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However, only few efforts have been made to offer scientists an alternative to the standard compartmentalized tools they use to explore their data and that involve a regular back and forth between them. We propose here an integrated pipeline especially designed for immersive environments, promoting direct interactions on semantically linked 2D and 3D heterogeneous data, displayed in a common working space. The creation of a semantic definition describing the content and the context of a molecular scene leads to the creation of an intelligent system where data are (1) combined through pre-existing or inferred links present in our hierarchical definition of the concepts, (2) enriched with suitable and adaptive analyses proposed to the user with respect to the current task and (3) interactively presented in a unique working environment to be explored.<\/jats:p>","DOI":"10.1515\/jib-2018-0004","type":"journal-article","created":{"date-parts":[[2018,7,12]],"date-time":"2018-07-12T11:05:38Z","timestamp":1531393538000},"source":"Crossref","is-referenced-by-count":19,"title":["Semantics for an Integrative and Immersive Pipeline Combining Visualization and Analysis of Molecular Data"],"prefix":"10.1515","volume":"15","author":[{"ORCID":"http:\/\/orcid.org\/0000-0001-6337-581X","authenticated-orcid":false,"given":"Mikael","family":"Trellet","sequence":"first","affiliation":[{"name":"Faculty of Science, Chemistry, Computational Structural Biology group, Bijvoet Center for Biomolecular Research , Padualaan 9 , 3584CH Utrecht , Netherlands"}]},{"given":"Nicolas","family":"F\u00e9rey","sequence":"additional","affiliation":[{"name":"VENISE Group, LIMSI, CNRS, Universit\u00e9 Paris Sud , Orsay , France"}]},{"given":"Jakub","family":"Floty\u0144ski","sequence":"additional","affiliation":[{"name":"Pozna\u0144 Univ. of Economics and Business , Pozna\u0144 , Poland"}]},{"given":"Marc","family":"Baaden","sequence":"additional","affiliation":[{"name":"Laboratoire de Biochimie Th\u00e9orique, CNRS, UPR9080, Institut de Biologie Physico-Chimique, Univ Paris Diderot, Sorbonne Paris Cit\u00e9, PSL Research University , Paris , France"}]},{"given":"Patrick","family":"Bourdot","sequence":"additional","affiliation":[{"name":"VENISE Group, LIMSI, CNRS, Universit\u00e9 Paris Sud , Orsay , France"}]}],"member":"374","published-online":{"date-parts":[[2018,7,9]]},"reference":[{"key":"2023033120302591203_j_jib-2018-0004_ref_001_w2aab3b7b2b1b6b1ab1b8b1Aa","doi-asserted-by":"crossref","unstructured":"Zhao G, Perilla JR, Yufenyuy EL, Meng X, Chen B, Ning J, et al. 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