乐胖代购免代理版

{"id":"https://openalex.org/W3118914527","doi":"https://doi.org/10.1137/20m1324818","title":"The Effects of Fast Inactivation on Conditional First Passage Times of Mortal Diffusive Searchers","display_name":"The Effects of Fast Inactivation on Conditional First Passage Times of Mortal Diffusive Searchers","publication_year":2021,"publication_date":"2021-01-01","ids":{"openalex":"https://openalex.org/W3118914527","doi":"https://doi.org/10.1137/20m1324818","mag":"3118914527"},"language":"en","primary_location":{"is_oa":false,"landing_page_url":"https://doi.org/10.1137/20m1324818","pdf_url":null,"source":{"id":"https://openalex.org/S77200987","display_name":"SIAM Journal on Applied Mathematics","issn_l":"0036-1399","issn":["0036-1399","1095-712X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320508","host_organization_name":"Society for Industrial and Applied Mathematics","host_organization_lineage":["https://openalex.org/P4310320508"],"host_organization_lineage_names":["Society for Industrial and Applied Mathematics"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false},"type":"article","type_crossref":"journal-article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://arxiv.org/pdf/2003.05515","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001461789","display_name":"Sean D. Lawley","orcid":"https://orcid.org/0000-0003-2208-026X"},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sean D. Lawley","raw_affiliation_strings":["Department of Mathematics, University of Utah, Salt Lake City, UT 84112 USA"],"affiliations":[{"raw_affiliation_string":"Department of Mathematics, University of Utah, Salt Lake City, UT 84112 USA","institution_ids":["https://openalex.org/I223532165"]}]}],"institution_assertions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5001461789"],"corresponding_institution_ids":["https://openalex.org/I223532165"],"apc_list":null,"apc_paid":null,"fwci":0.319,"has_fulltext":true,"fulltext_origin":"pdf","cited_by_count":6,"citation_normalized_percentile":{"value":0.638317,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":81,"max":83},"biblio":{"volume":"81","issue":"1","first_page":"1","last_page":"24"},"is_retracted":false,"is_paratext":false,"primary_topic":{"id":"https://openalex.org/T13187","display_name":"Diffusion and Search Dynamics","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T13187","display_name":"Diffusion and Search Dynamics","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10482","display_name":"Mathematical and Theoretical Epidemiology and Ecology Models","score":0.9437,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11152","display_name":"Stochastic processes and statistical mechanics","score":0.9266,"subfield":{"id":"https://openalex.org/subfields/2610","display_name":"Mathematical Physics"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/generality","display_name":"Generality","score":0.70944685},{"id":"https://openalex.org/keywords/conditional-expectation","display_name":"Conditional expectation","score":0.4633506}],"concepts":[{"id":"https://openalex.org/C2780767217","wikidata":"https://www.wikidata.org/wiki/Q5532421","display_name":"Generality","level":2,"score":0.70944685},{"id":"https://openalex.org/C2780990831","wikidata":"https://www.wikidata.org/wiki/Q319141","display_name":"Conjecture","level":2,"score":0.61579025},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.538135},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.5032427},{"id":"https://openalex.org/C79879829","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Intracellular","level":2,"score":0.4740222},{"id":"https://openalex.org/C186215838","wikidata":"https://www.wikidata.org/wiki/Q772232","display_name":"Conditional expectation","level":2,"score":0.4633506},{"id":"https://openalex.org/C36503486","wikidata":"https://www.wikidata.org/wiki/Q11235244","display_name":"Domain (mathematical analysis)","level":2,"score":0.4593883},{"id":"https://openalex.org/C151201525","wikidata":"https://www.wikidata.org/wiki/Q177239","display_name":"Limit (mathematics)","level":2,"score":0.4289516},{"id":"https://openalex.org/C69357855","wikidata":"https://www.wikidata.org/wiki/Q163214","display_name":"Diffusion","level":2,"score":0.4228372},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.40398058},{"id":"https://openalex.org/C118615104","wikidata":"https://www.wikidata.org/wiki/Q121416","display_name":"Discrete mathematics","level":1,"score":0.19135422},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.17590082},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.16913456},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.14091915},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.13277006},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.12486178},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C542102704","wikidata":"https://www.wikidata.org/wiki/Q183257","display_name":"Psychotherapist","level":1,"score":0.0},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"is_oa":false,"landing_page_url":"https://doi.org/10.1137/20m1324818","pdf_url":null,"source":{"id":"https://openalex.org/S77200987","display_name":"SIAM Journal on Applied Mathematics","issn_l":"0036-1399","issn":["0036-1399","1095-712X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320508","host_organization_name":"Society for Industrial and Applied Mathematics","host_organization_lineage":["https://openalex.org/P4310320508"],"host_organization_lineage_names":["Society for Industrial and Applied Mathematics"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false},{"is_oa":true,"landing_page_url":"http://arxiv.org/abs/2003.05515","pdf_url":"http://arxiv.org/pdf/2003.05515","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":["Cornell University"],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false}],"best_oa_location":{"is_oa":true,"landing_page_url":"http://arxiv.org/abs/2003.05515","pdf_url":"http://arxiv.org/pdf/2003.05515","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":["Cornell University"],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false},"sustainable_development_goals":[],"grants":[{"funder":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation","award_id":"DMS-19944574"},{"funder":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation","award_id":"DMS-1148230"},{"funder":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation","award_id":"DMS-1814832"}],"datasets":[],"versions":[],"referenced_works_count":57,"referenced_works":["https://openalex.org/W1533415759","https://openalex.org/W1972811119","https://openalex.org/W1998904894","https://openalex.org/W2019353377","https://openalex.org/W2026956471","https://openalex.org/W2031042504","https://openalex.org/W2035615447","https://openalex.org/W2047002000","https://openalex.org/W2048212809","https://openalex.org/W2049099414","https://openalex.org/W2053012879","https://openalex.org/W2055401277","https://openalex.org/W2057589770","https://openalex.org/W2068540944","https://openalex.org/W2084878223","https://openalex.org/W2091019827","https://openalex.org/W2095481462","https://openalex.org/W2104269878","https://openalex.org/W2134859821","https://openalex.org/W2141542600","https://openalex.org/W2150123411","https://openalex.org/W2161112329","https://openalex.org/W2185008106","https://openalex.org/W2295734324","https://openalex.org/W2303966570","https://openalex.org/W2328156255","https://openalex.org/W2504592056","https://openalex.org/W2557868140","https://openalex.org/W2566119715","https://openalex.org/W2601953622","https://openalex.org/W2621893682","https://openalex.org/W2734967491","https://openalex.org/W2740566218","https://openalex.org/W2762841115","https://openalex.org/W2807411420","https://openalex.org/W2807479273","https://openalex.org/W2809917228","https://openalex.org/W2904659709","https://openalex.org/W2910403159","https://openalex.org/W2914448267","https://openalex.org/W2915598132","https://openalex.org/W2915724401","https://openalex.org/W2917165603","https://openalex.org/W2921842275","https://openalex.org/W2922237678","https://openalex.org/W2922412233","https://openalex.org/W2944823655","https://openalex.org/W2950465077","https://openalex.org/W2954174363","https://openalex.org/W2957860949","https://openalex.org/W2973623668","https://openalex.org/W3102321461","https://openalex.org/W3104094921","https://openalex.org/W3104475981","https://openalex.org/W3104648154","https://openalex.org/W3104882617","https://openalex.org/W3106499528"],"related_works":["https://openalex.org/W4381094582","https://openalex.org/W2369625323","https://openalex.org/W2364579609","https://openalex.org/W2353528968","https://openalex.org/W2045049461","https://openalex.org/W2032776242","https://openalex.org/W1978893398","https://openalex.org/W1977906818","https://openalex.org/W1522139108","https://openalex.org/W1481694090"],"abstract_inverted_index":{"The":[0],"first":[1,11],"time":[2,13],"a":[3,6,10,63,83,174,182],"searcher":[4,23,30,69,119],"finds":[5],"target":[7,75],"is":[8,24,70,106,136,148],"called":[9],"passage":[12],"(FPT).":[14],"In":[15,41,78],"many":[16],"physical,":[17],"chemical,":[18],"and":[19,123,159,170,180],"biological":[20],"processes,":[21],"the":[22,29,39,42,58,68,74,93,100,117,121,124,139,144,186],"\"mortal,\"":[25],"which":[26],"means":[27],"that":[28,52,86,133],"might":[31],"become":[32],"inactivated":[33],"(degrade,":[34],"die,":[35],"etc.)":[36],"before":[37,76],"finding":[38],"target.":[40],"context":[43],"of":[44,62,95,173,188],"intracellular":[45,177,192],"signaling,":[46],"an":[47,88],"important":[48],"recent":[49,168],"work":[50],"discovered":[51],"fast":[53,101],"inactivation":[54,102,135,147],"can":[55],"drastically":[56],"alter":[57],"conditional":[59,97,140],"FPT":[60,141,145],"distribution":[61],"mortal":[64],"diffusive":[65,118],"searcher,":[66],"if":[67,134],"conditioned":[71],"to":[72,143,185],"find":[73],"inactivation.":[77],"this":[79],"paper,":[80],"we":[81],"prove":[82,129],"general":[84,114],"theorem":[85],"yields":[87],"explicit":[89],"formula":[90,105],"for":[91],"all":[92],"moments":[94],"such":[96],"FPTs":[98],"in":[99,130],"limit.":[103],"This":[104],"quite":[107],"universal,":[108],"as":[109],"it":[110],"holds":[111],"under":[112],"very":[113],"conditions":[115],"on":[116,191],"dynamics,":[120],"target,":[122],"spatial":[125,157,189],"domain.":[126],"These":[127],"results":[128,165],"significant":[131],"generality":[132],"fast,":[137],"then":[138],"compared":[142],"without":[146],"(i)":[149],"much":[150,153,161],"faster,":[151],"(ii)":[152],"less":[154,162],"affected":[155],"by":[156],"heterogeneity,":[158],"(iii)":[160],"variable.":[163],"Our":[164],"agree":[166],"with":[167],"computational":[169],"theoretical":[171],"analysis":[172],"certain":[175],"discrete":[176],"diffusion":[178],"model":[179],"confirm":[181],"conjecture":[183],"related":[184],"effect":[187],"heterogeneity":[190],"signaling.":[193]},"cited_by_api_url":"https://api.openalex.org/works?filter=cites:W3118914527","counts_by_year":[{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2}],"updated_date":"2025-01-05T18:44:35.583805","created_date":"2021-01-18"}