{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,1,21]],"date-time":"2025-01-21T05:22:40Z","timestamp":1737436960435,"version":"3.33.0"},"reference-count":125,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"the National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["52272053","52075527","52102055"],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"the National Key R&D Program of China","award":["2022YFA1203100","2022YFB3706602","2021YFB3701801"]},{"name":"Ningbo Key Scientific and Technological Project","award":["2021Z120","2021Z115","2022Z084","2022Z191"]},{"name":"the Yongjiang Talent Introduction Programme of Ningbo","award":["2021A-037-C","2021A-108-G"]},{"name":"the Youth Fund of Chinese Academy of Sciences","award":["JCPYJ-22030"]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"crossref","award":["2020M681965","2022M713243)"],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"crossref"}]},{"name":"CAS Youth Innovation Promotion Association","award":["2020301"]},{"name":"Science and Technology Major Project of Ningbo","award":["2021ZDYF020196","2021ZDYF020198"]},{"name":"the Project of Chinese Academy of Science","award":["XDA22020602","ZDKYYQ2020001"]},{"DOI":"10.13039\/501100017522","name":"Ningbo 3315 Innovation Team","doi-asserted-by":"crossref","award":["2019A-18-C"],"id":[{"id":"10.13039\/501100017522","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"Recent advancements in polymer-assisted layer-by-layer (LbL) fabrication have revolutionized the development of wearable sensors for health monitoring. LbL self-assembly has emerged as a powerful and versatile technique for creating conformal, flexible, and multi-functional films on various substrates, making it particularly suitable for fabricating wearable sensors. The incorporation of polymers, both natural and synthetic, has played a crucial role in enhancing the performance, stability, and biocompatibility of these sensors. This review provides a comprehensive overview of the principles of LbL self-assembly, the role of polymers in sensor fabrication, and the various types of LbL-fabricated wearable sensors for physical, chemical, and biological sensing. The applications of these sensors in continuous health monitoring, disease diagnosis, and management are discussed in detail, highlighting their potential to revolutionize personalized healthcare. Despite significant progress, challenges related to long-term stability, biocompatibility, data acquisition, and large-scale manufacturing are still to be addressed, providing insights into future research directions. With continued advancements in polymer-assisted LbL fabrication and related fields, wearable sensors are poised to improve the quality of life for individuals worldwide.<\/jats:p>","DOI":"10.3390\/s24092903","type":"journal-article","created":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T12:59:39Z","timestamp":1714568379000},"page":"2903","source":"Crossref","is-referenced-by-count":4,"title":["Advancements in Polymer-Assisted Layer-by-Layer Fabrication of Wearable Sensors for Health Monitoring"],"prefix":"10.3390","volume":"24","author":[{"given":"Meiqing","family":"Jin","sequence":"first","affiliation":[{"name":"College of Materials and Environmental Engineering, Hangzhou Dianzi University, Hangzhou 310018, China"}]},{"given":"Peizheng","family":"Shi","sequence":"additional","affiliation":[{"name":"Qianwan Institute, Ningbo Institute of Materials Technology and Engineering (NIMTE), Chinese Academy of Sciences, Ningbo 315201, China"},{"name":"Key Laboratory of Marine Materials and Related Technologies, Zhejiang Key Laboratory of Marine Materials and Protective Technologies, Ningbo Institute of Materials Technology and Engineering (NIMTE), Chinese Academy of Sciences, Ningbo 315201, China"},{"name":"University of Chinese Academy of Sciences, 19 A Yuquan Rd., Shijingshan District, Beijing 100049, China"}]},{"given":"Zhuang","family":"Sun","sequence":"additional","affiliation":[{"name":"Qianwan Institute, Ningbo Institute of Materials Technology and Engineering (NIMTE), Chinese Academy of Sciences, Ningbo 315201, China"},{"name":"Key Laboratory of Marine Materials and Related Technologies, Zhejiang Key Laboratory of Marine Materials and Protective Technologies, Ningbo Institute of Materials Technology and Engineering (NIMTE), Chinese Academy of Sciences, Ningbo 315201, China"},{"name":"University of Chinese Academy of Sciences, 19 A Yuquan Rd., Shijingshan District, Beijing 100049, China"}]},{"given":"Ningbin","family":"Zhao","sequence":"additional","affiliation":[{"name":"Qianwan Institute, Ningbo Institute of Materials Technology and Engineering (NIMTE), Chinese Academy of Sciences, Ningbo 315201, China"},{"name":"Key Laboratory of Marine Materials and Related Technologies, Zhejiang Key Laboratory of Marine Materials and Protective Technologies, Ningbo Institute of Materials Technology and Engineering (NIMTE), Chinese Academy of Sciences, Ningbo 315201, China"},{"name":"University of Chinese Academy of Sciences, 19 A Yuquan Rd., Shijingshan District, Beijing 100049, China"}]},{"given":"Mingjiao","family":"Shi","sequence":"additional","affiliation":[{"name":"Qianwan Institute, Ningbo Institute of Materials Technology and Engineering (NIMTE), Chinese Academy of Sciences, Ningbo 315201, China"},{"name":"Key Laboratory of Marine Materials and Related Technologies, Zhejiang Key Laboratory of Marine Materials and Protective Technologies, Ningbo Institute of Materials Technology and Engineering (NIMTE), Chinese Academy of Sciences, Ningbo 315201, China"},{"name":"University of Chinese Academy of Sciences, 19 A Yuquan Rd., Shijingshan District, Beijing 100049, China"}]},{"given":"Mengfan","family":"Wu","sequence":"additional","affiliation":[{"name":"Qianwan Institute, Ningbo Institute of Materials Technology and Engineering (NIMTE), Chinese Academy of Sciences, Ningbo 315201, China"},{"name":"Key Laboratory of Marine Materials and Related Technologies, Zhejiang Key Laboratory of Marine Materials and Protective Technologies, Ningbo Institute of Materials Technology and Engineering (NIMTE), Chinese Academy of Sciences, Ningbo 315201, China"},{"name":"University of Chinese Academy of Sciences, 19 A Yuquan Rd., Shijingshan District, Beijing 100049, China"}]},{"given":"Chen","family":"Ye","sequence":"additional","affiliation":[{"name":"Qianwan Institute, Ningbo Institute of Materials Technology and Engineering (NIMTE), Chinese Academy of Sciences, Ningbo 315201, China"},{"name":"Key Laboratory of Marine Materials and Related Technologies, Zhejiang Key Laboratory of Marine Materials and Protective Technologies, Ningbo Institute of Materials Technology and Engineering (NIMTE), Chinese Academy of Sciences, Ningbo 315201, China"},{"name":"University of Chinese Academy of Sciences, 19 A Yuquan Rd., Shijingshan District, Beijing 100049, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7090-9610","authenticated-orcid":false,"given":"Cheng-Te","family":"Lin","sequence":"additional","affiliation":[{"name":"Qianwan Institute, Ningbo Institute of Materials Technology and Engineering (NIMTE), Chinese Academy of Sciences, Ningbo 315201, China"},{"name":"Key Laboratory of Marine Materials and Related Technologies, Zhejiang Key Laboratory of Marine Materials and Protective Technologies, Ningbo Institute of Materials Technology and Engineering (NIMTE), Chinese Academy of Sciences, Ningbo 315201, China"},{"name":"University of Chinese Academy of Sciences, 19 A Yuquan Rd., Shijingshan District, Beijing 100049, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5957-7790","authenticated-orcid":false,"given":"Li","family":"Fu","sequence":"additional","affiliation":[{"name":"College of Materials and Environmental Engineering, Hangzhou Dianzi University, Hangzhou 310018, China"}]}],"member":"1968","published-online":{"date-parts":[[2024,5,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"112105","DOI":"10.1016\/j.sna.2020.112105","article-title":"Progress and Challenges in Fabrication of Wearable Sensors for Health Monitoring","volume":"312","author":"Nasiri","year":"2020","journal-title":"Sens. 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