{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T00:30:46Z","timestamp":1648686646193},"reference-count":22,"publisher":"World Scientific Pub Co Pte Lt","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Bioinform. Comput. Biol."],"published-print":{"date-parts":[[2010,8]]},"abstract":" Metal-ion binding proteins play a vital role in biological processes. Identifying putative metal-ion binding proteins is through knowledge-based methods. These involve the identification of specific motifs that characterize a specific class of metal-ion binding protein. Metal-ion binding motifs have been identified for the common metal ions. <\/jats:p> A robust global fingerprint that is useful in identifying a metal-ion binding protein from a non-metal-ion binding protein has not been devised. Such a method will help in identifying novel metal-ion binding proteins and proteins that do not possess a canonical metal-ion binding motif. We have used a set of physico-chemical parameters of metal-ion binding proteins encoded by the genes CzcA, CzcB and CzcD as a training set to supervised classifiers and have been able to identify several other metal ion binding proteins leading us to believe that metal-ion binding proteins have a global fingerprint, which cannot be pinned down to a single feature of the protein sequence. <\/jats:p>","DOI":"10.1142\/s0219720010004884","type":"journal-article","created":{"date-parts":[[2010,5,5]],"date-time":"2010-05-05T07:57:33Z","timestamp":1273046253000},"page":"717-726","source":"Crossref","is-referenced-by-count":4,"title":["GLOBAL METAL-ION BINDING PROTEIN FINGERPRINT: A METHOD TO IDENTIFY MOTIF-LESS METAL-ION BINDING PROTEINS"],"prefix":"10.1142","volume":"08","author":[{"given":"ABHILASH","family":"MOHAN","sequence":"first","affiliation":[{"name":"Centre for Biotechnology, Anna University, Chennai, Tamilnadu, 600 025, India"}]},{"given":"SHARMILA","family":"ANISHETTY","sequence":"additional","affiliation":[{"name":"Centre for Biotechnology, Anna University, Chennai, Tamilnadu, 600 025, India"}]},{"given":"PENNATHUR","family":"GAUTAM","sequence":"additional","affiliation":[{"name":"Centre for Biotechnology, Anna University, Chennai, Tamilnadu, 600 025, India"}]}],"member":"219","published-online":{"date-parts":[[2011,11,21]]},"reference":[{"key":"rf1","first-page":"175","volume":"66","author":"Hennig H.","journal-title":"Environ. 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