乐胖代购免代理版

{"id":"https://openalex.org/W4232113476","doi":"https://doi.org/10.1109/ist.2018.8577087","title":"The analysis of the movement of the genetically modified human skin fibroblasts in culture","display_name":"The analysis of the movement of the genetically modified human skin fibroblasts in culture","publication_year":2018,"publication_date":"2018-10-01","ids":{"openalex":"https://openalex.org/W4232113476","doi":"https://doi.org/10.1109/ist.2018.8577087"},"language":"en","primary_location":{"is_oa":false,"landing_page_url":"https://doi.org/10.1109/ist.2018.8577087","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false},"type":"article","type_crossref":"proceedings-article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5011706410","display_name":"Anna Korzy\u0144ska","orcid":"https://orcid.org/0000-0002-6488-4832"},"institutions":[{"id":"https://openalex.org/I4210164240","display_name":"W\u0142adys\u0142aw Szafer Institute of Botany","ror":"https://ror.org/05p1pn123","country_code":"PL","type":"facility","lineage":["https://openalex.org/I4210164240","https://openalex.org/I99542240"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Anna Korzynska","raw_affiliation_strings":["Nalecz IBBE PAS and WSISIZ under auspices of the PAS, Warsaw, Poland"],"affiliations":[{"raw_affiliation_string":"Nalecz IBBE PAS and WSISIZ under auspices of the PAS, Warsaw, Poland","institution_ids":["https://openalex.org/I4210164240"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000644039","display_name":"Krzysztof Siemion","orcid":"https://orcid.org/0000-0003-2354-9891"},"institutions":[],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Krzysztof Siemion","raw_affiliation_strings":["Nalecz IBBE PAS and Professor Witold Orlowski Public Clinical Hospital, Medical Center for Postgraduate Education Warsaw, Poland"],"affiliations":[{"raw_affiliation_string":"Nalecz IBBE PAS and Professor Witold Orlowski Public Clinical Hospital, Medical Center for Postgraduate Education Warsaw, Poland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032598711","display_name":"Jakub \u017bak","orcid":"https://orcid.org/0000-0003-3826-7846"},"institutions":[],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Jakub Zak","raw_affiliation_strings":["Nalecz IBBE PAS Warsaw, Poland"],"affiliations":[{"raw_affiliation_string":"Nalecz IBBE PAS Warsaw, Poland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042167570","display_name":"\u0141ukasz Roszkowiak","orcid":"https://orcid.org/0000-0002-1878-6588"},"institutions":[],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Lukasz Roszkowiak","raw_affiliation_strings":["Nalecz IBBE PAS Warsaw, Poland"],"affiliations":[{"raw_affiliation_string":"Nalecz IBBE PAS Warsaw, Poland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052980022","display_name":"Agnieszka Wencel","orcid":"https://orcid.org/0000-0003-4582-8250"},"institutions":[],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Agnieszka Wencel","raw_affiliation_strings":["Nalecz IBBE PAS Warsaw, Poland"],"affiliations":[{"raw_affiliation_string":"Nalecz IBBE PAS Warsaw, Poland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086123295","display_name":"Krzysztof Pluta","orcid":"https://orcid.org/0000-0003-1706-2788"},"institutions":[],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Krzysztof Pluta","raw_affiliation_strings":["Nalecz IBBE PAS Warsaw, Poland"],"affiliations":[{"raw_affiliation_string":"Nalecz IBBE PAS Warsaw, Poland","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033324836","display_name":"Dorota G. Pijanowska","orcid":"https://orcid.org/0000-0001-8431-8910"},"institutions":[],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Dorota Pijanowska","raw_affiliation_strings":["Nalecz IBBE PAS Warsaw, Poland"],"affiliations":[{"raw_affiliation_string":"Nalecz IBBE PAS Warsaw, Poland","institution_ids":[]}]}],"institution_assertions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.122,"has_fulltext":true,"fulltext_origin":"ngrams","cited_by_count":1,"citation_normalized_percentile":{"value":0.328287,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":62,"max":70},"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"6"},"is_retracted":false,"is_paratext":false,"primary_topic":{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.9834,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.9834,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11650","display_name":"Skin and Cellular Biology Research","score":0.952,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10505","display_name":"Pluripotent Stem Cells Research","score":0.923,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/crawling","display_name":"Crawling","score":0.43520474}],"concepts":[{"id":"https://openalex.org/C2780381497","wikidata":"https://www.wikidata.org/wiki/Q463418","display_name":"Fibroblast","level":3,"score":0.6236554},{"id":"https://openalex.org/C142613039","wikidata":"https://www.wikidata.org/wiki/Q272983","display_name":"Green fluorescent protein","level":3,"score":0.5842325},{"id":"https://openalex.org/C54009773","wikidata":"https://www.wikidata.org/wiki/Q1429031","display_name":"Transfection","level":3,"score":0.49525967},{"id":"https://openalex.org/C2780226923","wikidata":"https://www.wikidata.org/wiki/Q929848","display_name":"Movement (music)","level":2,"score":0.44457325},{"id":"https://openalex.org/C100368936","wikidata":"https://www.wikidata.org/wiki/Q1411725","display_name":"Crawling","level":2,"score":0.43520474},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.42561153},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.42135698},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.41390324},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.39549074},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.39326715},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.29873508},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.28297555},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2286826},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.20087516},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.16099793},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.15101898},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.11377233},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"is_oa":false,"landing_page_url":"https://doi.org/10.1109/ist.2018.8577087","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Zero hunger","score":0.58,"id":"https://metadata.un.org/sdg/2"}],"grants":[],"datasets":[],"versions":[],"referenced_works_count":17,"referenced_works":["https://openalex.org/W1570052007","https://openalex.org/W1606714264","https://openalex.org/W1969176957","https://openalex.org/W1987346834","https://openalex.org/W1989159677","https://openalex.org/W2000111131","https://openalex.org/W2018495260","https://openalex.org/W2018609975","https://openalex.org/W2041464951","https://openalex.org/W2070218019","https://openalex.org/W2072863216","https://openalex.org/W2073939942","https://openalex.org/W2084044727","https://openalex.org/W2093479340","https://openalex.org/W2122184585","https://openalex.org/W2137572053","https://openalex.org/W2143829617"],"related_works":["https://openalex.org/W4393220254","https://openalex.org/W4390135167","https://openalex.org/W4321258516","https://openalex.org/W4317382653","https://openalex.org/W4287845917","https://openalex.org/W3156164993","https://openalex.org/W3119324922","https://openalex.org/W2385015894","https://openalex.org/W2171573941","https://openalex.org/W2051833850"],"abstract_inverted_index":{"The":[0,58,73,152],"aim":[1],"of":[2,8,11,14,25,34,61,99,123,143,147,154,159,168],"this":[3],"study":[4],"is":[5,137,165],"the":[6,9,104,124,133,141,157],"comparison":[7],"movement":[10,65,75,105,135,155],"various":[12],"types":[13],"human":[15,38],"dermal":[16],"fibroblasts":[17,26,35,110],"with":[18,44,52],"and":[19,29,88,162,178],"without":[20],"genetic":[21],"modification.":[22],"Three":[23],"groups":[24],"were":[27],"cultured":[28],"monitored:":[30],"(1)":[31,79],"control":[32],"group":[33],"isolated":[36],"from":[37],"skin":[39],"(not":[40],"transduced);":[41],"(2)":[42,86],"transduced":[43,51],"lentivirus":[45,53],"bearing":[46,54],"EGFP":[47],"fluorescent":[48,56],"marker;":[49],"(3)":[50,97],"DsRed2":[55],"marker.":[57],"experimental":[59],"sequences":[60],"images":[62],"documenting":[63],"cells'":[64,74,171],"have":[66,127],"been":[67,128],"analyzed":[68],"using":[69],"image":[70],"processing":[71],"methods.":[72],"was":[76],"described":[77],"by:":[78],"distance":[80,87,160],"between":[81],"each":[82,92,112],"two":[83],"consecutive":[84],"images/frames,":[85],"displacement":[89],"covered":[90,161],"by":[91,140],"fibroblast":[93],"in":[94,111,156,170],"30":[95],"minutes":[96],"length":[98,122],"cell":[100],"crawling":[101],"cycle,":[102],"(4)":[103],"tortuosity":[106],"coefficient":[107],"for":[108],"all":[109],"group.":[113],"Also":[114],"shape":[115],"features":[116],"such":[117],"as:":[118],"area,":[119],"perimeter,":[120],"eccentricity,":[121],"major":[125],"axis":[126],"analyzed.":[129],"It":[130],"appears":[131],"that":[132],"general":[134],"behavior":[136],"not":[138],"changed":[139],"process":[142],"transduction":[144],"but":[145],"some":[146],"its":[148],"aspects":[149],"are":[150,175],"modified.":[151],"efficiency":[153],"sense":[158],"region":[163],"penetration":[164],"decreased":[166],"because":[167],"changes":[169],"morphology.":[172],"Transduced":[173],"cells":[174],"less":[176],"polarized":[177],"develop":[179],"extra":[180],"podia":[181],"during":[182],"their":[183],"crawling.":[184]},"cited_by_api_url":"https://api.openalex.org/works?filter=cites:W4232113476","counts_by_year":[{"year":2019,"cited_by_count":1}],"updated_date":"2025-01-16T04:00:35.034412","created_date":"2022-05-12"}