{"id":"https://openalex.org/W2057966302","doi":"https://doi.org/10.1145/332306.332326","title":"Human and mouse gene structure","display_name":"Human and mouse gene structure","publication_year":2000,"publication_date":"2000-04-08","ids":{"openalex":"https://openalex.org/W2057966302","doi":"https://doi.org/10.1145/332306.332326","mag":"2057966302"},"language":"en","primary_location":{"is_oa":false,"landing_page_url":"https://doi.org/10.1145/332306.332326","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false},"type":"article","type_crossref":"proceedings-article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108224144","display_name":"Serafim Batzoglou","orcid":null},"institutions":[{"id":"https://openalex.org/I4210157710","display_name":"Whitehead Institute for Biomedical Research","ror":"https://ror.org/04vqm6w82","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210157710","https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Serafim Batzoglou","raw_affiliation_strings":["Laboratory for Computer Science, MIT, Cambridge, MA and Whitehead Institute for Biomedical Research, Nine Cambridge Center, Cambridge, MA"],"affiliations":[{"raw_affiliation_string":"Laboratory for Computer Science, MIT, Cambridge, MA and Whitehead Institute for Biomedical Research, Nine Cambridge Center, Cambridge, MA","institution_ids":["https://openalex.org/I4210157710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020008219","display_name":"Lior Pachter","orcid":"https://orcid.org/0000-0002-9164-6231"},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lior Pachter","raw_affiliation_strings":["Department of Mathematics, UC Berkeley, Berkeley, CA#TAB#"],"affiliations":[{"raw_affiliation_string":"Department of Mathematics, UC Berkeley, Berkeley, CA#TAB#","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077622597","display_name":"Jill P. Mesirov","orcid":"https://orcid.org/0000-0002-9755-2818"},"institutions":[{"id":"https://openalex.org/I4210157710","display_name":"Whitehead Institute for Biomedical Research","ror":"https://ror.org/04vqm6w82","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210157710","https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jill Mesirov","raw_affiliation_strings":["Whitehead Institute for Biomedical Research Nine Cambridge Center, Cambridge, MA."],"affiliations":[{"raw_affiliation_string":"Whitehead Institute for Biomedical Research Nine Cambridge Center, Cambridge, MA.","institution_ids":["https://openalex.org/I4210157710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044078921","display_name":"Bonnie Berger","orcid":"https://orcid.org/0000-0002-2724-7228"},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bonnie Berger","raw_affiliation_strings":["Department of Mathematics, MIT Cambridge, MA and ESL and Laboratory for Computer Science, MIT, Cambridge, MA#TAB#"],"affiliations":[{"raw_affiliation_string":"Department of Mathematics, MIT Cambridge, MA and ESL and Laboratory for Computer Science, MIT, Cambridge, MA#TAB#","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5020748592","display_name":"Eric S. Lander","orcid":"https://orcid.org/0000-0003-2662-4631"},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric S. Lander","raw_affiliation_strings":["Department of Biology, MIT, Cambridge, MA and ESL and Whitehead Institute for Biomedical Research, Nine Cambridge Center, Cambridge, MA#TAB#"],"affiliations":[{"raw_affiliation_string":"Department of Biology, MIT, Cambridge, MA and ESL and Whitehead Institute for Biomedical Research, Nine Cambridge Center, Cambridge, MA#TAB#","institution_ids":["https://openalex.org/I63966007"]}]}],"institution_assertions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.161,"has_fulltext":true,"fulltext_origin":"ngrams","cited_by_count":14,"citation_normalized_percentile":{"value":0.787879,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":82,"max":83},"biblio":{"volume":"90","issue":null,"first_page":"46","last_page":"53"},"is_retracted":false,"is_paratext":false,"primary_topic":{"id":"https://openalex.org/T12946","display_name":"Fractal and DNA sequence analysis","score":0.9992,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12946","display_name":"Fractal and DNA sequence analysis","score":0.9992,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9988,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9986,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/orthologous-gene","display_name":"Orthologous Gene","score":0.53300416},{"id":"https://openalex.org/keywords/coding-region","display_name":"Coding region","score":0.52742755},{"id":"https://openalex.org/keywords/gene-prediction","display_name":"Gene prediction","score":0.47421885},{"id":"https://openalex.org/keywords/sequence","display_name":"Sequence (biology)","score":0.4609424},{"id":"https://openalex.org/keywords/identification","display_name":"Identification","score":0.4468261}],"concepts":[{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.7264542},{"id":"https://openalex.org/C36823959","wikidata":"https://www.wikidata.org/wiki/Q373027","display_name":"Exon","level":3,"score":0.6599747},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6206764},{"id":"https://openalex.org/C94671646","wikidata":"https://www.wikidata.org/wiki/Q207551","display_name":"Intron","level":3,"score":0.59033805},{"id":"https://openalex.org/C197077220","wikidata":"https://www.wikidata.org/wiki/Q720988","display_name":"Human genome","level":4,"score":0.5447555},{"id":"https://openalex.org/C2909108991","wikidata":"https://www.wikidata.org/wiki/Q414601","display_name":"Orthologous Gene","level":4,"score":0.53300416},{"id":"https://openalex.org/C91779695","wikidata":"https://www.wikidata.org/wiki/Q3780824","display_name":"Coding region","level":3,"score":0.52742755},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.51562136},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.48163477},{"id":"https://openalex.org/C105565629","wikidata":"https://www.wikidata.org/wiki/Q1248292","display_name":"Gene prediction","level":4,"score":0.47421885},{"id":"https://openalex.org/C2778112365","wikidata":"https://www.wikidata.org/wiki/Q3511065","display_name":"Sequence (biology)","level":2,"score":0.4609424},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.4468261},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4387711},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.35307762},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.34862372},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"is_oa":false,"landing_page_url":"https://doi.org/10.1145/332306.332326","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Life on land","score":0.7,"id":"https://metadata.un.org/sdg/15"}],"grants":[],"datasets":[],"versions":[],"referenced_works_count":31,"referenced_works":["https://openalex.org/W1509651969","https://openalex.org/W1545361216","https://openalex.org/W1584796599","https://openalex.org/W1821582542","https://openalex.org/W1826006981","https://openalex.org/W1832870753","https://openalex.org/W1963502101","https://openalex.org/W1966833356","https://openalex.org/W1985182478","https://openalex.org/W1999510229","https://openalex.org/W2003130517","https://openalex.org/W2008431627","https://openalex.org/W2010838245","https://openalex.org/W2010991089","https://openalex.org/W2014339335","https://openalex.org/W2044240840","https://openalex.org/W2055525504","https://openalex.org/W2057801650","https://openalex.org/W2062222238","https://openalex.org/W2074231493","https://openalex.org/W2074728296","https://openalex.org/W2079501979","https://openalex.org/W2087064593","https://openalex.org/W2133138033","https://openalex.org/W2135677342","https://openalex.org/W2149238618","https://openalex.org/W2160053034","https://openalex.org/W2166187656","https://openalex.org/W2169898794","https://openalex.org/W2471626689","https://openalex.org/W2611200729"],"related_works":["https://openalex.org/W4250059184","https://openalex.org/W3034200848","https://openalex.org/W2480459968","https://openalex.org/W2141847640","https://openalex.org/W2029750512","https://openalex.org/W1985744573","https://openalex.org/W1973164572","https://openalex.org/W1601262025","https://openalex.org/W1549276859","https://openalex.org/W1510144579"],"abstract_inverted_index":{"We":[0,13,41],"describe":[1],"a":[2,16],"novel":[3],"analytical":[4],"approach":[5,45],"to":[6],"gene":[7,83],"recognition":[8,84],"based":[9,68],"on":[10,69],"cross-species":[11],"comparison":[12,17],"first":[14,54],"undertook":[15],"of":[18,29,37,71,101],"orthologous":[19,51,106],"genomic":[20],"look":[21],"from":[22],"human":[23],"and":[24,35,39,64,82,92],"mouse,":[25],"studying":[26],"the":[27,32,56],"extent":[28],"similarity":[30],"in":[31,77,104],"number,":[33],"size":[34],"sequence":[36],"exons":[38,103],"introns":[40],"then":[42,65],"developed":[43],"an":[44,59],"for":[46],"recognizing":[47],"genes":[48,67],"within":[49],"such":[50],"regions,":[52],"by":[53,87],"aligning":[55],"regions":[57],"using":[58],"iterative":[60],"global":[61],"alignment":[62,81],"system":[63],"identifying":[66],"conservation":[70],"exonic":[72],"features":[73],"at":[74,98],"aligned":[75],"positions":[76],"both":[78],"species":[79],"The":[80],"are":[85],"performed":[86,96],"new":[88],"programs":[89],"called":[90],"GLASS":[91],"ROSETTA,":[93],"respectively":[94],"ROSETTA":[95],"well":[97],"exact":[99],"identification":[100],"coding":[102],"117":[105],"pairs":[107],"tested.":[108]},"cited_by_api_url":"https://api.openalex.org/works?filter=cites:W2057966302","counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2024-12-11T12:00:29.522607","created_date":"2016-06-24"}