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{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T22:00:17Z","timestamp":1740175217361,"version":"3.37.3"},"reference-count":37,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T00:00:00Z","timestamp":1648684800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"European Union Horizon 2020 research and innovation program","award":["721766"]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Imaging"],"abstract":"Surgical excision is the golden standard for treatment of intestinal tumors. In this surgical procedure, inadequate perfusion of the anastomosis can lead to postoperative complications, such as anastomotic leakages. Imaging photoplethysmography (iPPG) can potentially provide objective and real-time feedback of the perfusion status of tissues. This feasibility study aims to evaluate an iPPG acquisition system during intestinal surgeries to detect the perfusion levels of the microvasculature tissue bed in different perfusion conditions. This feasibility study assesses three patients that underwent resection of a portion of the small intestine. Data was acquired from fully perfused, non-perfused and anastomosis parts of the intestine during different phases of the surgical procedure. Strategies for limiting motion and noise during acquisition were implemented. iPPG perfusion maps were successfully extracted from the intestine microvasculature, demonstrating that iPPG can be successfully used for detecting perturbations and perfusion changes in intestinal tissues during surgery. This study provides proof of concept for iPPG to detect changes in organ perfusion levels.<\/jats:p>","DOI":"10.3390\/jimaging8040094","type":"journal-article","created":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T01:34:29Z","timestamp":1648776869000},"page":"94","source":"Crossref","is-referenced-by-count":16,"title":["Imaging PPG for In Vivo Human Tissue Perfusion Assessment during Surgery"],"prefix":"10.3390","volume":"8","author":[{"given":"Marco","family":"Lai","sequence":"first","affiliation":[{"name":"IGT & US Devices & Systems, Philips Research, High Tech, Campus 34, 5656 AE Eindhoven, The Netherlands"},{"name":"Department of Electrical Engineering, Eindhoven University of Technology, 5600 MB Eindhoven, The Netherlands"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1687-2925","authenticated-orcid":false,"given":"Stefan D.","family":"van der Stel","sequence":"additional","affiliation":[{"name":"Faculty TNW, Group Nanobiophysics, Twente University, Drienorlaan 5, 7522 NB Enschede, The Netherlands"},{"name":"Department of Surgery, The Netherlands Cancer Institute\u2014Antoni van Leeuwenhoek, Plesmanlaan 121, Postbus 90203, 1066 CX Amsterdam, The Netherlands"}]},{"given":"Harald C.","family":"Groen","sequence":"additional","affiliation":[{"name":"Department of Surgery, The Netherlands Cancer Institute\u2014Antoni van Leeuwenhoek, Plesmanlaan 121, Postbus 90203, 1066 CX Amsterdam, The Netherlands"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5422-0143","authenticated-orcid":false,"given":"Mark","family":"van Gastel","sequence":"additional","affiliation":[{"name":"Department of Electrical Engineering, Eindhoven University of Technology, 5600 MB Eindhoven, The Netherlands"},{"name":"Patient Care & Monitoring, Philips Research, High Tech Campus 34, 5656 AE Eindhoven, The Netherlands"}]},{"given":"Koert F. D.","family":"Kuhlmann","sequence":"additional","affiliation":[{"name":"Department of Surgery, The Netherlands Cancer Institute\u2014Antoni van Leeuwenhoek, Plesmanlaan 121, Postbus 90203, 1066 CX Amsterdam, The Netherlands"}]},{"given":"Theo J. M.","family":"Ruers","sequence":"additional","affiliation":[{"name":"Faculty TNW, Group Nanobiophysics, Twente University, Drienorlaan 5, 7522 NB Enschede, The Netherlands"},{"name":"Department of Surgery, The Netherlands Cancer Institute\u2014Antoni van Leeuwenhoek, Plesmanlaan 121, Postbus 90203, 1066 CX Amsterdam, The Netherlands"}]},{"given":"Benno H. W.","family":"Hendriks","sequence":"additional","affiliation":[{"name":"IGT & US Devices & Systems, Philips Research, High Tech, Campus 34, 5656 AE Eindhoven, The Netherlands"},{"name":"Biomedical Engineering, Delft University of Technology, Mekelweg 5, 2628 CD Delft, The Netherlands"}]}],"member":"1968","published-online":{"date-parts":[[2022,3,31]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"R114","DOI":"10.1186\/cc13905","article-title":"Clinical assessment of peripheral perfusion to predict postoperative complications after major abdominal surgery early: A prospective observational study in adults","volume":"18","author":"Paauwe","year":"2014","journal-title":"Crit. 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