{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,24]],"date-time":"2025-03-24T07:59:08Z","timestamp":1742803148563},"reference-count":56,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2018,2,16]],"date-time":"2018-02-16T00:00:00Z","timestamp":1518739200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neuroinform."],"DOI":"10.3389\/fninf.2018.00002","type":"journal-article","created":{"date-parts":[[2018,2,16]],"date-time":"2018-02-16T08:49:21Z","timestamp":1518770961000},"update-policy":"http:\/\/dx.doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":91,"title":["Extremely Scalable Spiking Neuronal Network Simulation Code: From Laptops to Exascale Computers"],"prefix":"10.3389","volume":"12","author":[{"given":"Jakob","family":"Jordan","sequence":"first","affiliation":[]},{"given":"Tammo","family":"Ippen","sequence":"additional","affiliation":[]},{"given":"Moritz","family":"Helias","sequence":"additional","affiliation":[]},{"given":"Itaru","family":"Kitayama","sequence":"additional","affiliation":[]},{"given":"Mitsuhisa","family":"Sato","sequence":"additional","affiliation":[]},{"given":"Jun","family":"Igarashi","sequence":"additional","affiliation":[]},{"given":"Markus","family":"Diesmann","sequence":"additional","affiliation":[]},{"given":"Susanne","family":"Kunkel","sequence":"additional","affiliation":[]}],"member":"1965","published-online":{"date-parts":[[2018,2,16]]},"reference":[{"key":"B1","doi-asserted-by":"crossref","DOI":"10.1017\/CBO9780511574566","volume-title":"Corticonics: Neural Circuits of the Cerebral Cortex, 1st Edn","author":"Abeles","year":"1991"},{"key":"B2","doi-asserted-by":"publisher","first-page":"48","DOI":"10.3389\/fninf.2013.00048","article-title":"Nengo: a python tool for building large-scale functional brain models","volume":"7","author":"Bekolay","year":"2013","journal-title":"Front. Neuroinformatics"},{"volume-title":"Writing Efficient Programs","year":"1982","author":"Bentley","key":"B3"},{"key":"B4","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1109\/82.842110","article-title":"Point-to-point connectivity between neuromorphic chips using address events","volume":"47","author":"Boahen","year":"2000","journal-title":"IEEE Trans. Circ. Syst. II Analog Digit. Signal Process."},{"key":"B5","doi-asserted-by":"publisher","first-page":"1383","DOI":"10.4249\/scholarpedia.1383","article-title":"GENESIS (simulation environment)","volume":"2","author":"Bower","year":"2007","journal-title":"Scholarpedia"},{"key":"B6","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-662-02728-8","volume-title":"Anatomy of the Cortex: Statistics and Geometry","author":"Braitenberg","year":"1991"},{"key":"B7","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1016\/j.tics.2010.04.004","article-title":"Large-scale brain networks in cognition: emerging methods and principles","volume":"14","author":"Bressler","year":"2010","journal-title":"Trends Cogn. Sci."},{"key":"B8","doi-asserted-by":"publisher","first-page":"5","DOI":"10.14529\/jsfi140101","article-title":"Toward exascale resilience: 2014 update","volume":"1","author":"Cappello","year":"2014","journal-title":"Supercomput. Front. Innov."},{"key":"B9","doi-asserted-by":"crossref","DOI":"10.1017\/CBO9780511541612","volume-title":"The NEURON Book","author":"Carnevale","year":"2006"},{"key":"B10","doi-asserted-by":"publisher","first-page":"57","DOI":"10.3389\/fnana.2016.00057","article-title":"Automatic generation of connectivity for large-scale neuronal network models through structural plasticity","volume":"10","author":"Diaz-Pier","year":"2016","journal-title":"Front. Neuroanat"},{"key":"B11","first-page":"43","article-title":"NEST: an environment for neural systems simulations","volume-title":"Forschung und wisschenschaftliches Rechnen, Beitr\u00e4ge zum Heinz-Billing-Preis 2001, Volume 58 of GWDG-Bericht","author":"Diesmann","year":"2002"},{"volume-title":"SYNOD: An Environment for Neural Systems Simulations. Language Interface and Tutorial.","year":"1995","author":"Diesmann","key":"B12"},{"key":"B13","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1177\/1094342010391989","article-title":"The international exascale software project roadmap","volume":"25","author":"Dongarra","year":"2011","journal-title":"Int. J. High Perform. Comput. Appl."},{"key":"B14","doi-asserted-by":"publisher","first-page":"12","DOI":"10.3389\/neuro.11.012.2008","article-title":"PyNEST: a convenient interface to the NEST simulator","volume":"2","author":"Eppler","year":"2009","journal-title":"Front. Neuroinform."},{"key":"B15","article-title":"Scalable memory allocation using jemalloc","author":"Evans","year":"2011","journal-title":"Notes Facebook Eng."},{"key":"B16","doi-asserted-by":"publisher","first-page":"1430","DOI":"10.4249\/scholarpedia.1430","article-title":"NEST (NEural Simulation Tool)","volume":"2","author":"Gewaltig","year":"2007","journal-title":"Scholarpedia"},{"key":"B17","doi-asserted-by":"publisher","first-page":"10883","DOI":"10.4249\/scholarpedia.10883","article-title":"Brian simulator","volume":"8","author":"Goodman","year":"2013","journal-title":"Scholarpedia"},{"volume-title":"Introduction to High Performance Computing for Scientists and Engineers","year":"2011","author":"Hager","key":"B18"},{"key":"B19","doi-asserted-by":"publisher","first-page":"34","DOI":"10.3389\/fninf.2017.00034","article-title":"Integration of continuous-time dynamics in a spiking neural network simulator","volume":"11","author":"Hahne","year":"2017","journal-title":"Front Neuroinform"},{"key":"B20","doi-asserted-by":"publisher","first-page":"22","DOI":"10.3389\/fninf.2015.00022","article-title":"A unified framework for spiking and gap-junction interactions in distributed neuronal network simulations","volume":"9","author":"Hahne","year":"2015","journal-title":"Front Neuroinform"},{"key":"B21","doi-asserted-by":"publisher","first-page":"26","DOI":"10.3389\/fninf.2012.00026","article-title":"Supercomputers ready for use as discovery machines for neuroscience","volume":"6","author":"Helias","year":"2012","journal-title":"Front Neuroinform"},{"key":"B22","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1007\/PL00007964","article-title":"A quantitative analysis of the local connectivity between pyramidal neurons in layers 2\/3 of the rat visual cortex","volume":"2","author":"Hellwig","year":"2000","journal-title":"Biol. Cybernet."},{"key":"B23","doi-asserted-by":"publisher","first-page":"49","DOI":"10.3389\/fncom.2011.00049","article-title":"Comparison of neuronal spike exchange methods on a Blue Gene\/P supercomputer","volume":"5","author":"Hines","year":"2011","journal-title":"Front. Comput. Neurosci."},{"key":"B24","doi-asserted-by":"publisher","first-page":"30","DOI":"10.3389\/fninf.2017.00030","article-title":"Constructing neuronal network models in massively parallel environments","volume":"11","author":"Ippen","year":"2017","journal-title":"Front Neuroinformatics"},{"volume-title":"Numerical Solution of Partial Differential Equations by the Finite Element Method","year":"1987","author":"Johnson","key":"B25"},{"key":"B26","doi-asserted-by":"publisher","first-page":"1","DOI":"10.17815\/jlsrf-1-18","article-title":"JUQUEEN: IBM Blue Gene\/Q\u00ae supercomputer system at the J\u00fclich Supercomputing Centre","year":"2015","journal-title":"J. Large-Scale Res. Facil."},{"volume-title":"Principles of Neural Science, 3rd Edn","year":"1991","author":"Kandel","key":"B27"},{"key":"B28","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1007\/978-3-319-41321-1_19","article-title":"Leveraging a cluster-booster architecture for brain-scale simulations","volume-title":"International Conference on High Performance Computing","author":"Kumbhar","year":"2016"},{"key":"B29","doi-asserted-by":"publisher","first-page":"15","DOI":"10.3389\/fninf.2011.00015","article-title":"An ultrascalable solution to large-scale neural tissue simulation","volume":"5","author":"Kozloski","year":"2011","journal-title":"Front. Neuroinform."},{"journal-title":"Nest 2.12.0","year":"2017","author":"Kunkel","key":"B30"},{"key":"B31","doi-asserted-by":"publisher","first-page":"35","DOI":"10.3389\/fninf.2011.00035","article-title":"Meeting the memory challenges of brain-scale simulation","volume":"5","author":"Kunkel","year":"2012","journal-title":"Front. Neuroinform."},{"key":"B32","doi-asserted-by":"publisher","first-page":"40","DOI":"10.3389\/fninf.2017.00040","article-title":"The nest dry-run mode: efficient dynamic analysis of neuronal network simulation code","volume":"11","author":"Kunkel","year":"2017","journal-title":"Front. Neuroinform."},{"key":"B33","doi-asserted-by":"publisher","first-page":"78","DOI":"10.3389\/fninf.2014.00078","article-title":"Spiking network simulation code for petascale computers","volume":"8","author":"Kunkel","year":"2014","journal-title":"Front. Neuroinform."},{"key":"B34","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/978-94-007-3858-4_10","article-title":"Virtues, pitfalls, and methodology of neuronal network modeling and simulations on supercomputers","volume-title":"Computational Systems Neurobiology","author":"Lansner","year":"2012"},{"key":"B35","doi-asserted-by":"publisher","first-page":"2063","DOI":"10.1162\/NECO_a_00876","article-title":"Simulation neurotechnologies for advancing brain research: parallelizing large networks in neuron","volume":"28","author":"Lytton","year":"2016","journal-title":"Neural Comput."},{"key":"B36","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1093\/cercor\/bhs270","article-title":"A weighted and directed interareal connectivity matrix for macaque cerebral cortex","volume":"24","author":"Markov","year":"2014","journal-title":"Cereb. Cortex"},{"volume-title":"MPI: A Message-Passing Interface Standard.","year":"2009","key":"B37"},{"key":"B38","first-page":"255","article-title":"Overview of the K computer System","volume":"48","author":"Miyazaki","year":"2012","journal-title":"Fujitsu Sci. Tech. J."},{"key":"B39","doi-asserted-by":"publisher","first-page":"1437","DOI":"10.1162\/neco.2007.19.6.1437","article-title":"Spike-timing-dependent plasticity in balanced random networks","volume":"19","author":"Morrison","year":"2007","journal-title":"Neural Comput."},{"key":"B40","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1007\/s00422-008-0233-1","article-title":"Phenomenological models of synaptic plasticity based on spike-timing","volume":"98","author":"Morrison","year":"2008","journal-title":"Biol. Cybern."},{"key":"B41","doi-asserted-by":"publisher","first-page":"1776","DOI":"10.1162\/0899766054026648","article-title":"Advancing the boundaries of high-connectivity network simulation with distributed computing","volume":"17","author":"Morrison","year":"2005","journal-title":"Neural Comput."},{"key":"B42","doi-asserted-by":"publisher","first-page":"e1000456","DOI":"10.1371\/journal.pcbi.1000456","article-title":"Towards reproducible descriptions of neuronal network models","volume":"5","author":"Nordlie","year":"2009","journal-title":"PLoS Comput. Biol."},{"key":"B43","unstructured":"OpenMP Application Program Interface2008"},{"key":"B44","first-page":"93","article-title":"NESTML: a modeling language for spiking neurons","volume-title":"Modellierung 2016 Conference, Vol. 254 of LNI","author":"Plotnikov","year":"2016"},{"key":"B45","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1093\/cercor\/bhs358","article-title":"The cell-type specific cortical microcircuit: Relating structure and activity in a full-scale spiking network model","volume":"24","author":"Potjans","year":"2014","journal-title":"Cereb. Cortex"},{"key":"B46","doi-asserted-by":"publisher","first-page":"141","DOI":"10.3389\/fncom.2010.00141","article-title":"Enabling functional neural circuit simulations with distributed computing of neuromodulated plasticity","volume":"4","author":"Potjans","year":"2010","journal-title":"Front. Comput. Neurosci."},{"key":"B47","doi-asserted-by":"publisher","first-page":"10","DOI":"10.3389\/fninf.2013.00010","article-title":"The virtual brain: a simulator of primate brain network dynamics","volume":"7","author":"Sanz Leon","year":"2013","journal-title":"Front. Neuroinform."},{"key":"B48","article-title":"Performance model for large\u2013scale neural simulations with NEST","volume-title":"Extended Poster Abstracts of the SC14 Conference for Supercomputing","author":"Schenck","year":"2014"},{"key":"B49","article-title":"Full-density multi-scale account of structure and dynamics of macaque visual cortex","author":"Schmidt","year":"2016","journal-title":"arXiv preprint arXiv:1511.09364v4"},{"key":"B50","article-title":"From randomly connected to spatially organized multi-layered cortical network models","volume-title":"11th Goettingen Meeting of the German Neuroscience Society","author":"Senk","year":"2015"},{"key":"B51","doi-asserted-by":"publisher","first-page":"3555","DOI":"10.1073\/pnas.0810390106","article-title":"The fractions of short- and long-range connections in the visual cortex","volume":"106","author":"Stepanyants","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B52","first-page":"14","article-title":"Mpi at exascale","volume":"2","author":"Thakur","year":"2010","journal-title":"Proc. SciDAC"},{"key":"B53","doi-asserted-by":"publisher","first-page":"e1004490","DOI":"10.1371\/journal.pcbi.1004490","article-title":"Scalability of asynchronous networks is limited by one-to-one mapping between effective connectivity and correlations","volume":"11","author":"van Albada","year":"2015","journal-title":"PLoS Comput. Biol."},{"key":"B54","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1007\/978-3-319-12084-3_3","article-title":"Integrating brain structure and dynamics on supercomputers","volume-title":"Brain-Inspired Computing","author":"van Albada","year":"2014"},{"key":"B55","doi-asserted-by":"publisher","first-page":"15","DOI":"10.3389\/neuro.11.015.2009","article-title":"STEPS: modeling and simulating complex reaction-diffusion systems with Python","volume":"3","author":"Wils","year":"2009","journal-title":"Front. Neuroinformatics."},{"key":"B56","doi-asserted-by":"publisher","first-page":"23","DOI":"10.3389\/fninf.2014.00023","article-title":"CyNEST: a maintainable Cython-based interface for the NEST simulator","volume":"8","author":"Zaytsev","year":"2014","journal-title":"Front. Neuroinform."}],"updated-by":[{"updated":{"date-parts":[[2018,7,4]],"date-time":"2018-07-04T00:00:00Z","timestamp":1530662400000},"DOI":"10.3389\/fninf.2018.00034","type":"corrigendum","source":"publisher","label":"Corrigendum"}],"container-title":["Frontiers in Neuroinformatics"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fninf.2018.00002\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,28]],"date-time":"2020-10-28T06:22:17Z","timestamp":1603866137000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fninf.2018.00002\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2,16]]},"references-count":56,"alternative-id":["10.3389\/fninf.2018.00002"],"URL":"https:\/\/doi.org\/10.3389\/fninf.2018.00002","relation":{},"ISSN":["1662-5196"],"issn-type":[{"type":"electronic","value":"1662-5196"}],"subject":[],"published":{"date-parts":[[2018,2,16]]}}}