pesticide archive
239 1,2-Diphenylhydrazine 122-66-7 19911101 Nov-01-1991 No None Hepatic
240 Diquat 2764-72-9 19870331 Mar-31-1987 Yes Ocular
2.2 x 10 -3 mg/kg-day None pesticide
241 Disulfoton 298-04-4 19870331 Mar-31-1987 Yes Nervous
4 x 10 -5 mg/kg-day None pesticide
242 1,4-Dithiane 505-29-3 19930301 Mar-01-1993 No
Nervous
Respiratory
1 x 10 -2 mg/kg-day None
243 Diuron 330-54-1 19880822 Aug-22-1988 Yes Hematologic
2 x 10 -3 mg/kg-day None pesticide
244 Dodine 2439-10-3 19870930 Sep-30-1987 Yes Endocrine
4 x 10 -3 mg/kg-day None pesticide archive
245 Endosulfan 115-29-7 19941001 Oct-01-1994 Yes
Cardiovascular
Urinary
6 x 10 -3 mg/kg-day None pesticide
246 Endothall 145-73-3 19870331 Mar-31-1987 Yes Gastrointestinal
2 x 10 -2 mg/kg-day None pesticide
247 Endrin 72-20-8 19891001 Oct-01-1989 Yes
Hepatic
Nervous
3 x 10 -4 mg/kg-day None pesticide
248 Epichlorohydrin 106-89-8 19920401 Apr-01-1992 Yes Respiratory
1 x 10 -3 mg/m3
Gastrointestinal
Respiratory
249 1,2-Epoxybutane (EBU) 106-88-7 19920501 May-01-1992 Yes Respiratory
2 x 10 -2 mg/m3 None
250 Ethephon 16672-87-0 19880822 Aug-22-1988 Yes Nervous
5 x 10 -3 mg/kg-day None pesticide
251 Ethion 563-12-2 19890901 Sep-01-1989 No Nervous
5 x 10 -4 mg/kg-day None pesticide
252 2-Ethoxyethanol 110-80-5 19910501 May-01-1991 Yes
Hematologic
Reproductive
2 x 10 -1 mg/m3 None
253 Ethyl acetate 141-78-6 19870301 Mar-01-1987 Yes None 9 x 10 -1 mg/kg-day None
254 Ethyl carbamate 51-79-6 19920401 Apr-01-1992 Yes None None archive
255 Ethyl chloride 75-00-3 19910401 Apr-01-1991 No
Developmental
Musculoskeletal
1 x 10 1 mg/m3 None
256 S-Ethyl dipropylthiocarbamate (EPTC) 759-94-4 19870930 Sep-30-1987 Yes Cardiovascular
2.5 x 10 -2 mg/kg-day None pesticide archive
257 Ethyl ether 60-29-7 19900901 Sep-01-1990 Yes None 2 x 10 -1 mg/kg-day None
258 Ethyl p-nitrophenyl phenylphosphorothioate (EPN) 2104-64-5 19870930 Sep-30-1987 Yes Nervous
1 x 10 -5 mg/kg-day None
259 Ethyl Tertiary Butyl Ether (ETBE) 637-92-3 20210813 Aug-13-2021 No Urinary
Hepatic
260 Ethylbenzene 100-41-4 19910301 Mar-01-1991 No
Developmental
Hepatic
Urinary
1 x 10 -1 mg/kg-day 1 mg/m3 None
261 Ethylene diamine 107-15-3 19921101 Nov-01-1992 Yes None None
262 Ethylene glycol 107-21-1 19870930 Sep-30-1987 Yes Urinary
2 mg/kg-day None
263 Ethylene glycol monobutyl ether (EGBE) (2-Butoxyethanol) 111-76-2 20100331 Mar-31-2010 No Hematologic
1 x 10 -1 mg/kg-day 1.6 mg/m3 None
264 Ethylene oxide 75-21-8 20161216 Dec-16-2016 No None
Immune
Reproductive
265 Ethylene thiourea (ETU) 96-45-7 19910501 May-01-1991 Yes Endocrine
8 x 10 -5 mg/kg-day None
266 Ethyleneimine 151-56-4 19920401 Apr-01-1992 Yes None None archive
267 Ethylphthalyl ethylglycolate (EPEG) 84-72-0 19870131 Jan-31-1987 No Urinary
3 mg/kg-day None
268 Express 101200-48-0 19890101 Jan-01-1989 Yes Urinary
8 x 10 -3 mg/kg-day None pesticide
269 Fenamiphos 22224-92-6 19870930 Sep-30-1987 Yes Nervous
2.5 x 10 -4 mg/kg-day None pesticide
270 Fluometuron 2164-17-2 19870930 Sep-30-1987 Yes None 1.3 x 10 -2 mg/kg-day None pesticide
271 Fluoranthene 206-44-0 19901201 Dec-01-1990 No
Hepatic
Urinary
4 x 10 -2 mg/kg-day None
272 Fluorene 86-73-7 19901201 Dec-01-1990 No Hematologic
4 x 10 -2 mg/kg-day None
273 Fluorine (soluble fluoride) 7782-41-4 19870131 Jan-31-1987 Yes Gastrointestinal
6 x 10 -2 mg/kg-day None
274 Fluridone 59756-60-4 19880822 Aug-22-1988 Yes
Ocular
Reproductive
Urinary
8 x 10 -2 mg/kg-day None pesticide
275 Flurprimidol 56425-91-3 19890701 Jul-01-1989 Yes Hepatic
2 x 10 -2 mg/kg-day None pesticide archive
276 Flutolanil 66332-96-5 19890501 May-01-1989 Yes
Hepatic
Reproductive
6 x 10 -2 mg/kg-day None pesticide archive
277 Fluvalinate 69409-94-5 19880630 Jun-30-1988 Yes Dermal
1 x 10 -2 mg/kg-day None pesticide
278 Folpet 133-07-3 19880822 Aug-22-1988 Yes Hepatic
1 x 10 -1 mg/kg-day Gastrointestinal
pesticide archive
279 Fomesafen 72178-02-0 19880822 Aug-22-1988 Yes None Hepatic
pesticide archive
280 Fonofos 944-22-9 19870331 Mar-31-1987 Yes
Hepatic
Nervous
2 x 10 -3 mg/kg-day None pesticide
281 Formaldehyde 50-00-0 20240819 Aug-19-2024 No
Gastrointestinal
Respiratory
Urinary
2 x 10 -1 mg/kg-day 7 x 10 -3 mg/m3
Hematologic
Respiratory
282 Formic acid 64-18-6 19901201 Dec-01-1990 Yes None None archive
283 Fosetyl-al 39148-24-8 19880822 Aug-22-1988 Yes Reproductive
3 mg/kg-day None pesticide archive
284 Furan 110-00-9 19870131 Jan-31-1987 Yes Hepatic
1 x 10 -3 mg/kg-day None
285 Furfural 98-01-1 19880907 Sep-07-1988 Yes Hepatic
3 x 10 -3 mg/kg-day None pesticide
286 Furmecyclox 60568-05-0 19880907 Sep-07-1988 Yes None Hepatic
287 Glufosinate-ammonium 77182-82-2 19870930 Sep-30-1987 Yes Urinary
4 x 10 -4 mg/kg-day None pesticide archive
288 Glycidaldehyde 765-34-4 19910801 Aug-01-1991 No
Endocrine
Hematologic
Urinary
4 x 10 -4 mg/kg-day None
289 Glyphosate 1071-83-6 19891001 Oct-01-1989 No
Developmental
Urinary
1 x 10 -1 mg/kg-day None pesticide
290 Haloxyfop-methyl 69806-40-2 19900501 May-01-1990 Yes
Reproductive
Urinary
5 x 10 -5 mg/kg-day None pesticide
291 Harmony 79277-27-3 19880926 Sep-26-1988 Yes None 1.3 x 10 -2 mg/kg-day None pesticide archive
292 Heptachlor 76-44-8 19870930 Sep-30-1987 Yes Hepatic
5 x 10 -4 mg/kg-day Hepatic
pesticide
293 Heptachlor epoxide 1024-57-3 19870930 Sep-30-1987 Yes Hepatic
1.3 x 10 -5 mg/kg-day Hepatic
pesticide
294 n-Heptane 142-82-5 19930101 Jan-01-1993 Yes None None
295 Hexabromobenzene 87-82-1 19870331 Mar-31-1987 No Hepatic
2 x 10 -3 mg/kg-day None
296 Hexabromocyclododecane (HBCD) 3194-55-6 No None None
297 2,2',4,4',5,5'-Hexabromodiphenyl ether (BDE-153) 68631-49-2 20080630 Jun-30-2008 No Nervous
2 x 10 -4 mg/kg-day None
298 Hexabromodiphenyl ether 36483-60-0 19900801 Aug-01-1990 Yes None None
299 Hexachlorobenzene 118-74-1 19910301 Mar-01-1991 Yes Hepatic
8 x 10 -4 mg/kg-day Hepatic
300 Hexachlorobutadiene 87-68-3 19930501 May-01-1993 No None Urinary
301 alpha-Hexachlorocyclohexane (alpha-HCH) 319-84-6 19870331 Mar-31-1987 Yes None Hepatic
302 beta-Hexachlorocyclohexane (beta-HCH) 319-85-7 19870930 Sep-30-1987 Yes None Hepatic
303 delta-Hexachlorocyclohexane (delta-HCH) 319-86-8 19870331 Mar-31-1987 Yes None None
304 epsilon-Hexachlorocyclohexane (epsilon-HC) 6108-10-7 19870331 Mar-31-1987 Yes None None
305 gamma-Hexachlorocyclohexane (gamma-HCH) 58-89-9 19870131 Jan-31-1987 No
Hepatic
Urinary
3 x 10 -4 mg/kg-day None pesticide
306 technical Hexachlorocyclohexane (t-HCH) 608-73-1 19870331 Mar-31-1987 Yes None Hepatic
pesticide
307 Hexachlorocyclopentadiene (HCCPD) 77-47-4 20010705 Jul-05-2001 Yes
Gastrointestinal
Respiratory
6 x 10 -3 mg/kg-day 2 x 10 -4 mg/m3 None
308 Hexachlorodibenzo-p-dioxin (HxCDD), mixture of 1,2,3,6,7,8-HxCDD and 1,2,3,7,8,9-HxCDD 57653-85-7 19870331 Mar-31-1987 Yes None Hepatic
309 Hexachloroethane 67-72-1 20110923 Sep-23-2011 Yes
Nervous
Urinary
7 x 10 -4 mg/kg-day 3 x 10 -2 mg/m3 Urinary
310 Hexachlorophene 70-30-4 19880822 Aug-22-1988 Yes
Gastrointestinal
Nervous
3 x 10 -4 mg/kg-day None
311 Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) 121-82-4 20180830 Aug-30-2018 No
Nervous
Reproductive
Urinary
4 x 10 -3 mg/kg-day
Hepatic
Respiratory
312 1,6-Hexamethylene diisocyanate 822-06-0 19940901 Sep-01-1994 Yes
Nervous
Respiratory
1 x 10 -5 mg/m3 None
313 n-Hexane 110-54-3 20051223 Dec-23-2005 Yes Nervous
7 x 10 -1 mg/m3 None
314 2-Hexanone 591-78-6 20090925 Sep-25-2009 No Nervous
5 x 10 -3 mg/kg-day 3 x 10 -2 mg/m3 None
315 Hexazinone 51235-04-2 19870930 Sep-30-1987 Yes None 3.3 x 10 -2 mg/kg-day None pesticide
316 Hydrazine/Hydrazine sulfate 302-01-2 19880907 Sep-07-1988 Yes None
Hepatic
Respiratory
317 Hydrogen chloride 7647-01-0 19950701 Jul-01-1995 Yes Respiratory
2 x 10 -2 mg/m3 None
318 Hydrogen Cyanide and Cyanide Salts Various 20100928 Sep-28-2010 No
Endocrine
Reproductive
6 x 10 -4 mg/kg-day 8 x 10 -4 mg/m3 None
319 Hydrogen sulfide 7783-06-4 20030728 Jul-28-2003 No
Nervous
Respiratory
2 x 10 -3 mg/m3 None
320 Hydroquinone 123-31-9 19901001 Oct-01-1990 Yes None None archive
321 Imazalil 35554-44-0 19870331 Mar-31-1987 Yes None 1.3 x 10 -2 mg/kg-day None pesticide archive
322 Imazaquin 81335-37-7 19870131 Jan-31-1987 Yes
Hematologic
Hepatic
Immune
2.5 x 10 -1 mg/kg-day None pesticide
323 Indeno[1,2,3-cd]pyrene 193-39-5 19901201 Dec-01-1990 No None None
324 Iprodione 36734-19-7 19880630 Jun-30-1988 Yes
Hematologic
Reproductive
4 x 10 -2 mg/kg-day None pesticide
325 Isobutyl alcohol 78-83-1 19870331 Mar-31-1987 Yes Nervous
3 x 10 -1 mg/kg-day None
326 Isophorone 78-59-1 19921001 Oct-01-1992 Yes Urinary
2 x 10 -1 mg/kg-day Reproductive
327 Isopropalin 33820-53-0 19870131 Jan-31-1987 Yes Hematologic
1.5 x 10 -2 mg/kg-day None
328 Isopropyl methyl phosphonic acid (IMPA) 1832-54-8 19920601 Jun-01-1992 No None 1 x 10 -1 mg/kg-day None
329 Isoxaben 82558-50-7 19910901 Sep-01-1991 Yes
Cardiovascular
Hepatic
Urinary
5 x 10 -2 mg/kg-day None pesticide
330 Lactofen 77501-63-4 19880630 Jun-30-1988 Yes Hepatic
2 x 10 -3 mg/kg-day None pesticide archive
331 Lead and compounds (inorganic) 7439-92-1 20040708 Jul-08-2004 Yes None None
332 Libby Amphibole Asbestos 1318-09-8 20141208 Dec-08-2014 No Respiratory
9 x 10 -5 fiber/cc Respiratory
333 d-Limonene 5989-27-5 19931201 Dec-01-1993 Yes None None pesticide
334 Linuron 330-55-2 19890801 Aug-01-1989 Yes Hematologic
2 x 10 -3 mg/kg-day None pesticide archive
335 Londax 83055-99-6 19880907 Sep-07-1988 Yes Hepatic
2 x 10 -1 mg/kg-day None pesticide
336 Malathion 121-75-5 19870930 Sep-30-1987 Yes Nervous
2 x 10 -2 mg/kg-day None pesticide
337 Maleic anhydride 108-31-6 19880822 Aug-22-1988 Yes Urinary
1 x 10 -1 mg/kg-day None
338 Maleic hydrazide 123-33-1 19870331 Mar-31-1987 Yes Urinary
5 x 10 -1 mg/kg-day None pesticide
339 Maneb 12427-38-2 19880907 Sep-07-1988 Yes Endocrine
5 x 10 -3 mg/kg-day None pesticide
340 Manganese 7439-96-5 19951101 Nov-01-1995 Yes Nervous
1.4 x 10 -1 mg/kg-day 5 x 10 -5 mg/m3 None
341 Mepiquat chloride 24307-26-4 19880822 Aug-22-1988 Yes
Hematologic
Nervous
3 x 10 -2 mg/kg-day None pesticide
342 Mercuric chloride (HgCl2) 7487-94-7 19950501 May-01-1995 Yes
Immune
Urinary
3 x 10 -4 mg/kg-day None
343 Mercury, elemental 7439-97-6 19950601 Jun-01-1995 Yes Nervous
3 x 10 -4 mg/m3 None
344 Merphos 150-50-5 19921101 Nov-01-1992 Yes Nervous
3 x 10 -5 mg/kg-day None pesticide
345 Merphos oxide 78-48-8 19921101 Nov-01-1992 Yes Nervous
3 x 10 -5 mg/kg-day None pesticide archive
346 Metalaxyl 57837-19-1 19870131 Jan-31-1987 Yes Hepatic
6 x 10 -2 mg/kg-day None pesticide
347 Methacrylonitrile 126-98-7 19880907 Sep-07-1988 Yes Hepatic
1 x 10 -4 mg/kg-day None
348 Methamidophos 10265-92-6 19870930 Sep-30-1987 Yes Nervous
5 x 10 -5 mg/kg-day None pesticide
349 Methanol 67-56-1 20130930 Sep-30-2013 No
Developmental
Nervous
2 mg/kg-day 2 x 10 1 mg/m3 None
350 Methidathion 950-37-8 19890501 May-01-1989 No Hepatic
1 x 10 -3 mg/kg-day None pesticide archive
351 Methomyl 16752-77-5 19870131 Jan-31-1987 Yes
Immune
Urinary
2.5 x 10 -2 mg/kg-day None pesticide
352 Methoxychlor 72-43-5 19931201 Dec-01-1993 Yes Developmental
5 x 10 -3 mg/kg-day None pesticide
353 2-Methoxyethanol 109-86-4 19910501 May-01-1991 Yes Reproductive
2 x 10 -2 mg/m3 None
354 Methyl acrylate 96-33-3 19901201 Dec-01-1990 Yes None None
355 Methyl chloride 74-87-3 20010717 Jul-17-2001 Yes Nervous
9 x 10 -2 mg/m3 None
356 Methyl chlorocarbonate 79-22-1 19890501 May-01-1989 No None None archive
357 Methyl ethyl ketone (MEK) 78-93-3 20030926 Sep-26-2003 No
Developmental
Musculoskeletal
6 x 10 -1 mg/kg-day 5 mg/m3 None
358 Methyl iodide 74-88-4 19920901 Sep-01-1992 No None None archive
359 Methyl isobutyl ketone (MIBK) 108-10-1 20030425 Apr-25-2003 No
Developmental
Musculoskeletal
3 mg/m3 None
360 Methyl isocyanate 624-83-9 19910301 Mar-01-1991 Yes None None archive
361 Methyl methacrylate 80-62-6 19980302 Mar-02-1998 No
Nervous
Respiratory
1.4 mg/kg-day 7 x 10 -1 mg/m3 None
362 Methyl parathion 298-00-0 19870331 Mar-31-1987 No
Hematologic
Nervous
2.5 x 10 -4 mg/kg-day None pesticide
363 Methyl tert-butyl ether (MTBE) 1634-04-4 19930901 Sep-01-1993 No
Hepatic
Ocular
Urinary
3 mg/m3 None
364 4-(2-Methyl-4-chlorophenoxy) butyric acid (MCPB) 94-81-5 19880926 Sep-26-1988 Yes
Hepatic
Reproductive
Urinary
1 x 10 -2 mg/kg-day None pesticide archive
365 2-(2-Methyl-4-chlorophenoxy)propionic acid (MCPP) 93-65-2 19890101 Jan-01-1989 Yes Urinary
1 x 10 -3 mg/kg-day None pesticide
366 2-Methyl-4-chlorophenoxyacetic acid (MCPA) 94-74-6 19870828 Aug-28-1987 Yes
Hepatic
Urinary
5 x 10 -4 mg/kg-day None pesticide
367 Methylene Diphenyl Diisocyanate (monomeric MDI) and polymeric MDI (PMDI) 101-68-8 19980207 Feb-07-1998 Yes
Nervous
Respiratory
6 x 10 -4 mg/m3 None
368 4,4'-Methylene bis(N,N'-dimethyl)aniline 101-61-1 19890801 Aug-01-1989 No None Endocrine
369 Methylmercury (MeHg) 22967-92-6 20010727 Jul-27-2001 Yes
Developmental
Nervous
1 x 10 -4 mg/kg-day None
370 2-Methylnaphthalene 91-57-6 20031222 Dec-22-2003 No Respiratory
4 x 10 -3 mg/kg-day None
371 2-Methylphenol 95-48-7 19920401 Apr-01-1992 Yes Nervous
5 x 10 -2 mg/kg-day None
372 3-Methylphenol 108-39-4 19920401 Apr-01-1992 Yes Nervous
5 x 10 -2 mg/kg-day None
373 4-Methylphenol 106-44-5 19920401 Apr-01-1992 Yes None None
374 Metolachlor 51218-45-2 19901001 Oct-01-1990 No Reproductive
1.5 x 10 -1 mg/kg-day None pesticide
375 Metribuzin 21087-64-9 19931201 Dec-01-1993 Yes
Hepatic
Urinary
2.5 x 10 -2 mg/kg-day None pesticide
376 Mirex 2385-85-5 19921001 Oct-01-1992 No
Endocrine
Hepatic
2 x 10 -4 mg/kg-day None pesticide
377 Molinate 2212-67-1 19880926 Sep-26-1988 Yes Reproductive
2 x 10 -3 mg/kg-day None pesticide
378 Molybdenum 7439-98-7 19921101 Nov-01-1992 Yes Urinary
5 x 10 -3 mg/kg-day None
379 Monochloramine 10599-90-3 19940301 Mar-01-1994 No None 1 x 10 -1 mg/kg-day None
380 Naled 300-76-5 19870331 Mar-31-1987 Yes Nervous
2 x 10 -3 mg/kg-day None pesticide
381 Naphthalene 91-20-3 19980917 Sep-17-1998 No
Nervous
Respiratory
2 x 10 -2 mg/kg-day 3 x 10 -3 mg/m3 None
382 Napropamide 15299-99-7 19890701 Jul-01-1989 Yes Reproductive
1 x 10 -1 mg/kg-day None pesticide archive
383 Nickel carbonyl 13463-39-3 19870930 Sep-30-1987 Yes None None
384 Nickel refinery dust None 19870930 Sep-30-1987 No None Respiratory
385 Nickel subsulfide 12035-72-2 19870930 Sep-30-1987 Yes None Respiratory
386 Nickel, soluble salts Various 19940801 Aug-01-1994 No None 2 x 10 -2 mg/kg-day None
387 Nitrapyrin 1929-82-4 19920701 Jul-01-1992 Yes None None pesticide archive
388 Nitrate 14797-55-8 19910501 May-01-1991 Yes Hematologic
1.6 mg/kg-day None
389 Nitric oxide 10102-43-9 19940901 Sep-01-1994 Yes None None
390 Nitrite 14797-65-0 19870131 Jan-31-1987 Yes Hematologic
1 x 10 -1 mg/kg-day None
391 Nitrobenzene 98-95-3 20090206 Feb-06-2009 No
Hematologic
Nervous
Respiratory
2 x 10 -3 mg/kg-day 9 x 10 -3 mg/m3
Endocrine
Hepatic
Urinary
392 Nitrogen dioxide 10102-44-0 19940901 Sep-01-1994 Yes None None
393 Nitroguanidine 556-88-7 19900901 Sep-01-1990 Yes Developmental
1 x 10 -1 mg/kg-day None
394 p-Nitrophenol 100-02-7 19911001 Oct-01-1991 Yes None None pesticide archive
395 2-Nitropropane 79-46-9 19910301 Mar-01-1991 Yes Hepatic
2 x 10 -2 mg/m3 None
396 N-Nitroso-N-methylethylamine 10595-95-6 19880301 Mar-01-1988 Yes None Hepatic
397 N-Nitroso-di-n-butylamine 924-16-3 19870131 Jan-31-1987 Yes None
Gastrointestinal
Urinary
398 N-Nitrosodi-N-propylamine 621-64-7 19870331 Mar-31-1987 Yes None Hepatic
399 N-Nitrosodiethanolamine 1116-54-7 19870930 Sep-30-1987 Yes None Hepatic
400 N-Nitrosodiethylamine 55-18-5 19870131 Jan-31-1987 Yes None Hepatic
401 N-Nitrosodimethylamine 62-75-9 19870131 Jan-31-1987 Yes None Hepatic
402 N-Nitrosodiphenylamine 86-30-6 19870331 Mar-31-1987 Yes None Urinary
403 N-Nitrosopyrrolidine 930-55-2 19870131 Jan-31-1987 Yes None Hepatic
404 Nonabromodiphenyl ether 63936-56-1 19900801 Aug-01-1990 Yes None None
405 Norflurazon 27314-13-2 19870131 Jan-31-1987 Yes
Endocrine
Hepatic
4 x 10 -2 mg/kg-day None pesticide archive
406 NuStar 85509-19-9 19880926 Sep-26-1988 Yes Hepatic
7 x 10 -4 mg/kg-day None pesticide archive
407 Octabromodiphenyl ether 32536-52-0 19900801 Aug-01-1990 Yes Hepatic
3 x 10 -3 mg/kg-day None
408 Octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX) 2691-41-0 19890301 Mar-01-1989 Yes Hepatic
5 x 10 -2 mg/kg-day None
409 Oryzalin 19044-88-3 19890701 Jul-01-1989 Yes
Endocrine
Hepatic
Urinary
5 x 10 -2 mg/kg-day None pesticide archive
410 Oxadiazon 19666-30-9 19870930 Sep-30-1987 Yes
Hematologic
Hepatic
5 x 10 -3 mg/kg-day None pesticide
411 Oxamyl 23135-22-0 19870331 Mar-31-1987 Yes None 2.5 x 10 -2 mg/kg-day None pesticide
412 Oxyfluorfen 42874-03-3 19870131 Jan-31-1987 Yes Hepatic
3 x 10 -3 mg/kg-day None pesticide archive
413 Paclobutrazol 76738-62-0 19870331 Mar-31-1987 Yes Hepatic
1.3 x 10 -2 mg/kg-day None pesticide
414 Paraquat 1910-42-5 19880822 Aug-22-1988 Yes Respiratory
4.5 x 10 -3 mg/kg-day None pesticide
415 Parathion 56-38-2 19880822 Aug-22-1988 Yes None None pesticide
416 Pendimethalin 40487-42-1 19880630 Jun-30-1988 No Hepatic
4 x 10 -2 mg/kg-day None pesticide archive
417 2,2',4,4',5-Pentabromodiphenyl ether (BDE-99) 60348-60-9 20080630 Jun-30-2008 No Nervous
1 x 10 -4 mg/kg-day None
418 Pentabromodiphenyl ether 32534-81-9 19900801 Aug-01-1990 Yes Hepatic
2 x 10 -3 mg/kg-day None
419 Pentachlorobenzene 608-93-5 19921101 Nov-01-1992 Yes
Hepatic
Urinary
8 x 10 -4 mg/kg-day None
420 Pentachlorocyclopentadiene 25329-35-5 19900301 Mar-01-1990 No None None
421 Pentachloronitrobenzene (PCNB) 82-68-8 19870930 Sep-30-1987 Yes Hepatic
3 x 10 -3 mg/kg-day None pesticide
422 Pentachlorophenol 87-86-5 20100930 Sep-30-2010 No Hepatic
5 x 10 -3 mg/kg-day
Endocrine
Hepatic
423 Pentafluoroethane 354-33-6 19931201 Dec-01-1993 Yes None None
424 Perchlorate (ClO4) and Perchlorate Salts 7790-98-9 20050218 Feb-18-2005 No Endocrine
7 x 10 -4 mg/kg-day None
425 Perfluorobutanoic Acid (PFBA) 375-22-4 20221222 Dec-22-2022 No
Developmental
Endocrine
Hepatic
1 x 10 -3 mg/kg-day None
426 Perfluorodecanoic Acid (PFDA) 335-76-2 20240715 Jul-15-2024 No
Developmental
Immune
None
427 Perfluorohexanesulfonic Acid (PFHxS) 355-46-4 No None None
428 Perfluorohexanoic Acid (PFHxA) 307-24-4 20230410 Apr-10-2023 No
Developmental
Endocrine
Hematologic
Hepatic
5 x 10 -4 mg/kg-day 5 x 10 -4 mg/kg-day None
429 Permethrin 52645-53-1 19870331 Mar-31-1987 Yes Hepatic
5 x 10 -2 mg/kg-day None pesticide
430 Phenanthrene 85-01-8 19901201 Dec-01-1990 No None None
431 Phenmedipham 13684-63-4 19900601 Jun-01-1990 Yes None 2.5 x 10 -1 mg/kg-day None pesticide archive
432 Phenol 108-95-2 20020930 Sep-30-2002 Yes None 3 x 10 -1 mg/kg-day None
433 m-Phenylenediamine 108-45-2 19870131 Jan-31-1987 Yes Hepatic
6 x 10 -3 mg/kg-day None
434 Phenylmercuric acetate 62-38-4 19870131 Jan-31-1987 Yes Urinary
8 x 10 -5 mg/kg-day None
435 Phosalone 2310-17-0 19881201 Dec-01-1988 No None None pesticide archive
436 Phosgene 75-44-5 20060131 Jan-31-2006 No Respiratory
3 x 10 -4 mg/m3 None
437 Phosmet 732-11-6 19870131 Jan-31-1987 Yes
Hepatic
Nervous
2 x 10 -2 mg/kg-day None pesticide
438 Phosphine 7803-51-2 19950701 Jul-01-1995 Yes None 3 x 10 -4 mg/kg-day 3 x 10 -4 mg/m3 None
439 Phosphoric acid 7664-38-2 19950801 Aug-01-1995 No Respiratory
1 x 10 -2 mg/m3 None
440 Phthalic anhydride 85-44-9 19880907 Sep-07-1988 Yes
Respiratory
Urinary
2 mg/kg-day None
441 Picloram 1918-02-1 19870930 Sep-30-1987 Yes Hepatic
7 x 10 -2 mg/kg-day None pesticide
442 Pirimiphos-methyl 29232-93-7 19870930 Sep-30-1987 Yes Nervous
1 x 10 -2 mg/kg-day None pesticide archive
443 Polychlorinated Biphenyls (PCBs) 1336-36-3 19961001 Oct-01-1996 No None Hepatic
444 Polycyclic aromatic hydrocarbon (PAH) mixtures Various No None None
445 Potassium cyanide 151-50-8 20100928 Sep-28-2010 Yes Reproductive
2 x 10 -3 mg/kg-day None
446 Potassium silver cyanide 506-61-6 20100928 Sep-28-2010 Yes Reproductive
5 x 10 -3 mg/kg-day None
447 Prochloraz 67747-09-5 19891001 Oct-01-1989 Yes Hepatic
9 x 10 -3 mg/kg-day Hepatic
pesticide
448 Prometon 1610-18-0 19870131 Jan-31-1987 Yes None 1.5 x 10 -2 mg/kg-day None pesticide
449 Prometryn 7287-19-6 19870930 Sep-30-1987 Yes
Hematologic
Hepatic
Immune
Urinary
4 x 10 -3 mg/kg-day None pesticide archive
450 Pronamide 23950-58-5 19870131 Jan-31-1987 Yes None 7.5 x 10 -2 mg/kg-day None pesticide
451 Propachlor 1918-16-7 19870131 Jan-31-1987 No Hepatic
1.3 x 10 -2 mg/kg-day None pesticide
452 Propanil 709-98-8 19880301 Mar-01-1988 Yes Immune
5 x 10 -3 mg/kg-day None pesticide
453 Propargite 2312-35-8 19900501 May-01-1990 Yes
Developmental
Musculoskeletal
2 x 10 -2 mg/kg-day None pesticide archive
454 Propargyl alcohol 107-19-7 19901101 Nov-01-1990 Yes
Hepatic
Urinary
2 x 10 -3 mg/kg-day None
455 Propazine 139-40-2 19870828 Aug-28-1987 Yes None 2 x 10 -2 mg/kg-day None pesticide
456 Propham 122-42-9 19870930 Sep-30-1987 Yes
Immune
Nervous
2 x 10 -2 mg/kg-day None pesticide
457 Propiconazole 60207-90-1 19880822 Aug-22-1988 Yes Gastrointestinal
1.3 x 10 -2 mg/kg-day None pesticide archive
458 beta-Propiolactone 57-57-8 19910701 Jul-01-1991 Yes None None archive
459 Propionaldehyde 123-38-6 20080930 Sep-30-2008 No
Nervous
Respiratory
8 x 10 -3 mg/m3 None
460 Propylene glycol 57-55-6 19910601 Jun-01-1991 Yes None None pesticide archive
461 Propylene glycol monoethyl ether 52125-53-8 19910601 Jun-01-1991 No None None archive
462 Propylene glycol monomethyl ether (PGME) 107-98-2 19910701 Jul-01-1991 Yes Nervous
2 mg/m3 None
463 Propylene oxide 75-56-9 19901101 Nov-01-1990 Yes Respiratory
3 x 10 -2 mg/m3
Gastrointestinal
Respiratory
464 Propyleneimine 75-55-8 19920101 Jan-01-1992 Yes None None archive
465 Pursuit 81335-77-5 19900101 Jan-01-1990 Yes Hematologic
2.5 x 10 -1 mg/kg-day None pesticide archive
466 Pydrin 51630-58-1 19870331 Mar-31-1987 Yes Nervous
2.5 x 10 -2 mg/kg-day None pesticide
467 Pyrene 129-00-0 19900901 Sep-01-1990 No Urinary
3 x 10 -2 mg/kg-day None
468 Pyridine 110-86-1 19870930 Sep-30-1987 Yes Hepatic
1 x 10 -3 mg/kg-day None
469 Quinalphos 13593-03-8 19870331 Mar-31-1987 Yes None 5 x 10 -4 mg/kg-day None pesticide
470 Quinoline 91-22-5 20010927 Sep-27-2001 No None Hepatic
471 Quinone 106-51-4 19901001 Oct-01-1990 Yes None None archive
472 Radium 226,228 Various 19890101 Jan-01-1989 Yes None None archive
473 Radon 222 14859-67-7 19890701 Jul-01-1989 Yes None None archive
474 Refractory ceramic fibers None 19920901 Sep-01-1992 No None None
475 Resmethrin 10453-86-8 19880926 Sep-26-1988 Yes Reproductive
3 x 10 -2 mg/kg-day None pesticide
476 Rotenone 83-79-4 19880907 Sep-07-1988 Yes Developmental
4 x 10 -3 mg/kg-day None pesticide
477 Savey 78587-05-0 19880926 Sep-26-1988 Yes
Endocrine
Hematologic
2.5 x 10 -2 mg/kg-day None pesticide
478 Selenious acid 7783-00-8 19910601 Jun-01-1991 No
Dermal
Hematologic
Nervous
5 x 10 -3 mg/kg-day None
479 Selenium and Compounds 7782-49-2 19910601 Jun-01-1991 Yes
Dermal
Hematologic
Nervous
5 x 10 -3 mg/kg-day None
480 Selenium sulfide 7446-34-6 19910301 Mar-01-1991 Yes None None
481 Selenourea 630-10-4 19910501 May-01-1991 No None None archive
482 Sethoxydim 74051-80-2 19891101 Nov-01-1989 Yes Hematologic
9 x 10 -2 mg/kg-day None pesticide archive
483 Silver 7440-22-4 19911201 Dec-01-1991 Yes Dermal
5 x 10 -3 mg/kg-day None
484 Silver cyanide 506-64-9 19870131 Jan-31-1987 No
Endocrine
Nervous
1 x 10 -1 mg/kg-day None
485 Simazine 122-34-9 19930901 Sep-01-1993 Yes Hematologic
5 x 10 -3 mg/kg-day None pesticide
486 Sodium azide 26628-22-8 19870331 Mar-31-1987 Yes None 4 x 10 -3 mg/kg-day None
487 Sodium cyanide 143-33-9 20100928 Sep-28-2010 Yes Reproductive
1 x 10 -3 mg/kg-day None
488 Sodium diethyldithiocarbamate 148-18-5 19870131 Jan-31-1987 Yes None 3 x 10 -2 mg/kg-day None
489 Sodium fluoroacetate 62-74-8 19910501 May-01-1991 Yes
Cardiovascular
Reproductive
2 x 10 -5 mg/kg-day None pesticide
490 Strontium 7440-24-6 19921001 Oct-01-1992 Yes Musculoskeletal
6 x 10 -1 mg/kg-day None
491 Strychnine 57-24-9 19870131 Jan-31-1987 Yes None 3 x 10 -4 mg/kg-day None pesticide
492 Styrene 100-42-5 19921101 Nov-01-1992 No
Hematologic
Hepatic
Nervous
2 x 10 -1 mg/kg-day 1 mg/m3 None
493 Systhane 88671-89-0 19880926 Sep-26-1988 Yes Reproductive
2.5 x 10 -2 mg/kg-day None pesticide
494 Tebuthiuron 34014-18-1 19880822 Aug-22-1988 Yes None 7 x 10 -2 mg/kg-day None pesticide
495 Terbacil 5902-51-2 19870131 Jan-31-1987 Yes
Endocrine
Hepatic
1.3 x 10 -2 mg/kg-day None pesticide
496 Terbutryn 886-50-0 19880926 Sep-26-1988 Yes Hematologic
1 x 10 -3 mg/kg-day None pesticide
497 2,2',4,4'-Tetrabromodiphenyl ether (BDE-47) 5436-43-1 20080630 Jun-30-2008 No Nervous
1 x 10 -4 mg/kg-day None
498 Tetrabromodiphenyl ether 40088-47-9 19900801 Aug-01-1990 Yes None None
499 1,2,4,5-Tetrachlorobenzene 95-94-3 19870131 Jan-31-1987 Yes Urinary
3 x 10 -4 mg/kg-day None
500 Tetrachlorocyclopentadiene 695-77-2 19900301 Mar-01-1990 No None None
501 2,3,7,8-Tetrachlorodibenzo-p-dioxin 1746-01-6 20120217 Feb-17-2012 No
Developmental
Endocrine
Reproductive
7 x 10 -10 mg/kg-day None
502 1,1,1,2-Tetrachloroethane 630-20-6 19890301 Mar-01-1989 No
Hepatic
Urinary
3 x 10 -2 mg/kg-day Hepatic
503 1,1,2,2-Tetrachloroethane 79-34-5 20100930 Sep-30-2010 Yes Hepatic
Hepatic
504 Tetrachloroethylene (Perchloroethylene) 127-18-4 20120210 Feb-10-2012 No
Nervous
Ocular
6 x 10 -3 mg/kg-day 4 x 10 -2 mg/m3 Hepatic
505 2,3,4,6-Tetrachlorophenol 58-90-2 19880301 Mar-01-1988 Yes Hepatic
3 x 10 -2 mg/kg-day None
506 Tetrachlorovinphos 961-11-5 19870331 Mar-31-1987 Yes
Hepatic
Nervous
Urinary
3 x 10 -2 mg/kg-day None pesticide
507 Tetraethyl lead 78-00-2 19870131 Jan-31-1987 Yes
Hepatic
Immune
1 x 10 -7 mg/kg-day None
508 Tetraethyldithiopyrophosphate 3689-24-5 19880907 Sep-07-1988 Yes Nervous
5 x 10 -4 mg/kg-day None
509 1,1,1,2-Tetrafluoroethane 811-97-2 19950801 Aug-01-1995 Yes Reproductive
8 x 10 1 mg/m3 None
510 Tetrahydrofuran 109-99-9 20120221 Feb-21-2012 No
Developmental
Hepatic
Nervous
9 x 10 -1 mg/kg-day 2 mg/m3 None
511 Thallium (I), soluble salts Various 20090930 Sep-30-2009 No None None
512 Thallium acetate 563-68-8 20090930 Sep-30-2009 Yes None None
513 Thallium carbonate 6533-73-9 20090930 Sep-30-2009 Yes None None
514 Thallium chloride 7791-12-0 20090930 Sep-30-2009 Yes None None
515 Thallium nitrate 10102-45-1 20090930 Sep-30-2009 Yes None None
516 Thallium oxide 1314-32-5 20090930 Sep-30-2009 Yes None None
517 Thallium selenite 12039-52-0 20090930 Sep-30-2009 Yes None None
518 Thallium(I) sulfate 7446-18-6 20090930 Sep-30-2009 Yes None None
519 Thiobencarb 28249-77-6 19870930 Sep-30-1987 Yes Urinary
1 x 10 -2 mg/kg-day None pesticide
520 Thiophanate-methyl 23564-05-8 19870131 Jan-31-1987 Yes
Endocrine
Reproductive
8 x 10 -2 mg/kg-day None pesticide archive
521 Thiram 137-26-8 19870930 Sep-30-1987 Yes Nervous
5 x 10 -3 mg/kg-day None pesticide archive
522 Toluene 108-88-3 20050923 Sep-23-2005 No
Nervous
Urinary
8 x 10 -2 mg/kg-day 5 mg/m3 None
523 2,4-/2,6-Toluene diisocyanate mixture (TDI) 26471-62-5 19950901 Sep-01-1995 Yes Respiratory
7 x 10 -5 mg/m3 None
524 Toxaphene 8001-35-2 19880822 Aug-22-1988 Yes None Hepatic
pesticide
525 Tralomethrin 66841-25-6 19890701 Jul-01-1989 Yes None 7.5 x 10 -3 mg/kg-day None pesticide
526 Triallate 2303-17-5 19870331 Mar-31-1987 No Hepatic
1.3 x 10 -2 mg/kg-day None pesticide archive
527 Triasulfuron 82097-50-5 19910101 Jan-01-1991 Yes Hepatic
1 x 10 -2 mg/kg-day None pesticide
528 1,2,4-Tribromobenzene 615-54-3 19870331 Mar-31-1987 No Hepatic
5 x 10 -3 mg/kg-day None
529 Tribromochloromethane 594-15-0 19910301 Mar-01-1991 No None None
530 Tribromodiphenyl ether 49690-94-0 19900801 Aug-01-1990 Yes None None
531 Tributyltin oxide (TBTO) 56-35-9 19970901 Sep-01-1997 Yes Immune
3 x 10 -4 mg/kg-day None pesticide
532 1,1,2-Trichloro-1,2,2-trifluoroethane (CFC-113) 76-13-1 19870406 Apr-06-1987 Yes Nervous
3 x 10 1 mg/kg-day None
533 Trichloroacetic acid 76-03-9 20110930 Sep-30-2011 Yes Hepatic
2 x 10 -2 mg/kg-day Hepatic
534 1,2,4-Trichlorobenzene 120-82-1 19920501 May-01-1992 Yes Endocrine
1 x 10 -2 mg/kg-day None
535 Trichlorocyclopentadiene 77323-84-3 19900301 Mar-01-1990 No None None
536 1,1,1-Trichloroethane 71-55-6 20070928 Sep-28-2007 Yes
Hepatic
Nervous
2 mg/kg-day 7 mg/kg-day 5 mg/m3 5 mg/m3 None
537 1,1,2-Trichloroethane 79-00-5 19880926 Sep-26-1988 Yes
Hematologic
Immune
4 x 10 -3 mg/kg-day Hepatic
538 Trichloroethylene 79-01-6 20110928 Sep-28-2011 No
Developmental
Immune
5 x 10 -4 mg/kg-day 2 x 10 -3 mg/m3
Hematologic
Hepatic
Urinary
539 Trichlorofluoromethane 75-69-4 19870131 Jan-31-1987 Yes
Cardiovascular
Respiratory
3 x 10 -1 mg/kg-day None
540 2,4,5-Trichlorophenol 95-95-4 19910701 Jul-01-1991 Yes
Hepatic
Urinary
1 x 10 -1 mg/kg-day None
541 2,4,6-Trichlorophenol 88-06-2 19910701 Jul-01-1991 Yes None Hematologic
542 2(2,4,5-Trichlorophenoxy) propionic acid (2,4,5-TP) 93-72-1 19880907 Sep-07-1988 Yes Hepatic
8 x 10 -3 mg/kg-day None
543 2,4,5-Trichlorophenoxyacetic acid (2,4,5-T) 93-76-5 19880907 Sep-07-1988 Yes Urinary
1 x 10 -2 mg/kg-day None
544 1,1,2-Trichloropropane 598-77-6 19880926 Sep-26-1988 No
Endocrine
Hepatic
Urinary
5 x 10 -3 mg/kg-day None
545 1,2,3-Trichloropropane 96-18-4 20090930 Sep-30-2009 Yes
Hepatic
Respiratory
4 x 10 -3 mg/kg-day 3 x 10 -4 mg/m3
Gastrointestinal
Hepatic
Ocular
Reproductive
546 Tricresol 1319-77-3 19920401 Apr-01-1992 Yes None None archive
547 Tridiphane 58138-08-2 19870131 Jan-31-1987 Yes Reproductive
3 x 10 -3 mg/kg-day None pesticide
548 Triethylamine 121-44-8 19910401 Apr-01-1991 Yes Respiratory
7 x 10 -3 mg/m3 None
549 Triethylene glycol monobutyl ether 143-22-6 19940901 Sep-01-1994 No None None
550 Triethylene glycol monoethyl ether 112-50-5 19940901 Sep-01-1994 No None None
551 Trifluralin 1582-09-8 19890701 Jul-01-1989 Yes
Hematologic
Hepatic
7.5 x 10 -3 mg/kg-day
Endocrine
Urinary
pesticide
552 1,2,3-Trimethylbenzene 526-73-8 20160909 Sep-09-2016 No
Hematologic
Nervous
Respiratory
1 x 10 -2 mg/kg-day 4 x 10 -2 mg/kg-day 6 x 10 -2 mg/m3 2 x 10 -1 mg/m3 None
553 1,2,4-Trimethylbenzene 95-63-6 20160909 Sep-09-2016 No
Developmental
Hematologic
Nervous
Respiratory
1 x 10 -2 mg/kg-day 4 x 10 -2 mg/kg-day 6 x 10 -2 mg/m3 2 x 10 -1 mg/m3 None
554 1,3,5-Trimethylbenzene 108-67-8 20160909 Sep-09-2016 No
Developmental
Nervous
1 x 10 -2 mg/kg-day 4 x 10 -2 mg/kg-day 6 x 10 -2 mg/m3 2 x 10 -1 mg/m3 None
555 2,2,4-Trimethylpentane 540-84-1 20070731 Jul-31-2007 Yes None None
556 1,3,5-Trinitrobenzene 99-35-4 19971001 Oct-01-1997 Yes Hematologic
3 x 10 -2 mg/kg-day None
557 2,4,6-Trinitrotoluene (TNT) 118-96-7 19890601 Jun-01-1989 Yes Hepatic
5 x 10 -4 mg/kg-day Urinary
558 Uranium, soluble salts Various 19891001 Oct-01-1989 Yes Urinary
3 x 10 -3 mg/kg-day None
559 Urea 57-13-6 20110713 Jul-13-2011 No None None
560 Vanadium pentoxide 1314-62-1 19880630 Jun-30-1988 Yes Dermal
9 x 10 -3 mg/kg-day None
561 Vernam 1929-77-7 19870331 Mar-31-1987 No None 1 x 10 -3 mg/kg-day None pesticide
562 Vinclozolin 50471-44-8 19870131 Jan-31-1987 Yes
Endocrine
Urinary
2.5 x 10 -2 mg/kg-day None pesticide archive
563 Vinyl acetate 108-05-4 19901001 Oct-01-1990 No
Nervous
Respiratory
2 x 10 -1 mg/m3 None
564 Vinyl bromide 593-60-2 19930501 May-01-1993 Yes Hepatic
3 x 10 -3 mg/m3 None
565 Vinyl chloride 75-01-4 20000807 Aug-07-2000 Yes Hepatic
3 x 10 -3 mg/kg-day 1 x 10 -1 mg/m3 Hepatic
566 Warfarin 81-81-2 19870331 Mar-31-1987 Yes Hematologic
3 x 10 -4 mg/kg-day None pesticide
567 White phosphorus 7723-14-0 19901201 Dec-01-1990 Yes
Dermal
Reproductive
2 x 10 -5 mg/kg-day None
568 Xylenes 1330-20-7 20030221 Feb-21-2003 No Nervous
2 x 10 -1 mg/kg-day 1 x 10 -1 mg/m3 None
569 Zinc and Compounds 7440-66-6 20050803 Aug-03-2005 No
Hematologic
Immune
3 x 10 -1 mg/kg-day None
570 Zinc cyanide 557-21-1 19870131 Jan-31-1987 Yes
Endocrine
Nervous
5 x 10 -2 mg/kg-day None
571 Zinc phosphide 1314-84-7 19870331 Mar-31-1987 Yes None 3 x 10 -4 mg/kg-day None pesticide
572 Zineb 12122-67-7 19870331 Mar-31-1987 Yes Endocrine
5 x 10 -2 mg/kg-day None pesticide

This page provides a list of IRIS assessments in development for which draft materials have been released to the public, along with the current step in assessment development for each chemical. See the IRIS Process page for a description of each step, and the Quick Check on the chemical landing pages for a visualization of where each assessments is in the IRIS development process. Assessments in development are not included in the IRIS database and are not captured by IRIS Advanced Search. Use the table below to access these assessments.   

  Chemical Name CASRN IRIS Progress Step Draft Documents
1 Arsenic, Inorganic (iA) 7440-38-2 Step 4
2 Chloroform 67-66-3 Step 3
3 Cobalt and Cobalt Compounds 1307-96-6 Step 1
4 Ethylbenzene 100-41-4 Step 1
5 Mercury Salts, Inorganic Various Step 1
6 Methylmercury (MeHg) 22967-92-6 Step 1
7 Naphthalene 91-20-3 Step 1
8 Nitrate 14797-55-8 Step 1
9 Nitrite 14797-65-0 Step 1
10 Perfluorohexanesulfonic Acid (PFHxS) 355-46-4 Step 5
11 Perfluorononanoic Acid (PFNA) 375-95-1 Step 5
12 Polychlorinated Biphenyls (PCBs) 1336-36-3 Step 1
13 Uranium, natural 7440-61-1 Step 1
14 Vanadium and Compounds (Oral) Various Step 1
15 Vanadium and Compounds (Inhalation) Various Step 1

This page provides a list of final IRIS assessments that have been archived and are no longer included in the IRIS database.   

  Chemical Name CASRN Last Significant Revision* Archive Date
1 Acephate 30560-19-1 19890501 05/01/1989 20160715 07/15/2016
2 Amdro 67485-29-4 19870930 09/30/1987 20160715 07/15/2016
3 ortho-Anisidine 90-04-0 19911001 10/01/1991 20181219 12/19/2018
4 Asulam 3337-71-1 19880630 06/30/1988 20160715 07/15/2016
5 Barium cyanide 542-62-1 19910301 03/01/1991 20181219 12/19/2018
6 Bayleton 43121-43-3 19880301 03/01/1988 20160715 07/15/2016
7 Benefin 1861-40-1 19870331 03/31/1987 20160715 07/15/2016
8 Bidrin 141-66-2 19870930 09/30/1987 20160715 07/15/2016
9 Bromoxynil 1689-84-5 19880630 06/30/1988 20160715 07/15/2016
10 Bromoxynil octanoate 1689-99-2 19880907 09/07/1988 20160715 07/15/2016
11 Carbonyl sulfide 463-58-1 19911101 11/01/1991 20181219 12/19/2018
12 Chlorimuron-ethyl 90982-32-4 19891101 11/01/1989 20160715 07/15/2016
13 Chlorpropham 101-21-3 19980630 06/30/1998 20160715 07/15/2016
14 Chlorpyrifos 2921-88-2 20110324 03/24/2011 20180314 03/14/2018
15 Chlorsulfuron 64902-72-3 19870131 01/31/1987 20160715 07/15/2016
16 Cyanazine 21725-46-2 19920701 07/01/1992 20181210 12/10/2018
17 Cyhalothrin/Karate 68085-85-8 19880630 06/30/1988 20160715 07/15/2016
18 Cypermethrin 52315-07-8 19890301 03/01/1989 20160715 07/15/2016
19 Cyromazine 66215-27-8 19870930 09/30/1987 20160715 07/15/2016
20 Diazomethane 334-88-3 19911101 11/01/1991 20181219 12/19/2018
21 4-(2,4-Dichlorophenoxy)butyric acid (2,4-DB) 94-82-6 19870131 01/31/1987 20160715 07/15/2016
22 Dicofol 115-32-2 19920401 04/01/1992 20181210 12/10/2018
23 Diethyl sulfate 64-67-5 19911101 11/01/1991 20181219 12/19/2018
24 Difenzoquat 43222-48-6 19880822 08/22/1988 20160715 07/15/2016
25 Dimethipin 55290-64-7 19900501 05/01/1990 20160715 07/15/2016
26 Dimethoate 60-51-5 19880822 08/22/1988 20160715 07/15/2016
27 Dimethylamine 124-40-3 19910101 01/01/1991 20181219 12/19/2018
28 3,3-Dimethylbenzidine 119-93-7 19910701 07/01/1991 20181219 12/19/2018
29 Diphenylamine 122-39-4 19870131 01/31/1987 20160715 07/15/2016
30 Dodine 2439-10-3 19870930 09/30/1987 20160715 07/15/2016
31 Ethyl carbamate 51-79-6 19920401 04/01/1992 20181219 12/19/2018
32 S-Ethyl dipropylthiocarbamate (EPTC) 759-94-4 19870930 09/30/1987 20160715 07/15/2016
33 Ethyleneimine 151-56-4 19920401 04/01/1992 20181219 12/19/2018
34 Flurprimidol 56425-91-3 19890701 07/01/1989 20160715 07/15/2016
35 Flutolanil 66332-96-5 19890501 05/01/1989 20160715 07/15/2016
36 Folpet 133-07-3 19880822 08/22/1988 20160715 07/15/2016
37 Fomesafen 72178-02-0 19880822 08/22/1988 20160715 07/15/2016
38 Formic acid 64-18-6 19901201 12/01/1990 20181210 12/10/2018
39 Fosetyl-al 39148-24-8 19880822 08/22/1988 20160715 07/15/2016
40 Glufosinate-ammonium 77182-82-2 19870930 09/30/1987 20160715 07/15/2016
41 Harmony 79277-27-3 19880926 09/26/1988 20160715 07/15/2016
42 Hydroquinone 123-31-9 19901001 10/01/1990 20181219 12/19/2018
43 Imazalil 35554-44-0 19870331 03/31/1987 20160715 07/15/2016
44 Lactofen 77501-63-4 19880630 06/30/1988 20160715 07/15/2016
45 Linuron 330-55-2 19890801 08/01/1989 20160715 07/15/2016
46 Merphos oxide 78-48-8 19921101 11/01/1992 20160715 07/15/2016
47 Methidathion 950-37-8 19890501 05/01/1989 20160715 07/15/2016
48 Methyl chlorocarbonate 79-22-1 19890501 05/01/1989 20181219 12/19/2018
49 Methyl iodide 74-88-4 19920901 09/01/1992 20181210 12/10/2018
50 Methyl isocyanate 624-83-9 19910301 03/01/1991 20181219 12/19/2018
51 4-(2-Methyl-4-chlorophenoxy) butyric acid (MCPB) 94-81-5 19880926 09/26/1988 20160715 07/15/2016
52 Napropamide 15299-99-7 19890701 07/01/1989 20160715 07/15/2016
53 Nitrapyrin 1929-82-4 19920701 07/01/1992 20181210 12/10/2018
54 p-Nitrophenol 100-02-7 19911001 10/01/1991 20181210 12/10/2018
55 Norflurazon 27314-13-2 19870131 01/31/1987 20160715 07/15/2016
56 NuStar 85509-19-9 19880926 09/26/1988 20160715 07/15/2016
57 Oryzalin 19044-88-3 19890701 07/01/1989 20160715 07/15/2016
58 Oxyfluorfen 42874-03-3 19870131 01/31/1987 20160715 07/15/2016
59 Pendimethalin 40487-42-1 19880630 06/30/1988 20160715 07/15/2016
60 Phenmedipham 13684-63-4 19900601 06/01/1990 20160715 07/15/2016
61 Phosalone 2310-17-0 19881201 12/01/1988 20181210 12/10/2018
62 Pirimiphos-methyl 29232-93-7 19870930 09/30/1987 20160715 07/15/2016
63 Prometryn 7287-19-6 19870930 09/30/1987 20160715 07/15/2016
64 Propargite 2312-35-8 19900501 05/01/1990 20160715 07/15/2016
65 Propiconazole 60207-90-1 19880822 08/22/1988 20160715 07/15/2016
66 beta-Propiolactone 57-57-8 19910701 07/01/1991 20181219 12/19/2018
67 Propylene glycol 57-55-6 19910601 06/01/1991 20181210 12/10/2018
68 Propylene glycol monoethyl ether 52125-53-8 19910601 06/01/1991 20181219 12/19/2018
69 Propyleneimine 75-55-8 19920101 01/01/1992 20181219 12/19/2018
70 Pursuit 81335-77-5 19900101 01/01/1990 20160715 07/15/2016
71 Quinone 106-51-4 19901001 10/01/1990 20181219 12/19/2018
72 Radium 226,228 Various 19890101 01/01/1989 20181219 12/19/2018
73 Radon 222 14859-67-7 19890701 07/01/1989 20181219 12/19/2018
74 Selenourea 630-10-4 19910501 05/01/1991 20181219 12/19/2018
75 Sethoxydim 74051-80-2 19891101 11/01/1989 20160715 07/15/2016
76 Thiophanate-methyl 23564-05-8 19870131 01/31/1987 20160715 07/15/2016
77 Thiram 137-26-8 19870930 09/30/1987 20160715 07/15/2016
78 Triallate 2303-17-5 19870331 03/31/1987 20160715 07/15/2016
79 Tricresol 1319-77-3 19920401 04/01/1992 20181024 10/24/2018
80 Vinclozolin 50471-44-8 19870131 01/31/1987 20160715 07/15/2016