乐胖代购免代理版

{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,10,6]],"date-time":"2024-10-06T01:06:16Z","timestamp":1728176776297},"reference-count":21,"publisher":"Oxford University Press (OUP)","issue":"D1","license":[{"start":{"date-parts":[[2020,12,12]],"date-time":"2020-12-12T00:00:00Z","timestamp":1607731200000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000038","name":"National Sciences and Engineering Research Council of Canada","doi-asserted-by":"crossref","award":["RGPIN 240644"],"id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Genome Canada and Genome British Columbia","award":["R03DIT"]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["20008571"],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Frederick Banting and Charles Best Canada Graduate Scholarship"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,1,8]]},"abstract":"Abstract<\/jats:title>Protein subcellular localization (SCL) is important for understanding protein function, genome annotation, and aids identification of potential cell surface diagnostic markers, drug targets, or vaccine components. PSORTdb comprises ePSORTdb, a manually curated database of experimentally verified protein SCLs, and cPSORTdb, a pre-computed database of PSORTb-predicted SCLs for NCBI\u2019s RefSeq deduced bacterial and archaeal proteomes. We now report PSORTdb 4.0 (http:\/\/db.psort.org\/). It features a website refresh, in particular a more user-friendly database search. It also addresses the need to uniquely identify proteins from NCBI genomes now that GI numbers have been retired. It further expands both ePSORTdb and cPSORTdb, including additional data about novel secondary localizations, such as proteins found in bacterial outer membrane vesicles. Protein predictions in cPSORTdb have increased along with the number of available microbial genomes, from approximately 13 million when PSORTdb 3.0 was released, to over 66 million currently. Now, analyses of both complete and draft genomes are included. This expanded database will be of wide use to researchers developing SCL predictors or studying diverse microbes, including medically, agriculturally and industrially important species that have both classic or atypical cell envelope structures or vesicles.<\/jats:p>","DOI":"10.1093\/nar\/gkaa1095","type":"journal-article","created":{"date-parts":[[2020,12,10]],"date-time":"2020-12-10T21:42:10Z","timestamp":1607636530000},"page":"D803-D808","source":"Crossref","is-referenced-by-count":24,"title":["PSORTdb 4.0: expanded and redesigned bacterial and archaeal protein subcellular localization database incorporating new secondary localizations"],"prefix":"10.1093","volume":"49","author":[{"ORCID":"http:\/\/orcid.org\/0000-0003-3884-4009","authenticated-orcid":false,"given":"Wing\u00a0Yin\u00a0Venus","family":"Lau","sequence":"first","affiliation":[{"name":"Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada"}]},{"given":"Gemma R","family":"Hoad","sequence":"additional","affiliation":[{"name":"Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada"}]},{"given":"Vivian","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada"}]},{"ORCID":"http:\/\/orcid.org\/0000-0001-6848-1638","authenticated-orcid":false,"given":"Geoffrey L","family":"Winsor","sequence":"additional","affiliation":[{"name":"Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada"}]},{"given":"Ashmeet","family":"Madyan","sequence":"additional","affiliation":[{"name":"Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada"}]},{"given":"Kristen L","family":"Gray","sequence":"additional","affiliation":[{"name":"Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada"}]},{"given":"Matthew R","family":"Laird","sequence":"additional","affiliation":[{"name":"Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada"}]},{"given":"Raymond","family":"Lo","sequence":"additional","affiliation":[{"name":"Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada"}]},{"given":"Fiona S L","family":"Brinkman","sequence":"additional","affiliation":[{"name":"Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada"}]}],"member":"286","published-online":{"date-parts":[[2020,12,11]]},"reference":[{"key":"2021010313124083300_B1","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1111\/1751-7915.12369","article-title":"Microbial protein: future sustainable food supply route with low environmental footprint","volume":"9","author":"Matassa","year":"2016","journal-title":"Microb. 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Microbiol."},{"key":"2021010313124083300_B9","doi-asserted-by":"crossref","first-page":"935736","DOI":"10.1155\/2013\/935736","article-title":"Cell envelope of corynebacteria: structure and influence on pathogenicity","volume":"2013","author":"Burkovski","year":"2013","journal-title":"ISRN Microbiol."},{"key":"2021010313124083300_B10","doi-asserted-by":"crossref","first-page":"D663","DOI":"10.1093\/nar\/gkv1271","article-title":"PSORTdb: expanding the bacteria and archaea protein subcellular localization database to better reflect diversity in cell envelope structures","volume":"44","author":"Peabody","year":"2016","journal-title":"Nucleic Acids Res."},{"key":"2021010313124083300_B11","doi-asserted-by":"crossref","first-page":"D164","DOI":"10.1093\/nar\/gki027","article-title":"PSORTdb: a protein subcellular localization database for bacteria","volume":"33","author":"Rey","year":"2005","journal-title":"Nucleic Acids Res."},{"key":"2021010313124083300_B12","doi-asserted-by":"crossref","first-page":"D241","DOI":"10.1093\/nar\/gkq1093","article-title":"PSORTdb\u2013an expanded, auto-updated, user-friendly protein subcellular localization database for Bacteria and Archaea","volume":"39","author":"Yu","year":"2011","journal-title":"Nucleic Acids Res."},{"key":"2021010313124083300_B13","doi-asserted-by":"crossref","first-page":"1947","DOI":"10.1093\/bioinformatics\/bts273","article-title":"MicrobeDB: a locally maintainable database of microbial genomic sequences","volume":"28","author":"Langille","year":"2012","journal-title":"Bioinformatics"},{"key":"2021010313124083300_B14","doi-asserted-by":"crossref","first-page":"D733","DOI":"10.1093\/nar\/gkv1189","article-title":"Reference sequence (RefSeq) database at NCBI: current status, taxonomic expansion, and functional annotation","volume":"44","author":"O\u2019Leary","year":"2016","journal-title":"Nucleic Acids Res."},{"key":"2021010313124083300_B15","doi-asserted-by":"crossref","DOI":"10.1128\/microbiolspec.PSIB-0001-2018","article-title":"Outer membrane vesicle-host cell interactions","volume":"7","author":"Cecil","year":"2019","journal-title":"Microbiol. 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