{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,7]],"date-time":"2025-05-07T04:58:22Z","timestamp":1746593902217},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"18","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,9,15]]},"abstract":"Abstract<\/jats:title>Summary: Software programs that conduct genome-wide association studies and genomic prediction and selection need to use methodologies that maximize statistical power, provide high prediction accuracy and run in a computationally efficient manner. We developed an R package called Genome Association and Prediction Integrated Tool (GAPIT) that implements advanced statistical methods including the compressed mixed linear model (CMLM) and CMLM-based genomic prediction and selection. The GAPIT package can handle large datasets in excess of 10 000 individuals and 1 million single-nucleotide polymorphisms with minimal computational time, while providing user-friendly access and concise tables and graphs to interpret results.<\/jats:p>Availability: http:\/\/www.maizegenetics.net\/GAPIT.<\/jats:p>Contact: zhiwu.zhang@cornell.edu<\/jats:p>Supplementary Information: Supplementary data are available at Bioinformatics online.<\/jats:p>","DOI":"10.1093\/bioinformatics\/bts444","type":"journal-article","created":{"date-parts":[[2012,7,14]],"date-time":"2012-07-14T09:29:14Z","timestamp":1342258154000},"page":"2397-2399","source":"Crossref","is-referenced-by-count":1767,"title":["GAPIT: genome association and prediction integrated tool"],"prefix":"10.1093","volume":"28","author":[{"given":"Alexander E.","family":"Lipka","sequence":"first","affiliation":[{"name":"1 Computational Biologist with the United States Department of Agriculture - Agricultural Research Service (USDA-ARS), Ithaca, NY 14853, USA, 2Institute for Genomic Diversity, Cornell University, Ithaca, NY 14853, USA, 3Department of Animal Science, Shanghai Jiao Tong University, Shanghai 200240, China, 4Department of Plant Breeding and Genetics, Cornell University, Ithaca, NY 14853, USA, 5Centre of Pear Engineering Technology Research, Nanjing Agricultural University, Nanjing 210095, China and 6US Arid-Land Agricultural Research Center, United States Department of Agriculture-Agricultural Research Service, Maricopa, AZ 85138, USA"}]},{"given":"Feng","family":"Tian","sequence":"additional","affiliation":[{"name":"1 Computational Biologist with the United States Department of Agriculture - Agricultural Research Service (USDA-ARS), Ithaca, NY 14853, USA, 2Institute for Genomic Diversity, Cornell University, Ithaca, NY 14853, USA, 3Department of Animal Science, Shanghai Jiao Tong University, Shanghai 200240, China, 4Department of Plant Breeding and Genetics, Cornell University, Ithaca, NY 14853, USA, 5Centre of Pear Engineering Technology Research, Nanjing Agricultural University, Nanjing 210095, China and 6US Arid-Land Agricultural Research Center, United States Department of Agriculture-Agricultural Research Service, Maricopa, AZ 85138, USA"}]},{"given":"Qishan","family":"Wang","sequence":"additional","affiliation":[{"name":"1 Computational Biologist with the United States Department of Agriculture - Agricultural Research Service (USDA-ARS), Ithaca, NY 14853, USA, 2Institute for Genomic Diversity, Cornell University, Ithaca, NY 14853, USA, 3Department of Animal Science, Shanghai Jiao Tong University, Shanghai 200240, China, 4Department of Plant Breeding and Genetics, Cornell University, Ithaca, NY 14853, USA, 5Centre of Pear Engineering Technology Research, Nanjing Agricultural University, Nanjing 210095, China and 6US Arid-Land Agricultural Research Center, United States Department of Agriculture-Agricultural Research Service, Maricopa, AZ 85138, USA"}]},{"given":"Jason","family":"Peiffer","sequence":"additional","affiliation":[{"name":"1 Computational Biologist with the United States Department of Agriculture - Agricultural Research Service (USDA-ARS), Ithaca, NY 14853, USA, 2Institute for Genomic Diversity, Cornell University, Ithaca, NY 14853, USA, 3Department of Animal Science, Shanghai Jiao Tong University, Shanghai 200240, China, 4Department of Plant Breeding and Genetics, Cornell University, Ithaca, NY 14853, USA, 5Centre of Pear Engineering Technology Research, Nanjing Agricultural University, Nanjing 210095, China and 6US Arid-Land Agricultural Research Center, United States Department of Agriculture-Agricultural Research Service, Maricopa, AZ 85138, USA"}]},{"given":"Meng","family":"Li","sequence":"additional","affiliation":[{"name":"1 Computational Biologist with the United States Department of Agriculture - Agricultural Research Service (USDA-ARS), Ithaca, NY 14853, USA, 2Institute for Genomic Diversity, Cornell University, Ithaca, NY 14853, USA, 3Department of Animal Science, Shanghai Jiao Tong University, Shanghai 200240, China, 4Department of Plant Breeding and Genetics, Cornell University, Ithaca, NY 14853, USA, 5Centre of Pear Engineering Technology Research, Nanjing Agricultural University, Nanjing 210095, China and 6US Arid-Land Agricultural Research Center, United States Department of Agriculture-Agricultural Research Service, Maricopa, AZ 85138, USA"},{"name":"1 Computational Biologist with the United States Department of Agriculture - Agricultural Research Service (USDA-ARS), Ithaca, NY 14853, USA, 2Institute for Genomic Diversity, Cornell University, Ithaca, NY 14853, USA, 3Department of Animal Science, Shanghai Jiao Tong University, Shanghai 200240, China, 4Department of Plant Breeding and Genetics, Cornell University, Ithaca, NY 14853, USA, 5Centre of Pear Engineering Technology Research, Nanjing Agricultural University, Nanjing 210095, China and 6US Arid-Land Agricultural Research Center, United States Department of Agriculture-Agricultural Research Service, Maricopa, AZ 85138, USA"}]},{"given":"Peter J.","family":"Bradbury","sequence":"additional","affiliation":[{"name":"1 Computational Biologist with the United States Department of Agriculture - Agricultural Research Service (USDA-ARS), Ithaca, NY 14853, USA, 2Institute for Genomic Diversity, Cornell University, Ithaca, NY 14853, USA, 3Department of Animal Science, Shanghai Jiao Tong University, Shanghai 200240, China, 4Department of Plant Breeding and Genetics, Cornell University, Ithaca, NY 14853, USA, 5Centre of Pear Engineering Technology Research, Nanjing Agricultural University, Nanjing 210095, China and 6US Arid-Land Agricultural Research Center, United States Department of Agriculture-Agricultural Research Service, Maricopa, AZ 85138, USA"}]},{"given":"Michael A.","family":"Gore","sequence":"additional","affiliation":[{"name":"1 Computational Biologist with the United States Department of Agriculture - Agricultural Research Service (USDA-ARS), Ithaca, NY 14853, USA, 2Institute for Genomic Diversity, Cornell University, Ithaca, NY 14853, USA, 3Department of Animal Science, Shanghai Jiao Tong University, Shanghai 200240, China, 4Department of Plant Breeding and Genetics, Cornell University, Ithaca, NY 14853, USA, 5Centre of Pear Engineering Technology Research, Nanjing Agricultural University, Nanjing 210095, China and 6US Arid-Land Agricultural Research Center, United States Department of Agriculture-Agricultural Research Service, Maricopa, AZ 85138, USA"}]},{"given":"Edward S.","family":"Buckler","sequence":"additional","affiliation":[{"name":"1 Computational Biologist with the United States Department of Agriculture - Agricultural Research Service (USDA-ARS), Ithaca, NY 14853, USA, 2Institute for Genomic Diversity, Cornell University, Ithaca, NY 14853, USA, 3Department of Animal Science, Shanghai Jiao Tong University, Shanghai 200240, China, 4Department of Plant Breeding and Genetics, Cornell University, Ithaca, NY 14853, USA, 5Centre of Pear Engineering Technology Research, Nanjing Agricultural University, Nanjing 210095, China and 6US Arid-Land Agricultural Research Center, United States Department of Agriculture-Agricultural Research Service, Maricopa, AZ 85138, USA"},{"name":"1 Computational Biologist with the United States Department of Agriculture - 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