{"id":"https://openalex.org/W2110639052","doi":"https://doi.org/10.1109/10.915706","title":"The effects of interpulse interval on stochastic properties of electrical stimulation: models and measurements","display_name":"The effects of interpulse interval on stochastic properties of electrical stimulation: models and measurements","publication_year":2001,"publication_date":"2001-04-01","ids":{"openalex":"https://openalex.org/W2110639052","doi":"https://doi.org/10.1109/10.915706","mag":"2110639052","pmid":"https://pubmed.ncbi.nlm.nih.gov/11322529"},"language":"en","primary_location":{"is_oa":false,"landing_page_url":"https://doi.org/10.1109/10.915706","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false},"type":"article","type_crossref":"journal-article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034747744","display_name":"Akihiro J. Matsuoka","orcid":"https://orcid.org/0000-0002-1066-6514"},"institutions":[{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A.J. Matsuoka","raw_affiliation_strings":["Dept. of Otolaryngology-Head & Neck Surg., Iowa Univ., Iowa City, IA, USA"],"affiliations":[{"raw_affiliation_string":"Dept. of Otolaryngology-Head & Neck Surg., Iowa Univ., Iowa City, IA, USA","institution_ids":["https://openalex.org/I126307644"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011643678","display_name":"Jay T. Rubinstein","orcid":null},"institutions":[{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J.T. Rubinstein","raw_affiliation_strings":["[Department of Otolaryngology-Head and Neck Surgery and the Department of Physiology and Biophysics, University of Iowa, Iowa, IA, USA]"],"affiliations":[{"raw_affiliation_string":"[Department of Otolaryngology-Head and Neck Surgery and the Department of Physiology and Biophysics, University of Iowa, Iowa, IA, USA]","institution_ids":["https://openalex.org/I126307644"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110219076","display_name":"Paul J. Abbas","orcid":null},"institutions":[{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P.J. Abbas","raw_affiliation_strings":["University of Iowa, ."],"affiliations":[{"raw_affiliation_string":"University of Iowa, .","institution_ids":["https://openalex.org/I126307644"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052202815","display_name":"Charles A. Miller","orcid":"https://orcid.org/0000-0002-3813-1706"},"institutions":[{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C.A. Miller","raw_affiliation_strings":["University of Iowa, ."],"affiliations":[{"raw_affiliation_string":"University of Iowa, .","institution_ids":["https://openalex.org/I126307644"]}]}],"institution_assertions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.666,"has_fulltext":true,"fulltext_origin":"ngrams","cited_by_count":48,"citation_normalized_percentile":{"value":0.920083,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":92},"biblio":{"volume":"48","issue":"4","first_page":"416","last_page":"424"},"is_retracted":false,"is_paratext":false,"primary_topic":{"id":"https://openalex.org/T11513","display_name":"stochastic dynamics and bifurcation","score":0.9958,"subfield":{"id":"https://openalex.org/subfields/3109","display_name":"Statistical and Nonlinear Physics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11513","display_name":"stochastic dynamics and bifurcation","score":0.9958,"subfield":{"id":"https://openalex.org/subfields/3109","display_name":"Statistical and Nonlinear Physics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10283","display_name":"Hearing Loss and Rehabilitation","score":0.9952,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10323","display_name":"Analog and Mixed-Signal Circuit Design","score":0.9932,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/basilar-membrane","display_name":"Basilar membrane","score":0.4302771},{"id":"https://openalex.org/keywords/action-potential","display_name":"Action potential","score":0.41778684}],"concepts":[{"id":"https://openalex.org/C2778882171","wikidata":"https://www.wikidata.org/wiki/Q724965","display_name":"Cochlear implant","level":2,"score":0.8184161},{"id":"https://openalex.org/C70616116","wikidata":"https://www.wikidata.org/wiki/Q1736732","display_name":"Refractory period","level":2,"score":0.63400906},{"id":"https://openalex.org/C50952357","wikidata":"https://www.wikidata.org/wiki/Q424960","display_name":"Sodium channel","level":3,"score":0.51977986},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.5046836},{"id":"https://openalex.org/C17525397","wikidata":"https://www.wikidata.org/wiki/Q176140","display_name":"Electrode","level":2,"score":0.49065247},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.44251227},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.43420076},{"id":"https://openalex.org/C2780807236","wikidata":"https://www.wikidata.org/wiki/Q3503790","display_name":"Basilar membrane","level":3,"score":0.4302771},{"id":"https://openalex.org/C54407271","wikidata":"https://www.wikidata.org/wiki/Q194277","display_name":"Action potential","level":3,"score":0.41778684},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.3124339},{"id":"https://openalex.org/C2780130748","wikidata":"https://www.wikidata.org/wiki/Q317857","display_name":"Cochlea","level":2,"score":0.28000516},{"id":"https://openalex.org/C185263204","wikidata":"https://www.wikidata.org/wiki/Q1154774","display_name":"Electrophysiology","level":2,"score":0.27159476},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.23665026},{"id":"https://openalex.org/C537181965","wikidata":"https://www.wikidata.org/wiki/Q658","display_name":"Sodium","level":2,"score":0.20740795},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.17540258},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.14280263},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.108073205},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000200","descriptor_name":"Action Potentials","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D005071","descriptor_name":"Evoked Potentials","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":"","qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015222","descriptor_name":"Sodium Channels","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000200","descriptor_name":"Action Potentials","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002415","descriptor_name":"Cats","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003054","descriptor_name":"Cochlear Implants","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017097","descriptor_name":"Electric Impedance","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004558","descriptor_name":"Electric Stimulation","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005071","descriptor_name":"Evoked Potentials","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017711","descriptor_name":"Nonlinear Dynamics","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011901","descriptor_name":"Ranvier's Nodes","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011901","descriptor_name":"Ranvier's Nodes","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012815","descriptor_name":"Signal Processing, Computer-Assisted","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015222","descriptor_name":"Sodium Channels","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013067","descriptor_name":"Speech Perception","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013067","descriptor_name":"Speech Perception","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013269","descriptor_name":"Stochastic Processes","qualifier_ui":"","qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"is_oa":false,"landing_page_url":"https://doi.org/10.1109/10.915706","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false},{"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11322529","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":["National Institutes of Health"],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false}],"best_oa_location":null,"sustainable_development_goals":[],"grants":[],"datasets":[],"versions":[],"referenced_works_count":32,"referenced_works":["https://openalex.org/W1490311173","https://openalex.org/W170956802","https://openalex.org/W1969696477","https://openalex.org/W1970957195","https://openalex.org/W1972912532","https://openalex.org/W1974303879","https://openalex.org/W1975696802","https://openalex.org/W1995612370","https://openalex.org/W2003180943","https://openalex.org/W2013793655","https://openalex.org/W2017118980","https://openalex.org/W2017444605","https://openalex.org/W2025881996","https://openalex.org/W2029010014","https://openalex.org/W2036645640","https://openalex.org/W2037450165","https://openalex.org/W2038010140","https://openalex.org/W2038914534","https://openalex.org/W2057204023","https://openalex.org/W2061905631","https://openalex.org/W2062292438","https://openalex.org/W2069121426","https://openalex.org/W2071245802","https://openalex.org/W2081033522","https://openalex.org/W2092520818","https://openalex.org/W2099654960","https://openalex.org/W2124398758","https://openalex.org/W2132584748","https://openalex.org/W2135336682","https://openalex.org/W2142575696","https://openalex.org/W2175672411","https://openalex.org/W2182904977"],"related_works":["https://openalex.org/W4293879676","https://openalex.org/W3149003477","https://openalex.org/W2413130072","https://openalex.org/W2361564635","https://openalex.org/W2105403855","https://openalex.org/W2067421539","https://openalex.org/W1994326065","https://openalex.org/W1972542152","https://openalex.org/W1971971342","https://openalex.org/W1908391790"],"abstract_inverted_index":{"It":[0],"is":[1,88,150,174],"known":[2],"that":[3],"some":[4],"cochlear":[5,225],"implant":[6,226],"users":[7],"have":[8,41,180,200,217],"improved":[9],"speech":[10,221],"perception":[11],"using":[12,49,184],"higher":[13],"rates":[14],"of":[15,45,59,62,171,205,237],"interleaved":[16],"pulsatile":[17],"stimulation.":[18],"There":[19],"are,":[20],"however,":[21],"significant":[22,218],"limitations":[23],"on":[24,196],"their":[25],"performance":[26],"presumably":[27],"due":[28],"in":[29,203,223],"part":[30],"to":[31,73,165],"temporal":[32],"and":[33,53,95,102,124,134,190,199],"spatial":[34],"interactions.":[35],"To":[36],"address":[37],"these":[38],"limitations,":[39],"we":[40],"examined":[42],"refractory":[43],"characteristics":[44],"the":[46,60,75,111,137,155,169,182,197,211],"auditory":[47],"nerve":[48,198],"experimental":[50],"animal":[51],"models":[52],"computational":[54],"simulations.":[55],"A":[56],"stochastic":[57],"model":[58,87],"node":[61],"Ranvier":[63],"modified":[64],"for":[65,80,117,127,145,220,234],"mammalian":[66],"sodium":[67,93],"channel":[68],"kinetics":[69],"has":[70],"been":[71],"developed":[72],"calculate":[74],"masked":[76],"input-output":[77],"(I/O)":[78],"functions":[79,113,208],"different":[81,119],"interpulse":[82],"intervals":[83],"(IPI)":[84],"[26].":[85],"The":[86,104],"based":[89],"upon":[90],"1000":[91],"voltage-gated":[92],"channels":[94],"incorporates":[96],"parameters":[97],"such":[98],"as":[99],"nodal":[100],"resistance":[101],"capacitance.":[103],"relative":[105],"spread":[106],"(RS)":[107],"[35]":[108],"calculated":[109],"from":[110],"I/O":[112],"was":[114,139],"typically":[115],"0.03":[116],"17":[118],"IPIs":[120],"between":[121],"450":[122],"micros":[123],"6":[125],"ms":[126],"cathodal":[128],"stimuli.":[129],"For":[130],"IPI":[131],"=":[132],"830":[133],"870":[135],"micros,":[136],"RS":[138,170,213],"ten":[140],"times":[141],"greater":[142],"than":[143],"those":[144],"other":[146],"IPIs.":[147],"Although":[148],"it":[149],"not":[151],"fully":[152],"understood":[153],"how":[154],"electrically":[156],"evoked":[157],"compound":[158],"action":[159],"potential":[160],"(EAP)":[161],"data":[162],"are":[163],"related":[164],"single":[166,172],"fiber":[167],"data,":[168],"fibers":[173],"a":[175,185,191,224],"partial":[176],"contributor":[177],"[19].":[178],"We":[179],"measured":[181],"EAP":[183,206],"monopolar":[186],"intracochlear":[187],"stimulating":[188],"electrode":[189,193],"recording":[192],"placed":[194],"directly":[195],"observed":[201],"changes":[202],"slope":[204],"growth":[207],"consistent":[209],"with":[210],"theoretical":[212],"values.":[214],"These":[215],"results":[216],"implications":[219],"coding":[222],"since":[227],"they":[228],"suggest":[229],"an":[230],"increased":[231],"membrane":[232],"noise":[233],"pulse":[235],"trains":[236],"specific":[238],"rates.":[239]},"cited_by_api_url":"https://api.openalex.org/works?filter=cites:W2110639052","counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2025-01-07T11:21:40.607006","created_date":"2016-06-24"}