{"id":"https://openalex.org/W3131846890","doi":"https://doi.org/10.3389/fdgth.2021.640685","title":"Deep Multi-Modal Transfer Learning for Augmented Patient Acuity Assessment in the Intelligent ICU","display_name":"Deep Multi-Modal Transfer Learning for Augmented Patient Acuity Assessment in the Intelligent ICU","publication_year":2021,"publication_date":"2021-02-22","ids":{"openalex":"https://openalex.org/W3131846890","doi":"https://doi.org/10.3389/fdgth.2021.640685","mag":"3131846890","pmid":"https://pubmed.ncbi.nlm.nih.gov/33718920","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7954405"},"language":"en","primary_location":{"is_oa":true,"landing_page_url":"https://doi.org/10.3389/fdgth.2021.640685","pdf_url":"https://www.frontiersin.org/articles/10.3389/fdgth.2021.640685/pdf","source":{"id":"https://openalex.org/S4210170686","display_name":"Frontiers in Digital Health","issn_l":"2673-253X","issn":["2673-253X"],"is_oa":true,"is_in_doaj":true,"is_indexed_in_scopus":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true},"type":"article","type_crossref":"journal-article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fdgth.2021.640685/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019504069","display_name":"Benjamin Shickel","orcid":"https://orcid.org/0000-0002-5304-7027"},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"funder","lineage":["https://openalex.org/I33213144"]},{"id":"https://openalex.org/I4210104680","display_name":"Proteogenomics Research Institute for Systems Medicine","ror":"https://ror.org/01c44a921","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210104680"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Benjamin Shickel","raw_affiliation_strings":["Department of Computer and Information Science and Engineering, University of Florida, Gainesville, FL, United States","Precision and Intelligent Systems in Medicine (PRISMAP), University of Florida, Gainesville, FL, United States"],"affiliations":[{"raw_affiliation_string":"Precision and Intelligent Systems in Medicine (PRISMAP), University of Florida, Gainesville, FL, United States","institution_ids":["https://openalex.org/I33213144","https://openalex.org/I4210104680"]},{"raw_affiliation_string":"Department of Computer and Information Science and Engineering, University of Florida, Gainesville, FL, United States","institution_ids":["https://openalex.org/I33213144"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058579794","display_name":"Anis Davoudi","orcid":"https://orcid.org/0000-0002-3383-9481"},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"funder","lineage":["https://openalex.org/I33213144"]},{"id":"https://openalex.org/I4210104680","display_name":"Proteogenomics Research Institute for Systems Medicine","ror":"https://ror.org/01c44a921","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210104680"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anis Davoudi","raw_affiliation_strings":["Department of Biomedical Engineering, University of Florida, Gainesville, FL, United States","Precision and Intelligent Systems in Medicine (PRISMAP), University of Florida, Gainesville, FL, United States"],"affiliations":[{"raw_affiliation_string":"Precision and Intelligent Systems in Medicine (PRISMAP), University of Florida, Gainesville, FL, United States","institution_ids":["https://openalex.org/I33213144","https://openalex.org/I4210104680"]},{"raw_affiliation_string":"Department of Biomedical Engineering, University of Florida, Gainesville, FL, United States","institution_ids":["https://openalex.org/I33213144"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003769975","display_name":"Tezcan Ozrazgat\u2010Baslanti","orcid":"https://orcid.org/0000-0002-1158-9928"},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"funder","lineage":["https://openalex.org/I33213144"]},{"id":"https://openalex.org/I4210104680","display_name":"Proteogenomics Research Institute for Systems Medicine","ror":"https://ror.org/01c44a921","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210104680"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tezcan Ozrazgat-Baslanti","raw_affiliation_strings":["Department of Medicine, University of Florida, Gainesville, FL, United States","Precision and Intelligent Systems in Medicine (PRISMAP), University of Florida, Gainesville, FL, United States"],"affiliations":[{"raw_affiliation_string":"Precision and Intelligent Systems in Medicine (PRISMAP), University of Florida, Gainesville, FL, United States","institution_ids":["https://openalex.org/I33213144","https://openalex.org/I4210104680"]},{"raw_affiliation_string":"Department of Medicine, University of Florida, Gainesville, FL, United States","institution_ids":["https://openalex.org/I33213144"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053410431","display_name":"Matthew M. Ruppert","orcid":"https://orcid.org/0000-0001-9757-4454"},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"funder","lineage":["https://openalex.org/I33213144"]},{"id":"https://openalex.org/I4210104680","display_name":"Proteogenomics Research Institute for Systems Medicine","ror":"https://ror.org/01c44a921","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210104680"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthew Ruppert","raw_affiliation_strings":["Department of Medicine, University of Florida, Gainesville, FL, United States","Precision and Intelligent Systems in Medicine (PRISMAP), University of Florida, Gainesville, FL, United States"],"affiliations":[{"raw_affiliation_string":"Precision and Intelligent Systems in Medicine (PRISMAP), University of Florida, Gainesville, FL, United States","institution_ids":["https://openalex.org/I33213144","https://openalex.org/I4210104680"]},{"raw_affiliation_string":"Department of Medicine, University of Florida, Gainesville, FL, United States","institution_ids":["https://openalex.org/I33213144"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016909804","display_name":"Azra Bihorac","orcid":"https://orcid.org/0000-0002-5745-2863"},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"funder","lineage":["https://openalex.org/I33213144"]},{"id":"https://openalex.org/I4210104680","display_name":"Proteogenomics Research Institute for Systems Medicine","ror":"https://ror.org/01c44a921","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210104680"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Azra Bihorac","raw_affiliation_strings":["Department of Medicine, University of Florida, Gainesville, FL, United States","Precision and Intelligent Systems in Medicine (PRISMAP), University of Florida, Gainesville, FL, United States"],"affiliations":[{"raw_affiliation_string":"Precision and Intelligent Systems in Medicine (PRISMAP), University of Florida, Gainesville, FL, United States","institution_ids":["https://openalex.org/I33213144","https://openalex.org/I4210104680"]},{"raw_affiliation_string":"Department of Medicine, University of Florida, Gainesville, FL, United States","institution_ids":["https://openalex.org/I33213144"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007040136","display_name":"Parisa Rashidi","orcid":"https://orcid.org/0000-0003-4530-2048"},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"funder","lineage":["https://openalex.org/I33213144"]},{"id":"https://openalex.org/I4210104680","display_name":"Proteogenomics Research Institute for Systems Medicine","ror":"https://ror.org/01c44a921","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210104680"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Parisa Rashidi","raw_affiliation_strings":["Department of Biomedical Engineering, University of Florida, Gainesville, FL, United States","Department of Computer and Information Science and Engineering, University of Florida, Gainesville, FL, United States","Precision and Intelligent Systems in Medicine (PRISMAP), University of Florida, Gainesville, FL, United States"],"affiliations":[{"raw_affiliation_string":"Precision and Intelligent Systems in Medicine (PRISMAP), University of Florida, Gainesville, FL, United States","institution_ids":["https://openalex.org/I33213144","https://openalex.org/I4210104680"]},{"raw_affiliation_string":"Department of Computer and Information Science and Engineering, University of Florida, Gainesville, FL, United States","institution_ids":["https://openalex.org/I33213144"]},{"raw_affiliation_string":"Department of Biomedical Engineering, University of Florida, Gainesville, FL, United States","institution_ids":["https://openalex.org/I33213144"]}]}],"institution_assertions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5007040136"],"corresponding_institution_ids":["https://openalex.org/I33213144","https://openalex.org/I4210104680"],"apc_list":{"value":1900,"currency":"USD","value_usd":1900},"apc_paid":{"value":1900,"currency":"USD","value_usd":1900},"fwci":1.662,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.999974,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":92},"biblio":{"volume":"3","issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"primary_topic":{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.9994,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.9994,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":0.9941,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10867","display_name":"Intensive Care Unit Cognitive Disorders","score":0.9813,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/transfer-of-learning","display_name":"Transfer of learning","score":0.66823107},{"id":"https://openalex.org/keywords/health-records","display_name":"Health records","score":0.41782767}],"concepts":[{"id":"https://openalex.org/C150899416","wikidata":"https://www.wikidata.org/wiki/Q1820378","display_name":"Transfer of learning","level":2,"score":0.66823107},{"id":"https://openalex.org/C2776376669","wikidata":"https://www.wikidata.org/wiki/Q5094647","display_name":"Intensive care unit","level":2,"score":0.584705},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5560401},{"id":"https://openalex.org/C150594956","wikidata":"https://www.wikidata.org/wiki/Q1334829","display_name":"Wearable computer","level":2,"score":0.50507003},{"id":"https://openalex.org/C2987404301","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care","level":2,"score":0.4874885},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.4810079},{"id":"https://openalex.org/C160735492","wikidata":"https://www.wikidata.org/wiki/Q31207","display_name":"Health care","level":2,"score":0.4596114},{"id":"https://openalex.org/C3019952477","wikidata":"https://www.wikidata.org/wiki/Q1324077","display_name":"Health records","level":3,"score":0.41782767},{"id":"https://openalex.org/C545542383","wikidata":"https://www.wikidata.org/wiki/Q2751242","display_name":"Medical emergency","level":1,"score":0.41244328},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.41101322},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.39471877},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.37831262},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.34541357},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.29639506},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C149635348","wikidata":"https://www.wikidata.org/wiki/Q193040","display_name":"Embedded system","level":1,"score":0.0},{"id":"https://openalex.org/C50522688","wikidata":"https://www.wikidata.org/wiki/Q189833","display_name":"Economic growth","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"is_oa":true,"landing_page_url":"https://doi.org/10.3389/fdgth.2021.640685","pdf_url":"https://www.frontiersin.org/articles/10.3389/fdgth.2021.640685/pdf","source":{"id":"https://openalex.org/S4210170686","display_name":"Frontiers in Digital Health","issn_l":"2673-253X","issn":["2673-253X"],"is_oa":true,"is_in_doaj":true,"is_indexed_in_scopus":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true},{"is_oa":false,"landing_page_url":"https://doaj.org/article/70696cc117fa4ad68c6a94048df4f0fe","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_indexed_in_scopus":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false},{"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954405","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_indexed_in_scopus":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":["National Institutes of Health"],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true},{"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33718920","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_indexed_in_scopus":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":["National Institutes of Health"],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false}],"best_oa_location":{"is_oa":true,"landing_page_url":"https://doi.org/10.3389/fdgth.2021.640685","pdf_url":"https://www.frontiersin.org/articles/10.3389/fdgth.2021.640685/pdf","source":{"id":"https://openalex.org/S4210170686","display_name":"Frontiers in Digital Health","issn_l":"2673-253X","issn":["2673-253X"],"is_oa":true,"is_in_doaj":true,"is_indexed_in_scopus":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true},"sustainable_development_goals":[{"score":0.45,"id":"https://metadata.un.org/sdg/8","display_name":"Decent work and economic growth"}],"grants":[{"funder":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences","award_id":null},{"funder":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","award_id":null},{"funder":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering","award_id":null}],"datasets":[],"versions":[],"referenced_works_count":29,"referenced_works":["https://openalex.org/W1526529787","https://openalex.org/W1898928487","https://openalex.org/W1929228473","https://openalex.org/W1987245061","https://openalex.org/W2000566182","https://openalex.org/W2014224402","https://openalex.org/W2028137374","https://openalex.org/W2042283868","https://openalex.org/W2046451218","https://openalex.org/W2060798143","https://openalex.org/W2069176051","https://openalex.org/W2072492033","https://openalex.org/W2087694898","https://openalex.org/W2099442042","https://openalex.org/W2110317531","https://openalex.org/W2111824593","https://openalex.org/W2130235768","https://openalex.org/W2141220041","https://openalex.org/W2158212162","https://openalex.org/W2306989133","https://openalex.org/W2518582440","https://openalex.org/W2625625371","https://openalex.org/W2889037799","https://openalex.org/W2937636883","https://openalex.org/W2947961778","https://openalex.org/W2968723626","https://openalex.org/W3098949126","https://openalex.org/W3099382201","https://openalex.org/W3104523752"],"related_works":["https://openalex.org/W3036062714","https://openalex.org/W2740671600","https://openalex.org/W2474790959","https://openalex.org/W2362037864","https://openalex.org/W2331454882","https://openalex.org/W2280614645","https://openalex.org/W2274076556","https://openalex.org/W2057630253","https://openalex.org/W2000329364","https://openalex.org/W1984498786"],"abstract_inverted_index":{"Accurate":[0],"prediction":[1,34],"and":[2,23,99],"monitoring":[3],"of":[4,18,53,67,87,136,157,166,186],"patient":[5,32,88,171],"health":[6,42,97],"in":[7,140],"the":[8,51,73,119,130,134],"intensive":[9,24,120],"care":[10,19,25,121],"unit":[11,122],"can":[12],"inform":[13],"shared":[14],"decisions":[15],"regarding":[16],"appropriateness":[17],"delivery,":[20],"risk-reduction":[21],"strategies,":[22],"resource":[26],"use.":[27],"Traditionally,":[28],"algorithmic":[29],"solutions":[30],"for":[31,110,169],"outcome":[33],"rely":[35],"solely":[36],"on":[37,83],"data":[38,57,102,151],"available":[39],"from":[40,61,95,104,129,152],"electronic":[41,96],"records":[43],"(EHR).":[44],"In":[45],"this":[46],"pilot":[47],"study,":[48],"we":[49],"explore":[50],"benefits":[52],"augmenting":[54],"existing":[55],"EHR":[56,150],"with":[58],"novel":[59,182],"measurements":[60,168],"wrist-worn":[62],"activity":[63,101],"sensors":[64],"as":[65,72],"part":[66],"a":[68,108,153,176],"clinical":[69],"environment":[70],"known":[71],"Intelligent":[74,183],"ICU.":[75],"We":[76,132],"implemented":[77],"temporal":[78],"deep":[79,146],"learning":[80,148,178],"models":[81,114],"based":[82],"two":[84],"distinct":[85],"sources":[86],"data:":[89],"(1)":[90],"routinely":[91],"measured":[92],"vital":[93],"signs":[94],"records,":[98],"(2)":[100],"collected":[103],"wearable":[105],"sensors.":[106],"As":[107],"proxy":[109],"illness":[111],"severity,":[112],"our":[113,141],"predicted":[115],"whether":[116],"patients":[117],"leaving":[118],"would":[123],"be":[124],"successfully":[125],"or":[126],"unsuccessfully":[127],"discharged":[128],"hospital.":[131],"overcome":[133],"challenge":[135],"small":[137,181],"sample":[138],"size":[139],"prospective":[142],"cohort":[143,156],"by":[144],"applying":[145,175],"transfer":[147,177],"using":[149],"much":[154],"larger":[155],"traditional":[158],"ICU":[159,184],"patients.":[160,189],"Our":[161],"experiments":[162],"quantify":[163],"added":[164],"utility":[165],"non-traditional":[167],"predicting":[170],"health,":[172],"especially":[173],"when":[174],"procedure":[179],"to":[180],"cohorts":[185],"critically":[187],"ill":[188]},"abstract_inverted_index_v3":null,"cited_by_api_url":"https://api.openalex.org/works?filter=cites:W3131846890","counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":3}],"updated_date":"2025-04-30T16:11:51.693303","created_date":"2021-03-01"}