乐胖代购免代理版

{"id":"https://openalex.org/W4400428245","doi":"https://doi.org/10.1007/s12021-024-09673-7","title":"Generative Modelling of Cortical Receptor Distributions from Cytoarchitectonic Images in the Macaque Brain","display_name":"Generative Modelling of Cortical Receptor Distributions from Cytoarchitectonic Images in the Macaque Brain","publication_year":2024,"publication_date":"2024-07-08","ids":{"openalex":"https://openalex.org/W4400428245","doi":"https://doi.org/10.1007/s12021-024-09673-7","pmid":"https://pubmed.ncbi.nlm.nih.gov/38976151"},"language":"en","primary_location":{"is_oa":true,"landing_page_url":"https://doi.org/10.1007/s12021-024-09673-7","pdf_url":"https://link.springer.com/content/pdf/10.1007/s12021-024-09673-7.pdf","source":{"id":"https://openalex.org/S3444786","display_name":"Neuroinformatics","issn_l":"1539-2791","issn":["1539-2791","1559-0089"],"is_oa":false,"is_in_doaj":false,"is_indexed_in_scopus":true,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319965","https://openalex.org/P4310319900"],"host_organization_lineage_names":["Springer Nature","Springer Science+Business Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true},"type":"article","type_crossref":"journal-article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://link.springer.com/content/pdf/10.1007/s12021-024-09673-7.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5059902971","display_name":"Ahmed Nebli","orcid":"https://orcid.org/0000-0003-4565-4502"},"institutions":[{"id":"https://openalex.org/I171892758","display_name":"Forschungszentrum J\u00fclich","ror":"https://ror.org/02nv7yv05","country_code":"DE","type":"funder","lineage":["https://openalex.org/I1305996414","https://openalex.org/I171892758"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Ahmed Nebli","raw_affiliation_strings":["Institute of Neuroscience and Medicine (INM-1), Research Centre J\u00fclich, J\u00fclich, Germany"],"affiliations":[{"raw_affiliation_string":"Institute of Neuroscience and Medicine (INM-1), Research Centre J\u00fclich, J\u00fclich, Germany","institution_ids":["https://openalex.org/I171892758"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016982898","display_name":"Christian Schiffer","orcid":"https://orcid.org/0000-0002-2544-843X"},"institutions":[{"id":"https://openalex.org/I171892758","display_name":"Forschungszentrum J\u00fclich","ror":"https://ror.org/02nv7yv05","country_code":"DE","type":"funder","lineage":["https://openalex.org/I1305996414","https://openalex.org/I171892758"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Christian Schiffer","raw_affiliation_strings":["Institute of Neuroscience and Medicine (INM-1), Research Centre J\u00fclich, J\u00fclich, Germany"],"affiliations":[{"raw_affiliation_string":"Institute of Neuroscience and Medicine (INM-1), Research Centre J\u00fclich, J\u00fclich, Germany","institution_ids":["https://openalex.org/I171892758"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021900492","display_name":"Meiqi Niu","orcid":"https://orcid.org/0000-0001-7937-5814"},"institutions":[{"id":"https://openalex.org/I171892758","display_name":"Forschungszentrum J\u00fclich","ror":"https://ror.org/02nv7yv05","country_code":"DE","type":"funder","lineage":["https://openalex.org/I1305996414","https://openalex.org/I171892758"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Meiqi Niu","raw_affiliation_strings":["Institute of Neuroscience and Medicine (INM-1), Research Centre J\u00fclich, J\u00fclich, Germany"],"affiliations":[{"raw_affiliation_string":"Institute of Neuroscience and Medicine (INM-1), Research Centre J\u00fclich, J\u00fclich, Germany","institution_ids":["https://openalex.org/I171892758"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003889607","display_name":"Nicola Palomero\u2010Gallagher","orcid":"https://orcid.org/0000-0003-4463-8578"},"institutions":[{"id":"https://openalex.org/I171892758","display_name":"Forschungszentrum J\u00fclich","ror":"https://ror.org/02nv7yv05","country_code":"DE","type":"funder","lineage":["https://openalex.org/I1305996414","https://openalex.org/I171892758"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Nicola Palomero-Gallagher","raw_affiliation_strings":["Institute of Neuroscience and Medicine (INM-1), Research Centre J\u00fclich, J\u00fclich, Germany"],"affiliations":[{"raw_affiliation_string":"Institute of Neuroscience and Medicine (INM-1), Research Centre J\u00fclich, J\u00fclich, Germany","institution_ids":["https://openalex.org/I171892758"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009333521","display_name":"Katrin Amunts","orcid":"https://orcid.org/0000-0001-5828-0867"},"institutions":[{"id":"https://openalex.org/I171892758","display_name":"Forschungszentrum J\u00fclich","ror":"https://ror.org/02nv7yv05","country_code":"DE","type":"funder","lineage":["https://openalex.org/I1305996414","https://openalex.org/I171892758"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Katrin Amunts","raw_affiliation_strings":["Institute of Neuroscience and Medicine (INM-1), Research Centre J\u00fclich, J\u00fclich, Germany"],"affiliations":[{"raw_affiliation_string":"Institute of Neuroscience and Medicine (INM-1), Research Centre J\u00fclich, J\u00fclich, Germany","institution_ids":["https://openalex.org/I171892758"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014859866","display_name":"Timo Dickscheid","orcid":"https://orcid.org/0000-0002-9051-3701"},"institutions":[{"id":"https://openalex.org/I171892758","display_name":"Forschungszentrum J\u00fclich","ror":"https://ror.org/02nv7yv05","country_code":"DE","type":"funder","lineage":["https://openalex.org/I1305996414","https://openalex.org/I171892758"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Timo Dickscheid","raw_affiliation_strings":["Institute of Neuroscience and Medicine (INM-1), Research Centre J\u00fclich, J\u00fclich, Germany"],"affiliations":[{"raw_affiliation_string":"Institute of Neuroscience and Medicine (INM-1), Research Centre J\u00fclich, J\u00fclich, Germany","institution_ids":["https://openalex.org/I171892758"]}]}],"institution_assertions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5059902971"],"corresponding_institution_ids":["https://openalex.org/I171892758"],"apc_list":{"value":3190,"currency":"EUR","value_usd":4190},"apc_paid":{"value":3190,"currency":"EUR","value_usd":4190},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":0,"max":77},"biblio":{"volume":"22","issue":"3","first_page":"389","last_page":"402"},"is_retracted":false,"is_paratext":false,"primary_topic":{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9991,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9991,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9982,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":0.9925,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neurotransmitter-receptor","display_name":"Neurotransmitter receptor","score":0.59855604}],"concepts":[{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6035588},{"id":"https://openalex.org/C156927020","wikidata":"https://www.wikidata.org/wiki/Q1187783","display_name":"Neurotransmitter receptor","level":3,"score":0.59855604},{"id":"https://openalex.org/C2779345533","wikidata":"https://www.wikidata.org/wiki/Q75785","display_name":"Visual cortex","level":2,"score":0.5095175},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4618783},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4548304},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.44646126},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4307141},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.423465},{"id":"https://openalex.org/C2778950215","wikidata":"https://www.wikidata.org/wiki/Q177601","display_name":"Macaque","level":2,"score":0.41728634},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.32194096},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008253","descriptor_name":"Macaca mulatta","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009044","descriptor_name":"Motor Cortex","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018092","descriptor_name":"Receptors, Kainic Acid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017981","descriptor_name":"Receptors, Neurotransmitter","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":2,"locations":[{"is_oa":true,"landing_page_url":"https://doi.org/10.1007/s12021-024-09673-7","pdf_url":"https://link.springer.com/content/pdf/10.1007/s12021-024-09673-7.pdf","source":{"id":"https://openalex.org/S3444786","display_name":"Neuroinformatics","issn_l":"1539-2791","issn":["1539-2791","1559-0089"],"is_oa":false,"is_in_doaj":false,"is_indexed_in_scopus":true,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319965","https://openalex.org/P4310319900"],"host_organization_lineage_names":["Springer Nature","Springer Science+Business Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true},{"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38976151","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_indexed_in_scopus":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":["National Institutes of Health"],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false}],"best_oa_location":{"is_oa":true,"landing_page_url":"https://doi.org/10.1007/s12021-024-09673-7","pdf_url":"https://link.springer.com/content/pdf/10.1007/s12021-024-09673-7.pdf","source":{"id":"https://openalex.org/S3444786","display_name":"Neuroinformatics","issn_l":"1539-2791","issn":["1539-2791","1559-0089"],"is_oa":false,"is_in_doaj":false,"is_indexed_in_scopus":true,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319965","https://openalex.org/P4310319900"],"host_organization_lineage_names":["Springer Nature","Springer Science+Business Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true},"sustainable_development_goals":[],"grants":[],"datasets":[],"versions":[],"referenced_works_count":34,"referenced_works":["https://openalex.org/W1548529611","https://openalex.org/W180394468","https://openalex.org/W1824317634","https://openalex.org/W1901129140","https://openalex.org/W1967871299","https://openalex.org/W1971687696","https://openalex.org/W1973719379","https://openalex.org/W2024251150","https://openalex.org/W2027782937","https://openalex.org/W2034826897","https://openalex.org/W204906517","https://openalex.org/W2055494836","https://openalex.org/W2064076387","https://openalex.org/W2183341477","https://openalex.org/W2189464011","https://openalex.org/W2263104832","https://openalex.org/W2345435404","https://openalex.org/W2475287302","https://openalex.org/W2571908433","https://openalex.org/W2749595928","https://openalex.org/W2755647903","https://openalex.org/W2789382909","https://openalex.org/W2883183514","https://openalex.org/W3003951577","https://openalex.org/W3009905891","https://openalex.org/W3009961050","https://openalex.org/W3045803172","https://openalex.org/W3092747519","https://openalex.org/W3100588730","https://openalex.org/W3126915734","https://openalex.org/W4200197261","https://openalex.org/W4296618923","https://openalex.org/W4309300416","https://openalex.org/W4381189461"],"related_works":["https://openalex.org/W4241863880","https://openalex.org/W3144054911","https://openalex.org/W2801853238","https://openalex.org/W2607084827","https://openalex.org/W2357501381","https://openalex.org/W2305557535","https://openalex.org/W2186586247","https://openalex.org/W2027494808","https://openalex.org/W2001963156","https://openalex.org/W1162584952"],"abstract_inverted_index":{"Abstract":[0],"Neurotransmitter":[1],"receptor":[2,17,25,75,111,117,155,177],"densities":[3,178],"are":[4],"relevant":[5],"for":[6,77,118],"understanding":[7],"the":[8,46,66,84,105,109,115,121,161,196],"molecular":[9],"architecture":[10],"of":[11,27,62,86,108,112,136,165,198],"brain":[12,28,58,209],"regions.":[13],"Quantitative":[14],"in":[15,74,120,207],"vitro":[16],"autoradiography,":[18],"has":[19],"been":[20],"introduced":[21],"to":[22,41,71,103,175,203],"map":[23],"neurotransmitter":[24,89],"distributions":[26,91,107],"areas.":[29],"However,":[30],"it":[31,39],"is":[32,142],"very":[33],"time":[34],"and":[35,52,114,127,154,170,191],"cost-intensive,":[36],"which":[37],"makes":[38],"challenging":[40],"obtain":[42],"whole-brain":[43,80],"distributions.":[44],"At":[45],"same":[47],"time,":[48],"high-throughput":[49],"light":[50,133],"microscopy":[51],"3D":[53],"reconstructions":[54],"have":[55],"enabled":[56],"high-resolution":[57],"maps":[59],"capturing":[60],"measures":[61],"cell":[63],"density":[64,90,106],"across":[65],"whole":[67],"human":[68],"brain.":[69],"Aiming":[70],"bridge":[72],"gaps":[73,206],"measurements":[76],"building":[78],"detailed":[79],"atlases,":[81],"we":[82,96],"study":[83],"feasibility":[85,197],"predicting":[87],"realistic":[88],"from":[92,147,179],"cell-body":[93,137,153,180],"stainings.":[94],"Specifically,":[95],"utilize":[97],"conditional":[98],"Generative":[99],"Adversarial":[100],"Networks":[101],"(cGANs)":[102],"predict":[104,176],"M2":[110],"acetylcholine":[113],"kainate":[116],"glutamate":[119],"macaque":[122],"monkey\u2019s":[123],"primary":[124],"visual":[125],"(V1)":[126],"motor":[128],"cortex":[129],"(M1),":[130],"based":[131],"on":[132,144],"microscopic":[134],"scans":[135],"stained":[138,181],"sections.":[139],"Our":[140,193],"model":[141],"trained":[143],"corresponding":[145],"patches":[146],"aligned":[148],"consecutive":[149],"sections":[150,182],"that":[151],"display":[152],"distributions,":[156],"ensuring":[157],"a":[158],"mapping":[159],"between":[160],"two":[162],"modalities.":[163],"Evaluations":[164],"our":[166],"cGANs,":[167],"both":[168],"qualitative":[169],"quantitative,":[171],"show":[172],"their":[173],"capability":[174],"while":[183],"maintaining":[184],"cortical":[185],"features":[186],"such":[187],"as":[188],"laminar":[189],"thickness":[190],"curvature.":[192],"work":[194],"underscores":[195],"cross-modality":[199],"image":[200],"translation":[201],"problems":[202],"address":[204],"data":[205],"multi-modal":[208],"atlases.":[210]},"abstract_inverted_index_v3":null,"cited_by_api_url":"https://api.openalex.org/works?filter=cites:W4400428245","counts_by_year":[],"updated_date":"2025-04-16T18:35:54.382577","created_date":"2024-07-09"}