乐胖代购免代理版

{"id":"https://openalex.org/W2072473279","doi":"https://doi.org/10.1142/s0129065711002894","title":"RESPONSIVE NEUROMODULATORS BASED ON ARTIFICIAL NEURAL NETWORKS USED TO CONTROL SEIZURE-LIKE EVENTS IN A COMPUTATIONAL MODEL OF EPILEPSY","display_name":"RESPONSIVE NEUROMODULATORS BASED ON ARTIFICIAL NEURAL NETWORKS USED TO CONTROL SEIZURE-LIKE EVENTS IN A COMPUTATIONAL MODEL OF EPILEPSY","publication_year":2011,"publication_date":"2011-09-26","ids":{"openalex":"https://openalex.org/W2072473279","doi":"https://doi.org/10.1142/s0129065711002894","mag":"2072473279","pmid":"https://pubmed.ncbi.nlm.nih.gov/21956930"},"language":"en","primary_location":{"is_oa":false,"landing_page_url":"https://doi.org/10.1142/s0129065711002894","pdf_url":null,"source":{"id":"https://openalex.org/S197665576","display_name":"International Journal of Neural Systems","issn_l":"0129-0657","issn":["0129-0657","1793-6462"],"is_oa":false,"is_in_doaj":false,"is_indexed_in_scopus":true,"is_core":true,"host_organization":"https://openalex.org/P4310319815","host_organization_name":"World Scientific","host_organization_lineage":["https://openalex.org/P4310319815"],"host_organization_lineage_names":["World Scientific"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false},"type":"article","type_crossref":"journal-article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037647409","display_name":"Sinisa Colic","orcid":null},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"funder","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"SINISA COLIC","raw_affiliation_strings":["Edwards S. Rogers Sr. Department of Electrical and Computer Engineering, University of Toronto, Toronto, ON, M5S 3G4, Canada"],"affiliations":[{"raw_affiliation_string":"Edwards S. Rogers Sr. Department of Electrical and Computer Engineering, University of Toronto, Toronto, ON, M5S 3G4, Canada","institution_ids":["https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065791992","display_name":"Osbert C. Zalay","orcid":"https://orcid.org/0000-0002-2967-4071"},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"funder","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"OSBERT C. ZALAY","raw_affiliation_strings":["Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON, M5S 3G9, Canada"],"affiliations":[{"raw_affiliation_string":"Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON, M5S 3G9, Canada","institution_ids":["https://openalex.org/I185261750"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000047757","display_name":"Berj L. Bardakjian","orcid":"https://orcid.org/0000-0001-9969-4775"},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"funder","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"BERJ L. BARDAKJIAN","raw_affiliation_strings":["Edwards S. Rogers Sr. Department of Electrical and Computer Engineering, University of Toronto, Toronto, ON, M5S 3G4, Canada","Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON, M5S 3G9, Canada"],"affiliations":[{"raw_affiliation_string":"Edwards S. Rogers Sr. Department of Electrical and Computer Engineering, University of Toronto, Toronto, ON, M5S 3G4, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON, M5S 3G9, Canada","institution_ids":["https://openalex.org/I185261750"]}]}],"institution_assertions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.096,"has_fulltext":true,"fulltext_origin":"ngrams","cited_by_count":24,"citation_normalized_percentile":{"value":0.658868,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":91},"biblio":{"volume":"21","issue":"05","first_page":"367","last_page":"383"},"is_retracted":false,"is_paratext":false,"primary_topic":{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.9998,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.9998,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.9997,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10919","display_name":"Neurological disorders and treatments","score":0.9996,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neuromodulation","display_name":"Neuromodulation","score":0.8579478},{"id":"https://openalex.org/keywords/modulation","display_name":"Modulation (music)","score":0.4434279}],"concepts":[{"id":"https://openalex.org/C2780375056","wikidata":"https://www.wikidata.org/wiki/Q905905","display_name":"Neuromodulation","level":3,"score":0.8579478},{"id":"https://openalex.org/C17755696","wikidata":"https://www.wikidata.org/wiki/Q16564780","display_name":"Ictal","level":3,"score":0.7225966},{"id":"https://openalex.org/C2778542668","wikidata":"https://www.wikidata.org/wiki/Q618076","display_name":"Deep brain stimulation","level":4,"score":0.57966},{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.557909},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5527835},{"id":"https://openalex.org/C148762608","wikidata":"https://www.wikidata.org/wiki/Q3748185","display_name":"Hippocampal formation","level":2,"score":0.53831184},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.47784063},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.44906488},{"id":"https://openalex.org/C123079801","wikidata":"https://www.wikidata.org/wiki/Q750240","display_name":"Modulation (music)","level":2,"score":0.4434279},{"id":"https://openalex.org/C522805319","wikidata":"https://www.wikidata.org/wiki/Q179965","display_name":"Electroencephalography","level":2,"score":0.42418253},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.41813368},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2934652},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.26900032},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.22389978},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.115715206},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.09902075},{"id":"https://openalex.org/C2779734285","wikidata":"https://www.wikidata.org/wiki/Q11085","display_name":"Parkinson's disease","level":3,"score":0.08308855},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":"","qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":"","qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018377","descriptor_name":"Neurotransmitter Agents","qualifier_ui":"","qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012640","descriptor_name":"Seizures","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D000200","descriptor_name":"Action Potentials","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000200","descriptor_name":"Action Potentials","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D046690","descriptor_name":"Deep Brain Stimulation","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008274","descriptor_name":"Magnesium","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008274","descriptor_name":"Magnesium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011188","descriptor_name":"Potassium","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011188","descriptor_name":"Potassium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012640","descriptor_name":"Seizures","qualifier_ui":"","qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"is_oa":false,"landing_page_url":"https://doi.org/10.1142/s0129065711002894","pdf_url":null,"source":{"id":"https://openalex.org/S197665576","display_name":"International Journal of Neural Systems","issn_l":"0129-0657","issn":["0129-0657","1793-6462"],"is_oa":false,"is_in_doaj":false,"is_indexed_in_scopus":true,"is_core":true,"host_organization":"https://openalex.org/P4310319815","host_organization_name":"World Scientific","host_organization_lineage":["https://openalex.org/P4310319815"],"host_organization_lineage_names":["World Scientific"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false},{"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21956930","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_indexed_in_scopus":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":["National Institutes of Health"],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.43,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"grants":[],"datasets":[],"versions":[],"referenced_works_count":41,"referenced_works":["https://openalex.org/W1512741864","https://openalex.org/W1554517915","https://openalex.org/W1901966277","https://openalex.org/W1979819271","https://openalex.org/W1984308387","https://openalex.org/W1985039283","https://openalex.org/W1986518373","https://openalex.org/W1987766637","https://openalex.org/W1989017031","https://openalex.org/W2002883692","https://openalex.org/W2004274357","https://openalex.org/W2004816127","https://openalex.org/W2005023787","https://openalex.org/W2012009068","https://openalex.org/W2013813163","https://openalex.org/W2017549188","https://openalex.org/W2028681020","https://openalex.org/W2029438322","https://openalex.org/W2056651346","https://openalex.org/W2066211612","https://openalex.org/W2075049744","https://openalex.org/W2079156055","https://openalex.org/W2079377440","https://openalex.org/W2099788790","https://openalex.org/W2104960492","https://openalex.org/W2107489108","https://openalex.org/W2122923860","https://openalex.org/W2124337098","https://openalex.org/W2128005859","https://openalex.org/W2135210312","https://openalex.org/W2135629133","https://openalex.org/W2138251100","https://openalex.org/W2158468574","https://openalex.org/W2159398070","https://openalex.org/W2161136893","https://openalex.org/W2167080967","https://openalex.org/W2169166226","https://openalex.org/W2171533361","https://openalex.org/W2282226788","https://openalex.org/W2338172851","https://openalex.org/W2479877058"],"related_works":["https://openalex.org/W622158969","https://openalex.org/W3109080428","https://openalex.org/W2897125999","https://openalex.org/W2790156845","https://openalex.org/W2531482060","https://openalex.org/W2518873333","https://openalex.org/W2376447893","https://openalex.org/W1978747821","https://openalex.org/W1947925357","https://openalex.org/W1568287360"],"abstract_inverted_index":{"Deep":[0],"brain":[1],"stimulation":[2],"(DBS)":[3],"has":[4,17],"been":[5],"noted":[6],"for":[7,134,159],"its":[8],"potential":[9],"to":[10,25,41,72],"suppress":[11],"epileptic":[12],"seizures.":[13],"To":[14],"date,":[15],"DBS":[16],"achieved":[18],"mixed":[19],"results":[20,158],"as":[21,50,55,57],"a":[22,29,111,168],"therapeutic":[23],"approach":[24],"seizure":[26],"control.":[27,126],"Using":[28],"computational":[30],"model,":[31],"we":[32],"demonstrate":[33],"that":[34,84,149],"high-complexity,":[35],"biologically-inspired":[36,153],"responsive":[37],"neuromodulation":[38,45,58],"is":[39],"superior":[40],"periodic":[42,101,142],"forms":[43],"of":[44,97,117,124,152,162,165],"(responsive":[46],"and":[47,61,106,143],"non-responsive)":[48],"such":[49],"those":[51],"implemented":[52],"in":[53,131,167],"DBS,":[54],"well":[56],"using":[59],"random":[60,62,104,107,144],"repetitive-interval":[63],"stimulation.":[64],"We":[65,92],"configured":[66],"radial":[67],"basis":[68],"function":[69],"(RBF)":[70],"networks":[71],"generate":[73],"outputs":[74],"modeling":[75],"interictal":[76,99,137],"time":[77],"series":[78],"recorded":[79],"from":[80],"rodent":[81],"hippocampal":[82],"slices":[83],"were":[85],"perfused":[86],"with":[87],"low":[88],"Mg\u00b2\u207a/high":[89],"K\u207a":[90],"solution.":[91],"then":[93],"compared":[94],"the":[95,135,141,150,160],"performance":[96],"RBF-based":[98],"modulation,":[100,103],"biphasic-pulse":[102],"modulation":[105,109,138],"repetitive":[108],"on":[110],"cognitive":[112],"rhythm":[113],"generator":[114],"(CRG)":[115],"model":[116],"spontaneous":[118],"seizure-like":[119],"events":[120],"(SLEs),":[121],"testing":[122],"efficacy":[123],"SLE":[125,132],"A":[127],"statistically":[128],"significant":[129],"improvement":[130],"mitigation":[133],"RBF":[136],"case":[139],"versus":[140],"cases":[145],"was":[146],"observed,":[147],"suggesting":[148],"use":[151],"neuromodulators":[154],"may":[155],"achieve":[156],"better":[157],"purpose":[161],"electrical":[163],"control":[164],"seizures":[166],"clinical":[169],"setting.":[170]},"abstract_inverted_index_v3":null,"cited_by_api_url":"https://api.openalex.org/works?filter=cites:W2072473279","counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":8},{"year":2012,"cited_by_count":6}],"updated_date":"2025-04-20T19:35:56.703991","created_date":"2016-06-24"}