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Furthermore, genomic aberrations in cancer are especially difficult to handle because they are, by nature, unique to the patients. However, their recurrence in specific regions of the genome has been shown to reflect their relevance in the development of tumors. GREVE makes use of previously characterized events to identify such regions and focus any further analysis.<\/jats:p>\n Availability: GREVE is available through a web interface and open-source application (http:\/\/www.well.ox.ac.uk\/GREVE).<\/jats:p>","DOI":"10.1093\/bioinformatics\/bts547","type":"journal-article","created":{"date-parts":[[2012,9,9]],"date-time":"2012-09-09T00:29:08Z","timestamp":1347150548000},"page":"2981-2982","source":"Crossref","is-referenced-by-count":9,"title":["GREVE: Genomic Recurrent Event ViEwer to assist the identification of patterns across individual cancer samples"],"prefix":"10.1093","volume":"28","author":[{"given":"Jean-Baptiste","family":"Cazier","sequence":"first","affiliation":[{"name":"1 Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, OX3 7BN and 2Department of Statistics, University of Oxford, 1 South Parks Road, OX1 3TG, Oxford, UK"}]},{"given":"Chris C.","family":"Holmes","sequence":"additional","affiliation":[{"name":"1 Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, OX3 7BN and 2Department of Statistics, University of Oxford, 1 South Parks Road, OX1 3TG, Oxford, UK"},{"name":"1 Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, OX3 7BN and 2Department of Statistics, University of Oxford, 1 South Parks Road, OX1 3TG, Oxford, UK"}]},{"given":"John","family":"Broxholme","sequence":"additional","affiliation":[{"name":"1 Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, OX3 7BN and 2Department of Statistics, University of Oxford, 1 South Parks Road, OX1 3TG, Oxford, UK"}]}],"member":"286","published-online":{"date-parts":[[2012,9,6]]},"reference":[{"key":"2023012513224926700_bts547-B1","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1002\/gcc.20573","article-title":"Novel regions of acquired uniparental disomy discovered in acute myeloid leukemia","volume":"47","author":"Gupta","year":"2008","journal-title":"Genes Chromosomes Cancer"},{"key":"2023012513224926700_bts547-B2","article-title":"On computing the distribution function for the sum of independent and non-identical random indicators","volume-title":"Technical Reports","author":"Hong","year":"2011"},{"key":"2023012513224926700_bts547-B3","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1038\/ng1416","article-title":"Detection of large-scale variation in the human genome","volume":"36","author":"Iafrate","year":"2004","journal-title":"Nat. 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