{"id":"https://openalex.org/W4404522100","doi":"https://doi.org/10.1016/j.neuroimage.2024.120948","title":"Sex Differences of Negative Emotions in Adults and Infants Along the Prefrontal-Amygdaloid Brain Pathway","display_name":"Sex Differences of Negative Emotions in Adults and Infants Along the Prefrontal-Amygdaloid Brain Pathway","publication_year":2024,"publication_date":"2024-11-01","ids":{"openalex":"https://openalex.org/W4404522100","doi":"https://doi.org/10.1016/j.neuroimage.2024.120948","pmid":"https://pubmed.ncbi.nlm.nih.gov/39571642"},"language":"en","primary_location":{"is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neuroimage.2024.120948","pdf_url":null,"source":{"id":"https://openalex.org/S103225281","display_name":"NeuroImage","issn_l":"1053-8119","issn":["1053-8119","1095-9572"],"is_oa":true,"is_in_doaj":true,"is_indexed_in_scopus":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true},"type":"article","type_crossref":"journal-article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1016/j.neuroimage.2024.120948","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053751577","display_name":"Leiming Wu","orcid":"https://orcid.org/0000-0003-0229-9491"},"institutions":[{"id":"https://openalex.org/I149594827","display_name":"Xidian University","ror":"https://ror.org/05s92vm98","country_code":"CN","type":"funder","lineage":["https://openalex.org/I149594827"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Leiming Wu","raw_affiliation_strings":["School of Life Science and Technology, Xidian University, Xi'an, Shaanxi, China; Xi'an Key Laboratory of Intelligent Sensing and Regulation of trans-Scale Life Information, Xidian University, Xi'an, Shaanxi, China."],"affiliations":[{"raw_affiliation_string":"School of Life Science and Technology, Xidian University, Xi'an, Shaanxi, China; Xi'an Key Laboratory of Intelligent Sensing and Regulation of trans-Scale Life Information, Xidian University, Xi'an, Shaanxi, China.","institution_ids":["https://openalex.org/I149594827"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076713206","display_name":"Zilong Hong","orcid":null},"institutions":[{"id":"https://openalex.org/I149594827","display_name":"Xidian University","ror":"https://ror.org/05s92vm98","country_code":"CN","type":"funder","lineage":["https://openalex.org/I149594827"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zilong Hong","raw_affiliation_strings":["School of Life Science and Technology, Xidian University, Xi'an, Shaanxi, China; Xi'an Key Laboratory of Intelligent Sensing and Regulation of trans-Scale Life Information, Xidian University, Xi'an, Shaanxi, China."],"affiliations":[{"raw_affiliation_string":"School of Life Science and Technology, Xidian University, Xi'an, Shaanxi, China; Xi'an Key Laboratory of Intelligent Sensing and Regulation of trans-Scale Life Information, Xidian University, Xi'an, Shaanxi, China.","institution_ids":["https://openalex.org/I149594827"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100602078","display_name":"Shujun Wang","orcid":"https://orcid.org/0000-0003-1454-4335"},"institutions":[{"id":"https://openalex.org/I149594827","display_name":"Xidian University","ror":"https://ror.org/05s92vm98","country_code":"CN","type":"funder","lineage":["https://openalex.org/I149594827"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shujun Wang","raw_affiliation_strings":["School of Life Science and Technology, Xidian University, Xi'an, Shaanxi, China; Xi'an Key Laboratory of Intelligent Sensing and Regulation of trans-Scale Life Information, Xidian University, Xi'an, Shaanxi, China."],"affiliations":[{"raw_affiliation_string":"School of Life Science and Technology, Xidian University, Xi'an, Shaanxi, China; Xi'an Key Laboratory of Intelligent Sensing and Regulation of trans-Scale Life Information, Xidian University, Xi'an, Shaanxi, China.","institution_ids":["https://openalex.org/I149594827"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103339993","display_name":"Jia Huang","orcid":null},"institutions":[{"id":"https://openalex.org/I149594827","display_name":"Xidian University","ror":"https://ror.org/05s92vm98","country_code":"CN","type":"funder","lineage":["https://openalex.org/I149594827"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jia Huang","raw_affiliation_strings":["School of Life Science and Technology, Xidian University, Xi'an, Shaanxi, China; Xi'an Key Laboratory of Intelligent Sensing and Regulation of trans-Scale Life Information, Xidian University, Xi'an, Shaanxi, China."],"affiliations":[{"raw_affiliation_string":"School of Life Science and Technology, Xidian University, Xi'an, Shaanxi, China; Xi'an Key Laboratory of Intelligent Sensing and Regulation of trans-Scale Life Information, Xidian University, Xi'an, Shaanxi, China.","institution_ids":["https://openalex.org/I149594827"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101957662","display_name":"Jixin Liu","orcid":"https://orcid.org/0000-0002-4239-1201"},"institutions":[{"id":"https://openalex.org/I149594827","display_name":"Xidian University","ror":"https://ror.org/05s92vm98","country_code":"CN","type":"funder","lineage":["https://openalex.org/I149594827"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jixin Liu","raw_affiliation_strings":["School of Life Science and Technology, Xidian University, Xi'an, Shaanxi, China; Xi'an Key Laboratory of Intelligent Sensing and Regulation of trans-Scale Life Information, Xidian University, Xi'an, Shaanxi, China. Electronic address: liujixin@xidian.edu.cn."],"affiliations":[{"raw_affiliation_string":"School of Life Science and Technology, Xidian University, Xi'an, Shaanxi, China; Xi'an Key Laboratory of Intelligent Sensing and Regulation of trans-Scale Life Information, Xidian University, Xi'an, Shaanxi, China. Electronic address: liujixin@xidian.edu.cn.","institution_ids":["https://openalex.org/I149594827"]}]}],"institution_assertions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3450,"currency":"USD","value_usd":3450},"apc_paid":{"value":3450,"currency":"USD","value_usd":3450},"fwci":0.984,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.702456,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":76,"max":87},"biblio":{"volume":null,"issue":null,"first_page":"120948","last_page":"120948"},"is_retracted":false,"is_paratext":false,"primary_topic":{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.9972,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.9972,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9962,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10182","display_name":"Child and Adolescent Psychosocial and Emotional Development","score":0.996,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[],"concepts":[{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.6623831},{"id":"https://openalex.org/C2781195155","wikidata":"https://www.wikidata.org/wiki/Q18680","display_name":"Prefrontal cortex","level":3,"score":0.48193192},{"id":"https://openalex.org/C138496976","wikidata":"https://www.wikidata.org/wiki/Q175002","display_name":"Developmental psychology","level":1,"score":0.42316842},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.41233003},{"id":"https://openalex.org/C180747234","wikidata":"https://www.wikidata.org/wiki/Q23373","display_name":"Cognitive psychology","level":1,"score":0.37448347},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.102692485}],"mesh":[],"locations_count":2,"locations":[{"is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neuroimage.2024.120948","pdf_url":null,"source":{"id":"https://openalex.org/S103225281","display_name":"NeuroImage","issn_l":"1053-8119","issn":["1053-8119","1095-9572"],"is_oa":true,"is_in_doaj":true,"is_indexed_in_scopus":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true},{"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39571642","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_indexed_in_scopus":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":["National Institutes of Health"],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false}],"best_oa_location":{"is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neuroimage.2024.120948","pdf_url":null,"source":{"id":"https://openalex.org/S103225281","display_name":"NeuroImage","issn_l":"1053-8119","issn":["1053-8119","1095-9572"],"is_oa":true,"is_in_doaj":true,"is_indexed_in_scopus":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true},"sustainable_development_goals":[{"score":0.65,"display_name":"Gender equality","id":"https://metadata.un.org/sdg/5"}],"grants":[{"funder":"https://openalex.org/F4320321540","funder_display_name":"Ministry of Science and Technology of the People's Republic of China","award_id":null},{"funder":"https://openalex.org/F4320323230","funder_display_name":"Xidian University","award_id":"TZJH2024016"},{"funder":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China","award_id":"2022YFC3500603"}],"datasets":[],"versions":[],"referenced_works_count":82,"referenced_works":["https://openalex.org/W1529509939","https://openalex.org/W1547865271","https://openalex.org/W1567412268","https://openalex.org/W1695265315","https://openalex.org/W1971994650","https://openalex.org/W1977502547","https://openalex.org/W1978489779","https://openalex.org/W1981382840","https://openalex.org/W1984453610","https://openalex.org/W1985871295","https://openalex.org/W1997982013","https://openalex.org/W2005527520","https://openalex.org/W2006096283","https://openalex.org/W2009872283","https://openalex.org/W2018473894","https://openalex.org/W2027289999","https://openalex.org/W2032032832","https://openalex.org/W2049304885","https://openalex.org/W2053790692","https://openalex.org/W2055655674","https://openalex.org/W2060693962","https://openalex.org/W2062947528","https://openalex.org/W2071666535","https://openalex.org/W2072833030","https://openalex.org/W2083828032","https://openalex.org/W2084737128","https://openalex.org/W2089089460","https://openalex.org/W2103017472","https://openalex.org/W2109752884","https://openalex.org/W2110654827","https://openalex.org/W2124649657","https://openalex.org/W2127309075","https://openalex.org/W2136573752","https://openalex.org/W2148828979","https://openalex.org/W2156295541","https://openalex.org/W2160662805","https://openalex.org/W2165478810","https://openalex.org/W2172095686","https://openalex.org/W2177917702","https://openalex.org/W2258511068","https://openalex.org/W2313634937","https://openalex.org/W2345555088","https://openalex.org/W2402346616","https://openalex.org/W2407313014","https://openalex.org/W2508982726","https://openalex.org/W2554682324","https://openalex.org/W2559813826","https://openalex.org/W2753903181","https://openalex.org/W2788755901","https://openalex.org/W2796133564","https://openalex.org/W2796871073","https://openalex.org/W2805284222","https://openalex.org/W2895693082","https://openalex.org/W2899422702","https://openalex.org/W2913988157","https://openalex.org/W2914619606","https://openalex.org/W2951032685","https://openalex.org/W2953130519","https://openalex.org/W2970898057","https://openalex.org/W2972864586","https://openalex.org/W2977883299","https://openalex.org/W3023228745","https://openalex.org/W3036589033","https://openalex.org/W3043216964","https://openalex.org/W3165837403","https://openalex.org/W3173024175","https://openalex.org/W3177722730","https://openalex.org/W3199575537","https://openalex.org/W3200528712","https://openalex.org/W3208846400","https://openalex.org/W4210958358","https://openalex.org/W4236523229","https://openalex.org/W4245095371","https://openalex.org/W4280587578","https://openalex.org/W4302362454","https://openalex.org/W4308592535","https://openalex.org/W4319003751","https://openalex.org/W4323036511","https://openalex.org/W4384201322","https://openalex.org/W4391882932","https://openalex.org/W4395052015","https://openalex.org/W66443818"],"related_works":["https://openalex.org/W4401768695","https://openalex.org/W4391375266","https://openalex.org/W2931662336","https://openalex.org/W2765597752","https://openalex.org/W2748952813","https://openalex.org/W2405220830","https://openalex.org/W2348012590","https://openalex.org/W2077865380","https://openalex.org/W2020741738","https://openalex.org/W1541981780"],"abstract_inverted_index":{"The":[0,13],"neural":[1],"basis":[2],"of":[3,53,146,162],"sex-related":[4,28,151],"differences":[5,49,66,119,138,152],"in":[6,50,84,120,123,139,150,153],"processing":[7,154],"negative":[8,75,103,155],"emotions":[9],"remains":[10],"poorly":[11],"understood.":[12],"amygdala-related":[14],"fiber":[15],"pathways":[16,32],"serve":[17,96],"as":[18,97,133],"the":[19,26,54,58,85,92,144,147],"neuroanatomical":[20,99],"foundation":[21,100],"for":[22,101,173],"emotion":[23,104,164],"processing.":[24],"However,":[25],"precise":[27],"variations":[29],"within":[30],"these":[31],"remain":[33],"largely":[34],"elusive.":[35],"Using":[36],"diffusion":[37],"magnetic":[38],"resonance":[39],"imaging":[40,126],"data":[41],"from":[42],"418":[43],"healthy":[44],"individuals,":[45],"we":[46,114],"identified":[47],"sex":[48,118,137],"white-matter":[51],"microstructures":[52],"striato-amygdaloid-prefrontal":[55,148],"tracts,":[56],"particularly":[57],"amygdala":[59],"(Amy)-medial":[60],"prefrontal":[61],"cortex":[62],"(mPFC)":[63],"pathway.":[64],"These":[65,141],"were":[67],"associated":[68],"with":[69],"various":[70],"neurobiological":[71],"factors,":[72],"including":[73],"pain-related":[74],"emotions,":[76],"pain":[77],"sensitivity,":[78],"neurotransmitter":[79,111],"receptors,":[80],"and":[81,110,166,175],"gene":[82],"expressions":[83],"human":[86],"brain.":[87],"Our":[88],"findings":[89,142],"suggested":[90],"that":[91],"Amy-mPFC":[93],"pathway":[94,122],"may":[95,158],"a":[98,134],"sex-specific":[102,163],"processing,":[105],"driven":[106],"by":[107],"specific":[108],"genetic":[109],"profiles.":[112],"Notably,":[113],"also":[115],"found":[116],"similar":[117],"this":[121],"an":[124],"infant":[125],"dataset,":[127],"hinting":[128],"at":[129],"its":[130],"developmental":[131],"significance":[132],"precursor":[135],"to":[136],"adulthood.":[140],"underscore":[143],"importance":[145],"tracts":[149],"emotions.":[156],"This":[157],"enhance":[159],"our":[160],"understanding":[161],"regulation":[165,178],"potentially":[167],"inform":[168],"future":[169],"research":[170],"on":[171],"strategies":[172],"preventing":[174],"diagnosing":[176],"emotional":[177],"disorders":[179],"across":[180],"sexes.":[181]},"abstract_inverted_index_v3":null,"cited_by_api_url":"https://api.openalex.org/works?filter=cites:W4404522100","counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2025-05-06T03:16:53.399184","created_date":"2024-11-20"}