乐胖代购免代理版

{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T00:54:59Z","timestamp":1717980899743},"reference-count":129,"publisher":"Springer Science and Business Media LLC","issue":"1","funder":[{"name":"BioMedBridges","award":["284209"]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Med Inform Decis Mak"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1186\/s12911-017-0424-6","type":"journal-article","created":{"date-parts":[[2017,3,23]],"date-time":"2017-03-23T02:22:53Z","timestamp":1490235773000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Orchestrating differential data access for translational research: a pilot implementation"],"prefix":"10.1186","volume":"17","author":[{"ORCID":"http:\/\/orcid.org\/0000-0002-5427-2496","authenticated-orcid":false,"given":"Marco","family":"Brandizi","sequence":"first","affiliation":[]},{"given":"Olga","family":"Melnichuk","sequence":"additional","affiliation":[]},{"given":"Raffael","family":"Bild","sequence":"additional","affiliation":[]},{"given":"Florian","family":"Kohlmayer","sequence":"additional","affiliation":[]},{"given":"Benedicto","family":"Rodriguez-Castro","sequence":"additional","affiliation":[]},{"given":"Helmut","family":"Spengler","sequence":"additional","affiliation":[]},{"given":"Klaus A.","family":"Kuhn","sequence":"additional","affiliation":[]},{"given":"Wolfgang","family":"Kuchinke","sequence":"additional","affiliation":[]},{"given":"Christian","family":"Ohmann","sequence":"additional","affiliation":[]},{"given":"Timo","family":"Mustonen","sequence":"additional","affiliation":[]},{"given":"Mikael","family":"Linden","sequence":"additional","affiliation":[]},{"given":"Tommi","family":"Nyr\u00f6nen","sequence":"additional","affiliation":[]},{"given":"Ilkka","family":"Lappalainen","sequence":"additional","affiliation":[]},{"given":"Alvis","family":"Brazma","sequence":"additional","affiliation":[]},{"given":"Ugis","family":"Sarkans","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2017,3,23]]},"reference":[{"key":"424_CR1","first-page":"211","volume":"299","author":"SH Woolf","year":"2008","unstructured":"Woolf SH. The meaning of translational research and why it matters. JAMA. 2008;299:211\u20133.","journal-title":"JAMA"},{"key":"424_CR2","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1016\/j.nhtm.2014.12.002","volume":"2","author":"RJ Cohrs","year":"2015","unstructured":"Cohrs RJ, Tyler M, Parviz G, Luc B, Higgins PJ, Aamir S. Translational medicine definition by the european society for translational medicine. New Horizons Transl Med. 2015;2:86\u20138.","journal-title":"New Horizons Transl Med"},{"key":"424_CR3","doi-asserted-by":"publisher","first-page":"802","DOI":"10.1038\/gim.2013.121","volume":"15","author":"CG Chute","year":"2013","unstructured":"Chute CG, Ullman-Cullere M, Wood GM, Lin SM, He M, Pathak J. Some experiences and opportunities for big data in translational research. Genet Med. 2013;15:802\u20139.","journal-title":"Genet Med"},{"key":"424_CR4","doi-asserted-by":"publisher","first-page":"90cm17","DOI":"10.1126\/scitranslmed.3002747","volume":"3","author":"FS Collins","year":"2011","unstructured":"Collins FS. Reengineering translational science: the time is right. Sci Transl Med. 2011;3:90cm17.","journal-title":"Sci Transl Med"},{"key":"424_CR5","doi-asserted-by":"publisher","first-page":"797","DOI":"10.1002\/humu.22066","volume":"33","author":"T Beck","year":"2012","unstructured":"Beck T, Tim B, Sirisha G, S\u00f8ren B, Norbert G, Lemke HU, et al. Knowledge engineering for health: a new discipline required to bridge the \u2018ICT gap\u2019 between research and healthcare. Hum Mutat. 2012;33:797\u2013802.","journal-title":"Hum Mutat"},{"key":"424_CR6","unstructured":"Murphy SN, Mendis M, Hackett K, Kuttan R, Pan W, Phillips LC, et al. Architecture of the open-source clinical research chart from Informatics for Integrating Biology and the Bedside. AMIA Annu Symp Proc. 2007. p 548\u201352. https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2655844\/ ."},{"key":"424_CR7","doi-asserted-by":"publisher","first-page":"1651","DOI":"10.1056\/NEJMhle1309073","volume":"369","author":"MM Mello","year":"2013","unstructured":"Mello MM, Francer JK, Wilenzick M, Teden P, Bierer BE, Barnes M. Preparing for responsible sharing of clinical trial data. N Engl J Med. 2013;369:1651\u20138.","journal-title":"N Engl J Med"},{"key":"424_CR8","doi-asserted-by":"publisher","first-page":"1171","DOI":"10.1136\/bmj.326.7400.1171","volume":"326","author":"H Melander","year":"2003","unstructured":"Melander H, Ahlqvist-Rastad J, Meijer G, Beermann B. Evidence b (i) ased medicine\u2014selective reporting from studies sponsored by pharmaceutical industry: review of studies in new drug applications. BMJ Br Medical J Publ Group. 2003;326:1171\u20133.","journal-title":"BMJ Br Medical J Publ Group"},{"key":"424_CR9","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1186\/1745-6215-12-249","volume":"12","author":"PC G\u00f8tzsche","year":"2011","unstructured":"G\u00f8tzsche PC. Why we need easy access to all data from all clinical trials and how to accomplish it. Trials. 2011;12:249.","journal-title":"Trials"},{"key":"424_CR10","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1197\/jamia.M2273","volume":"14","author":"C Safran","year":"2007","unstructured":"Safran C, Bloomrosen M, Hammond WE, Labkoff S, Markel-Fox S, Tang PC, et al. Toward a national framework for the secondary use of health data: an american medical informatics association white paper. J Am Med Inform Assoc. 2007;14:1\u20139.","journal-title":"J Am Med Inform Assoc"},{"key":"424_CR11","doi-asserted-by":"publisher","first-page":"1001","DOI":"10.1101\/gr.120329.111","volume":"21","author":"AL McGuire","year":"2011","unstructured":"McGuire AL, Basford M, Dressler LG, Fullerton SM, Koenig BA, Li R, et al. Ethical and practical challenges of sharing data from genome-wide association studies: the eMERGE consortium experience. Genome Res. 2011;21:1001\u20137.","journal-title":"Genome Res"},{"key":"424_CR12","doi-asserted-by":"publisher","first-page":"E58","DOI":"10.1371\/journal.pbio.0000058","volume":"1","author":"RC Hardison","year":"2003","unstructured":"Hardison RC. Comparative genomics. PLoS Biol. 2003;1:E58.","journal-title":"PLoS Biol"},{"key":"424_CR13","volume-title":"Medical Law and ethics","author":"J Herring","year":"2014","unstructured":"Herring J. Medical Law and ethics. USA: Oxford University Press; 2014."},{"key":"424_CR14","doi-asserted-by":"publisher","unstructured":"Chadwick R, Levitt M, Shickle D. The Right to Know and the Right Not to Know: Genetic Privacy and Responsibility. Cambridge: Cambridge University Press; 2014.","DOI":"10.1017\/CBO9781139875981"},{"key":"424_CR15","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1504\/IJIEM.2010.035624","volume":"6","author":"A Appari","year":"2010","unstructured":"Appari A, Ajit A, Johnson ME. Information security and privacy in healthcare: current state of research. Int J Internet Enterp Manag. 2010;6:279.","journal-title":"Int J Internet Enterp Manag"},{"key":"424_CR16","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1016\/j.jbi.2012.12.003","volume":"46","author":"JL Fern\u00e1ndez-Alem\u00e1n","year":"2013","unstructured":"Fern\u00e1ndez-Alem\u00e1n JL, Se\u00f1or IC, Lozoya P\u00c1O, Ambrosio T. Security and privacy in electronic health records: a systematic literature review. J Biomed Inform. 2013;46:541\u201362.","journal-title":"J Biomed Inform"},{"key":"424_CR17","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1016\/S1054-139X(02)00365-8","volume":"30","author":"ET Moolchan","year":"2002","unstructured":"Moolchan ET, Mermelstein R. Research on tobacco use among teenagers: ethical challenges. J Adolesc Health. 2002;30:409\u201317.","journal-title":"J Adolesc Health"},{"key":"424_CR18","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1289\/ehp.1103904","volume":"120","author":"A Harding","year":"2012","unstructured":"Harding A, Harper B, Stone D, O\u2019Neill C, Berger P, Harris S, et al. Conducting research with tribal communities: sovereignty, ethics, and data-sharing issues. Environ Health Perspect. 2012;120:6\u201310.","journal-title":"Environ Health Perspect"},{"key":"424_CR19","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1080\/13548500600595053","volume":"11","author":"MG Weiss","year":"2006","unstructured":"Weiss MG, Ramakrishna J, Somma D. Health-related stigma: rethinking concepts and interventions. Psychol Health Med. 2006;11:277\u201387.","journal-title":"Psychol Health Med"},{"key":"424_CR20","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/j.socscimed.2013.09.023","volume":"103","author":"JE Cook","year":"2014","unstructured":"Cook JE, Purdie-Vaughns V, Meyer IH, Busch JTA. Intervening within and across levels: a multilevel approach to stigma and public health. Soc Sci Med. 2014;103:101\u20139.","journal-title":"Soc Sci Med"},{"key":"424_CR21","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1056\/NEJMra012577","volume":"349","author":"EW Clayton","year":"2003","unstructured":"Clayton EW. Ethical, legal, and social implications of genomic medicine. N Engl J Med. 2003;349:562\u20139.","journal-title":"N Engl J Med"},{"key":"424_CR22","doi-asserted-by":"publisher","first-page":"1405","DOI":"10.1016\/S0140-6736(02)11394-8","volume":"360","author":"J Collier","year":"2002","unstructured":"Collier J, Iheanacho I. The pharmaceutical industry as an informant. Lancet. 2002;360:1405\u20139.","journal-title":"Lancet"},{"key":"424_CR23","doi-asserted-by":"publisher","first-page":"e1001201","DOI":"10.1371\/journal.pmed.1001201","volume":"9","author":"P Doshi","year":"2012","unstructured":"Doshi P, Jefferson T, Del Mar C. The imperative to share clinical study reports: recommendations from the tamiflu experience. PLoS Med. 2012;9:e1001201.","journal-title":"PLoS Med"},{"key":"424_CR24","doi-asserted-by":"publisher","first-page":"886","DOI":"10.1093\/bioinformatics\/btt066","volume":"29","author":"L Kamm","year":"2013","unstructured":"Kamm L, Bogdanov D, Laur S, Vilo J. A new way to protect privacy in large-scale genome-wide association studies. Bioinformatics. 2013;29:886\u201393.","journal-title":"Bioinformatics"},{"key":"424_CR25","volume-title":"Balancing privacy, autonomy, and scientific needs in electronic health records research","author":"S Hoffman","year":"2011","unstructured":"Hoffman S, Podgurski A. Balancing privacy, autonomy, and scientific needs in electronic health records research. 2011."},{"key":"424_CR26","unstructured":"Broeder D, Jones B, Kelsey D, Kershaw P, L\u00fcders S, Lyall A, et al. Federated identity management for research collaborations. CERN; 2013. http:\/\/cds.cern.ch\/record\/1442597\/files\/CERN-OPEN-2012-006.pdf . Accessed 16 Mar 2017."},{"key":"424_CR27","unstructured":"Bertino E, Takahashi K. Identity Management: Concepts, Technologies, and Systems. Boston: Artech House; 2011."},{"key":"424_CR28","volume-title":"Analyzing recent trends in enterprise identity management. 2014 25th international workshop on database and expert systems applications","author":"M Kunz","year":"2014","unstructured":"Kunz M, Michael K, Matthias H, Ludwig F, Michael N, Gunther P. Analyzing recent trends in enterprise identity management. 2014 25th international workshop on database and expert systems applications. 2014. http:\/\/dx.doi.org\/10.1109\/dexa.2014.62 . Accessed 16 Mar 2017."},{"key":"424_CR29","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1016\/j.csi.2013.12.010","volume":"36","author":"C Kalloniatis","year":"2014","unstructured":"Kalloniatis C, Christos K, Haralambos M, Manousakis V, Shareeful I, Stefanos G, et al. Towards the design of secure and privacy-oriented information systems in the cloud: identifying the major concepts. Comput Stand Interfaces. 2014;36:759\u201375.","journal-title":"Comput Stand Interfaces"},{"key":"424_CR30","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1016\/j.is.2014.05.004","volume":"48","author":"B Fabian","year":"2015","unstructured":"Fabian B, Benjamin F, Tatiana E, Philipp J. Collaborative and secure sharing of healthcare data in multi-clouds. Inf Syst. 2015;48:132\u201350.","journal-title":"Inf Syst"},{"key":"424_CR31","first-page":"275","volume":"137","author":"F Falc\u00e3o-Reis","year":"2008","unstructured":"Falc\u00e3o-Reis F, Costa-Pereira A, Correia ME. Access and privacy rights using web security standards to increase patient empowerment. Stud Health Technol Inform. 2008;137:275\u201385.","journal-title":"Stud Health Technol Inform"},{"key":"424_CR32","volume-title":"A comprehensive privacy-aware authorization framework founded on HIPAA privacy rules. Proceedings of the ACM international conference on health informatics - IHI\u201910","author":"A AL Faresi","year":"2010","unstructured":"AL Faresi A, Duminda W, Khaled M. A comprehensive privacy-aware authorization framework founded on HIPAA privacy rules. Proceedings of the ACM international conference on health informatics - IHI\u201910. 2010. http:\/\/dx.doi.org\/10.1145\/1882992.1883093 . Accessed 16 Mar 2017."},{"key":"424_CR33","volume-title":"Realising the full potential of research data: common challenges in data management, sharing and integration across scientific disciplines","author":"L Field","year":"2013","unstructured":"Field L, Stephanie S, Jon I, Wittenburg P, Los W, Broeder D, Hardisty A, Repo S, Jenkinson A. Realising the full potential of research data: common challenges in data management, sharing and integration across scientific disciplines. 2013. http:\/\/dx.doi.org\/10.5281\/zenodo.7636 . Accessed 16 Mar 2017."},{"key":"424_CR34","volume-title":"BioMedBridges workshop on e-infrastructure support for the life sciences \u2013 preparing for the data deluge","author":"S Suhr","year":"2014","unstructured":"Suhr S, Cochrane G, Stanford NJ, Boiten J-W, Swedlow J, Morris C, et al. BioMedBridges workshop on e-infrastructure support for the life sciences \u2013 preparing for the data deluge. 2014. http:\/\/dx.doi.org\/10.5281\/zenodo.13942 . Accessed 16 Mar 2017."},{"key":"424_CR35","unstructured":"ELIXIR, EU-OPENSCREEN, BBMRI, EATRIS, ECRIN, INFRAFRONTIER, et al. Principles of data management and sharing at European Research Infrastructures. http:\/\/dx.doi.org\/10.5281\/zenodo.8304. . Accessed 16 Mar 2017."},{"key":"424_CR36","unstructured":"European Strategy Forum on Research Infrastructures. http:\/\/ec.europa.eu\/research\/infrastructures\/index_en.cfm?pg=esfri . Accessed 13 Feb 2017."},{"key":"424_CR37","unstructured":"Burdett T, Parkinson H, Juty N, Liener T, Conte N, Brandizi M, et al. BioMedBridges: Harmonisation of semantic standards supporting use cases from WP7 and WP10, report. BioMedBridges; 2016. http:\/\/dx.doi.org\/10.5281\/zenodo.45920 . Accessed 16 Mar 2017."},{"key":"424_CR38","unstructured":"BioMedBridges Deliverables. http:\/\/www.biomedbridges.eu\/deliverables . Accessed 13 Feb 2017."},{"key":"424_CR39","unstructured":"Brandizi M, Melnichuk O, Sarkans U, Bild R, Kohlmayer F, Rodriguez-Castro B, et al. BioMedBridges: Implementation of a pilot for the security framework. BioMedBridges Project; 2016. http:\/\/dx.doi.org\/10.5281\/zenodo.45927 . Accessed 16 Mar 2017."},{"key":"424_CR40","unstructured":"Bild R, Kohlmayer F, Brunner S, Kuhn K, Rodriguez-Castro B, Lamichhane A, et al. BioMedBridges security architecture and framework. BioMedBridges; 2014. http:\/\/dx.doi.org\/10.5281\/zenodo.11953 . Accessed 16 Mar 2017."},{"key":"424_CR41","unstructured":"Report on regulations, privacy and security requirements. BioMedBridges; 2013. http:\/\/www.biomedbridges.eu\/deliverables\/51-0 . Accessed 16 Mar 2017."},{"key":"424_CR42","unstructured":"Tool for assessment of regulatory and ethical requirements; including supportive documents. BioMedBridges; 2013. http:\/\/www.biomedbridges.eu\/deliverables\/52-0 . Accessed 16 Mar 2017."},{"key":"424_CR43","doi-asserted-by":"publisher","first-page":"D64","DOI":"10.1093\/nar\/gkr937","volume":"40","author":"M Gostev","year":"2012","unstructured":"Gostev M, Faulconbridge A, Brandizi M, Fernandez-Banet J, Sarkans U, Brazma A, et al. The BioSample database (BioSD) at the european bioinformatics institute. Nucleic Acids Res. 2012;40:D64\u201370.","journal-title":"Nucleic Acids Res"},{"key":"424_CR44","doi-asserted-by":"publisher","first-page":"D50","DOI":"10.1093\/nar\/gkt1081","volume":"42","author":"A Faulconbridge","year":"2014","unstructured":"Faulconbridge A, Burdett T, Brandizi M, Gostev M, Pereira R, Vasant D, et al. Updates to BioSamples database at european bioinformatics institute. Nucleic Acids Res. 2014;42:D50\u20132.","journal-title":"Nucleic Acids Res"},{"key":"424_CR45","doi-asserted-by":"publisher","first-page":"D1113","DOI":"10.1093\/nar\/gku1057","volume":"43","author":"N Kolesnikov","year":"2015","unstructured":"Kolesnikov N, Hastings E, Keays M, Melnichuk O, Tang YA, Williams E, et al. ArrayExpress update--simplifying data submissions. Nucleic Acids Res. 2015;43:D1113\u20136.","journal-title":"Nucleic Acids Res"},{"key":"424_CR46","doi-asserted-by":"publisher","first-page":"D447","DOI":"10.1093\/nar\/gkv1145","volume":"44","author":"JA Vizca\u00edno","year":"2016","unstructured":"Vizca\u00edno JA, Csordas A, Del-Toro N, Dianes JA, Griss J, Lavidas I, et al. 2016 update of the PRIDE database and its related tools. Nucleic Acids Res. 2016;44:D447\u201356.","journal-title":"Nucleic Acids Res"},{"key":"424_CR47","doi-asserted-by":"publisher","first-page":"D805","DOI":"10.1093\/nar\/gku1075","volume":"43","author":"SA Forbes","year":"2014","unstructured":"Forbes SA, Beare D, Gunasekaran P, Leung K, Bindal N, Boutselakis H, et al. COSMIC: exploring the world\u2019s knowledge of somatic mutations in human cancer. Nucleic Acids Res. 2014;43:D805\u201311.","journal-title":"Nucleic Acids Res"},{"key":"424_CR48","unstructured":"BBMRI-ERIC. http:\/\/www.bbmri-eric.eu . Accessed 13 Feb 2017."},{"key":"424_CR49","unstructured":"BBMRI-LPC Project. http:\/\/www.bbmri-lpc.org . Accessed 14 Feb 2017."},{"key":"424_CR50","unstructured":"BBMRI-LPC Biobanks. http:\/\/www.bbmri-lpc-biobanks.eu\/cataloque.html . Accessed 14 Feb 2017."},{"key":"424_CR51","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1089\/bio.2012.0003","volume":"10","author":"L Norlin","year":"2012","unstructured":"Norlin L, Fransson MN, Eriksson M, Merino-Martinez R, Anderberg M, Kurtovic S, et al. A minimum data Set for sharing biobank samples, information, and data: MIABIS. Biopreserv Biobank. 2012;10:343\u20138.","journal-title":"Biopreserv Biobank"},{"key":"424_CR52","unstructured":"BBMRI BMB Prototype. https:\/\/shibboleth.imse.med.tum.de . Accessed 14 Feb 2017."},{"key":"424_CR53","unstructured":"Resource Entitlement Management System (REMS). https:\/\/confluence.csc.fi\/display\/REMS\/Home . Accessed 14 Feb 2017."},{"key":"424_CR54","volume-title":"Resource entitlement management system","author":"M Linden","year":"2013","unstructured":"Linden M, Nyr\u00f6nen T, Lappalainen I. Resource entitlement management system. 2013. http:\/\/tnc2013.terena.org\/getfile\/870 . Accessed 16 Mar 2017."},{"key":"424_CR55","doi-asserted-by":"publisher","first-page":"692","DOI":"10.1038\/ng.3312","volume":"47","author":"I Lappalainen","year":"2015","unstructured":"Lappalainen I, Almeida-King J, Kumanduri V, Senf A, Spalding JD, Ur-Rehman S, et al. The european genome-phenome archive of human data consented for biomedical research. Nat Genet. 2015;47:692\u20135.","journal-title":"Nat Genet"},{"key":"424_CR56","unstructured":"Shibboleth. http:\/\/shibboleth.net . Accessed 16 Feb 2017."},{"key":"424_CR57","unstructured":"SAML Specifications. http:\/\/saml.xml.org\/saml-specifications . Accessed 14 Feb 2017."},{"key":"424_CR58","unstructured":"LIMPOPO SampleTAB Parser. https:\/\/github.com\/EBIBioSamples\/limpopo-sampletab . Accessed 14 Feb 2017."},{"key":"424_CR59","unstructured":"The BioSD Relational Database Loader. https:\/\/github.com\/EBIBioSamples\/biosd_model_load . Accessed 14 Feb 2017."},{"key":"424_CR60","doi-asserted-by":"publisher","first-page":"e1002554","DOI":"10.1371\/journal.pcbi.1002554","volume":"8","author":"K Pavelin","year":"2012","unstructured":"Pavelin K, Cham JA, de Matos P, Brooksbank C, Cameron G, Steinbeck C. Bioinformatics meets user-centred design: a perspective. PLoS Comput Biol. 2012;8:e1002554.","journal-title":"PLoS Comput Biol"},{"key":"424_CR61","unstructured":"SYMPOSIUM: Open bridges for life science data. http:\/\/www.biomedbridges.eu\/news\/symposium-open-bridges-life-science-data . Accessed 14 Feb 2017."},{"key":"424_CR62","unstructured":"BioSD Feature Annotator. https:\/\/github.com\/EBIBioSamples\/biosd_feature_annotator . Accessed 14 Feb 2017."},{"key":"424_CR63","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1007\/s00103-015-2300-9","volume":"59","author":"KA Kuhn","year":"2016","unstructured":"Kuhn KA, Bild R, Anton G, Schuffenhauer S, Wichmann H-E. Connecting biobanks of large european cohorts (EU project BBMRI-LPC). Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2016;59:385\u20139.","journal-title":"Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz"},{"key":"424_CR64","unstructured":"Shibboleth, Load Testing Contributed Results. https:\/\/wiki.shibboleth.net\/confluence\/display\/IDP30\/Load+Testing+Contributed+Results . Accessed 14 Feb 2017."},{"key":"424_CR65","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1186\/s13073-016-0323-y","volume":"8","author":"C Auffray","year":"2016","unstructured":"Auffray C, Balling R, Barroso I, Bencze L, Benson M, Bergeron J, et al. Making sense of big data in health research: towards an EU action plan. Genome Med. 2016;8:71.","journal-title":"Genome Med"},{"key":"424_CR66","unstructured":"Introduction to ELIXIR-EXCELERATE. https:\/\/www.elixir-europe.org\/events\/introduction-elixir-excelerate . Accessed 14 Feb 2017."},{"key":"424_CR67","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1016\/j.tibtech.2012.02.002","volume":"30","author":"LC Crosswell","year":"2012","unstructured":"Crosswell LC, Thornton JM. ELIXIR: a distributed infrastructure for european biological data. Trends Biotechnol. 2012;30:241\u20132.","journal-title":"Trends Biotechnol"},{"key":"424_CR68","unstructured":"CORBEL, Participating Research Infrastructures. http:\/\/www.corbel-project.eu\/participants.html . Accessed 14 Feb 2017."},{"key":"424_CR69","unstructured":"Blomberg N. ELIXIR Webinar - Introduction to ELIXIR-EXCELERATE. 2015. https:\/\/www.youtube.com\/watch?v=M3OfkAG23Kk . Accessed 14 Feb 2017."},{"key":"424_CR70","unstructured":"Authentication and Authorisation for Research and Collaboration. https:\/\/aarc-project.eu . Accessed 14 Feb 2017."},{"key":"424_CR71","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/s00766-010-0115-7","volume":"16","author":"M Deng","year":"2010","unstructured":"Deng M, Mina D, Kim W, Riccardo S, Bart P, Wouter J. A privacy threat analysis framework: supporting the elicitation and fulfillment of privacy requirements. Requir Eng. 2010;16:3\u201332.","journal-title":"Requir Eng"},{"key":"424_CR72","first-page":"298","volume-title":"Security analysis of the SAML single sign-on browser\/artifact profile. Computer security applications conference, 2003. Proceedings. 19th annual","author":"T Gross","year":"2003","unstructured":"Gross T. Security analysis of the SAML single sign-on browser\/artifact profile. Computer security applications conference, 2003. Proceedings. 19th annual. 2003. p. 298\u2013307."},{"key":"424_CR73","volume-title":"509-the directory: public-key and attribute certificate frameworks. International telecommunication union","author":"Recommendation X","year":"2000","unstructured":"Recommendation X. 509-the directory: public-key and attribute certificate frameworks. International telecommunication union. 2000. http:\/\/www.itu.int\/rec\/T-REC-X.509 . Accessed 16 Mar 2017."},{"key":"424_CR74","volume-title":"Http over tls","author":"E Rescorla","year":"2000","unstructured":"Rescorla E. Http over tls. 2000. http:\/\/tools.ietf.org\/html\/rfc2818.html . Accessed 16 Mar 2017."},{"key":"424_CR75","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1109\/MCOM.2002.1039856","volume":"40","author":"RKC Chang","year":"2002","unstructured":"Chang RKC. Defending against flooding-based distributed denial-of-service attacks: a tutorial. IEEE Commun Mag. 2002;40:42\u201351.","journal-title":"IEEE Commun Mag"},{"key":"424_CR76","volume-title":"The essence of command injection attacks in web applications. Conference record of the 33rd ACM SIGPLAN-SIGACT symposium on principles of programming languages - POPL\u201906","author":"Z Su","year":"2006","unstructured":"Su Z, Zhendong S, Gary W. The essence of command injection attacks in web applications. Conference record of the 33rd ACM SIGPLAN-SIGACT symposium on principles of programming languages - POPL\u201906. 2006. http:\/\/dx.doi.org\/10.1145\/1111037.1111070 . Accessed 16 Mar 2017."},{"key":"424_CR77","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1109\/MSP.2004.84","volume":"2","author":"B Potter","year":"2004","unstructured":"Potter B, McGraw G. Software security testing. IEEE Secur Privacy Mag. 2004;2:81\u20135.","journal-title":"IEEE Secur Privacy Mag"},{"key":"424_CR78","doi-asserted-by":"crossref","unstructured":"Myers GJ, Sandler C, Badgett T. The Art of Software Testing. Hoboken: Wiley; 2011.","DOI":"10.1002\/9781119202486"},{"key":"424_CR79","volume-title":"Securing the e-health cloud. Proceedings of the ACM international conference on health informatics - IHI\u201910","author":"H L\u00f6hr","year":"2010","unstructured":"L\u00f6hr H, Hans L, Ahmad-Reza S, Marcel W. Securing the e-health cloud. Proceedings of the ACM international conference on health informatics - IHI\u201910. 2010. http:\/\/dx.doi.org\/10.1145\/1882992.1883024 . Accessed 16 Mar 2017."},{"key":"424_CR80","unstructured":"Release Attributes\u2026 For Science!. https:\/\/refeds.org\/a\/1154 . Accessed 14 Feb 2017."},{"key":"424_CR81","unstructured":"REFEDs ePSA usage comparison v0.13. https:\/\/blog.refeds.org\/wp-content\/uploads\/2015\/05\/ePSAcomparison_0_13.pdf . Accessed 14 Feb 2017."},{"key":"424_CR82","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1158\/2159-8290.CD-12-0095","volume":"2","author":"E Cerami","year":"2012","unstructured":"Cerami E, Gao J, Dogrusoz U, Gross BE, Sumer SO, Aksoy BA, et al. The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. Cancer Discov. 2012;2:401\u20134.","journal-title":"Cancer Discov"},{"key":"424_CR83","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1038\/sj.bjc.6601894","volume":"91","author":"S Bamford","year":"2004","unstructured":"Bamford S, Dawson E, Forbes S, Clements J, Pettett R, Dogan A, et al. The COSMIC (catalogue of somatic mutations in cancer) database and website. Br J Cancer. 2004;91:355\u20138.","journal-title":"Br J Cancer"},{"key":"424_CR84","doi-asserted-by":"publisher","first-page":"D57","DOI":"10.1093\/nar\/gkr1163","volume":"40","author":"T Barrett","year":"2012","unstructured":"Barrett T, Clark K, Gevorgyan R, Gorelenkov V, Gribov E, Karsch-Mizrachi I, et al. BioProject and BioSample databases at NCBI: facilitating capture and organization of metadata. Nucleic Acids Res. 2012;40:D57\u201363.","journal-title":"Nucleic Acids Res"},{"key":"424_CR85","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1093\/bib\/bbr051","volume":"12","author":"A Splendiani","year":"2011","unstructured":"Splendiani A, G\u00fcndel M, Austyn JM, Cavalieri D, Scognamiglio C, Brandizi M. Knowledge sharing and collaboration in translational research, and the DC-THERA directory. Brief Bioinform. 2011;12:562\u201375.","journal-title":"Brief Bioinform"},{"key":"424_CR86","doi-asserted-by":"publisher","first-page":"bar067","DOI":"10.1093\/database\/bar067","volume":"2012","author":"N Vasilevsky","year":"2012","unstructured":"Vasilevsky N, Johnson T, Corday K, Torniai C, Brush M, Segerdell E, et al. Research resources: curating the new eagle-i discovery system. Database. 2012;2012:bar067.","journal-title":"Database"},{"key":"424_CR87","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1093\/bib\/bbu006","volume":"16","author":"V Canuel","year":"2015","unstructured":"Canuel V, Rance B, Avillach P, Degoulet P, Burgun A. Translational research platforms integrating clinical and omics data: a review of publicly available solutions. Brief Bioinform. 2015;16:280\u201390.","journal-title":"Brief Bioinform"},{"key":"424_CR88","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1089\/bio.2010.0003","volume":"7","author":"J Vaught","year":"2009","unstructured":"Vaught J, Kelly A, Hewitt R. A review of international biobanks and networks: success factors and key benchmarks. Biopreserv Biobank. 2009;7:143\u201350.","journal-title":"Biopreserv Biobank"},{"key":"424_CR89","first-page":"11","volume-title":"OpenID 2.0: a platform for user-centric identity management. Proceedings of the second ACM workshop on digital identity management","author":"D Recordon","year":"2006","unstructured":"Recordon D, Reed D. OpenID 2.0: a platform for user-centric identity management. Proceedings of the second ACM workshop on digital identity management. New York: ACM; 2006. p. 11\u20136."},{"key":"424_CR90","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1136\/amiajnl-2012-000906","volume":"20","author":"J Kwon","year":"2013","unstructured":"Kwon J, Johnson ME. Security practices and regulatory compliance in the healthcare industry. J Am Med Inform Assoc. 2013;20:44\u201351.","journal-title":"J Am Med Inform Assoc"},{"key":"424_CR91","doi-asserted-by":"publisher","unstructured":"Barkley J. Comparing simple role based access control models and access control lists. Proceedings of the second ACM workshop on Role-based access control. Fairfax: ACM; 1997. p. 127\u201332.","DOI":"10.1145\/266741.266769"},{"key":"424_CR92","unstructured":"R\u00f8stad L. Access control in healthcare information systems. Trondheim: Norwegian University of Science and Technology; 2008."},{"key":"424_CR93","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1197\/jamia.M2522","volume":"15","author":"S Oster","year":"2008","unstructured":"Oster S, Langella S, Hastings S, Ervin D, Madduri R, Phillips J, et al. caGrid 1.0: an enterprise Grid infrastructure for biomedical research. J Am Med Inform Assoc. 2008;15:138\u201349.","journal-title":"J Am Med Inform Assoc"},{"key":"424_CR94","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1136\/amiajnl-2014-002827","volume":"21","author":"AN Kho","year":"2014","unstructured":"Kho AN, Hynes DM, Goel S, Solomonides AE, Price R, Hota B, et al. CAPriCORN: Chicago area patient-centered outcomes research network. J Am Med Inform Assoc. 2014;21:607\u201311.","journal-title":"J Am Med Inform Assoc"},{"key":"424_CR95","doi-asserted-by":"publisher","first-page":"bau027","DOI":"10.1093\/database\/bau027","volume":"2014","author":"S Razick","year":"2014","unstructured":"Razick S, Mo\u010dnik R, Thomas LF, Ryeng E, Drabl\u00f8s F, S\u00e6trom P. The eGenVar data management system--cataloguing and sharing sensitive data and metadata for the life sciences. Database. 2014;2014:bau027.","journal-title":"Database"},{"key":"424_CR96","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1159\/000336673","volume":"15","author":"MJ Murtagh","year":"2012","unstructured":"Murtagh MJ, Demir I, Jenkings KN, Wallace SE, Murtagh B, Boniol M, et al. Securing the data economy: translating privacy and enacting security in the development of DataSHIELD. Public Health Genomics. 2012;15:243\u201353.","journal-title":"Public Health Genomics"},{"key":"424_CR97","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1136\/amiajnl-2012-001509","volume":"20","author":"BA Malin","year":"2013","unstructured":"Malin BA, Emam KE, O\u2019Keefe CM. Biomedical data privacy: problems, perspectives, and recent advances. J Am Med Inform Assoc. 2013;20:2\u20136.","journal-title":"J Am Med Inform Assoc"},{"key":"424_CR98","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1136\/amiajnl-2011-000316","volume":"18 Suppl 1","author":"SN Murphy","year":"2011","unstructured":"Murphy SN, Gainer V, Mendis M, Churchill S, Kohane I. Strategies for maintaining patient privacy in i2b2. J Am Med Inform Assoc. 2011;18 Suppl 1:103\u20138.","journal-title":"J Am Med Inform Assoc"},{"key":"424_CR99","doi-asserted-by":"publisher","first-page":"e55811","DOI":"10.1371\/journal.pone.0055811","volume":"8","author":"AJ McMurry","year":"2013","unstructured":"McMurry AJ, Murphy SN, MacFadden D, Weber G, Simons WW, Orechia J, et al. SHRINE: enabling nationally scalable multi-site disease studies. PLoS One. 2013;8:e55811.","journal-title":"PLoS One"},{"key":"424_CR100","doi-asserted-by":"publisher","first-page":"784","DOI":"10.1197\/jamia.M2985","volume":"16","author":"AD Boyd","year":"2009","unstructured":"Boyd AD, Saxman PR, Hunscher DA, Smith KA, Morris TD, Kaston M, et al. The university of Michigan honest broker: a Web-based service for clinical and translational research and practice. J Am Med Inform Assoc. 2009;16:784\u201391.","journal-title":"J Am Med Inform Assoc"},{"key":"424_CR101","doi-asserted-by":"publisher","first-page":"1144","DOI":"10.1186\/1471-2458-14-1144","volume":"14","author":"WG Panhuis van","year":"2014","unstructured":"van Panhuis WG, Paul P, Emerson C, Grefenstette J, Wilder R, Herbst AJ, et al. A systematic review of barriers to data sharing in public health. BMC Public Health. 2014;14:1144.","journal-title":"BMC Public Health"},{"key":"424_CR102","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1001\/jama.2009.958","volume":"302","author":"LM Lee","year":"2009","unstructured":"Lee LM, Gostin LO. Ethical collection, storage, and use of public health data: a proposal for a national privacy protection. JAMA. 2009;302:82\u20134.","journal-title":"JAMA"},{"key":"424_CR103","volume-title":"Code of ethics \u2013 updated version","author":"IMIA","year":"2016","unstructured":"IMIA. Code of ethics \u2013 updated version. 2016. http:\/\/imia-medinfo.org\/wp\/imia-code-of-ethics . Accessed 14 Feb 2017."},{"key":"424_CR104","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1136\/amiajnl-2012-001035","volume":"20","author":"KW Goodman","year":"2013","unstructured":"Goodman KW, Adams S, Berner ES, Embi PJ, Hsiung R, Hurdle J, et al. AMIA\u2019s code of professional and ethical conduct. J Am Med Inform Assoc. 2013;20:141\u20133.","journal-title":"J Am Med Inform Assoc"},{"key":"424_CR105","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1007\/s00439-014-1432-6","volume":"133","author":"BM Knoppers","year":"2014","unstructured":"Knoppers BM, Harris JR, Budin-Lj\u00f8sne I, Dove ES. A human rights approach to an international code of conduct for genomic and clinical data sharing. Hum Genet. 2014;133:895\u2013903.","journal-title":"Hum Genet"},{"key":"424_CR106","doi-asserted-by":"publisher","first-page":"11","DOI":"10.2310\/JIM.0b013e3181c9b2ea","volume":"58","author":"B Malin","year":"2010","unstructured":"Malin B, Karp D, Scheuermann RH. Technical and policy approaches to balancing patient privacy and data sharing in clinical and translational research. J Investig Med. 2010;58:11\u20138.","journal-title":"J Investig Med"},{"key":"424_CR107","doi-asserted-by":"publisher","first-page":"S3","DOI":"10.1186\/1472-6947-14-S1-S3","volume":"14 Suppl 1","author":"F Yu","year":"2014","unstructured":"Yu F, Ji Z. Scalable privacy-preserving data sharing methodology for genome-wide association studies: an application to iDASH healthcare privacy protection challenge. BMC Med Inform Decis Mak. 2014;14 Suppl 1:S3.","journal-title":"BMC Med Inform Decis Mak"},{"key":"424_CR108","doi-asserted-by":"publisher","first-page":"S1","DOI":"10.1186\/1472-6947-14-S1-S1","volume":"14 Suppl 1","author":"X Jiang","year":"2014","unstructured":"Jiang X, Zhao Y, Wang X, Malin B, Wang S, Ohno-Machado L, et al. A community assessment of privacy preserving techniques for human genomes. BMC Med Inform Decis Mak. 2014;14 Suppl 1:S1.","journal-title":"BMC Med Inform Decis Mak"},{"key":"424_CR109","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1126\/science.1095019","volume":"305","author":"Z Lin","year":"2004","unstructured":"Lin Z, Owen AB, Altman RB. Genetics. Genomic research and human subject privacy. Science. 2004;305:183.","journal-title":"Science"},{"key":"424_CR110","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1146\/annurev-genom-082410-101454","volume":"13","author":"J Kaye","year":"2012","unstructured":"Kaye J. The tension between data sharing and the protection of privacy in genomics research. Annu Rev Genomics Hum Genet. 2012;13:415\u201331.","journal-title":"Annu Rev Genomics Hum Genet"},{"key":"424_CR111","unstructured":"Public Population Project in Genomics and Society. http:\/\/www.p3g.org . Accessed 14 Feb 2017."},{"key":"424_CR112","unstructured":"International Society for Biological and Environmental Repositories. http:\/\/www.isber.org . Accessed 14 Feb 2017."},{"key":"424_CR113","unstructured":"BioSHaRE. http:\/\/www.bioshare.eu . Accessed 14 Feb 2017."},{"key":"424_CR114","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1038\/gim.2013.72","volume":"15","author":"O Gottesman","year":"2013","unstructured":"Gottesman O, Kuivaniemi H, Tromp G, Faucett WA, Li R, Manolio TA, et al. The electronic medical records and genomics (eMERGE) network: past, present, and future. Genet Med. 2013;15:761\u201371.","journal-title":"Genet Med"},{"key":"424_CR115","unstructured":"eMERGE Network. https:\/\/emerge.mc.vanderbilt.edu\/ . Accessed 14 Feb 2017."},{"key":"424_CR116","doi-asserted-by":"publisher","first-page":"1144","DOI":"10.1186\/s12911-016-0325-0","volume":"16","author":"W Kuchinke","year":"2016","unstructured":"Kuchinke W, Krauth C, Bergmann R, Karakoyun T, Woollard A, Schluender I, et al. Legal assessment tool (LAT): an interactive tool to address privacy and data protection issues for data sharing. BMC Med Inform Decis Mak. 2016;16:1144.","journal-title":"BMC Med Inform Decis Mak"},{"key":"424_CR117","unstructured":"Legal Assessment Tool (LAT). http:\/\/www.biomedbridges.eu\/sharing-sensitive-data . Accessed 14 Feb 2017."},{"key":"424_CR118","unstructured":"Human Sample Exchange Regulation Navigator. http:\/\/www.hsern.eu\/ . Accessed 14 Feb 2017."},{"key":"424_CR119","unstructured":"BBMRI Legal WIKI. http:\/\/www.bbmri-wp4.eu\/wiki\/index.php\/Main_Page . Accessed 14 Feb 2017."},{"key":"424_CR120","unstructured":"IPAC. http:\/\/p3g.org\/ipac . Accessed 14 Feb 2017."},{"key":"424_CR121","unstructured":"Web Services Single Sign On with Shibboleth. https:\/\/www.predic8.com\/shibboleth-web-services-sso-en.htm . Accessed 14 Feb 2017."},{"key":"424_CR122","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1038\/scientificamerican0501-34","volume":"284","author":"T Berners-Lee","year":"2001","unstructured":"Berners-Lee T, Tim B-L, James H, Ora L. The semantic Web. Sci Am. 2001;284:34\u201343.","journal-title":"Sci Am"},{"key":"424_CR123","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1109\/MIS.2009.102","volume":"24","author":"C Bizer","year":"2009","unstructured":"Bizer C. The emerging Web of linked data. IEEE Intell Syst. 2009;24:87\u201392.","journal-title":"IEEE Intell Syst"},{"key":"424_CR124","first-page":"1","volume":"5","author":"C Bizer","year":"2009","unstructured":"Bizer C, Christian B, Tom H, Tim B-L. Linked data - the story So Far. Int J Semant Web Inf Syst. 2009;5:1\u201322.","journal-title":"Int J Semant Web Inf Syst"},{"key":"424_CR125","unstructured":"McMurry J, Jupp S, Malone J, Burdett T, Jenkinson A, Parkinson H, et al. Report on the scalability of semantic web integration in BioMedBridges. BioMedBridges; 2015. http:\/\/dx.doi.org\/10.5281\/zenodo.14071 . Accessed 16 Mar 2017."},{"key":"424_CR126","doi-asserted-by":"publisher","unstructured":"Villata S, Serena V, Nicolas D, Fabien G, Amelie G. An Access Control Model for Linked Data. Lect Notes Comput Sci. 2011. p. 454\u201363.","DOI":"10.1007\/978-3-642-25126-9_57"},{"key":"424_CR127","volume-title":"Distributed SPARQL query answering over RDF data streams. 2013 IEEE international congress on Big data","author":"M Leida","year":"2013","unstructured":"Leida M, Marcello L, Andrej C. Distributed SPARQL query answering over RDF data streams. 2013 IEEE international congress on Big data. 2013. http:\/\/dx.doi.org\/10.1109\/bigdata.congress.2013.56 . Accessed 16 Mar 2017."},{"key":"424_CR128","doi-asserted-by":"publisher","first-page":"601","DOI":"10.1007\/978-3-642-25073-6_38","volume-title":"The semantic Web \u2013 ISWC 2011","author":"A Schwarte","year":"2011","unstructured":"Schwarte A, Haase P, Hose K, Schenkel R, Schmidt M, et al. FedX: optimization techniques for federated query processing on linked data. In: Aroyo L, Welty C, Alani H, Taylor J, Bernstein A, Kagal L, editors. The semantic Web \u2013 ISWC 2011. Berlin: Springer Berlin Heidelberg; 2011. p. 601\u201316."},{"key":"424_CR129","volume-title":"AARC: first draft of the blueprint architecture for authentication and authorisation infrastructures. ArXiv [cs.CR]","author":"A Biancini","year":"2016","unstructured":"Biancini A, Florio L, Haase M, Hardt M, Jankowski M, Jensen J, et al. AARC: first draft of the blueprint architecture for authentication and authorisation infrastructures. ArXiv [cs.CR]. 2016. http:\/\/arxiv.org\/abs\/1611.07832 . Accessed 16 Mar 2017."}],"container-title":["BMC Medical Informatics and Decision Making"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12911-017-0424-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,20]],"date-time":"2019-09-20T02:53:03Z","timestamp":1568947983000},"score":1,"resource":{"primary":{"URL":"http:\/\/bmcmedinformdecismak.biomedcentral.com\/articles\/10.1186\/s12911-017-0424-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,23]]},"references-count":129,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["424"],"URL":"https:\/\/doi.org\/10.1186\/s12911-017-0424-6","relation":{},"ISSN":["1472-6947"],"issn-type":[{"value":"1472-6947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3,23]]},"article-number":"30"}}