{"id":"https://openalex.org/W2141368685","doi":"https://doi.org/10.1109/enc.2005.30","title":"Optimal Artificial Chemistries and Metabolic Pathways","display_name":"Optimal Artificial Chemistries and Metabolic Pathways","publication_year":2006,"publication_date":"2006-02-15","ids":{"openalex":"https://openalex.org/W2141368685","doi":"https://doi.org/10.1109/enc.2005.30","mag":"2141368685"},"language":"en","primary_location":{"is_oa":false,"landing_page_url":"https://doi.org/10.1109/enc.2005.30","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false},"type":"article","type_crossref":"proceedings-article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032286936","display_name":"Liliana F\u00e9lix","orcid":null},"institutions":[{"id":"https://openalex.org/I97750245","display_name":"Software (Spain)","ror":"https://ror.org/02ethns06","country_code":"ES","type":"company","lineage":["https://openalex.org/I4210087817","https://openalex.org/I97750245"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"L. Felix","raw_affiliation_strings":["Dept. of Software, Tech. Univ. of Catalonia, Barcelona, Spain"],"affiliations":[{"raw_affiliation_string":"Dept. of Software, Tech. Univ. of Catalonia, Barcelona, Spain","institution_ids":["https://openalex.org/I97750245"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005629452","display_name":"Gabriel Valiente","orcid":"https://orcid.org/0000-0001-9194-2703"},"institutions":[{"id":"https://openalex.org/I9617848","display_name":"Universitat Polit\u00e8cnica de Catalunya","ror":"https://ror.org/03mb6wj31","country_code":"ES","type":"education","lineage":["https://openalex.org/I9617848"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"G. Valiente","raw_affiliation_strings":["Technical Univ. of Catalonia; Barcelona Spain"],"affiliations":[{"raw_affiliation_string":"Technical Univ. of Catalonia; Barcelona Spain","institution_ids":["https://openalex.org/I9617848"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087466847","display_name":"Francesc Rossell\u00f3","orcid":"https://orcid.org/0000-0003-2897-5398"},"institutions":[{"id":"https://openalex.org/I50441567","display_name":"Universitat de les Illes Balears","ror":"https://ror.org/03e10x626","country_code":"ES","type":"education","lineage":["https://openalex.org/I50441567"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"F. Rossello","raw_affiliation_strings":["University of the Balearic Islands Palma de Mallorca Spain"],"affiliations":[{"raw_affiliation_string":"University of the Balearic Islands Palma de Mallorca Spain","institution_ids":["https://openalex.org/I50441567"]}]}],"institution_assertions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.329,"has_fulltext":true,"fulltext_origin":"ngrams","cited_by_count":5,"citation_normalized_percentile":{"value":0.673311,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":76,"max":78},"biblio":{"volume":null,"issue":null,"first_page":"298","last_page":"305"},"is_retracted":false,"is_paratext":false,"primary_topic":{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9965,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9965,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9935,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11445","display_name":"Origins and Evolution of Life","score":0.9879,"subfield":{"id":"https://openalex.org/subfields/3103","display_name":"Astronomy and Astrophysics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/molecular-graph","display_name":"Molecular graph","score":0.42181325},{"id":"https://openalex.org/keywords/chemical-transformation","display_name":"Chemical transformation","score":0.4210924}],"concepts":[{"id":"https://openalex.org/C177801218","wikidata":"https://www.wikidata.org/wiki/Q36534","display_name":"Chemical reaction","level":2,"score":0.66457367},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5293867},{"id":"https://openalex.org/C132525143","wikidata":"https://www.wikidata.org/wiki/Q141488","display_name":"Graph","level":2,"score":0.45756796},{"id":"https://openalex.org/C2780022179","wikidata":"https://www.wikidata.org/wiki/Q1986794","display_name":"Molecular graph","level":3,"score":0.42181325},{"id":"https://openalex.org/C2780759640","wikidata":"https://www.wikidata.org/wiki/Q36534","display_name":"Chemical transformation","level":2,"score":0.4210924},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4181376},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.41785365},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.33819026},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.287811},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.12898871},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"is_oa":false,"landing_page_url":"https://doi.org/10.1109/enc.2005.30","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false}],"best_oa_location":null,"sustainable_development_goals":[],"grants":[],"datasets":[],"versions":[],"referenced_works_count":17,"referenced_works":["https://openalex.org/W1532115155","https://openalex.org/W1568509792","https://openalex.org/W1916753417","https://openalex.org/W1975147762","https://openalex.org/W1979537657","https://openalex.org/W1999638776","https://openalex.org/W2014348203","https://openalex.org/W2034994407","https://openalex.org/W2038702914","https://openalex.org/W2055677741","https://openalex.org/W2077608374","https://openalex.org/W2107808084","https://openalex.org/W2113221321","https://openalex.org/W2132232959","https://openalex.org/W2141368685","https://openalex.org/W2145600675","https://openalex.org/W90410463"],"related_works":["https://openalex.org/W4245806825","https://openalex.org/W4230934951","https://openalex.org/W3172744229","https://openalex.org/W3021233280","https://openalex.org/W2981423934","https://openalex.org/W2885630566","https://openalex.org/W2808877228","https://openalex.org/W2624499382","https://openalex.org/W2058409805","https://openalex.org/W2013842271"],"abstract_inverted_index":{"Metabolism":[0],"can":[1],"be":[2],"regarded":[3],"as":[4,34,92,109,118,175],"a":[5,21,35,40,46,54,93,131,136,141,167],"network":[6],"of":[7,24,37,39,42,48,56,64,104,113,144,155,169],"biochemical":[8],"reactions,":[9,25],"connected":[10],"via":[11],"their":[12],"substrates":[13],"and":[14,26,78,106,111],"products.":[15],"A":[16],"metabolic":[17,79,173],"pathway":[18],"is":[19,28,58,90],"thus":[20],"coordinated":[22],"series":[23],"it":[27],"often":[29],"described":[30,59,73],"in":[31,172],"symbolic":[32],"terms,":[33],"succession":[36],"transformations":[38],"set":[41,47,55,143],"substrate":[43,105,132],"molecules":[44,57,108],"into":[45],"product":[49,107,137],"molecules.":[50],"In":[51],"this":[52],"paper,":[53],"by":[60,74,84],"the":[61,65,97,102,114,150],"disjoint":[62],"union":[63],"chemical":[66,70,75,98,115,133,138,145,156,170],"graphs":[67,99,117,147],"representing":[68],"them,":[69],"reactions":[71,171],"are":[72,81,158,164],"reaction":[76,116,146],"graphs,":[77],"pathways":[80,174],"computationally":[82],"modeled":[83],"artificial":[85,88,127],"chemistries.":[86],"An":[87],"chemistry":[89],"represented":[91],"directed":[94],"graph":[95,134,139],"with":[96],"that":[100,149],"represent":[101],"sets":[103],"nodes":[110],"applications":[112],"arcs.":[119],"We":[120],"present":[121],"simple":[122],"algorithms":[123,163],"for":[124],"building":[125],"optimal":[126],"chemistries,":[128],"which":[129],"transform":[130],"to":[135],"using":[140],"given":[142],"such":[148],"least":[151],"possible":[152],"total":[153],"number":[154],"bonds":[157],"created":[159],"or":[160,180],"broken.":[161],"These":[162],"based":[165],"on":[166],"classification":[168],"either":[176],"decomposition,":[177],"pseudo-exchange,":[178],"displacement,":[179],"isomerase":[181],"reactions.":[182]},"cited_by_api_url":"https://api.openalex.org/works?filter=cites:W2141368685","counts_by_year":[{"year":2012,"cited_by_count":2}],"updated_date":"2024-12-17T17:08:56.004715","created_date":"2016-06-24"}