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However, predictors of LVRR are not fully understood. The left atrium (LA) has been reported as a prognostic predictor in patients with heart failure (HF). The present study aimed to evaluate clinical predictors of LVRR related to LA function on cardiac magnetic resonance (CMR).<\/jats:p>\n <\/jats:sec>\n Methods<\/jats:title>\n A total of 103 patients with reduced left ventricular ejection fraction (LVEF) were enrolled in this retrospective study between September 2015 and July 2021. CMR parameters, including strain data, were measured in all patients. Echocardiographic data obtained approximately 2 years after enrollment were analyzed to assess LVRR.<\/jats:p>\n <\/jats:sec>\n Results<\/jats:title>\n LVRR occurred in 46 patients (44.7%) during follow-up. The value of LA conduit strain was higher in the LVRR group than in the non-LVRR group (6.6 [interquartile range (IQR): 5.6\u20139.3]% versus 5.0 [IQR: 3.0-6.2]%; p<\/jats:italic>\u2009<\u20090.001). The multivariate logistic regression analysis showed that LA conduit strain was an independent predictor of LVRR (odds ratio [OR]: 1.216, 95% confidence interval [CI]: 1.050\u20131.408; p<\/jats:italic>\u2009=\u20090.009). The area under the receiver operating characteristic (ROC) curve of the LA conduit strain was 0.746, and the cutoff value was 6.2%. The Kaplan\u2012Meier analysis revealed that the incidence of adverse cardiac events was significantly lower in patients with LA conduit strain\u2009>\u20096.2% compared to those with \u2a7d6.2%. (log-rank test, p<\/jats:italic>\u2009=\u20090.019).<\/jats:p>\n <\/jats:sec>\n Conclusions<\/jats:title>\n LA conduit strain derived from CMR is an independent predictor of LVRR in patients with NICM.<\/jats:p>\n <\/jats:sec>","DOI":"10.1186\/s12880-023-01162-8","type":"journal-article","created":{"date-parts":[[2024,1,2]],"date-time":"2024-01-02T10:02:58Z","timestamp":1704189778000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Left atrial conduit strain derived from cardiac magnetic resonance is an independent predictor of left ventricular reverse remodeling in patients with nonischemic cardiomyopathy"],"prefix":"10.1186","volume":"24","author":[{"given":"Ke","family":"Chen","sequence":"first","affiliation":[]},{"given":"Lei","family":"Chang","sequence":"additional","affiliation":[]},{"given":"Rong","family":"Huang","sequence":"additional","affiliation":[]},{"given":"Ziyan","family":"Wang","sequence":"additional","affiliation":[]},{"given":"Dan","family":"Mu","sequence":"additional","affiliation":[]},{"given":"Lian","family":"Wang","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2024,1,2]]},"reference":[{"issue":"4","key":"1162_CR1","doi-asserted-by":"publisher","first-page":"2070","DOI":"10.1002\/ehf2.13939","volume":"9","author":"T Hnat","year":"2022","unstructured":"Hnat T, Veselka J, Honek J. 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The study was conducted following the ethical guidelines of the 1975 Declaration of Helsinki. Each patient provided written informed consent. Our database is not public, and the individual participant data will not be passed on.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"2"}}