乐胖代购免代理版

{"id":"https://openalex.org/W167494913","doi":"https://doi.org/10.1007/11946465_23","title":"Integrating Clinical and Genomic Information Through the PrognoChip Mediator","display_name":"Integrating Clinical and Genomic Information Through the PrognoChip Mediator","publication_year":2006,"publication_date":"2006-01-01","ids":{"openalex":"https://openalex.org/W167494913","doi":"https://doi.org/10.1007/11946465_23","mag":"167494913"},"language":"en","primary_location":{"is_oa":false,"landing_page_url":"https://doi.org/10.1007/11946465_23","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319965","https://openalex.org/P4310319900"],"host_organization_lineage_names":["Springer Nature","Springer Science+Business Media"],"type":"book series"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false},"type":"book-chapter","type_crossref":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":"http://www.ics.forth.gr/isl/publications/paperlink/Progn_Mediator_ISBMDA06_pv.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039919297","display_name":"Anastasia Analyti","orcid":"https://orcid.org/0000-0002-6563-1896"},"institutions":[{"id":"https://openalex.org/I4210121775","display_name":"FORTH Institute of Computer Science","ror":"https://ror.org/02tf48g55","country_code":"GR","type":"facility","lineage":["https://openalex.org/I4210121775","https://openalex.org/I8901234"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Anastasia Analyti","raw_affiliation_strings":["Information Systems Lab, Institute of Computer Science, FORTH-ICS, Greece"],"affiliations":[{"raw_affiliation_string":"Information Systems Lab, Institute of Computer Science, FORTH-ICS, Greece","institution_ids":["https://openalex.org/I4210121775"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070664655","display_name":"Haridimos Kondylakis","orcid":"https://orcid.org/0000-0002-9917-4486"},"institutions":[{"id":"https://openalex.org/I4210121775","display_name":"FORTH Institute of Computer Science","ror":"https://ror.org/02tf48g55","country_code":"GR","type":"facility","lineage":["https://openalex.org/I4210121775","https://openalex.org/I8901234"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Haridimos Kondylakis","raw_affiliation_strings":["Information Systems Lab, Institute of Computer Science, FORTH-ICS, Greece"],"affiliations":[{"raw_affiliation_string":"Information Systems Lab, Institute of Computer Science, FORTH-ICS, Greece","institution_ids":["https://openalex.org/I4210121775"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020550402","display_name":"Dimitris Manakanatas","orcid":null},"institutions":[{"id":"https://openalex.org/I4210121775","display_name":"FORTH Institute of Computer Science","ror":"https://ror.org/02tf48g55","country_code":"GR","type":"facility","lineage":["https://openalex.org/I4210121775","https://openalex.org/I8901234"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Dimitris Manakanatas","raw_affiliation_strings":["Information Systems Lab, Institute of Computer Science, FORTH-ICS, Greece"],"affiliations":[{"raw_affiliation_string":"Information Systems Lab, Institute of Computer Science, FORTH-ICS, Greece","institution_ids":["https://openalex.org/I4210121775"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056763638","display_name":"Manos Kalaitzakis","orcid":null},"institutions":[{"id":"https://openalex.org/I4210121775","display_name":"FORTH Institute of Computer Science","ror":"https://ror.org/02tf48g55","country_code":"GR","type":"facility","lineage":["https://openalex.org/I4210121775","https://openalex.org/I8901234"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Manos Kalaitzakis","raw_affiliation_strings":["Information Systems Lab, Institute of Computer Science, FORTH-ICS, Greece"],"affiliations":[{"raw_affiliation_string":"Information Systems Lab, Institute of Computer Science, FORTH-ICS, Greece","institution_ids":["https://openalex.org/I4210121775"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004081767","display_name":"Dimitris Plexousakis","orcid":"https://orcid.org/0000-0002-0863-8266"},"institutions":[{"id":"https://openalex.org/I4210121775","display_name":"FORTH Institute of Computer Science","ror":"https://ror.org/02tf48g55","country_code":"GR","type":"facility","lineage":["https://openalex.org/I4210121775","https://openalex.org/I8901234"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Dimitris Plexousakis","raw_affiliation_strings":["Information Systems Lab, Institute of Computer Science, FORTH-ICS, Greece"],"affiliations":[{"raw_affiliation_string":"Information Systems Lab, Institute of Computer Science, FORTH-ICS, Greece","institution_ids":["https://openalex.org/I4210121775"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5084193547","display_name":"George Potamias","orcid":"https://orcid.org/0000-0001-8129-4191"},"institutions":[{"id":"https://openalex.org/I4210121775","display_name":"FORTH Institute of Computer Science","ror":"https://ror.org/02tf48g55","country_code":"GR","type":"facility","lineage":["https://openalex.org/I4210121775","https://openalex.org/I8901234"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"George Potamias","raw_affiliation_strings":["Biomedical Informatics Lab, Institute of Computer Science, FORTH-ICS, Greece"],"affiliations":[{"raw_affiliation_string":"Biomedical Informatics Lab, Institute of Computer Science, FORTH-ICS, Greece","institution_ids":["https://openalex.org/I4210121775"]}]}],"institution_assertions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5000,"currency":"EUR","value_usd":5392,"provenance":"doaj"},"apc_paid":null,"fwci":3.698,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.745063,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":75,"max":76},"biblio":{"volume":null,"issue":null,"first_page":"250","last_page":"261"},"is_retracted":false,"is_paratext":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Microarray Data Analysis and Gene Expression Profiling","score":0.9997,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Microarray Data Analysis and Gene Expression Profiling","score":0.9997,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Analysis of Gene Interaction Networks","score":0.9942,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11710","display_name":"Biomedical Ontologies and Text Mining","score":0.9916,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/genomic-data-integration","display_name":"Genomic Data Integration","score":0.567014},{"id":"https://openalex.org/keywords/interface","display_name":"Interface (matter)","score":0.5075878},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.50738},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.5056579},{"id":"https://openalex.org/keywords/health-informatics-tools","display_name":"Health informatics tools","score":0.47563887}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.77041316},{"id":"https://openalex.org/C191630685","wikidata":"https://www.wikidata.org/wiki/Q4027615","display_name":"Informatics","level":2,"score":0.5271577},{"id":"https://openalex.org/C23123220","wikidata":"https://www.wikidata.org/wiki/Q816826","display_name":"Information retrieval","level":1,"score":0.52195853},{"id":"https://openalex.org/C145642194","wikidata":"https://www.wikidata.org/wiki/Q870895","display_name":"Health informatics","level":3,"score":0.5162425},{"id":"https://openalex.org/C113843644","wikidata":"https://www.wikidata.org/wiki/Q901882","display_name":"Interface (matter)","level":4,"score":0.5075878},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.5056579},{"id":"https://openalex.org/C89505385","wikidata":"https://www.wikidata.org/wiki/Q47146","display_name":"User interface","level":2,"score":0.49308845},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.49146044},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.4817605},{"id":"https://openalex.org/C167785021","wikidata":"https://www.wikidata.org/wiki/Q5691083","display_name":"Health informatics tools","level":3,"score":0.47563887},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.36488497},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3643344},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.14734143},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.123101145},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.10589805},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09551838},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0},{"id":"https://openalex.org/C157915830","wikidata":"https://www.wikidata.org/wiki/Q2928001","display_name":"Bubble","level":2,"score":0.0},{"id":"https://openalex.org/C129307140","wikidata":"https://www.wikidata.org/wiki/Q6795880","display_name":"Maximum bubble pressure method","level":3,"score":0.0},{"id":"https://openalex.org/C173608175","wikidata":"https://www.wikidata.org/wiki/Q232661","display_name":"Parallel computing","level":1,"score":0.0},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C138816342","wikidata":"https://www.wikidata.org/wiki/Q189603","display_name":"Public health","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"is_oa":false,"landing_page_url":"https://doi.org/10.1007/11946465_23","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319965","https://openalex.org/P4310319900"],"host_organization_lineage_names":["Springer Nature","Springer Science+Business Media"],"type":"book series"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false},{"is_oa":true,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.144.9219","pdf_url":"http://www.ics.forth.gr/isl/publications/paperlink/Progn_Mediator_ISBMDA06_pv.pdf","source":{"id":"https://openalex.org/S4306400349","display_name":"CiteSeer X (The Pennsylvania State University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I130769515","host_organization_name":"Pennsylvania State University","host_organization_lineage":["https://openalex.org/I130769515"],"host_organization_lineage_names":["Pennsylvania State University"],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false}],"best_oa_location":{"is_oa":true,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.144.9219","pdf_url":"http://www.ics.forth.gr/isl/publications/paperlink/Progn_Mediator_ISBMDA06_pv.pdf","source":{"id":"https://openalex.org/S4306400349","display_name":"CiteSeer X (The Pennsylvania State University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I130769515","host_organization_name":"Pennsylvania State University","host_organization_lineage":["https://openalex.org/I130769515"],"host_organization_lineage_names":["Pennsylvania State University"],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.47}],"grants":[],"datasets":[],"versions":[],"referenced_works_count":10,"referenced_works":["https://openalex.org/W1576955607","https://openalex.org/W2020245432","https://openalex.org/W2023851271","https://openalex.org/W2057613070","https://openalex.org/W2107519221","https://openalex.org/W2135557996","https://openalex.org/W2156246479","https://openalex.org/W2160948978","https://openalex.org/W2167340209","https://openalex.org/W2501213684"],"related_works":["https://openalex.org/W4323056170","https://openalex.org/W4302329558","https://openalex.org/W2993510912","https://openalex.org/W2914293784","https://openalex.org/W2401910071","https://openalex.org/W2397677514","https://openalex.org/W2229314870","https://openalex.org/W2126732312","https://openalex.org/W1971571384","https://openalex.org/W1495820741"],"abstract_inverted_index":{"The":[0,85],"ultimate":[1],"goal":[2],"of":[3,12,27,31,46,65,76,98,125,140],"the":[4,10,28,32,36,44,54,62,66,74,77,93,99,132,148,158,163],"biomedical":[5,86],"informatics":[6],"project":[7],"PrognoChip":[8,67],"is":[9,83,102,130],"identification":[11],"classification":[13],"and":[14,79,119],"prognosis":[15],"molecular":[16],"markers":[17],"for":[18,155,167],"breast":[19],"cancer.":[20],"This":[21,101],"requires":[22],"not":[23],"only":[24],"an":[25,137],"understanding":[26],"genetic":[29],"basis":[30],"disease,":[33],"based":[34,122],"on":[35,123],"patient's":[37],"tumor":[38],"gene":[39,116],"expression":[40,117],"profiles":[41,118],"but":[42],"also":[43],"correlation":[45],"this":[47,58],"data":[48],"with":[49,113],"knowledge":[50],"normally":[51],"processed":[52],"in":[53],"clinical":[55,78],"setting.":[56],"In":[57],"paper,":[59],"we":[60],"present":[61],"Mediator":[63,133],"component":[64],"Integrated":[68],"Clinico-Genomics":[69],"Environment":[70],"(ICGE),":[71],"through":[72,92],"which":[73,143],"integration":[75],"genomic":[80],"information":[81],"subsystems":[82],"achieved.":[84],"investigator":[87],"can":[88],"form":[89],"clinico-genomic":[90],"queries":[91],"web-based":[94],"graphical":[95],"user":[96,159],"interface":[97],"Mediator.":[100],"split":[103],"into":[104,136],"several":[105],"query":[106,129],"forms,":[107],"allowing":[108],"cancerous":[109],"sample":[110],"selection":[111],"(along":[112],"their":[114],"associated":[115],"patient":[120],"characteristics),":[121],"criteria":[124],"interest.":[126],"After":[127],"a":[128],"formed,":[131],"translates":[134],"it":[135],"equivalent":[138],"set":[139],"local":[141],"subqueries,":[142],"are":[144,153],"executed":[145],"directly":[146],"against":[147],"constituent":[149],"databases.":[150],"Then,":[151],"results":[152],"combined":[154],"presentation":[156],"to":[157,162],"and/or":[160],"transmission":[161],"Data":[164],"Mining":[165],"tools":[166],"analysis.":[168]},"cited_by_api_url":"https://api.openalex.org/works?filter=cites:W167494913","counts_by_year":[],"updated_date":"2024-11-30T22:36:25.916802","created_date":"2016-06-24"}