{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T14:49:59Z","timestamp":1740149399262,"version":"3.37.3"},"reference-count":39,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2020,6,25]],"date-time":"2020-06-25T00:00:00Z","timestamp":1593043200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2017YFB1300300"],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014717","name":"National Outstanding Youth Science Fund Project of National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81925020"],"id":[{"id":"10.13039\/100014717","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["61976152"],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Young Elite Scientist Sponsorship Program by CAST","award":["2018QNRC001"]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"Brain\u2013computer interfaces (BCI) have witnessed a rapid development in recent years. However, the active BCI paradigm is still underdeveloped with a lack of variety. It is imperative to adapt more voluntary mental activities for the active BCI control, which can induce separable electroencephalography (EEG) features. This study aims to demonstrate the brain function of timing prediction, i.e., the expectation of upcoming time intervals, is accessible for BCIs. Eighteen subjects were selected for this study. They were trained to have a precise idea of two sub-second time intervals, i.e., 400 ms and 600 ms, and were asked to measure a time interval of either 400 ms or 600 ms in mind after a cue onset. The EEG features induced by timing prediction were analyzed and classified using the combined discriminative canonical pattern matching and common spatial pattern. It was found that the ERPs in low-frequency (0~4 Hz) and energy in high-frequency (20~60 Hz) were separable for distinct timing predictions. The accuracy reached the highest of 93.75% with an average of 76.45% for the classification of 400 vs. 600 ms timing. This study first demonstrates that the cognitive EEG features induced by timing prediction are detectable and separable, which is feasible to be used in active BCIs controls and can broaden the category of BCIs.<\/jats:p>","DOI":"10.3390\/s20123588","type":"journal-article","created":{"date-parts":[[2020,6,25]],"date-time":"2020-06-25T14:36:54Z","timestamp":1593095814000},"page":"3588","source":"Crossref","is-referenced-by-count":12,"title":["Separable EEG Features Induced by Timing Prediction for Active Brain-Computer Interfaces"],"prefix":"10.3390","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1135-6518","authenticated-orcid":false,"given":"Jiayuan","family":"Meng","sequence":"first","affiliation":[{"name":"College of Precision Instruments and Optoelectronics Engineering, Tianjin University, Tianjin 300000, China"}]},{"given":"Minpeng","family":"Xu","sequence":"additional","affiliation":[{"name":"College of Precision Instruments and Optoelectronics Engineering, Tianjin University, Tianjin 300000, China"},{"name":"Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin 300000, China"}]},{"given":"Kun","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Precision Instruments and Optoelectronics Engineering, Tianjin University, Tianjin 300000, China"}]},{"given":"Qiangfan","family":"Meng","sequence":"additional","affiliation":[{"name":"Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin 300000, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6912-1738","authenticated-orcid":false,"given":"Jin","family":"Han","sequence":"additional","affiliation":[{"name":"College of Precision Instruments and Optoelectronics Engineering, Tianjin University, Tianjin 300000, China"}]},{"given":"Xiaolin","family":"Xiao","sequence":"additional","affiliation":[{"name":"College of Precision Instruments and Optoelectronics Engineering, Tianjin University, Tianjin 300000, China"}]},{"given":"Shuang","family":"Liu","sequence":"additional","affiliation":[{"name":"Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin 300000, China"}]},{"given":"Dong","family":"Ming","sequence":"additional","affiliation":[{"name":"College of Precision Instruments and Optoelectronics Engineering, Tianjin University, Tianjin 300000, China"},{"name":"Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin 300000, China"}]}],"member":"1968","published-online":{"date-parts":[[2020,6,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1016\/j.tins.2006.07.004","article-title":"Brain\u2013machine interfaces: Past, present and future","volume":"29","author":"Lebedev","year":"2006","journal-title":"Trends Neurosci."},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Wolpaw, J., and Wolpaw, E.W. 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