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Such meshes arise in several application domains, such as 3D Geographic Information Systems (GISs), scientific visualization, and finite element analysis. To this aim, we propose\n Tetrahedral trees<\/jats:italic>\n , a family of spatial indexes based on a nested space subdivision (an octree or a kD-tree) and defined by several different subdivision criteria. We provide efficient algorithms for spatial and topological queries on Tetrahedral trees and compare to state-of-the-art approaches. Our results indicate that Tetrahedral trees are an improvement over R\n *<\/jats:sup>\n -trees for querying tetrahedral meshes; they are more compact, faster in many queries, and stable at variations of construction thresholds. They also support spatial queries on more general domains than topological data structures, which explicitly encode adjacency information for efficient navigation but have difficulties with domains with a non-trivial geometric or topological shape.\n <\/jats:p>","DOI":"10.1145\/3385851","type":"journal-article","created":{"date-parts":[[2020,6,3]],"date-time":"2020-06-03T10:06:08Z","timestamp":1591178768000},"page":"1-34","update-policy":"https:\/\/doi.org\/10.1145\/crossmark-policy","source":"Crossref","is-referenced-by-count":5,"title":["Tetrahedral Trees"],"prefix":"10.1145","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8758-2802","authenticated-orcid":false,"given":"Riccardo","family":"Fellegara","sequence":"first","affiliation":[{"name":"German Aerospace Center (DLR), Braunschweig, Germany"}]},{"given":"Leila De","family":"Floriani","sequence":"additional","affiliation":[{"name":"University of Maryland at College Park, MD"}]},{"given":"Paola","family":"Magillo","sequence":"additional","affiliation":[{"name":"University of Genova, Via Dodecaneso, Genova, Italy"}]},{"given":"Kenneth","family":"Weiss","sequence":"additional","affiliation":[{"name":"Lawrence Livermore National Laboratory, Livermore, CA"}]}],"member":"320","published-online":{"date-parts":[[2020,6,3]]},"reference":[{"key":"e_1_2_1_1_1","doi-asserted-by":"crossref","unstructured":"P. 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