{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,12,4]],"date-time":"2024-12-04T15:36:43Z","timestamp":1733326603461,"version":"3.30.1"},"update-to":[{"updated":{"date-parts":[[2023,9,27]],"date-time":"2023-09-27T00:00:00Z","timestamp":1695772800000},"DOI":"10.1371\/journal.pcbi.1011473","type":"new_version","label":"New version"}],"reference-count":84,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T00:00:00Z","timestamp":1694390400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000269","name":"Economic and Social Research Council","doi-asserted-by":"publisher","award":["ES\/P000630\/1"],"id":[{"id":"10.13039\/501100000269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000275","name":"Leverhulme Trust","doi-asserted-by":"publisher","award":["Fellowship"],"id":[{"id":"10.13039\/501100000275","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.ploscompbiol.org"],"crossmark-restriction":false},"short-container-title":["PLoS Comput Biol"],"abstract":"Several competing neuro-computational theories of autism have emerged from predictive coding models of the brain. To disentangle their subtly different predictions about the nature of atypicalities in autistic perception, we performed computational modelling of two sensorimotor tasks: the predictive use of manual gripping forces during object lifting and anticipatory eye movements during a naturalistic interception task. In contrast to some accounts, we found no evidence of chronic atypicalities in the use of priors or weighting of sensory information during object lifting. Differences in prior beliefs, rates of belief updating, and the precision weighting of prediction errors were, however, observed for anticipatory eye movements. Most notably, we observed autism-related difficulties in flexibly adapting learning rates in response to environmental change (i.e., volatility). These findings suggest that atypical encoding of precision and context-sensitive adjustments provide a better explanation of autistic perception than generic attenuation of priors or persistently high precision prediction errors. Our results did not, however, support previous suggestions that autistic people perceive their environment to be persistently volatile.<\/jats:p>","DOI":"10.1371\/journal.pcbi.1011473","type":"journal-article","created":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T17:29:18Z","timestamp":1694453358000},"page":"e1011473","update-policy":"https:\/\/doi.org\/10.1371\/journal.pcbi.corrections_policy","source":"Crossref","is-referenced-by-count":4,"title":["Testing predictive coding theories of autism spectrum disorder using models of active inference"],"prefix":"10.1371","volume":"19","author":[{"given":"Tom","family":"Arthur","sequence":"first","affiliation":[]},{"given":"Sam","family":"Vine","sequence":"additional","affiliation":[]},{"given":"Gavin","family":"Buckingham","sequence":"additional","affiliation":[]},{"given":"Mark","family":"Brosnan","sequence":"additional","affiliation":[]},{"given":"Mark","family":"Wilson","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3880-3856","authenticated-orcid":true,"given":"David","family":"Harris","sequence":"additional","affiliation":[]}],"member":"340","published-online":{"date-parts":[[2023,9,11]]},"reference":[{"key":"pcbi.1011473.ref001","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1038\/nrn.2017.112","article-title":"Sensory perception in autism.","volume":"18","author":"CE Robertson","year":"2017","journal-title":"Nat Rev Neurosci"},{"key":"pcbi.1011473.ref002","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1177\/1362361309103794","article-title":"Sensory processing in adults with autism spectrum disorders.","volume":"13","author":"L Crane","year":"2009","journal-title":"Autism"},{"key":"pcbi.1011473.ref003","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1177\/1362361307075702","article-title":"Sensory correlations in autism.","volume":"11","author":"JK Kern","year":"2007","journal-title":"Autism"},{"key":"pcbi.1011473.ref004","first-page":"217","article-title":"Autistic disturbances of affective contact","volume":"2","author":"L. 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