乐胖代购免代理版

{"id":"https://openalex.org/W3005912229","doi":"https://doi.org/10.1109/bibm49941.2020.9313463","title":"Simulating an Immune Response with a Combined Agent-Based Model of a Triple-Negative Breast Cancer Tumor and Vascular Network","display_name":"Simulating an Immune Response with a Combined Agent-Based Model of a Triple-Negative Breast Cancer Tumor and Vascular Network","publication_year":2020,"publication_date":"2020-12-16","ids":{"openalex":"https://openalex.org/W3005912229","doi":"https://doi.org/10.1109/bibm49941.2020.9313463","mag":"3005912229"},"language":"en","primary_location":{"is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm49941.2020.9313463","pdf_url":null,"source":{"id":"https://openalex.org/S4363607735","display_name":"2021 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_indexed_in_scopus":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false},"type":"article","type_crossref":"proceedings-article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5014000485","display_name":"Michael Ventoso","orcid":null},"institutions":[{"id":"https://openalex.org/I39661318","display_name":"Bard College","ror":"https://ror.org/04yrgt058","country_code":"US","type":"funder","lineage":["https://openalex.org/I39661318"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael Ventoso","raw_affiliation_strings":["Division of Science, Mathematics, and Computing, Bard College, Annandale-on-Hudson, United States"],"affiliations":[{"raw_affiliation_string":"Division of Science, Mathematics, and Computing, Bard College, Annandale-on-Hudson, United States","institution_ids":["https://openalex.org/I39661318"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086551877","display_name":"Kerri\u2010Ann Norton","orcid":"https://orcid.org/0000-0003-1002-9467"},"institutions":[{"id":"https://openalex.org/I39661318","display_name":"Bard College","ror":"https://ror.org/04yrgt058","country_code":"US","type":"funder","lineage":["https://openalex.org/I39661318"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kerri-Ann Norton","raw_affiliation_strings":["Division of Science, Mathematics, and Computing, Bard College, Annandale-on-Hudson, United States"],"affiliations":[{"raw_affiliation_string":"Division of Science, Mathematics, and Computing, Bard College, Annandale-on-Hudson, United States","institution_ids":["https://openalex.org/I39661318"]}]}],"institution_assertions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.695,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.665615,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":76,"max":78},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"primary_topic":{"id":"https://openalex.org/T11829","display_name":"Mathematical Biology Tumor Growth","score":0.9993,"subfield":{"id":"https://openalex.org/subfields/2611","display_name":"Modeling and Simulation"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11829","display_name":"Mathematical Biology Tumor Growth","score":0.9993,"subfield":{"id":"https://openalex.org/subfields/2611","display_name":"Modeling and Simulation"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.9977,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.9974,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/triple-negative-breast-cancer","display_name":"Triple-negative breast cancer","score":0.7039175},{"id":"https://openalex.org/keywords/ctl*","display_name":"CTL*","score":0.67490685}],"concepts":[{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.7188597},{"id":"https://openalex.org/C2780110267","wikidata":"https://www.wikidata.org/wiki/Q7843332","display_name":"Triple-negative breast cancer","level":4,"score":0.7039175},{"id":"https://openalex.org/C147969180","wikidata":"https://www.wikidata.org/wiki/Q5014579","display_name":"CTL*","level":4,"score":0.67490685},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6379833},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.5971601},{"id":"https://openalex.org/C2776107976","wikidata":"https://www.wikidata.org/wiki/Q1786433","display_name":"Tumor microenvironment","level":3,"score":0.49401218},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.49208802},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.48941174},{"id":"https://openalex.org/C3020616263","wikidata":"https://www.wikidata.org/wiki/Q1216998","display_name":"Tumor cells","level":2,"score":0.44036868},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.4224495},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4038961},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.37026477},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.32037926},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2506953},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.08657879},{"id":"https://openalex.org/C167672396","wikidata":"https://www.wikidata.org/wiki/Q417800","display_name":"CD8","level":3,"score":0.0590221},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm49941.2020.9313463","pdf_url":null,"source":{"id":"https://openalex.org/S4363607735","display_name":"2021 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_indexed_in_scopus":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.82,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"grants":[],"datasets":[],"versions":[],"referenced_works_count":31,"referenced_works":["https://openalex.org/W1833179633","https://openalex.org/W1972739162","https://openalex.org/W1985804036","https://openalex.org/W1992514491","https://openalex.org/W2016671320","https://openalex.org/W2017045714","https://openalex.org/W2046045754","https://openalex.org/W2092476887","https://openalex.org/W2096151993","https://openalex.org/W2103390588","https://openalex.org/W2107583561","https://openalex.org/W2108202680","https://openalex.org/W2111220263","https://openalex.org/W2116455112","https://openalex.org/W2117692326","https://openalex.org/W2134362149","https://openalex.org/W2137074525","https://openalex.org/W2141102490","https://openalex.org/W2142621481","https://openalex.org/W2150704630","https://openalex.org/W2168685702","https://openalex.org/W2171998177","https://openalex.org/W2314203153","https://openalex.org/W2551818288","https://openalex.org/W2561642944","https://openalex.org/W2734569735","https://openalex.org/W2801459582","https://openalex.org/W2804842145","https://openalex.org/W2897422388","https://openalex.org/W2901513648","https://openalex.org/W2906815954"],"related_works":["https://openalex.org/W3187751359","https://openalex.org/W2361233661","https://openalex.org/W2358141151","https://openalex.org/W2347258828","https://openalex.org/W2139048705","https://openalex.org/W2133374731","https://openalex.org/W1971118974","https://openalex.org/W1782288177","https://openalex.org/W1605884721","https://openalex.org/W1549922507"],"abstract_inverted_index":{"Cytotoxic":[0],"T-cells":[1],"(CTLs)":[2],"are":[3,108],"one":[4],"mechanism":[5],"the":[6,34,41,69,79,90,102,105,120],"immune":[7],"system":[8],"employs":[9],"to":[10,29,115],"eliminate":[11],"cancer":[12,28,55],"cells.":[13],"In":[14],"this":[15],"study,":[16],"we":[17],"expand":[18],"upon":[19],"a":[20,37,47],"previous":[21],"3-dimensional":[22],"agent-based":[23],"model":[24,44],"of":[25,36,46,52,72,76,104],"triple-negative":[26,48],"breast":[27,49],"include":[30],"an":[31,63],"immuno-therapy":[32],"in":[33,89,119],"form":[35],"CTL":[38],"insertion":[39],"into":[40,78],"tumor.":[42],"The":[43,95],"consists":[45],"tumor,":[50],"comprised":[51],"progenitor":[53],"cells,":[54,57],"stem":[56],"tumor-associated":[58],"macrophages,":[59],"as":[60,62],"well":[61],"expanding":[64],"vascular":[65],"network.":[66],"We":[67],"investigate":[68],"treatment":[70],"effects":[71],"inserting":[73],"different":[74],"numbers":[75],"CTLs":[77,100],"tumor":[80,87,106,117],"microenvironment,":[81],"and":[82,92],"their":[83],"overall":[84],"effect":[85],"on":[86],"size":[88,103],"short":[91],"longer":[93],"terms.":[94],"results":[96],"show":[97],"that":[98],"while":[99],"decrease":[101],"they":[107],"ineffective":[109],"at":[110],"completely":[111],"eliminating":[112],"it,":[113],"leading":[114],"continued":[116],"proliferation":[118],"aftermath.":[121]},"abstract_inverted_index_v3":null,"cited_by_api_url":"https://api.openalex.org/works?filter=cites:W3005912229","counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1}],"updated_date":"2025-04-23T21:29:15.030539","created_date":"2020-02-24"}