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{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,16]],"date-time":"2024-07-16T15:52:07Z","timestamp":1721145127616},"reference-count":28,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,10,5]],"date-time":"2020-10-05T00:00:00Z","timestamp":1601856000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100008530","name":"FEDER","doi-asserted-by":"publisher","award":["PEst\u2010UID\/CEC\/00027\/2020"],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Expert Systems"],"published-print":{"date-parts":[[2021,6]]},"abstract":"Abstract<\/jats:title>Knowledge Engineering has become essential in the fields of Medical and Health Care with emphasis for helping citizens to improve their health and quality of life. This includes individual methods and techniques in health\u2010related knowledge acquisition and representation and their application in the construction of intelligent systems capable of using the acquired information to improve the patients' health and\/or quality of life. Haemato\u2010oncological diseases can provide significant disability and suffering, with severe symptoms and psychological distress. They can create difficulties in fulfilling professional, family and social roles, affecting an individual's quality of life. Health related quality of life (HRQoL) is a subjective concept but there is also an objective component related to physiological indicators. Some of these physiological indicators can be easily assessed by wearable technology such heart rate variability (HRV). This paper introduces an intelligent system to assess, in real\u2010time, potential HRV indices, that can predict HRQoL in lymphoma patients throughout chemotherapy treatment and to account the individuals' variability. The system is based on wearable technology and intelligent processing of the patients' biometric information to assess some quality of life related parameters. A longitudinal study was conducted among 16 lymphoma patients using this intelligent system. Mixed\u2010effect regression models were performed to investigate predictors for and time effects on HRQoL. There were no significant changes in all HRQoL domains over time. Some quality of life domains revealed similar time trends as HRV indices. These HRV indices also have a significant effect on the domains of quality of life.<\/jats:p>","DOI":"10.1111\/exsy.12640","type":"journal-article","created":{"date-parts":[[2020,10,6]],"date-time":"2020-10-06T00:18:40Z","timestamp":1601943520000},"update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Biometrics and quality of life of lymphoma patients: A longitudinal mixed\u2010model<\/scp> approach"],"prefix":"10.1111","volume":"38","author":[{"given":"Alexandra","family":"Oliveira","sequence":"first","affiliation":[{"name":"LIACC \u2010 Artificial Intelligence and Computer Science Laboratory Porto Portugal"},{"name":"ESS\u2010IPP \u2010 Department of Biomathematics, Biostatistics and Bioinformatics, School of Health, Polytechnic Institute of Porto Porto Portugal"},{"name":"DEI\u2010FEUP \u2010 Department of Informatics Engineering, Faculty of Engineering University of Porto Porto Portugal"}]},{"given":"Eliana","family":"Silva","sequence":"additional","affiliation":[{"name":"LIACC \u2010 Artificial Intelligence and Computer Science Laboratory Porto Portugal"},{"name":"DEI\u2010FEUP \u2010 Department of Informatics Engineering, Faculty of Engineering University of Porto Porto Portugal"}]},{"given":"Joyce","family":"Aguiar","sequence":"additional","affiliation":[{"name":"LIACC \u2010 Artificial Intelligence and Computer Science Laboratory Porto Portugal"},{"name":"Centro ALGORITMI \u2013 University of Minho Guimar\u00e3es Portugal"}]},{"ORCID":"http:\/\/orcid.org\/0000-0003-2102-3407","authenticated-orcid":false,"given":"Br\u00edgida M\u00f3nica","family":"Faria","sequence":"additional","affiliation":[{"name":"LIACC \u2010 Artificial Intelligence and Computer Science Laboratory Porto Portugal"},{"name":"ESS\u2010IPP \u2010 Department of Biomathematics, Biostatistics and Bioinformatics, School of Health, Polytechnic Institute of Porto Porto Portugal"}]},{"given":"Lu\u00eds Paulo","family":"Reis","sequence":"additional","affiliation":[{"name":"LIACC \u2010 Artificial Intelligence and Computer Science Laboratory Porto Portugal"},{"name":"DEI\u2010FEUP \u2010 Department of Informatics Engineering, Faculty of Engineering University of Porto Porto Portugal"}]},{"given":"Henrique","family":"Cardoso","sequence":"additional","affiliation":[{"name":"LIACC \u2010 Artificial Intelligence and Computer Science Laboratory Porto Portugal"},{"name":"DEI\u2010FEUP \u2010 Department of Informatics Engineering, Faculty of Engineering University of Porto Porto Portugal"}]},{"given":"Joaquim","family":"Gon\u00e7alves","sequence":"additional","affiliation":[{"name":"LITEC \u2010 Lab. de Inova\u00e7\u00e3o Tecnol\u00f3gica e Engenharia do Conhecimento Porto Portugal"},{"name":"2Ai \u2010 Applied Artificial Intelligence Laboratory, School of Technology of Polytechnic Institute of C\u00e1vado and Ave Barcelos Portugal"}]},{"given":"Jorge","family":"Oliveira e S\u00e1","sequence":"additional","affiliation":[{"name":"Centro ALGORITMI \u2013 University of Minho Guimar\u00e3es Portugal"}]},{"given":"Victor","family":"Carvalho","sequence":"additional","affiliation":[{"name":"LITEC \u2010 Lab. de Inova\u00e7\u00e3o Tecnol\u00f3gica e Engenharia do Conhecimento Porto Portugal"}]},{"given":"Herlander","family":"Marques","sequence":"additional","affiliation":[{"name":"CINTESIS \u2010 Centro de Investiga\u00e7\u00e3o em Tecnologias e Servi\u00e7os de Sa\u00fade Porto Portugal"},{"name":"Centro Hospitalar de Braga Braga Portugal"}]}],"member":"311","published-online":{"date-parts":[[2020,10,5]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-22915-7_16"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrd.2017.153"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2008.20.0634"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2014.03.011"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/2193-1801-2-397"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0277-9536(95)00116-O"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2011.02.005"},{"key":"e_1_2_8_9_1","volume-title":"Getting started with RHRV, Version 2.0","author":"Garcia C.","year":"2014"},{"key":"e_1_2_8_10_1","doi-asserted-by":"crossref","unstructured":"Gon\u00e7alves J. Faria B. M. Reis L. P. Carvalho V. &Rocha \u00c1.(2015 June).Data mining and electronic devices applied to quality of life related to health data. Paper presented at 2015 10th Iberian Conference on Information Systems and Technologies (CISTI) (pp. 1\u20134). IEEE.","DOI":"10.1109\/CISTI.2015.7170627"},{"key":"e_1_2_8_11_1","doi-asserted-by":"crossref","unstructured":"Gon\u00e7alves J. Leit\u00e3o L. &Carvalho V.(2017 June).Analysis of the reliability and accuracy of a wearable device: Comparative study with a certified clinical device. Paper presented at 2017 12th Iberian Conference on Information Systems and Technologies (CISTI) (pp. 1\u20136). IEEE.","DOI":"10.23919\/CISTI.2017.7976034"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cct.2017.11.002"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/147176"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/clc.4960200214"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2018.00623"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.3109\/10428194.2011.563884"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcmj.2012.09.002"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.34024\/rnc.2013.v21.8171"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-65355-6"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.4081\/hpr.2013.932"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/2211-1522-3-1"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10916-018-0946-1"},{"key":"e_1_2_8_23_1","doi-asserted-by":"crossref","unstructured":"Reis L. P. Faria B. M. Gon\u00e7alves J. Rocha \u00c1. &Carvalho V.(2016 June).A survey on clinical decision support systems concerning quality of life. Paper presented at 2016 11th Iberian Conference on Information Systems and Technologies (CISTI) (pp. 1\u20138). IEEE.","DOI":"10.1109\/CISTI.2016.7521628"},{"key":"e_1_2_8_24_1","unstructured":"Servi\u00e7o Nacional de Sa\u00fade [Portuguese National Health Service] (SNS). (2018 November 30) Portal of SNS \u2010 Portuguese National Health Service Retrieved fromhttps:\/\/www.sns.gov.pt."},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2017.00258"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-16184-2_58"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.5964\/ejop.v9i1.337"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7525-1-79"},{"key":"e_1_2_8_29_1","unstructured":"World Health Organization (WHO). (2018 November 30) World Health Organization \u2010 Cancer Retrieved from.https:\/\/www.who.int\/cancer\/en"}],"container-title":["Expert Systems"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/exsy.12640","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/exsy.12640","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/exsy.12640","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,2]],"date-time":"2023-09-02T05:26:41Z","timestamp":1693632401000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/exsy.12640"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,5]]},"references-count":28,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["10.1111\/exsy.12640"],"URL":"https:\/\/doi.org\/10.1111\/exsy.12640","archive":["Portico"],"relation":{},"ISSN":["0266-4720","1468-0394"],"issn-type":[{"value":"0266-4720","type":"print"},{"value":"1468-0394","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,5]]},"assertion":[{"value":"2019-08-31","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-08-19","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}