{"id":"https://openalex.org/W2201294065","doi":"https://doi.org/10.1186/1472-6947-15-s5-s3","title":"Private genome analysis through homomorphic encryption","display_name":"Private genome analysis through homomorphic encryption","publication_year":2015,"publication_date":"2015-12-01","ids":{"openalex":"https://openalex.org/W2201294065","doi":"https://doi.org/10.1186/1472-6947-15-s5-s3","mag":"2201294065","pmid":"https://pubmed.ncbi.nlm.nih.gov/26733152","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4699052"},"language":"en","primary_location":{"is_oa":true,"landing_page_url":"https://doi.org/10.1186/1472-6947-15-s5-s3","pdf_url":"https://bmcmedinformdecismak.biomedcentral.com/track/pdf/10.1186/1472-6947-15-S5-S3","source":{"id":"https://openalex.org/S107516304","display_name":"BMC Medical Informatics and Decision Making","issn_l":"1472-6947","issn":["1472-6947"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310319965","https://openalex.org/P4310320256"],"host_organization_lineage_names":["Springer Nature","BioMed Central"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true},"type":"article","type_crossref":"journal-article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcmedinformdecismak.biomedcentral.com/track/pdf/10.1186/1472-6947-15-S5-S3","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091504641","display_name":"Miran Kim","orcid":"https://orcid.org/0000-0003-3564-6090"},"institutions":[{"id":"https://openalex.org/I4210158432","display_name":"National Institute for Mathematical Sciences","ror":"https://ror.org/04n7py080","country_code":"KR","type":"education","lineage":["https://openalex.org/I4210158432"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Miran Kim","raw_affiliation_strings":["Department of Mathematical Sciences, Seoul, Korea"],"affiliations":[{"raw_affiliation_string":"Department of Mathematical Sciences, Seoul, Korea","institution_ids":["https://openalex.org/I4210158432"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002850656","display_name":"Kristin Lauter","orcid":"https://orcid.org/0000-0002-1320-696X"},"institutions":[{"id":"https://openalex.org/I1290206253","display_name":"Microsoft (United States)","ror":"https://ror.org/00d0nc645","country_code":"US","type":"company","lineage":["https://openalex.org/I1290206253"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kristin Lauter","raw_affiliation_strings":["Cryptography Research Group, Microsoft Research, Redmond, USA"],"affiliations":[{"raw_affiliation_string":"Cryptography Research Group, Microsoft Research, Redmond, USA","institution_ids":["https://openalex.org/I1290206253"]}]}],"institution_assertions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5091504641"],"corresponding_institution_ids":["https://openalex.org/I4210158432"],"apc_list":{"value":1570,"currency":"GBP","value_usd":1925,"provenance":"doaj"},"apc_paid":{"value":1570,"currency":"GBP","value_usd":1925,"provenance":"doaj"},"fwci":11.475,"has_fulltext":true,"fulltext_origin":"ngrams","cited_by_count":114,"citation_normalized_percentile":{"value":0.953758,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":"15","issue":"S5","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"primary_topic":{"id":"https://openalex.org/T10237","display_name":"Cryptography and Data Security","score":0.9997,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10237","display_name":"Cryptography and Data Security","score":0.9997,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10764","display_name":"Privacy-Preserving Technologies in Data","score":0.9983,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13768","display_name":"Oral and gingival health research","score":0.9826,"subfield":{"id":"https://openalex.org/subfields/3611","display_name":"Pharmacy"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/homomorphic-encryption","display_name":"Homomorphic Encryption","score":0.85563123},{"id":"https://openalex.org/keywords/edit-distance","display_name":"Edit distance","score":0.6826161},{"id":"https://openalex.org/keywords/hamming-distance","display_name":"Hamming distance","score":0.47999734}],"concepts":[{"id":"https://openalex.org/C158338273","wikidata":"https://www.wikidata.org/wiki/Q2154943","display_name":"Homomorphic encryption","level":3,"score":0.85563123},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7312674},{"id":"https://openalex.org/C44359876","wikidata":"https://www.wikidata.org/wiki/Q5338467","display_name":"Edit distance","level":2,"score":0.6826161},{"id":"https://openalex.org/C148730421","wikidata":"https://www.wikidata.org/wiki/Q141090","display_name":"Encryption","level":2,"score":0.6070509},{"id":"https://openalex.org/C193319292","wikidata":"https://www.wikidata.org/wiki/Q272172","display_name":"Hamming distance","level":2,"score":0.47999734},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.44793427},{"id":"https://openalex.org/C178489894","wikidata":"https://www.wikidata.org/wiki/Q8789","display_name":"Cryptography","level":2,"score":0.421553},{"id":"https://openalex.org/C77618280","wikidata":"https://www.wikidata.org/wiki/Q1155772","display_name":"Scheme (mathematics)","level":2,"score":0.41674125},{"id":"https://openalex.org/C79974875","wikidata":"https://www.wikidata.org/wiki/Q483639","display_name":"Cloud computing","level":2,"score":0.41198182},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.3007047},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.16807073},{"id":"https://openalex.org/C31258907","wikidata":"https://www.wikidata.org/wiki/Q1301371","display_name":"Computer network","level":1,"score":0.15638047},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000067917","descriptor_name":"Cloud Computing","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005787","descriptor_name":"Gene Frequency","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":"","qualifier_name":null,"is_major_topic":false}],"locations_count":8,"locations":[{"is_oa":true,"landing_page_url":"https://doi.org/10.1186/1472-6947-15-s5-s3","pdf_url":"https://bmcmedinformdecismak.biomedcentral.com/track/pdf/10.1186/1472-6947-15-S5-S3","source":{"id":"https://openalex.org/S107516304","display_name":"BMC Medical Informatics and Decision Making","issn_l":"1472-6947","issn":["1472-6947"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310319965","https://openalex.org/P4310320256"],"host_organization_lineage_names":["Springer Nature","BioMed Central"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true},{"is_oa":true,"landing_page_url":"https://europepmc.org/articles/pmc4699052","pdf_url":"https://europepmc.org/articles/pmc4699052?pdf=render","source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":["European Bioinformatics Institute"],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true},{"is_oa":true,"landing_page_url":"https://bmcmedinformdecismak.biomedcentral.com/articles/10.1186/1472-6947-15-S5-S3","pdf_url":"https://bmcmedinformdecismak.biomedcentral.com/counter/pdf/10.1186/1472-6947-15-S5-S3","source":{"id":"https://openalex.org/S4306401118","display_name":"Scholarworks@UNIST (Ulsan National Institute of Science and Technology)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I48566637","host_organization_name":"Ulsan National Institute of Science and Technology","host_organization_lineage":["https://openalex.org/I48566637"],"host_organization_lineage_names":["Ulsan National Institute of Science and Technology"],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true},{"is_oa":true,"landing_page_url":"http://hdl.handle.net/10371/100591","pdf_url":"https://s-space.snu.ac.kr/bitstream/10371/100591/1/12911_2015_Article_927.pdf","source":{"id":"https://openalex.org/S4306401345","display_name":"Seoul National University Open Repository (Seoul National University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I139264467","host_organization_name":"Seoul National University","host_organization_lineage":["https://openalex.org/I139264467"],"host_organization_lineage_names":["Seoul National University"],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true},{"is_oa":true,"landing_page_url":"https://scholarworks.unist.ac.kr/handle/201301/48115","pdf_url":"https://scholarworks.unist.ac.kr/bitstream/201301/48115/1/Private%20genome%20analysis%20through%20homomorphic%20encryption.pdf","source":{"id":"https://openalex.org/S4306401118","display_name":"Scholarworks@UNIST (Ulsan National Institute of Science and Technology)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I48566637","host_organization_name":"Ulsan National Institute of Science and Technology","host_organization_lineage":["https://openalex.org/I48566637"],"host_organization_lineage_names":["Ulsan National Institute of Science and Technology"],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true},{"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699052","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":["National Institutes of Health"],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true},{"is_oa":true,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.738.1876","pdf_url":"http://eprint.iacr.org/2015/965.pdf","source":{"id":"https://openalex.org/S4306400349","display_name":"CiteSeer X (The Pennsylvania State University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I130769515","host_organization_name":"Pennsylvania State University","host_organization_lineage":["https://openalex.org/I130769515"],"host_organization_lineage_names":["Pennsylvania State University"],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false},{"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26733152","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":["National Institutes of Health"],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false}],"best_oa_location":{"is_oa":true,"landing_page_url":"https://doi.org/10.1186/1472-6947-15-s5-s3","pdf_url":"https://bmcmedinformdecismak.biomedcentral.com/track/pdf/10.1186/1472-6947-15-S5-S3","source":{"id":"https://openalex.org/S107516304","display_name":"BMC Medical Informatics and Decision Making","issn_l":"1472-6947","issn":["1472-6947"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310319965","https://openalex.org/P4310320256"],"host_organization_lineage_names":["Springer Nature","BioMed Central"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true},"sustainable_development_goals":[{"score":0.44,"display_name":"Partnerships for the goals","id":"https://metadata.un.org/sdg/17"}],"grants":[],"datasets":[],"versions":[],"referenced_works_count":31,"referenced_works":["https://openalex.org/W1019809662","https://openalex.org/W133884053","https://openalex.org/W1583235570","https://openalex.org/W1936753088","https://openalex.org/W1966731635","https://openalex.org/W1970026646","https://openalex.org/W1980132682","https://openalex.org/W1987521207","https://openalex.org/W2002458933","https://openalex.org/W2022028092","https://openalex.org/W2031533839","https://openalex.org/W2031855568","https://openalex.org/W2048994663","https://openalex.org/W2060238632","https://openalex.org/W2077905990","https://openalex.org/W2087135382","https://openalex.org/W2098290658","https://openalex.org/W2106970188","https://openalex.org/W2124398102","https://openalex.org/W2152926062","https://openalex.org/W2156030242","https://openalex.org/W2164327070","https://openalex.org/W2226167778","https://openalex.org/W2233194383","https://openalex.org/W2284068942","https://openalex.org/W2285574614","https://openalex.org/W2401959250","https://openalex.org/W2913761579","https://openalex.org/W4297927038","https://openalex.org/W56544557","https://openalex.org/W87154849"],"related_works":["https://openalex.org/W2888987343","https://openalex.org/W2887779253","https://openalex.org/W2612888708","https://openalex.org/W2611868502","https://openalex.org/W2416529140","https://openalex.org/W2180288160","https://openalex.org/W2165259681","https://openalex.org/W162676011","https://openalex.org/W1531307672","https://openalex.org/W1494289317"],"abstract_inverted_index":{"The":[0,28,147,204],"rapid":[1],"development":[2],"of":[3,30,74,84,121,194],"genome":[4,12,75],"sequencing":[5],"technology":[6],"allows":[7],"researchers":[8],"to":[9,34,102,184,236],"access":[10],"large":[11],"datasets.":[13],"However,":[14],"outsourcing":[15],"the":[16,20,49,60,67,72,85,105,129,138,150,176,187,200,219,229,238],"data":[17,68,154],"processing":[18],"o":[19],"cloud":[21,57],"poses":[22],"high":[23],"risks":[24],"for":[25,39,81,191,207,241],"personal":[26],"privacy.":[27],"aim":[29],"this":[31,40],"paper":[32],"is":[33,233],"give":[35],"a":[36,93,164,242,255],"practical":[37,124],"solution":[38],"problem":[41],"using":[42,122,175],"homomorphic":[43,125],"encryption.":[44],"In":[45],"our":[46],"approach,":[47],"all":[48],"computations":[50],"can":[51],"be":[52],"performed":[53],"in":[54,92,254],"an":[55],"untrusted":[56],"without":[58],"requiring":[59],"decryption":[61],"key":[62],"or":[63,223,250],"any":[64],"interaction":[65],"with":[66,149,167],"owner,":[69],"which":[70],"preserves":[71],"privacy":[73],"data.":[76],"We":[77,98],"present":[78],"evaluation":[79],"algorithms":[80],"secure":[82],"computation":[83],"minor":[86,247],"allele":[87,248],"frequencies":[88,249],"and":[89,108,135,137,145,162,197],"\u03c72":[90,251],"statistic":[91,253],"genome-wide":[94],"association":[95],"studies":[96],"setting.":[97],"also":[99],"describe":[100],"how":[101],"privately":[103],"compute":[104,186],"Hamming":[106,220],"distance":[107,111,190,221,226],"approximate":[109,188,224],"Edit":[110,189,225],"between":[112,202],"encrypted":[113],"DNA":[114,192],"sequences.":[115],"Finally,":[116],"we":[117],"compare":[118],"performance":[119,205],"details":[120],"two":[123],"encryption":[126],"schemes":[127],"-":[128],"BGV":[130,177,208],"scheme":[131,140,152,240],"by":[132,141],"Gentry,":[133],"Halevi":[134],"Smart":[136],"YASHE":[139,151,212,239],"Bos,":[142],"Lauter,":[143],"Loftus":[144],"Naehrig.":[146],"approach":[148],"analyzes":[153],"from":[155,169],"400":[156],"people":[157],"within":[158],"about":[159,181],"2":[160],"seconds":[161,183],"picks":[163],"variant":[165],"associated":[166],"disease":[168],"311":[170],"spots.":[171],"For":[172],"another":[173],"task,":[174],"scheme,":[178],"it":[179,232],"took":[180],"65":[182],"securely":[185],"sequences":[193],"size":[195],"5K":[196],"figure":[198],"out":[199],"differences":[201],"them.":[203],"numbers":[206],"are":[209],"better":[210],"than":[211],"when":[213],"homomorphically":[214],"evaluating":[215],"deep":[216],"circuits":[217],"(like":[218],"algorithm":[222],"algorithm).":[227],"On":[228],"other":[230],"hand,":[231],"more":[234],"efficient":[235],"use":[237],"low-degree":[243],"computation,":[244],"such":[245],"as":[246],"test":[252],"case-control":[256],"study.":[257]},"cited_by_api_url":"https://api.openalex.org/works?filter=cites:W2201294065","counts_by_year":[{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":13},{"year":2022,"cited_by_count":18},{"year":2021,"cited_by_count":16},{"year":2020,"cited_by_count":10},{"year":2019,"cited_by_count":10},{"year":2018,"cited_by_count":15},{"year":2017,"cited_by_count":16},{"year":2016,"cited_by_count":8}],"updated_date":"2024-12-30T01:39:13.870059","created_date":"2016-06-24"}