{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,6,12]],"date-time":"2022-06-12T14:11:01Z","timestamp":1655043061275},"reference-count":17,"publisher":"Walter de Gruyter GmbH","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,5]]},"abstract":"Zusammenfassung<\/jats:title>\n Die vorliegende Arbeit stellt eine neue bildbasierte Methode zur automatischen Klassifikation der Spontanbewegung und des Herzschlags in toxikologisch behandelten Zebrab\u00e4rblingslarven vor, die sich f\u00fcr Hochdurchsatz-Verfahren in der Toxikologie eignet. Dabei werden neue Akquisestrategien vorgeschlagen, Merkmale aus Bildzeitreihen extrahiert und Klassifikatoren entworfen. Diese werden iterativ kombiniert und anhand von drei Substanzen prototypisch experimentell erprobt.<\/jats:p>","DOI":"10.1524\/auto.2011.0921","type":"journal-article","created":{"date-parts":[[2011,4,26]],"date-time":"2011-04-26T08:21:49Z","timestamp":1303806109000},"page":"259-268","source":"Crossref","is-referenced-by-count":0,"title":["Automatische Klassifikation von Bildzeitreihen f\u00fcr toxikologische Hochdurchsatz-Untersuchungen"],"prefix":"10.1524","volume":"59","author":[{"given":"R\u00fcdiger","family":"Alshut","sequence":"first","affiliation":[]},{"given":"Ralf","family":"Mikut","sequence":"additional","affiliation":[{"name":"Karlsruher Institut f\u00fcr Technologie, Institut f\u00fcr Angewandte Informatik, Eggenstein-Leopoldshafen, Deutschland"}]},{"given":"Jessica","family":"Legradi","sequence":"additional","affiliation":[{"name":"Karslruher Institut f\u00fcr Technologie, Institut f\u00fcr Toxikologie und Genetik, Eggenstein-Leopoldshafen"}]},{"given":"Urban","family":"Liebel","sequence":"additional","affiliation":[{"name":"Karlsruher Institut f\u00fcr Technologie, Institut f\u00fcr Toxikologie und Genetik, Eggenstein-Leopoldshafen"}]},{"given":"Uwe","family":"Str\u00e4hle","sequence":"additional","affiliation":[{"name":"Karlsruher Institut f\u00fcr Technologie, Institut f\u00fcr Toxikologie und Genetik, Eggenstein-Leopoldshafen"}]},{"given":"Georg","family":"Bretthauer","sequence":"additional","affiliation":[{"name":"Karlsruher Institut f\u00fcr Technologie, Institut f\u00fcr Angewandte Informatik, Eggenstein-Leopoldshafen, Deutschland"}]},{"given":"Markus","family":"Reischl","sequence":"additional","affiliation":[{"name":"Karlsruher Institut f\u00fcr Technologie, Institut f\u00fcr Angewandte Informatik, Eggenstein-Leopoldshafen, Deutschland"}]}],"member":"374","published-online":{"date-parts":[[2011,4,26]]},"reference":[{"issue":"5","key":"p_1","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1038\/nrg2091","volume":"8","author":"Lieschke G. 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